The World of Rhabdoviruses

The World of Rhabdoviruses (Current Topics in Microbiology and Immunology)
by Z.F. Fu (Editor)

Product Details:
* Hardcover: 208 pages
* Publisher: Springer; 1 edition (December 31, 1899)
* Language: English
* ISBN-10: 354024011X

Book Description
Rhabdoviruses have a very wide host range and have been isolated from plants, insects, and almost from all vertebrates including fish and primates. The Rhabdoviridae family consists of six genera which have all been associated with diseases. While rhabdoviruses that are etiological agents of human diseases can cause serious public health problems, other members of this family that infect domestic livestock and agricultural plants can also cause enormous economic loss.

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Pseudomonas

Pseudomonas: Volume 4: Molecular Biology of Emerging Issues
by Juan-Luis Ramos (Editor), Roger C. Levesque (Editor)

Product Details:
* Hardcover: 367 pages
* Publisher: Springer; 1 edition (June 2, 2006)
* Language: English
* ISBN-10: 0387288341

Book Description:
The first three volumes of the Pseudomonas series covered the biology of pseudomonads in a wide context, including the niches they inhabit, the taxonomic relations among members of this group, the molecular biology of gene expression in different niches and under different environmental conditions, the analysis of virulence traits in plants, animals and human pathogens as well as the determinants that make some strains useful for biotechnological applications and promotion of plant growth.
Pseudomonas volume 4 is intended to collect some of the most relevant new emerging issues in the field of Pseudomonas that were not assembled in the three previous volumes.
This fourth volume covers the following topics:
- Virulence and Pathogens
- Genomics and Proteomics
- Physiology, Metabolism and Biotechnology
Pseudomonas volume 4 will be of use to researchers working on these bacteria, particularly those studying virulence, genomics, physiology, biotechnology, etc. Advanced students in biology, medicine and agronomy will also find this volume a valuable reference during their studies.

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Neurovirology : Viruses and the Brain

Neurovirology : Viruses and the Brain (Advances in Virus Research, Volume 56) (Advances in Virus Research)
by Michael Buchmeier (Editor), Ian Campbell (Editor)

Product Details:
* Hardcover: 645 pages
* Publisher: Academic Press (August 4, 2006)
* Language: English
* ISBN-10: 0120398567

Book Description:
"This serial...is well known to virologists. It is a valuable aid in maintaining an overview of various facets of the rapidly expanding fields of virology.... Timely, informative, and useful to the student, teacher, and research scientist." - American Scientist
"A mandatory purchase for all types of comprehensive libraries, both public and university, as well as for those interested in or doing research in the field of virology." - Military Medicine

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Advances in Virus Research, Volume 69

Advances in Virus Research, Volume 69 (Advances in Virus Research) (Advances in Virus Research)
by Karl Maramorosch (Series Editor), Aaron J. Shatkin (Series Editor)

Product Details:
* Hardcover: 328 pages
* Publisher: Academic Press (January 17, 2007)
* Language: English
* ISBN-10: 0123737125

Book Description
Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology.
In 2004, the Institute for Scientific Information released figures showing that the series has an Impact Factor of 2.576, with a half-life of 7.1 years, placing it 11th in the highly competitive category of Virology.

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Allergy: An Atlas of Investigation and Management

Allergy: An Atlas of Investigation and Management
by S.H. Arshad (Editor), S.T. Holgate (Editor), N.F. Adkinson (Editor), K. S. Babu (Editor)

Product Details:
* Hardcover: 120 pages
* Publisher: Informa Healthcare (July 19, 2005)
* Language: English
* ISBN-10: 1904392245

Book Description:
In one form or another, allergies and intolerances affect approximately one third of the population, with as many as half of all sufferers being children. An illustrated guide, Allergy, An Atlas of Investigation and Diagnosis demystifies the whole subject. This exciting new reference is designed with one purpose - to help allergy specialists and the general practitioners care for patients with allergic disorders and improve the standard of care they provide. In a highly-illustrated, easy-to-follow format, this book supplies the ready-to-use information needed for the diagnosis and treatment of allergic diseases.

