Wednesday, April 30, 2008

Visualization in Medicine and Life Sciences

Visualization in Medicine and Life Sciences (Mathematics and Visualization)
by Lars Linsen (Editor), Hans Hagen (Editor), Bernd Hamann (Editor)

Product Details
* Hardcover: 346 pages
* Publisher: Springer; 1 edition (November 12, 2007)
* Language: English
* ISBN-10: 3540726292

Book Description
Visualization technology is becoming increasingly important for medical and biomedical data processing and analysis. This technology complements traditional image processing methods as it allows scientists to visually interact with large, high- resolution three-dimensional image data, for example. Further, an ever increasing number of new data acquisition methods are being used in medicine and the life sciences, in particular in genomics and proteomics. This book discusses some of the latest visualization techniques and systems for effective analysis of such diverse, large, complex, and multi-source data.
Experts from all over the world had been invited to participate in a workshop held in July 2006 on the island RĂ¼gen in Germany. About 40 participants presented state-of-the-art research on the topic. Research and survey papers have been solicited and carefully refereed, resulting in this collection.
The topics covered include Segmentation and Feature Detection, Surface Extraction, Volume Visualization, Graph and Network Visualization, Visual Data Exploration, Multivariate and Multidimensional Data Visualization, Large Data Visualization.
The book will be of great interest to researchers, graduate students, and professionals dealing with visualization and its application in medicine and life sciences.

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Tuesday, April 29, 2008

The Springer Index of Viruses

The Springer Index of Viruses
by Christian A. Tidona (Editor), Gholamreza Darai (Editor)

Product Details
* Hardcover: 1400 pages
* Publisher: Springer; 1st edition (March 22, 2002)
* Language: English
* ISBN-10: 3540671676

Book Description
This comprehensive Encyclopedic Reference systematically integrates the state-of-the-art knowledge on all virus genera in the standardized format of lists, tables and figures. Each chapter provides highly structured and condensed information on a single virus genus and was contributed by one of the worlds leading experts in that particular field. Each of the 241 taxonomically ordered chapters includes detailed information on individual genus members, historical events, virion morphology, genome properties, replication strategy, properties of individual transcripts and proteins, sequence accession numbers, biological properties, diseases, recombinant vector constructs, vaccine strains, key references, as well as a high-resolution particle image and a drawing of the genome organization. Its high content of easily accessible detail information makes this Encyclopedic Reference an indispensable tool for both researchers and lecturers.

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Campylobacteriosis

Campylobacteriosis (Deadly Diseases and Epidemics)
by Bibiana Law (Author), I. Edward Alcamo (Author)

Product Details
* Hardcover: 112 pages
* Publisher: Chelsea House Publications; Library Binding edition (August 2004)
* Language: English
* ISBN-10: 079107899X

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Monday, April 28, 2008

Proteomics of Microbial Pathogens

Proteomics of Microbial Pathogens
by Peter R. Jungblut (Editor), Michael Hecker (Editor)

Product Details
* Hardcover: 343 pages
* Publisher: Wiley-VCH; 1 edition (March 30, 2007)
* Language: English
* ISBN-10: 3527317597

Book Description
High-quality research articles on proteomic analyses of microbial pathogens, made available in a handy form.
Containing proven, high-quality research articles selected from the popular Proteomics journal, this is a current overview of the latest research into the proteomics analysis of microbial pathogens as well as several review articles.

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Sunday, April 27, 2008

Drug Hypersensitivity

Drug Hypersensitivity
by W. j. Pichler (Editor)

Product Details
* Hardcover: 438 pages
* Publisher: Not Avail; 1 edition (May 31, 2007)
* Language: English
* ISBN-10: 3805582692

Book Description
Drug hypersensitivities are immune-mediated reactions characterized by exanthems, fever and internal organ involvement. They represent a challenging field of research: many different drugs can induce a variety of clinical symptoms through multiple mechanisms of drug-host interaction, many of which are poorly understood. This is the first book to approach the phenomenon of drug hypersensitivity in a comprehensive manner. Besides epidemiological aspects, it addresses the immunological mechanisms underlying these complicated reactions which go far beyond the IgE-mediated drug allergies also considered in the book. Furthermore, the book covers clinical manifestations and new diagnostic methods, and introduces some recently established animal models. Well-accepted and also completely new concepts are presented and discussed in detail. Many topics are treated from multiple perspectives, and the 33 chapters are thoroughly cross-referenced. This publication will be of immense value not only to allergologists, dermatologists and anyone prescribing medication, but also to scientists in a pharmaceutical industry challenged by the economic effects of failures in drug development or drug removal from the market. Elucidating the mechanisms of drug hypersensitivity will not only help to identify patients at risk but will also provide novel insights into the pathophysiology of numerous immune-mediated diseases.

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Saturday, April 26, 2008

Chromosomes: Organization and Function

Chromosomes: Organization and Function
by Adrian T. Sumner (Author)

Product Details
* Paperback: 304 pages
* Publisher: Wiley-Blackwell (February 3, 2003)
* Language: English
* ISBN-10: 0632054077

Book Description
Integrating classical knowledge of chromosome organisation with recent molecular and functional findings, this book presents an up-to-date view of chromosome organisation and function for advanced undergraduate students studying genetics. The organisation and behaviour of chromosomes is central to genetics and the equal segregation of genes and chromosomes into daughter cells at cell division is vital. This text aims to provide a clear and straightforward explanation of these complex processes.
Following a brief historical introduction, the text covers the topics of cell cycle dynamics and DNA replication; mitosis and meiosis; the organisation of DNA into chromatin; the arrangement of chromosomes in interphase; euchromatin and heterochromatin; nucleolus organisers; centromeres and telomeres; lampbrush and polytene chromosomes; chromosomes and evolution; chromosomes and disease, and artificial chromosomes. Topics are illustrated with examples from a wide variety of organisms, including fungi, plants, invertebrates and vertebrates. This book will be valuable resource for plant, animal and human geneticists and cell biologists.
Originally a zoologist, Adrian Sumner has spent over 25 years studying human and other mammalian chromosomes with the Medical Research Council (UK). One of the pioneers of chromosome banding, he has used electron microscopy and immunofluorescence to study chromosome organisation and function, and latterly has studied factors involved in chromosome separation at mitosis. Adrian is an Associate Editor of the journal Chromosome Research, acts as a consultant biologist and is also Chair of the Committee of the International Chromosome Conferences.

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Advances in Applied Microbiology, Volume 63

Advances in Applied Microbiology, Volume 63 (Advances in Applied Microbiology)
by Allen I. Laskin (Series Editor), Geoffrey M. Gadd (Series Editor), Sima Sariaslani (Series Editor)

Product Details
* Hardcover: 352 pages
* Publisher: Academic Press; 1 edition (April 1, 2008)
* Language: English
* ISBN-10: 0444531912

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Botulism

Botulism (Deadly Diseases and Epidemics)
by Donald Emmeluth (Author)

Product Details
* Reading level: Young Adult
* Library Binding: 136 pages
* Publisher: Chelsea House Publications; 1 edition (September 2005)
* Language: English

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Friday, April 25, 2008

Salmonella: A Practical Approach to the Organism and its Control in Foods

Salmonella: A Practical Approach to the Organism and its Control in Foods
by Chris Bell (Author), Alec Kyriakides (Author)

Product Details
* Paperback: 200 pages
* Publisher: Wiley-Blackwell; 1 edition (December 15, 2001)
* Language: English
* ISBN-10: 0632055197

Book Description
Human illness attributed to foodborne pathogenic microorganisms has been prominent in the mass media in recent years. The Practical Food Microbiology Series has been devised to give practical and accurate information about specific organisms of concern to public health. The information is designed for use by those in the food industry working in manufacturing, retailing and quality assurance, those in associated professional sectors e.g. public health, and students in each of these areas.
The series is unique in its practical approach as it draws on real life situations to highlight practical means for controlling the organism in foods.
Salmonella species are arguably the most commonly reported food associated human pathogens in the developed world. They are zoonotic agents and many different animal reservoirs are known. They can be found widely in the environment and may also establish in food processing environments. Over 2000 serotypes of Salmonella have been identified to-date, some of which cause very serious illness in humans particularly in vulnerable populations such as the elderly. Although rare, illness may result in fatality or long term debility and sequelae. Salmonella spp. are so widespread in raw foods and food source environments that the food industry has to maintain constant vigilance regarding contamination in raw materials, effectiveness of food processing systems and control of finished product characteristics for assuring food safety with respect to this important pathogen.
This book details the causes of selected outbreaks and assesses the lessons that can be learnt from them. It examines the characteristics of Salmonella spp. and identifies factors that make foods susceptible to contamination and growth of these organisms. Specific product sectors are used to indicate practical measures that can be applied to control Salmonella spp. in foods and minimise their potential to cause harm to the consumer. It also provides guidance in selecting effective sampling plans and test methods to monitor and detect the organism and offers pragmatic advice on action to be taken when the organism is detected during monitoring programmes.

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Avian Flu

Avian Flu (Deadly Diseases and Epidemics)
by Jeffrey N. Sfakianos (Author), I. Edward Alcamo (Author), David Heymann (Foreword)

Product Details
* Library Binding: 88 pages
* Publisher: Chelsea House Publications; 1 edition (April 30, 2006)
* Language: English
* ISBN-10: 0791086755

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Thursday, April 24, 2008

Antibiotic Resistant Bacteria

Antibiotic Resistant Bacteria (Deadly Diseases and Epidemics)
by Patrick, Ph.D. Guilfoile (Author), I. Edward Alcamo (Author)

Product Details
* Library Binding: 128 pages
* Publisher: Chelsea House Publications; 1 edition (December 30, 2006)
* Language: English
* ISBN-10: 0791091880

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Prevention of Allergy and Allergic Asthma

Prevention of Allergy and Allergic Asthma (Chemical Immunology)
by Johansson (Editor)

Product Details
* Hardcover: 224 pages
* Publisher: S. Karger AG (Switzerland); 1 edition (October 2004)
* Language: English
* ISBN-10: 3805578105

Book Description
In the western world, the prevalence of allergy and asthma has increased two- to threefold over the last 40 years and has reached epidemic proportions. This book represents the first complete document containing recommendations on the prevention of allergy and allergic asthma based on the current understanding of the immunological mechanisms of allergic reactions.Prevention of Allergy and Allergic Asthma was a collaborative project between the WAO (World Allergy Organization) and the WHO, launched in 1999. Following two interim reports, this monograph is the final report of the group of international experts involved in the project, ranging from basic immunologists to clinicians. Both theoretical and practical aspects are discussed, and constructive advice is given. Through its network of more than 70 member societies, the WAO will now promote the concept of prevention of allergies and allergic asthma worldwide to benefit patients prone to become allergic, to prevent the worsening.

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Wednesday, April 23, 2008

Fire Blight: The Disease and Its Causative Agent, Erwinia Amylovora

Fire Blight: The Disease and Its Causative Agent, Erwinia Amylovora
By Joel L. Vanneste

Product Details
* Hardcover: 388 pages
* Publisher: CABI (November 23, 2000)
* Language: English
* ISBN-10: 0851992943

Book Description
Fire blight is a major disease of apples, pears and certain woody ornamental plants. It is caused by the bacterium Erwinia Amylovora. Written by leading research workers from the USA, Europe and New Zealand, this book is the first comprehensive volume for twenty years to address this
subject.

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Handbook Of Drugs For Tropical Parasitic Infections

Handbook Of Drugs For Tropical Parasitic Infections
by Aden Abdi Yakoub (Author)

Product Details
* Paperback: 181 pages
* Publisher: CRC; 2 edition (November 21, 1995)
* Language: English
* ISBN-10: 0748401687

Book Description
Parasitic infections such as malaria, schistosomiasis, trypanosomiasis and onchoceriasis are the scourge of the tropical countries. Many of the drugs used for the treatment of tropical parasitic infections were introduced more than 30 years ago. Most of these drugs are toxic and have complicated dosage regimens, but, because of the low economic incentive, pharmaceutical companies have shown little interest in developing new drugs to control diseases prevalent in developing countries.; However, there has been notable progress in research into parasitic diseases and a number of important drugs have been introduced for some diseases since the 1970s. Moreover, recent data on the pharmacokinetics and field evaluations of these drugs have revealed that their effectiveness can be improved and their safety increased.; This handbook is designed to provide information about the pharmacological properties and therapeutic uses of the major drugs currently employed to combat the human parasitic infections encountered in the tropics. Each of the 38 drugs covered in the book are presented under the following headings: chemical structure, physical properties, pharmacology and mechanism of action, pharmacokinetics, clinical trials, pregnancy and lactation, side effects, contraindications and precautions, dosage, preparations, and references.

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Tuesday, April 22, 2008

The Cytokine Handbook

The Cytokine Handbook, Fourth Edition, Two Volume Set
by Angus W. Thomson (Editor), Michael T. Lotze (Editor)

Product Details
* Hardcover: 1536 pages
* Publisher: Academic Press; 4 edition (July 7, 2003)
* Language: English
* ISBN-10: 0126896631

Book Description
There are excellent chapters on cytokine genetics, chemokine nomenclature, and the basic biology of each of the cytokines

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Autoimmune Diseases in Endocrinology

Autoimmune Diseases in Endocrinology (Contemporary Endocrinology)
by Anthony P. Weetman (Editor)

Product Details
* Hardcover: 434 pages
* Publisher: Humana Press; 1 edition (December 11, 2007)
* Language: English
* ISBN-10: 1588297330

Book Description
Autoimmune Diseases in Endocrinology is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The text begins with three introductory chapters which provide sufficient information so that anyone, including those without a background in recent immunology, will be able to understand the developments in the field. The next and largest section of the book concerns autoimmune thyroid disease, and authors of these chapters take the reader through the basic epidemiology, genetic and environmental risk factors, immunopathogenesis, and the diagnostic and management aspect of the disease. The next section discusses Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies, including Addisons disease, premature ovarian failure, autoimmune hypophysitis, and autoimmune polyglandular syndrome types 1 and 2. Comprehensive and timely, Autoimmune Diseases in Endocrinology will become an essential reference for all endocrinologists and internal medicine practitioners working in this field.

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Monday, April 21, 2008

The Immune Synapse as a Novel Target for Therapy

The Immune Synapse as a Novel Target for Therapy (Progress in Inflammation Research)
By Luis Graca

Product Details
* Hardcover: 192 pages
* Publisher: BirkhĂƒ¤user Basel; 1 edition (December 10, 2007)
* Language: English
* ISBN-10: 3764382953

Book Description
The immune synapse can be compared to a molecular machine that controls T cell activation when getting in contact with an antigen-presenting cell (APC). The immune synapse is involved in the transfer of information across the T cell-APC junction. It plays an essential role in the control and nature of the immune response. In recent years several approaches have been developed to reprogramming the immune response by targeting molecules involved in the immune synapse. Monoclonal antibodies, such as the ones targeting the lymphocyte co-receptor, co-stimulatory and adhesion molecules (CD3, CD4, CD40L, CTLA4-Ig, ICAM-1), or altered peptide ligands have been shown capable of inducing immune tolerance in transplantation, autoimmunity and allergy. This volume gives an overview on the progress in the field, from basic science to clinical trials, and the major mechanisms involved. It discusses how interfering with T cell activation may lead to immune tolerance, immune modulation and the recruitment of regulatory T cells, the role of monoclonal antibodies in tolerance induction, and mechanisms maintaining dominant tolerance. The book is of interest to clinicians and researchers working in this area.