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Coronavirus Replication and Reverse Genetics

Coronavirus Replication and Reverse Genetics (Current Topics in Microbiology and Immunology)
by Luis Enjuanes (Editor)

Product Details:
* Hardcover: 257 pages
* Publisher: Springer; 1 edition (November 23, 2004)
* Language: English
* ISBN-10: 3540214941

Book Description:
Until the late 1960s, the coronaviruses were not recognized as pathogens responsible for human diseases (common cold). However, in 2003 human coronaviruses (HCoVs) came to worldwide attention with the emergence of the Severe and Acute Respiratory Syndrome (SARS), produced by a coronavirus (SARS-CoV) that infected more than 8000 people, killing about ten percent of them in 32 countries. The increase in research on coronaviruses soon led to the discovery of another human coronavirus (HCoV-NL63) which is prevalent in 7% of hospital patients and has been associated with bronchiolitis and, possibly, conjunctivitis.

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Role of Apoptosis in Infection

Role of Apoptosis in Infection (Current Topics in Microbiology and Immunology)
by Diane Griffin (Editor)

Product Details:
* Hardcover: 294 pages
* Publisher: Springer; 1 edition (May 25, 2005)
* Language: English
* ISBN-10: 3540230068

Book Description:
This mechanism of programmed cell death plays an important role in normal development and control of cell numbers in mature animals. Initiation of the apoptotic process can come from external or internal stimuli and is highly regulated both by molecules that facilitate and by molecules that inhibit the process. It can be envisioned that apoptosis as a response to an intracellular pathogen is a useful way for the host to eliminate infected cells, decreasing the likelihood of spread of the infection to neighboring cells and preventing pathogen persistence. Alternatively, the apoptotic response may be a major mechanism by which the host is harmed by a pathogen.

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CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential

CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential (Current Topics in Microbiology and Immunology)
by B. Kyewski (Editor), Elisabeth Suri-Payer (Editor)

Product Details
* Hardcover: 330 pages
* Publisher: Springer; 1 edition (July 21, 2005)
* Language: English
* ISBN-10: 3540244441

Book Description
The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body's own constituents thus preserving its integrity. Multiple mechanisms act in concert to ensure self-tolerance. Additional tolerance mechanisms, collectively referred to as dominant tolerance is by now firmly established. It will offer new conceptual insights and hopefully new tools for the sucessful treatment of autoimmune diseases, improved cancer immunotherapy and transplant survival.

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The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions

The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions
by Roger Garrett (Editor), Stephen R. Douthwaite (Editor), Anders Liljas (Editor), Alistair T. Matheson (Editor), Peter B. Moore (Editor), Harry F. Noller (Editor), Roger A. Garrett (Author), Anders Lilgas (Author), Harry F. Noler (Author)

Product Details:
* Hardcover: 565 pages
* Publisher: ASM Press; 2Rev Ed edition (June 15, 2000)
* Language: English
* ISBN-10: 1555811841

Book Description:
This new four-color edition of this important reference summarizes the major advances that have occurred over the past five years in our undersatnding of the ribosome and protein synthesis. It offers the first detailed account of crystal structures of the ribosome as well as insights into the mechanisms and action of antibiotics. The structure and function of numerous extra-chromosomal factors are also examined.

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Immunobiology of Natural Killer Cell Receptors

Immunobiology of Natural Killer Cell Receptors (Current Topics in Microbiology and Immunology)
by Eric Vivier (Editor), Marco Colonna (Editor)

Product Details:
* Hardcover: 286 pages
* Publisher: Springer; 1 edition (December 1, 2005)
* Language: English
* ISBN-10: 3540260838

Book Description:
Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.

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Handbook of Topical Antimicrobials

Handbook of Topical Antimicrobials: Industrial Applications in Consumer Products and Pharmaceuticals
by Daryl S. Paulson (Author)

Product Details:
* Hardcover: 464 pages
* Publisher: CRC (September 19, 2002)
* Language: English
* ISBN-10: 0824707885

Book Description:
This reference examines laboratory techniques and FDA and industry perspectives on medical, food service, and consumer product applications of antimicrobials. It offers methods to conduct investigations of effectiveness that simulate use of consumer, food, and medical antimicrobials in real-world conditions and environments, validate neutralizing systems, develop reliable and functional antimicrobial products, and prevent infection, disease, and contamination. Additional topics include the importance of customer-valued quality attributes, such as low skin irritation and ease of use, label claims, regulatory procedures, and quality control, and clinical simulation protocols.

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Brucella: Molecular and Cellular Biology

Brucella: Molecular and Cellular Biology
by I. Lopez-Goni (Author)

Product Details:
* Hardcover: 432 pages
* Publisher: Taylor & Francis; 1 edition (January 13, 2005)
* Language: English
* ISBN-10: 1904933041

Book Description
Horizon Scientific Press titles focus on high-level microbiology and molecular biology topics. Written by internationally renowned and highly respected leaders in the field, they comprise of review manuals, practical manuals, and reference texts for research scientists, bioscience professionals and graduate students.
Publication of the complete genome sequences of several different Brucella species has provided researchers with the opportunity to take a more directed approach to study this organism's physiology, virulence, and genetic diversity. In this book highly acclaimed Brucella scientists comprehensively review all of the most important advances in the Brucella post-genomic era providing for the first time a coherent picture of Brucella molecular and cellular biology.
The book opens with chapters that focus on the development of molecular diagnostic tools followed by chapters on genetic evolution and its relationship to pathogenicity. Other topics include Brucella comparative genomics and proteomics, analysis of the structure, biosynthesis and biology of glucans and lipopolysaccharides, pathogenicity, approaches to vaccine development, bacterium-host interactions, immune response, and much more. Essential reading for everyone with an interest in Brucella and brucellosis and recommended reading for the wider body of scientists with an interest in microbial diagnostics, microbial pathogenesis, cellular microbiology and immunology, and vaccine development.

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Clinical Approach to Infection in the Compromised Host

Clinical Approach to Infection in the Compromised Host
by Robert H. Rubin (Editor), Lowell S. Young (Editor)

Product Details:
* Hardcover: 1000 pages
* Publisher: Springer; 4 edition (June 15, 2002)
* Language: English
* ISBN-10: 0306466937

Book Description
This highly anticipated Fourth Edition of a well-regarded resource offers in-depth examinations of the latest developments in the management of infections in the immuno-compromised patient.
Addressing the explosion of research information and clinical approaches that have emerged since the publication of the third edition, world-renowned experts maintain and enhance the lucid and accessible presentations that made the previous editions so popular.
Covering every important aspect of compromised-host infection, this Fourth Edition offers several new features, including:
-discussions on infections that result from hematopoietic stem cell transplantation;
-the most recent developments in the management and prevention of infection in immunocompromised surgical patients;
-a detailed discussion of the management of AIDS;
-up-to-date, critical reviews of the current literature;
-practical management advice incorporating the latest scientific information;
-a variety of perspectives that clarify complex patients care issues faced by the practitioner;
-and much more.

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Molecular Biology and Pathogenicity of Mycoplasmas

Molecular Biology and Pathogenicity of Mycoplasmas
by Shmuel Razin (Editor), Richard Herrmann (Editor)

Product Details:
* Hardcover: 588 pages
* Publisher: Springer; 1 edition (May 1, 2002)
* Language: English
* ISBN-10: 0306472872