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Biological Control of Crop Diseases

Biological Control of Crop Diseases (Books in Soils, Plant and the Environment)
by Samuel S. Gnanamanickam (Editor)

Product Details
* Hardcover: 480 pages
* Publisher: CRC; 1st edition (April 3, 2002)
* Language: English
* ISBN-10: 0824706935

Book Description
With contributions from more than 30 internationally renowned experts, this book combines coverage of theory with coverage of global practices. Highlighting the day-to-day challenges of organic crop management for cost-effective real-world application, the book explores the biological control of diseases in 12 major crops. It focuses on the use of host plant resistance through transgenics and induced systemic resistance as a part of biological control. Topics covered include the role of biocontrol agents for signaling resistance, effective ecofriendly alternative to combat bacterial, fungal, and viral infestation, and transgenic crops in disease management.

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Sunday, April 20, 2008

Innate and Adaptive Immunity in the Tumor Microenvironment

Innate and Adaptive Immunity in the Tumor Microenvironment (The Tumor Microenvironment)
by Eitan Yefenof

Product Details
* Hardcover: 212 pages
* Publisher: Springer; 1 edition (February 2008)
* Language: English
* ISBN-10: 1402067496

Book Description
Cancer cells are continuously interacting with the immune system of the host. These interactions can be regarded as a double edged sword. On the one hand, innate and adaptive immune responses act to protect the host by attempting rejection of the tumor. On the other hand, inflammatory cells and proteins stimulate multiplication and dissemination of cancer cells, thereby accelerating the progression of the disease. Traditionally, the interplay between cancer cells and host immunity has been studied systemically, with no particular attention to the site at which a given tumor develops. Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host. Accordingly, microenvironmental immunity that operates inside and around a tumor plays a crucial role in cancer development and progression. The aim of the present volume is to compile reviews on innate and adaptive immune responses at the tumor microenvironment with emphasis on positive and negative outcomes that affect the progression of the disease. These reviews have been solicited from experts in the field who published original research studies focusing on these issues.

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Saturday, April 19, 2008

Opportunistic Infections: Toxoplasma, Sarcocystis, and Microsporidia

Opportunistic Infections: Toxoplasma, Sarcocystis, and Microsporidia (World Class Parasites)
by David S. Lindsay (Editor), Louis M. Weiss (Editor)

Product Details
* Hardcover: 256 pages
* Publisher: Springer; 1 edition (March 31, 2004)
* Language: English
* ISBN-10: 1402078145

Book Description
Opportunistic Infections: Toxoplasma, Sarcocystis, and Microsporidia will focus on two important Genera of Apicomplexan parasites, Toxoplasma gondii and Sarcocystis species, and the medically important members of the Phylum Microsporida. We have been fortunate in obtaining excellent contributions from many experts in the field.
Volumes in the "World Class Parasites" book series are written for researchers, students and scholars who enjoy reading about excellent research on problems of global significance. Each volume focuses on a parasite, or group of parasites, that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. The volumes are intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. They integrate vector, pathogen and host biology and celebrate the diversity of approach that comprises modern parasitological research.

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Chlamydia Atherosclerosis Lesion: Discovery, Diagnosis and Treatment

Chlamydia Atherosclerosis Lesion: Discovery, Diagnosis and Treatment
by Allan Shor (Author)

Product Details
* Hardcover: 170 pages
* Publisher: Springer; 1 edition (November 29, 2007)
* Language: English
* ISBN-10: 1846288096

Book Description
Dr Shor believes it is important for every medical practitioner to be aware of the new aspects of this disease, and that all facts concerning the circumstances, the finding of the germ, the specific pathological features and other aspects which change the concept of heart attacks, remarkably, methods of diagnoses of the lesion should all be known. Details and facets of the lesion are necessary for assessment, acceptance or rejection of this very important new disease, by the scientific community. It opens up new diagnosis and treatments, with potential cure and eradication of this deadly disease. Immunization or eradication of this germ if possible will open new horizons.

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Friday, April 18, 2008

Medical Mycology: Cellular and Molecular Techniques

Medical Mycology: Cellular and Molecular Techniques
by Kevin Kavanagh (Editor)

Product Details
* Hardcover: 348 pages
* Publisher: Wiley; 1 edition (December 18, 2006)
* Language: English
* ISBN-10: 0470019239

Book Description
Medical Mycology: Cellular and Molecular techniques is a clear and concise overview of the subject that details the techniques essential for ongoing research in the area. Drawing together contributions from both scientists and clinicians working in the field, the text will provide a valuable perspective on the applicability of specific techniques to patient care.
A wide range of molecular, immunological and cytological techniques are discussed throughout, with the inclusion of protocol section in each chapter designed to provide both a background a up-to-date account of the applications of each procedure. Every technique is fully referenced and illustrations are provided where required to enhance student understanding.
* comprehensive introduction to the key techniques critical to the study of medical mycology
* clear explanation of how each technique is applied in the lab
* contributions from internationally recognised experts in the field
* outlines the background to many techniques required for the successful completion of a research project
An invaluable reference for students of microbiology, biochemistry and molecular biology as well as postgraduates and researchers in the field of medical mycology looking for an up-to-date overview of the latest laboratory techniques.

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Microbial Fundamentals of Biotechnology

Microbial Fundamentals of Biotechnology
by Volkmar Braun (Editor), Friedrich Götz (Editor)

Product Details
* Hardcover: 377 pages
* Publisher: Wiley-VCH (March 19, 2002)
* Language: English
* ISBN-10: 3527306153

Book Description
The book reports research results from different disciplines.Topics include isolation and structure determination of new antibiotics and other biologically active secondary metabolites, biosynthesis of antibiotics in particular lantibiotics, nikkomycins and glycosyl antibiotics, mode of action of bacterial protein toxins, import and export of proteins, active transport and regulation of iron, the enzymology of murein biogenesis and morphogenesis, mode of action and biosynthesis of hopanoids, and second messenger systems of Paramecium.
The book gives answers to questions: how to use the biosynthetic abilities of micro-organisms to produce new biologically active compounds, how to synthesize (microbiologically or chemically) new structures, and how to test their biological activities.

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Thursday, April 17, 2008

Handbook of Dendritic Cells: Biology, Diseases and Therapies

Handbook of Dendritic Cells: Biology, Diseases and Therapies (3 Volume )
by Manfred B. Lutz (Editor), Nikolaus Romani (Editor), Alexander Steinkasserer (Editor), Ralph M. Steinman (Introduction)

Product Details
* Hardcover: 1290 pages
* Publisher: Wiley-VCH; 1 edition (April 17, 2006)
* Language: English
* ISBN-10: 3527311092

Book Description
This is the most comprehensive handbook on dendritic cells, featuring an introduction by Ralph M. Steinman and written by top experts. In three volumes, it covers all aspects from molecular cell biology to clinical applications, highlighting the role of dendritic cells in fighting cancer, virus infections, and autoimmune diseases.
The first section on cell biology looks at dendritic cell development, circulating cells, T cell priming, Th1 and Th2 decision and CTL priming. A second part on dendritic cells in disease deals with parasites, bacteria, viruses, autoimmunity, allergies, asthma and cancer. The final section on therapeutic applications includes viral infections and antigen delivery.