Book Description
The recent sequencing of mycoplasma genomes has marked a turning point in the molecular genetic analysis of these microorganisms. Transcriptome and proteome analyses promise to provide the first definition of the total protein complement of a cell. The mycoplasma group includes the smallest known self-replicating organisms carrying the smallest number of genes. No wonder, therefore, that mycoplasmas have a special appeal to those interested in deciphering the minimal set of genes essential for life. Mycoplasma genomics facilitated better understanding of mycoplasma pathogenesis. Most impressive are the findings concerning the interaction of mycoplasmas with the immune system, macrophage activation, cytokine induction, mycoplasma cell components acting as superantigens, and autoimmune manifestations. The molecular definition of mycoplasmal adhesins responsible for mycoplasma attachment to host cells and evasion of the host immune system by antigenic variation of mycoplasmal surface components are other `hot' subjects of research. Demonstration of the ability of mycoplasmas to enter host cells, cause fusogenic, apoptotic and oncogenic effects, as well as the possible association of mycoplasmas with arthritis, had their share in intensifying research on mycoplasma pathogenesis, bringing more researchers into the circle of those interested in this group of organisms. The present book is a comprehensive, up-to-date, multi-authored treatise.

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Killer Lymphocytes

Killer Lymphocytes
by Gideon Berke (Author), William R. Clark (Author)

Product Details:
* Hardcover: 361 pages
* Publisher: Springer; 1 edition (December 31, 1899)
* Language: English
* ISBN-10: 1402032692

Book Description:
We have known about the existence of killer lymphocytes since 1960, when they were discovered in connection with transplant rejection in vivo. Since then we have uncovered at least five subsets of lymphocytes that can kill other cells in vitro, establishing the study of cell-mediated cytotoxicity (CMC) as a major field of immunological inquiry. Berke and Clark summarize the extensive literature based on the study of CMC in vitro. Several important questions about killer cells have now been answered, for example, how they go about destroying other cells. Research ultimately revealed at least three lytic mechanisms available to killer lymphocytes. But do killer cells actually use these mechanisms in vivo? The possible involvement of CMC in transplant rejection, control of intracellular parasites, cancer, autoimmunity, and immune homeostatic regulation is analyzed in detail, yielding some surprising findings, and outlining important questions that remain unanswered.

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Re-emergence of Established Pathogens in the 21st Century

Re-emergence of Established Pathogens in the 21st Century
by I.W. Fong (Editor), Karl Drlica (Editor)

Product Details:
* Hardcover: 312 pages
* Publisher: Springer; 1 edition (June 2003)
* Language: English
* ISBN-10: 0306475006

Book Description:
This volume, compiled by two of the leading experts in the field, provides the specialist and trainee in microbiology, infectious disease, infection control, and epidemiology with a concise, timely and authoritative review of some of the most problematic infections of the new century. This volume will foster a better understanding of the issues and new ideas for preventing and controlling infectious disease.
The steady and often alarming rate at which new and reemerging pathogens are appearing is well recognized. The past year alone saw a global epidemic caused by a previously unrecognized coronavirus, the first outbreak of monkeypox in the Western Hemisphere, the continued spread of West Nile virus across North America, the detection of the first U.S. case of mad cow disease, outbreaks of deadly H5N1 avian influenza with transmission to humans in Asia, and the first U.S. outbreak of a highly pathogenic strain of avian influenza in 20 years. Adding to the concern caused by these events is the increasing emergence of antimicrobial resistance in community and health care settings. This topic is the principal focus of Reemergence of Established Pathogens in the 21st Century, the third volume in the series Emerging Infectious Diseases of the 21st Century. The book contains nine authoritative chapters by 21 authors from North America and Europe, many of whom are internationally recognized experts on their topics. The chapters are organized into three sections that are titled "The Changing Spectrum of Bacterial Infections," "Resistant Bacteria and Resurgence," and "Resistant Parasitic Infections." The two initial chapters focus on severe invasive group A streptococcal infections and the broad array of zoonotic bartonella infections recognized in recent years (e.g., cat scratch disease, bacillary angiomatosis, and peliosis hepatis). Other chapters discuss important drug-resistant infections in the community (e.g., leading global killers such as pneumococcal disease, tuberculosis, and malaria) -- a crisis in many impoverished countries -- and drug-resistant infections in health care settings (e.g., methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and multidrug-resistant Enterobacteriaceae). In addition to providing a helpful historical context for the problem, each chapter contains information on the epidemiology and microbiology of the infection (including considerable detail on mechanisms of resistance), along with information on clinical features, diagnosis, treatment, and prevention strategies. Most chapters end with a brief discussion of factors contributing to the disease's emergence or reemergence as well as priorities for research. Each chapter is well documented, with extensive references through early 2002. One chapter contains a provocative discussion of an approach to controlling antimicrobial resistance on the basis of the "mutant selection window" hypothesis and possible approaches to reducing the risk of mutant enrichment. Overall, the chapters provide important information to the intended target audience of specialists and trainees in microbiology, infectious diseases, infection control, and epidemiology. The book makes good use of tables and figures to convey important information clearly. In addition, some of the diagrams of pathogenetic and resistance mechanisms are particularly helpful. The use of color in the histopathological images in the chapter on bartonella would have added value; however, the price of the book is already somewhat high. The problem of emerging microbial infections and the urgent need to address these threats were brought to the forefront of public health in a 1992 report by the Institute of Medicine and were the subject of a 2003 update to this report entitled Microbial Threats to Health: Emergence, Detection, and Response. This book reinforces the findings in those two reports and reminds the reader of the many factors in contemporary society that favor the continued emergence and reemergence of infectious diseases. The authors highlight the need to refocus the efforts of the clinical, research, and public health communities to improve disease surveillance and develop sensitive, specific, and rapid diagnostic tests, as well as to prescribe antimicrobial agents judiciously and continue work to develop the next generation of vaccines and antimicrobial agents.

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Antigenic Variation

Antigenic Variation
by Alister G. Craig (Editor), Artur Scherf (Editor)

Product Details:
* Hardcover: 464 pages
* Publisher: Academic Press (September 24, 2003)
* Language: English
* ISBN-10: 012194851X

Book Description
The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body.
The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour.

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Hepatitis B and D Protocols

Hepatitis B and D Protocols: Volume 2: Immunology, Model Systems, and Clinical Studies (Methods in Molecular Medicine)
by Robert K. Hamatake (Editor), Johnson Y. N. Lau (Editor)

Book Description
A broad-ranging collection of cutting-edge techniques for the study of HBV and HDV infections and for the development of therapies to treat them. In this second of two volumes, Immunology, Model Systems, and Clinical Studies, the authors focus on protocols for the study of host immune responses to infection, in vitro and in vivo models of infection, and the development of antivirals. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle underlying the technique, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. An accompanying first volume, Detection, Genotypes, and Characterization, contains user-friendly protocols for the identification and quantification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle.

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Introduction To Immunotoxicology

Introduction To Immunotoxicology
by Jacques Descotes (Author)

Product Details:
* Paperback: 250 pages
* Publisher: CRC (December 9, 1998)
* Language: English
* ISBN-10: 0748403078

Book Description:
This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of Major Immunotoxicants. The Second Part Describes The Latest Methods Used to detect and evaluate, preclinically and clinically, the unexpected Immunotoxic Effects Of Xenobiotics. Trends In Implementing Strategies And recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro Methods, Biomarkers Of Immunotixicity And Risk Assessment.

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Handbook of Fungal Biotechnology

Handbook of Fungal Biotechnology, 2nd Edition, Revised and Expanded (Mycology, 20)
by Dilip K. Arora (Editor)

Product Details:
* Hardcover: 600 pages
* Publisher: Marcel Dekker; 2 edition (December 2003)
* Language: English
* ISBN-10: 0824740181

Book Description:
The Handbook of Fungal Biotechnology offers the newest developments from the frontiers of fungal biochemical and molecular processes and industrial and semi-industrial applications of fungi. This second edition highlights the need for the integration of a number of scientific disciplines and technologies in modern fungal biotechnology and reigns as the top source on current molecular, biochemical, and medical technologies and commercial usages for fungi. Authored by 81 world-renowned scientists from both industry and academia, it addresses contemporary issues pertaining to intellectual property rights, biodiversity, and biosafety, and devotes an entire section to medical biotechnology.