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Cancer Vaccines and Tumor Immunity

Cancer Vaccines and Tumor Immunity
by Rimas Orentas (Author), James W. Hodge (Author), Bryon D., PhD Johnson (Author)

Product Details
* Hardcover: 334 pages
* Publisher: Wiley-Liss; 1 edition (February 8, 2008)
* Language: English
* ISBN-10: 0470074744

Book Description
Cancer vaccine development has changed from a small-scale academic enterprise in to an applied science requiring a large clinical research infrastructure. In this book, a team of expert contributors take a focused look at the hot emerging area of cancer vaccines and tumor immunity. Cancer Vaccines and Tumor Immunity serves a unique role in that it presents as a continuum the basic science discoveries that have moved forward into clinical trials. It is a one-stop, concise reference for all those interested in cancer vaccines, summarizing where we have come from, demonstrating what we are currently doing, and identifying the next major advances.
* Discusses how our new and developing understanding of T-regulatory cells and autoimmunity will impact cancer vaccine design
* Offers a unique look forward into how vaccination in the context of bone marrow transplantation will open new avenues for clinical study
* Offers an exceptional presentation of how modern genomic analysis of normal and tumor tissue will help to identify the next generation of cancer vaccine targets

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Kurzlehrbuch Medizinische Mikrobiologie (German)

Kurzlehrbuch Medizinische Mikrobiologie (German)
by Uwe Gross (Author)

Product Details
* Perfect Paperback: 513 pages
* Publisher: Thieme Georg Verlag (October 31, 2006)
* ISBN-10: 3131416513
* ISBN-13: 978-3131416513

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Wednesday, April 16, 2008

Handbook of Listeria Monocytogenes

Handbook of Listeria Monocytogenes
by Dongyou Liu (Editor)

Product Details
* Hardcover: 552 pages
* Publisher: CRC (April 16, 2008)
* Language: English
* ISBN-10: 1420051407

Book Description
Once feared as a deadly intracellular bacterium with the extraordinary capacity to survive a wide array of arduous external stressors, Listeria monocytogenes is increasingly recognized as a preferred vector for delivering anti-infective and anti-cancer vaccine molecules.
A reliable, single-source reference on the fundamental aspects of this bacterium is crucial to support future study and further the advancement of biomedical sciences and intervention strategies.
Drawn from an international panel of scientists with notable expertise in their respective fields, the Handbook of Listeria monocytogenes is divided into four sections:
Section I discusses the biology and pathogenicity of this bacterium, including epidemiology and stress responses.
Section II demonstrates identification and detection techniques such as phenotypic and genotypic identification, strain typing, and virulence determination.
Section III details the current knowledge of genetic manipulation of Listeria, including comparative genomics, genomic divisions, epidemic clones and population structure, and analysis of cell envelope proteins.
Section IV covers innate and adaptive immunity against Listeria, and examines the use of this bacterium for anti-infective and anti-cancer vaccine development.
The first comprehensive compilation of knowledge in this area, this handbook is an indispensable reference for anyone embarking on the path of manipulation of Listeria as either a model for the study of the host-bacterium relationship or as a tool for delivering protective molecules to cytoplasm.

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Dictionary of Microbiology & Molecular Biology

Dictionary of Microbiology & Molecular Biology
by Paul Singleton (Author), Diana Sainsbury (Author)

Product Details
* Paperback: 908 pages
* Publisher: Wiley; 3 edition (November 3, 2006)
* Language: English
* ISBN-10: 0470035455

Book Description:
This Third, Revised Edition of a unique, encyclopaedic reference work covers the whole field of pure and applied microbiology and microbial molecular biology in one volume. The Dictionary of Microbiology and Molecular Biology, Third Edition, Revised:
* Reflects the latest developments in the field
* Features over 18,000 entries from concise definitions of terms to review-length articles
* Provides extensive cross-referencing between topics
* Includes numerous references from scientific journals and other relevant sources
With its wide-ranging description of different areas of microbiology, the Dictionary of Microbiology and Molecular Biology, Third Edition, Revised is an indispensable reference for every researcher, lecturer and student.

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Tuesday, April 15, 2008

Recombinant Proteins, Monoclonal Antibodies & Therapeutic Genes

Recombinant Proteins, Monoclonal Antibodies & Therapeutic Genes
by A. Mountain (Editor), U. M. Ney (Editor), Dietmar Schomburg (Editor)

Product Details
* Hardcover: 562 pages
* Publisher: Wiley-VCH; 2 edition (April 15, 1999)
* Language: English
* ISBN-10: 3527283153

Book Description
In the field of medicinal biotechnology three major developments have caused a revolution in research that has a lot of innovative effects on clinical medicine and future applications on humans. With the availability of tailored recombinant proteins and the opportunity to produce high amounts of monoclonal antibodies new diagnostic applications have emerged and many therapeutic perspectives, e.g. in the treatment of multiple sclerosis and of cancer, are being discussed today.
The aim of somatic gene therapy is to re-establish normal cell function by supplying the cells with the respective intact gene. This is a very difficult task and different diseases, e.g. AIDS and several metabolic disorders, are under investigation now. So far first promising approaches exist in cancer therapy.
Moreover the book informs about regulatory and economic aspects of these new methods and their applications.

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Handbook of Therapeutic Antibodies

Handbook of Therapeutic Antibodies
by Stefan DĂ¼bel (Editor)

Product Details
* Hardcover: 1228 pages
* Publisher: Wiley-VCH; 1 edition (March 26, 2007)
* Language: English
* ISBN-10: 3527314539

Book Description
In this most comprehensive reference source for the development, production and therapeutic application of antibodies, Volume I contains general chapters presenting established technologies and clinical applications. Volume II provides a look at emerging technologies, new therapeutic concepts, and clinical studies. The third volume features detailed and specific information about each currently approved type of antibody, including the clinical data.
A must-have resource for academic researchers, decision makers in industry and healthcare professionals in the clinic.

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Monday, April 14, 2008

The Autoimmune Diseases

The Autoimmune Diseases, Fourth Edition
by Noel Richard Rose (Editor), Ian R. Mackay (Editor)

Product Details
* Hardcover: 1160 pages
* Publisher: Academic Press; 4 edition (March 27, 2006)
* Language: English
* ISBN-10: 0125959613

Book Description:
Since publication of the Third Edition in 1998, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This Fourth Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels.
New to This Edition:
* Tissue-specific interventions to arrest or "cure" autoimmune disease
* Bone marrow eradication and replacement
* Both basic science and clinical medicine is covered
* Boxed points to emphasize key features of each chapter

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Modern Multidisciplinary Applied Microbiology: Exploiting Microbes and Their Interactions

Modern Multidisciplinary Applied Microbiology: Exploiting Microbes and Their Interactions
by Antonio Mendez-Vilas (Editor)

Product Details
* Hardcover: 820 pages
* Publisher: Wiley-VCH; 1 edition (October 27, 2006)
* Language: English
* ISBN-10: 3527316116

Book Description
Indexed and cross-referenced interdisciplinary contributions provide an integrated view of the this thriving and important field, with reports on key research from the frontiers of applied microbiology. Topics include food, environmental, industrial, pharmaceutical, medical, bioinformatics and education sciences.