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Sinusitis: From Microbiology To Management

Sinusitis: From Microbiology To Management (Infectious Disease and Therapy)
by Itzhak Brook (Editor)

Product Details:
* Hardcover: 496 pages
* Publisher: Informa Healthcare (September 15, 2005)
* Language: English
* ISBN-10: 082472948X

Book Description:
Filling a gap in the literature, this reference provides concise and practical guidelines for the diagnosis and management of sinusitis and furnishes an authoritative outline of our current understanding of the pathophysiology of this condition. Addressing a wide spectrum of issues related to the identification, epidemiology, and etiology of sinusitis, this guide presents detailed illustrations and flowcharts to clarify the interactions between the pathological and physiological processes of sinusitis and illustrate current treatment practices.

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Microbial Protein Toxins

Microbial Protein Toxins (Topics in Current Genetics)
by Manfred J. Schmitt (Editor), Raffael Schaffrath (Editor)

Product Details:
* Hardcover: 237 pages
* Publisher: Springer; 1 edition (February 24, 2005)
* Language: English
* ISBN-10: 3540235620

Book Description
Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably „intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components.
This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.

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Fundamental Virology

Fundamental Virology
by David M Knipe (Author), Peter M Howley (Author)

Product Details:
* Hardcover: 1408 pages
* Publisher: Lippincott Williams & Wilkins; 4th edition (August 15, 2001)
* Language: English
* ISBN-10: 0781718333

Book Description:
Designed for graduate students and researchers in all biological and biomedical sciences, this volume brings together the basic science chapters from the two-volume Fourth Edition of Fields Virology. These 37 chapters comprise a comprehensive text and reference on the concepts and research techniques of contemporary virology and the biochemistry, molecular biology, and replication of all viruses. The first part of the book covers basic concepts of general virology and the second part focuses on specific virus families.

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Practical Molecular Virology

Practical Molecular Virology (Methods in Molecular Biology)
by Mary K. Collins (Author)

Product Details:
* Paperback: 352 pages
* Publisher: Humana Press; 1 edition (October 31, 1991)
* Language: English
* ISBN-10: 089603299X

Book Description
Mary K. L. Collins has assembled in Practical Molecular Virology a vanguard collection of readily repeatable methods for gene transfer and expression using a variety of recombinant viral vectors. In keeping with the established tradition of the series, each technique is presented in an easy-to-follow format designed to work for the novice as well as the seasoned expert. Chapters cover: • life cycles of specific retroviruses and how recombinant vectors are constructed • PCR techniques • poliovirus vectors • herpesvirus vectors • syncytial assays • cell lineage studies • baculovirus and adenovirus vectors • SV40 and EBV vectors • viruses in gene transfer to eukaryotic cells. The wealth of material devoted to recombinant retroviral methods and their applications make Practical Molecular Virology and extremely timely volume, one that will find widespread use throughout biological and biomedical research.

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Encyclopedia of Virology

Encyclopedia of Virology, 3-Volume Set (Allan Granoff & Robert G. Webster)
by Allan Granoff (Editor), Robert G. Webster (Editor)

Product Details:
* Hardcover: 2000 pages
* Publisher: Academic Press; 2 edition (August 20, 1999)
* Language: English
* ISBN-10: 0122270304

Book Description:
The editors and the over 250 expert contributors to this encyclopedia are to be commended for the fantastic work they have done in producing a resource that is valuable to both undergraduates and specialists. The encyclopedia features 270 alphabetically arranged articles discussing topics that range from specific viruses and virus groups to diagnostic techniques and the history of virology. Animal, insect, plant, and bacteriologial viruses are all covered. Each entry includes a self-contained summary of the topic at hand and provides both recommendations for further reading and a list of other relevant entries. Many of the articles have a section on future perspectives that shows the direction of current research. In addition, there are cross references and an extensive index. While expensive, this encyclopedia is the only comprehensive work on virology to have appeared in the past few years. The field is changing so quickly that finding concise, understandable information in a single source is difficult. Other current works include Bernard Fields's Fields Virology (Raven, 1990. 2d ed.) and Fundamental Virology (Raven, 1991). (Fields is a contributor to this volume as well.) These are both textbooks aimed at educating the virologist or physician, while the encyclopedia is geared toward a wider audience. Recommended for academic and medical libraries.