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Sunday, April 13, 2008

Complement Regulatory Proteins

Complement Regulatory Proteins
by B. Paul Morgan (Author), Claire L. Harris (Author)

Product Details
* Hardcover: 382 pages
* Publisher: Academic Press; 1st edition (April 15, 1999)
* Language: English
* ISBN-10: 0125069650

Book Description
From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book does just that. The first few chapters discuss the "nuts-and-bolts" of the complement regulators, describing their structures, functional roles and modes of action. The roles of the complement regulators in vivo are then described, focusing on the consequences of deficiency, roles in the reproductive system, interactions with pathogens and exploitation for therapy. The interesting developments in defining the complement regulators expressed in other species are also discussed. The book is written as a monograph, albeit by two people. The text is as readable as possible without compromising on scientific accuracy and completeness. The conversational style very evident in some sections is deliberate! Placing all references in a single bibliography at the end of the text further improves readability. The reader will go to the book to discover a specific fact but be persuaded to read more and derive pleasure from the process. The authors' enthusiasm for the subject comes over strongly in the text, and this enthusiasm proves infectious.

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Cheese: Chemistry, Physics & Microbiology, Two-Volume Set

Cheese: Chemistry, Physics & Microbiology, Two-Volume Set, Volume 1-2, Third Edition
by Patrick F. Fox (Editor), Paul McSweeney (Editor), Timothy Cogan (Editor), Timothy Guinee (Editor)

Product Details
* Hardcover: 1056 pages
* Publisher: Academic Press; 3 edition (October 8, 2004)
* Language: English
* ISBN-10: 0122636511

Book Description
The market for cheese as a food ingredient has increased rapidly in recent years and now represents upto approximately 50% of cheese production in some countries. This third edition of the highly successful two-volume work on the scientific aspects of Cheese: Chemistry, Physics, and Microbiology is available in two volumes entitled General Aspects and Major Cheese Groups. This title contains up-to-date reviews of the literature on the chemical, biochemical, microbiological and physico-chemical aspects of cheese in general. Volume one will focus on general aspects on the principles of cheese science, while volume two focuses on major cheese groups which is devoted to the characteristics of the principle families of cheese.

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Saturday, April 12, 2008

Immunbiologie: Eine EinfĂ¼hrung [German]

Immunbiologie: Eine EinfĂ¼hrung [German]
by JĂ¼rgen Neumann

Product Details
* Hardcover: 286 pages
* Publisher: Springer; 1 edition (January 21, 2008)
* Language: German
* ISBN-10: 3540725687

Book Description
Wie funktioniert die Immunantwort? Was sind Effektorreaktionen?
JĂ¼rgen Neumann fĂ¼hrt die Studenten der Biologie, Medizin, Biomedizin und Biochemie in die Grundlagen der Immunbiologie ein. DarĂ¼ber hinaus geht er auf wichtige aktuelle Themen, wie Autoimmunität, Allergie und AIDS ein. Auch wesentliche Prinzipien der Immunität von Invertebraten und prinzipielle Fragen nach der Steuerung von Immunantworten sind ein Thema.
FĂ¼r alle wissenschaftlich Interessierten, die Ă¼ber elementare Kenntnisse in Biologie und Biochemie verfĂ¼gen, ist dieses Buch eine ideale EinfĂ¼hrung in die Immunbiologie.

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Angewandte Mikrobiologie (German)

Angewandte Mikrobiologie (German)
by Garabed Antranikian (Editor)

Product Details
* Hardcover: 536 pages
* Publisher: Springer; 1 edition (September 21, 2005)
* Language: German
* ISBN-10: 3540240837

Book Description
Dieses Lehrbuch stellt erstmalig eine interdisziplinäre und innovationsträchtige Querschnittswissenschaft vor. Das Ziel ist, neue Umwelt schonende Prozesse und Produkte im Bereich Life Science zu erschlieĂŸen. Die jährliche Steigerungsrate mikrobieller Produkte (Chemikalien, Vitamine, Biopolymere, Brennstoffe) beträgt zwischen 10 und 20%. Die Angewandte Mikrobiologie ist damit eine der am stärksten wachsenden neuen Technologien.

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Furunculosis: Multidisciplinary Fish Disease Research

Furunculosis: Multidisciplinary Fish Disease Research
by Eva-Maria Bernoth (Editor), Anthony E. Ellis (Editor), Paul J. Midtlyng (Editor), Gilles Olivier (Editor), Peter Smith (Editor)

Product Details
* Hardcover: 529 pages
* Publisher: Academic Press; 1 edition (February 17, 1997)
* Language: English
* ISBN-10: 0120930404

Book Description:
Furunculosis: Multidisciplinary Fish Disease Research presents a fascinating insight into the opinions and the controversies which have led to current knowledge of this disease. It is the first book to cover one single fish disease by presenting not just the reviews, but also critical examination of the progress made by various disciplines. The multidisciplinary approach of the book makes it a valuable guide for veterinarians, fisheries biologists, and fish farm managers, as well as an excellent instructional text for students. The volume explores current research strategies and projects what developments can be expected in each field.

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Friday, April 11, 2008

Plasmids for Therapy and Vaccination

Plasmids for Therapy and Vaccination
By Martin Schleef

Product Details
* Hardcover: 320 pages
* Publisher: Wiley-VCH; 1 edition (February 13, 2001)
* Language: English
* ISBN-10: 3527302697

Book Description
This is the first book specializing in plasmids and their biomedical use, including all relevant aspects of production, applications, quality, and regulations. Readers will discover clinical applications for the wide range of preventive and therapeutic applications using plasmid DNA. The book describes modified vector systems based on plasmids, as well as the potency of genomic research and vector design by informatics. Using the example of fish vaccination, the application of DNA vaccination in veterinary health care is reviewed, followed by a detailed overview of plasmid production technology on an industrial scale. Finally, the book considers regulatory and quality assurance aspects of such new drugs plus thire market potential.

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How the Immune System Recognizes Self and Nonself

How the Immune System Recognizes Self and Nonself: Immunoreceptors and Their Signaling
by Daisuke Kitamura

Product Details
* Hardcover: 251 pages
* Publisher: Springer; 1 edition (February 15, 2008)
* Language: English
* ISBN-10: 4431738835

Book Description

The immune system is a highly evolved security system that protects the body from infection by pathogens such as viruses and bacteria. The immune system also recognizes and rejects a transplanted organ from even the same species. Indeed, the immune system potentially recognizes and eliminates everything that invades the body (nonself). However, it does not normally eliminate self cells or tissues except tumor cells developed from self tissue. Occasionally the immune system breaks down and attacks the body components of the self, manifesting as autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, myasthenia gravis, and insulin-resistant diabetes. This book contains extensive updated reviews describing what kinds of receptors various immune cells use, how they recognize the self and the nonself components (and neoself such as tumors), and how finally the immune system distinguishes the self and nonself - a far more complicated process than a computer security system detecting infected documents. Perfect understanding of this system should make it possible in the future to regulate immunity to transplants, to cure autoimmune disease and allergy, and to facilitate tumor immunity.

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Thursday, April 10, 2008

Mycotoxins in Foodstuff

Mycotoxins in Foodstuff
by Martin Weidenbörner (Author)

Product Details
* Hardcover: 503 pages
* Publisher: Springer; 1 edition (November 26, 2007)
* Language: English
* ISBN-10: 0387736883

Book Description
Due to the serious spoilage and health issues the presence of mycotoxins can cause, its imperative that the food industry has a basic understanding fungi and their corresponding mycotoxins.
An indispensable resource, Mycotoxins in Foodstuff gives an in depth overview by listing the degree of contamination, concentration and country of origin/detection for each case of mycotoxin contamination for each commodity. In addition, the book shows whether or not food is predisposed for mycotoxin contamination.

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Imaging of Parasitic Diseases

Imaging of Parasitic Diseases
by A.L. Baert (Foreword), Maurice C. Haddad (Editor), Mohamed E. Abd El Bagi (Editor), Jean C. Tamraz (Editor)

Product Details
* Hardcover: 198 pages
* Publisher: Springer; 1 edition (November 20, 2007)
* Language: English
* ISBN-10: 3540493530

Book Description
This book is dedicated to illustrate the imaging findings of parasitic diseases that can affect the human body using modern imaging equipments. Every chapter consists of a short description of causative agent, epidemiology, clinical manifestations, laboratory tests, imaging findings with illustrative examples of parasitic diseases that can affect the various systems of the human body. At the end of each chapter there will be a table summarizing key diagnostic features and relevant data pertinent to diagnosis. The parasitic diseases are increasing worldwide and this book is intended to give the reader, particularly radiologists, relevant clinical and imaging diagnostic features for diagnosis of parasitic diseases.

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Wednesday, April 9, 2008

The Macrophage

The Macrophage
by Bernard Burke (Editor), Claire E. Lewis (Editor)

Product Details
* Hardcover: 680 pages
* Publisher: Oxford University Press, USA; 2 edition (August 15, 2002)
* Language: English
* ISBN-10: 0192631977

Book Description
The field of macrophage research has grown enormously since publication of the first edition of this book. The Macrophage 2e provides a unique comprehensive review of the current scientific knowledge of the multifaceted role of this important and intriguiging cell in health and disease. In 16
chapters by experts in the field it covers the basic biology and diverse functions of macrophages in specific diseases and the complex of interactions between macrophages and other cells. Ranging from their role in the defense against pathogens, their role as hosts for pathogens (including HIV),
their complex roles in diseases such as arthritis and cancer, and their potential for use in novel gene therapy approaches to disease treatment, the book gives an up to the minute account of active macrophage research. The editors have intentionally included a broad rangeof topics that will appeal
not only to immunologists and cell biologists but will also be of interest to those working in the specific disease areas covered.

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Human Antibody Therapeutics For Viral Disease

Human Antibody Therapeutics For Viral Disease (Current Topics in Microbiology and Immunology)
by Scott K. Dessain (Editor)

Product Details
* Hardcover: 190 pages
* Publisher: Springer; 1 edition (December 6, 2007)
* Language: English
* ISBN-10: 3540721444

Book Description
Although the utility of human antibodies as medical therapeutics for cancer and immune diseases has been well-established, it is only beginning to be realized for the treatment of viral infectious diseases. Polyclonal immunoglobulins have long been used for some viral diseases, but they have limited potency and disease scope. It should theoretically be possible to create monoclonal or oligoclonal antibody preparations that capture the essential curative functions of the humoral immune response to viral pathogens, yet only a single humanized monoclonal antibody (pavilizumab) has been approved as a viral countermeasure. Reliable technologies for creating human or humanized antibodies with defined viral antigen specificities are well-established. Accordingly, current antibody development efforts are focused on identifying and cloning the particular antibodies that contain the fundamental curative potency of the polyclonal humoral immune response.

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Tuesday, April 8, 2008

Fungi: Biology and Applications

Fungi: Biology and Applications
by Kevin Kavanagh (Editor)

Product Details
* Hardcover: 280 pages
* Publisher: Wiley; 1 edition (June 17, 2005)
* Language: English
* ISBN-10: 0470867019

Book Description
Fungi: Biology and Applications is a comprehensive, balanced introduction of the biology, biotechnological applications and medical significance of fungi. With no prior knowledge of the subject assumed, the opening chapters offer a broad overview of the basics of fungal biology, in particular the physiology and genetics of fungi. Later chapters move on to include more detailed coverage of topics such as proteomics, bioinformatics, heterologous protein expression, medical mycology, anti-fungal drug development and function, fungal biotechnology and fungal pathogens of economically important plants.
Carefully structured, each chapter contains self-assessment exercises with answers included at the end of the book to enhance student understanding.
* A comprehensive treatment of the medical and economic importance of fungi to everyday life
* Chapters include revision sections and problems to reinforce key concepts
* Invaluable for undergraduates taking a first course on fungal biology or mycology.
* also of interest to those working within the field looking for an up-to-date introduction.

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Pathogenic Fungi in Humans and Animals

Pathogenic Fungi in Humans and Animals, Second Edition
by D.H. Howard (Editor)

Product Details
* Hardcover: 800 pages
* Publisher: CRC; 2 edition (October 30, 2002)
* Language: English
* ISBN-10: 0824706838

Book Description
Exploring breakthroughs in fungal detection and control, this book covers fungal nomenclature, population instability, and phylogeny, as well as investigative research on Peronosporomycetes, Zygomycetes, Filamentous Ascomycetes, Basidiomycetous Yeasts, Endomycetes and Blastomycetes, and Miscellaneous Opportunistic Fungi. It offers methods to identify zoopathogenic fungi, analyze reports of putative pathogens, develop methods for detection, isolation, and characterization of pathogenic fungi, evaluate emerging strain-typing techniques, target molecules for diagnostic tests, and examine the patterns and mechanisms of genetic variation.

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Monday, April 7, 2008

HIV/AIDS and the Nervous System

HIV/AIDS and the Nervous System: Handbook of Clinical Neurology
by Peter Portegies (Editor), Joseph Berger (Editor)

Product Details
* Paperback: 384 pages
* Publisher: Elsevier; 1 edition (August 17, 2007)
* Language: English
* ISBN-10: 0444520104

Book Description
This volume in the Handbook of Clinical Neurology (Series Editors: Michael J. Aminoff, Department of Neurology, University of California, San Francisco, USA; François Boller, Bethesda, USA; Dick F. Swaab, Netherlands Institute for Neuroscience, Amsterdam, the Netherlands) covers the neurological aspects of HIV/AIDS. The complications of AIDS described include opportunistic infections, central nervous system tumours, spinal cord disorders, peripheral neuropathies and progressive encephalopathy. The advances in molecular biology and the advent of other investigative techniques are described that have transformed the understanding of the basic mechanisms of the disease and the development of therapeutic strategies. Despite the much improved prognosis provided by antiretroviral therapy, the situation is different in the developing world and a chapter highlights the neurological aspects of HIV/AIDS as found there. This volume gives a comprehensive account invaluable both to the clinical neurologist and neuroscience researcher.
* A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology.
* International list of contributors including the leading workers in the field.
* Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.

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Sunday, April 6, 2008

Disease in Wild Animals: Investigation and Management

Disease in Wild Animals: Investigation and Management
by Gary A. Wobeser (Author)

Product Details
* Hardcover: 394 pages
* Publisher: Springer; 2nd ed. edition (April 12, 2007)
* Language: English
* ISBN-10: 3540489746

Book Description
Wildlife diseases have become increasingly important recently due to their effect upon human health, veterinary medicine, wildlife, and conservation biology.
Gary Wobeser's successful book from 1994 has been completely updated and enlarged in a new second edition. An in-depth overview of the available techniques for the investigation and management of disease in free-ranging animals is provided. The subjects are illustrated with examples drawn from around the world, with emphasis on the special requirements involved in working with wild animals. Techniques are assessed critically with regard to their efficacy and effectiveness. The book draws on the authors training as a wildlife biologist and veterinarian and his experience over four decades with wildlife disease.