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Difco Manual : Manual of Microbiological Culture Media

Difco Manual : Manual of Microbiological Culture Media

Book descriptions:
This edition of the DIFCO MANUAL, the eleventh published since 1927, has been extensively revised and rewritten. The purpose of the Manual is to provide information about products used in microbiology. The Manual has never been intended to replace any official compendium or the many excellent standard text books of scientific organizations or individual authors.
Difco is perhaps best known as the pioneer in bacteriological culture media. Numerous times one will find the trademarks Difco® or Bacto® preceding the names of materials used by scientists in their published papers. Because Difco products have been readily available worldwide longer than any others, Difco products have become the common-language reagents of the microbiological community. Standardized products readily available worldwide are essential for corroborative studies demanded by rigorous science.
Recommendation and approval have been extended to our products by the authors of many standard text books and by the committees on methods and procedures of scientific societies throughout the world. Difco products continue to be prepared according to applicable standards or accepted formulae. It is expected that they will be used only by or under the supervision of microbiologists or other professionals qualified by
training and experience to handle pathogenic microorganisms. Further, it is expected that the user will be throughly familiar with the intended uses of the formulations and will follow the test procedures outlined in the applicable official compendia and standard text books or procedures manual of the using laboratory.

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Role of gut bacteria in human toxicology and pharmacology

Role of gut bacteria in human toxicology and pharmacology
by Bradley Hillman (Author)

Product Details:
* Hardcover: 286 pages
* Publisher: CRC (April 27, 1995)
* Language: English
* ISBN-10: 0748401105

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Understanding Pathogen Behaviour: Virulence, Stress Response, and Resistance

Understanding Pathogen Behaviour: Virulence, Stress Response, and Resistance (Woodhead Publishing in Food Science and Technology)
by Mansel Griffiths (Other Contributor)

Product Details:
* Hardcover: 611 pages
* Publisher: CRC Press (January 2005)
* Language: English
* ISBN-10: 1855739534

Book Description:
Pathogens respond dynamically to their environment. Understanding their behaviour is critical both because of evidence of increased resistance to established sanitation and preservation techniques, and because of the increased use of minimal processing technologies which are more vulnerable to the development of resistance. Understanding pathogen behaviour summarises the wealth of recent research and its implications for the food industry.

After two introductory chapters on ways of analysing and modelling pathogens, Part 1 summarises current research on what determines pathogenicity, stress response, adaptation and resistance. Part 2 reviews the behaviour of particular pathogens, reviewing virulence, stress response and resistance mechanisms in such pathogens as Salmonella, E.coli and Campylobacter. The final part of the book assesses how pathogens react and adapt to particular stresses from heat treatment and the effects of low temperature to the use of disinfectants and sanitisers.

With its distinguished editor and international team of contributors, Understanding pathogen behaviour will be a standard reference for the food industry in ensuring food safety.

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Encyclopedia of Immunology

Encyclopedia of Immunology (4-Volume Set)
by Ivan M. Roitt (Editor), Peter J. Delves (Editor)

Product Details:
* Hardcover: 6233 pages
* Publisher: Academic Press; 2 edition (July 15, 1998)
* Language: English
* ISBN-10: 0122267656