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Inflammatory Bowel Disease: Crossroads of Microbes, Epithelium and Immune Systems

Inflammatory Bowel Disease: Crossroads of Microbes, Epithelium and Immune Systems
by Novartis Foundation (Author)

Product Details
* Hardcover: 238 pages
* Publisher: Wiley; 1 edition (January 14, 2005)
* Language: English
* ISBN-10: 0470090464

Book Description
Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the exact cause of IBD remains undetermined, the condition appears to be related to a combination of genetic and environmental factors resulting in an aberrant activation of the mucosal immune system. This book contains a series of interdisciplinary discussions between clinical and basic scientists focusing on key issues such as:
* Epithelial cell and molecular biology, including apoptosis, necrosis and cell survival
* The role of bacterial milieu and mucosal bacteria in the IBD and of prebiotic and probiotic therapy
* The progress towards the identification of susceptibility genes and phenotype-determining genes
* The pharmacogenetics of IBD
* Mucosal immunology and therapeutic strategies stemming therefrom

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Saturday, April 5, 2008

Digestive Involvement in Systemic Autoimmune Diseases

Digestive Involvement in Systemic Autoimmune Diseases, Volume 8 (Handbook of Systemic Autoimmune Diseases)
by Manel Ramos-Casals (Editor), Joan Rodes (Editor), Josep Font (Editor), Ronald Asherson (Series Editor)

Product Details
* Hardcover: 350 pages
* Publisher: Elsevier Science; 1 edition (April 16, 2008)
* Language: English
* ISBN-10: 0444531688

Book Description
The book "The digestive system in systemic autoimmune diseases" represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases.
The volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations.
International in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico and South Africa share their knowledge in this detailed volume.
*One book of leading international clinical and scientific experts on autoimmune and digestive diseases.
*A practical guide to the identification, diagnosis and treatment of digestive involvement in patients with autoimmune diseases that will be useful for all medical specialties.
*Several diseases and conditions not included in other text books are included, some of which are of recent emergence.
*Each chapter is designed to serve as a Guide to Clinical Practice for each disease.

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Managing the Laboratory Animal Facility

Managing the Laboratory Animal Facility
by Jerald Silverman (Author)

Product Details
* Hardcover: 216 pages
* Publisher: CRC; 1 edition (October 18, 2001)
* Language: English
* ISBN-10: 0849312337

Book Description
Most people in research are elevated into managerial positions because of their skills as scientists and their political acumen, not necessarily because of managerial training or experience. Helping to fill this need for managerial training, author Jerald Silverman shares the valuable information he's gained from over 25 years experience managing a laboratory animal facility. He takes proven managerial concepts and adapts them to the laboratory animal facility setting. Whether you are a manager in training or you are looking for help in applying the basic concepts of managing a laboratory animal facility, this book helps you fulfill the unique responsibilities of assessing needs, communicating effectively, and establishing goals with people from many different academic and skill levels.

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Friday, April 4, 2008

Laboratory Biosecurity Handbook

Laboratory Biosecurity Handbook
by Reynolds M. Salerno (Author), Jennifer Gaudioso (Author)

Product Details
* Hardcover: 208 pages
* Publisher: CRC; 1 edition (June 21, 2007)
* Language: English
* ISBN-10: 0849364752

Book Description
In recognition of the vital need to protect legitimate facilities from the theft and misuse of dangerous pathogens and toxins, the Laboratory Biosecurity Handbook serves as a guide to the implementation of pathogen protection programs. The first sections of the book offer an historical overview of biological weapons activity, key principles of biosecurity and its integration into existing frameworks, as well as a discussion of biosecurity risk. Later sections discuss biosecurity risk assessments, describe detailed components of a biosecurity program, and offer a graded approach to biosecurity through multiple risk levels. The work also covers risk prioritization of biological assets and biosecurity training.

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Handbook of Chemical and Biological Warfare Agents

Handbook of Chemical and Biological Warfare Agents, Second Edition
by D. Hank Ellison (Author)

Product Details
* Hardcover: 800 pages
* Publisher: CRC; 2 edition (August 24, 2007)
* Language: English
* ISBN-10: 0849314348

Book Description
Extensively revised and updated, this second edition of the bestselling Handbook of Chemical and Biological Warfare Agents goes well beyond the dirty thirty commonly discussed agents and provides rapid access to a wide range of agents that can be used as weapons. This edition incorporates additional classes of agents, expands existing classes, and increases the number of agents described. Expanding the scope of the original, this edition is rich with scientific data and provides more information on the chemical, physical, and biological properties of these agents and their health effects.
Highly organized and cross-referenced to provide instant access to the most authoritative data, this handbook is divided into classes based on the common military groupings of chemical, biological, and toxin agents. Additional classes are provided where the divisions are too broad for appropriate identification, along with classes for non-traditional agents and improvised industrial materials. At the end of each class section is detailed technical information about individual agents, components, precursors, and decomposition products within that class.
Employing four indices along with the handbooks own identification number, each entry follows a standard format for that class including toxicology, characteristics, hazards, protection, and medical response. Other information is provided where applicable such as chemical formula, routes of exposure, medicinal uses, threat or treaty listing, and descriptions of the disease as it appears in humans, animals, and plants. All values are based on a standard man model to allow for consistency of data and evaluations.
Still the gold-standard reference in the field, Handbook of Chemical and Biological Warfare Agents, Second Edition raises the bar in terms of both quality and quantity and assures accuracy across the widest variety of military, scientific, and medical sources available.

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Neutrophil Methods and Protocols

Neutrophil Methods and Protocols (Methods in Molecular Biology)
by Mark T. Quinn (Editor), Frank R. DeLeo (Editor), Gary M. Bokoch (Editor)

Product Details
* Hardcover: 629 pages
* Publisher: Humana Press; 1 edition (August 2, 2007)
* Language: English
* ISBN-10: 1588297888

Book Description
Neutrophil Methods and Protocols provides a concise set of protocols for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step-by-step diagnostic assays of common neutrophil disorders. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Parts 1 & 2 provide an overview of neutrophils the methods most commonly used for isolating them from humans and other animal species. Part 3 details methods for investigating adhesion, chemotaxis, phagocytosis and bacterial activity. Part 4 presents protocols measuring gene expression in neutrophils, and Part 5 concludes with assays for diagnosing the most common neutrophil disorders. Both basic scientists and clinicians will find a collection of this caliber to be an invaluable aid in their work with neutrophils.

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Thursday, April 3, 2008

The Official Patient's Sourcebook on Ascariasis

The Official Patient's Sourcebook on Ascariasis: A Revised and Updated Directory for the Internet Age
by Icon Health Publications (Author)

Product Details
* Paperback: 136 pages
* Publisher: Icon Health Publications (September 2002)
* Language: English
* ISBN-10: 0597833621

Book Description
This book has been created for patients who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells patients where and how to look for information covering virtually all topics related to ascariasis (also ascarid infection; ascarids ), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on ascariasis. Given patients' increasing sophistication in using the Internet, abundant references to reliable Internet-based resources are provided throughout this sourcebook. Where possible, guidance is provided on how to obtain free-of-charge, primary research results as well as more detailed information via the Internet. E-book and electronic versions of this sourcebook are fully interactive with each of the Internet sites mentioned (clicking on a hyperlink automatically opens your browser to the site indicated). Hard-copy users of this sourcebook can type cited Web addresses directly into their browsers to obtain access to the corresponding sites. In addition to extensive references accessible via the Internet, chapters include glossaries of technical or uncommon terms.

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Sexually Transmitted Diseases: A Practical Guide for Primary Care

Sexually Transmitted Diseases: A Practical Guide for Primary Care (Current Clinical Practice)
by Anita L. Nelson (Editor), Jo Ann Woodward (Editor)

Product Details
* Hardcover: 358 pages
* Publisher: Humana Press; 1 edition (June 6, 2007)
* Language: English
* ISBN-10: 1588295702

Book Description
Sexually Transmitted Diseases: A Practical Guide for Primary Care covers the diagnosis and treatment of STDs and other information critical to patient care in the new millennium. This collaboration provides the clinician with the ability to identify and manage Sexually Transmitted Infections (STIs), as well as obtain information about preventing their sequelae.
Among the topics covered in this book are human papillomavirus and genital warts, genital herpes, viral hepatitis, HIV infection and AIDS, chlamydial and gonorrheal infections, and upper genital tract infections in women. Other topics of interest include syphilis, trichomoniasis, chancroid, granuloma inguinale, lymphogranuloma venereum, and molluscum contagiosum. Special consideration is given to ectoparasites, patient-clinician communication and STD care, cultural competence and STI care, effectiveness of barrier methods for STI prevention, and the future role of vaccines and microbides.
Written by clinicians, many of whom have been diagnosing, treating, and counseling patents since the days of venereal disease, this book is packed with evidence-based information steeped in these clinicians' years of practice.

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Allogeneic Immunotherapy for Malignant Diseases

Allogeneic Immunotherapy for Malignant Diseases (Basic and Clinical Oncology)
by Barrett/Jiang (Author)

Product Details
* Hardcover: 387 pages
* Publisher: Informa Healthcare; 1st edition (February 15, 2000)
* Language: English
* ISBN-10: 0824767810

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Superantigens and Superallergens

Superantigens and Superallergens (Chemical Immunology)
by G. Marone (Editor)

Product Details
* Hardcover: 243 pages
* Publisher: S. Karger AG (Switzerland); 1 edition (April 30, 2007)
* Language: English
* ISBN-10: 3805582668

Book Description
The latest advances at molecular and biochemical levels Superantigens constitute a growing family of bacterial and viral proteins that share the capacity of inducing massive activation of the immune system. This volume contains contributions from leaders in the field of classical T cell superantigens and sheds light on relevant B cell superantigens at the molecular and biochemical levels. Moreover, articles in this publication deal with the emerging, intriguing possibility that immunoglobulin superantigens can activate primary effector cells of allergic disorders both in vitro and in vivo, thus acting as superallergens. A detailed account is also given of the biochemical, immunological and clinical characteristics of several endogenous, viral and bacterial superallergens, which are probably relevant in a variety of human diseases. This is the first volume to put together basic and clinical aspects of the classical T cell superantigens, B cell superantigens and superallergens. It will therefore be indispensable reading to basic and clinical immunologists, microbiologists, virologists and specialists in allergic and immune disorders.

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Wednesday, April 2, 2008

Practical Fermentation Technology

Practical Fermentation Technology
by Brian McNeil (Editor), Linda Harvey (Editor)

Product Details
* Hardcover: 402 pages
* Publisher: Wiley (April 4, 2008)
* Language: English
* ISBN-10: 0470014342

Book Description
A hands-on book which begins by setting the context;- defining 'fermentation' and the possible uses of fermenters, and setting the scope for the book. It then proceeds in a methodical manner to cover the equipment for research scale fermentation labs, the different types of fermenters available, their uses and modes of operation. Once the lab is equipped, the issues of fermentation media, preservation strains and strain improvement strategies are documented, along with the use of mathematical modelling as a method for prediction and control. Broader questions such as scale-up and scale down, process monitoring and data logging and acquisition are discussed before separate chapters on animal cell culture systems and plant cell culture systems. The final chapter documents the way forward for fermenters and how they can be used for non-manufacturing purposes. A glossary of terms at the back of the book (along with a subject index) will prove invaluable for quick reference.Edited by academic consultants who have years of experience in fermentation technology, each chapter is authored by experts from both industry and academia. Industry authors come from GSK (UK), DSM (Netherlands), Eli Lilly (USA) and Broadley James (UK-USA).

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Atlas Effectors of Anti-Tumor Immunity

Atlas Effectors of Anti-Tumor Immunity
by Mikhail V. Kiselevsky (Editor)

Product Details
* Hardcover: 270 pages
* Publisher: Springer; 1 edition (April 2008)
* Language: English
* ISBN-10: 1402069308

Book Description
The Atlas Effectors of Anti-Tumor Immunity is a unique scientific publication, which includes major issues of up-to-date information about immunophenotype, morphology and function of main effectors of anti-tumor immunity presented in a reasonable format. The Atlas comprises a large number of illustrations presented by schemes and original micrographs demonstrating morphological features and ultrastructure of immunocompetent cells at various stages of differentiation. The volume includes data referring to the history of anti-tumor immunity effectors research, state of the art and perspectives for development of anti-cancer adoptive immunotherapy methods.
A special section of the Atlas describes cellular tumor microenvironment and micro-anatomy of carcinomas. Several parts include data about killer cells (natural killer T-cells, lymphokine-activated killers) and T-regulatory lymphocytes. A special chapter gives a wide-range description of antigen-presenting dendritic cells, methods of dendritic cell generation and development of DC-based vaccines for anti-tumor immunotherapy.
Co-authors of this book are expert scientists of major research centers of the USA and Europe, Atlas contents involves literature data analysis and results of long-term experimental and clinical studies. Atlas may be recommended as an additional study guide for medical and biology students and it may be interesting to experimental and clinical oncologists, immunologists, specialists of research and diagnostic centers.


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Tuesday, April 1, 2008

New Antibiotic Targets

New Antibiotic Targets (Methods in Molecular Medicine)
By W. Scott Champney

Product Details
* Hardcover: 296 pages
* Publisher: Humana Press; 1 edition (January 15, 2008)
* Language: English
* ISBN-10: 1588299155

Book Description
A crisis is developing in the treatment of infectious diseases, with microorganisms frequently showing resistance to currently prescribed antibiotics. Fewer and fewer antimicrobial agents are now available to treat these infections. In New Antibiotic Targets, W. Scott Champney examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. By testing new antimicrobial agents and modified existing drugs, the most vulnerable cell processes, such as cell wall and membrane synthesis, DNA replication, RNA transcription and protein synthesis, can be better exploited. This in-depth volume, however, delves even deeper by identifying additional novel cellular targets for these new therapies.
New Antibiotic Targets provides laboratory investigators with the vital tools they need to test the antimicrobial potential of products and to curb the rise of so many infectious diseases.

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Handbook of Human Immunology

Handbook of Human Immunology, Second Edition
by Maurice R.G. O'Gorman (Editor), Albert D. Donnenberg (Editor)

Product Details
* Hardcover: 640 pages
* Publisher: CRC; 2 edition (February 15, 2008)
* Language: English
* ISBN-10: 0849319846

Book Description
Since the publication of the first edition of the Handbook of Human Immunology in 1997, major scientific achievements have elucidated our understanding of the complexities of the human immune system. This second edition compiles the major breakthroughs of the past decade including dramatic increases in the number of recognized clusters of differentiation on the surface of leukocytes and associated cells, establishment of an entire new chemokine and chemokine receptor nomenclature system, and discovery of more than 30 lymphokines. The text emphasizes clinically relevant immunological parameters, and clarifies the basic principles underlying immune system assays, as well as applications and interpretations of immune tests.

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