Book Description:
With more than 700 expert authors from 22 different countries, the Encyclopedia of Immunology, Second Edition is the largest comprehensive reference source of current immunologicalknowledge available. It provides a broad scope and high level of expertise to the many aspects of the field of immunology and related areas, including microbiology, virology, and parasitology. Arranged into 31 subject areas with extensivecross-referencing and subject indexes in eachvolume, the Encyclopedia is easy-to-use for virtually any researcher, regardless of his or her field. Concise definitions of the subject area also introduce each entry. The SecondEdition includes timely and thorough updates for all articles from the First Edition, more than 60 new entries, a glossary of immunological terms in each volume, a total of 500 figures and tables, and new color platessections.
Initial access to the innovative online version offering extensive hypertext linking and advanced search tools is available to buyers of the print edition. Ongoing access is maintained for a minimum annual fee.
Key Features:
* Four volumes, each containing a subject index
* Approximately 630 different articles
* More than 700 expert contributors from 22 different countries
* Coverage of 31 differentsubject areas
* Concise definitions of the subject to introduce each entry
* Further reading lists at the end of each entry
* Extensive cross-referencing
* Entries arranged in a single A-Z list for easyaccess
* Easy-to-read double-column format
* More than 500 figures to complement the text
* More than 60 new articles
* A glossary of immunological terms in each volume
* A color plate section ineach volume

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Measuring Immunity: Basic Science and Clinical Practice

Measuring Immunity: Basic Science and Clinical Practice
by Michael T. Lotze (Editor), Angus W. Thomson (Editor)

Product Details:
* Hardcover: 736 pages
* Publisher: Academic Press (December 30, 2004)
* Language: English
* ISBN-10: 012455900X

Book Description
Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. Measuring Immunity is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology.

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PCR in Bioanalysis

PCR in Bioanalysis (Methods in Molecular Biology)
by Stephen J Meltzer (Editor)

Product Details:
* Hardcover: 292 pages
* Publisher: Humana Press; 1 edition (January 5, 1998)
* Language: English
* ISBN-10: 0896034976

Book Description:
PCR in Bioanalysis offers powerful PCR-based protocols and assays in actual use or potential use in clinical medicine and commercial biology. The main focus of the book is on the commercial applications of PCR, as opposed to basic research uses. Topics covered include the measurement of hormone levels using PCR, transcription factor isolation, detection of viruses using PCR, detection of tumor contamination of stem cells, evaluation of grafts for tumor cells, and more.
Univ. of Maryland, MD. State-of-the-art for the molecular diagnosis of many specific diseases including: cancer; genetic syndromes; and infectious diseases in humans, plants and animals. Modified-outline format. Halftone illustrations. DNLM: Polymerase Chain Reaction--methods.

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Bacteriophages: Biology and Applications

Bacteriophages: Biology and Applications
by Elizabeth Kutter (Editor), Alexander Sulakvelidze (Editor)

Product Details:
* Hardcover: 528 pages
* Publisher: CRC (December 28, 2004)
* Language: English
* ISBN-10: 0849313368

Book Description:
In response to the emergence of pathogenic bacteria that cannot be treated with current antibiotics, many researchers are revisiting the use of bacteriophages to fight multidrug-resistant bacteria. Bacteriophages: Biology and Applications provides unparalleled, comprehensive information on bacteriophages and their applications in agriculture, human therapy, and biotechnology. It offers techniques, media, and methodology involved in isolating and working with therapeutic phages. Photographs, line drawings, and electron micrographs of phages are also included. With its broad approach, this book is a useful reference for researchers and clinicians from a wide variety of disciplines.

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Models Of Viral Hepatitis

Models Of Viral Hepatitis (Monographs in Virology)
by Fritz Von Weizsacker (Editor), Michael Roggendorf (Editor)

Product Details:
* Hardcover: 164 pages
* Publisher: S. Karger AG (Switzerland) (January 31, 2005)
* Language: English
* ISBN-10: 3805578091

Book Description:
Discusses evolving methods in animal and in vitro models
Viral hepatitis B or C is the most common cause of chronic liver disease worldwide and accounts for about 80% of all hepatocellular carcinoma cases. Thus, combating viral hepatitis remains one of the most pressing public health issues today. Animal models and cell-based systems are essential tools for addressing the many still unresolved basic and clinical problems. Experimental models are needed to better understand the viral life cycles, pathogenetic aspects and natural defense mechanisms, while preclinical models are required for evaluating novel preemptive and therapeutic strategies.
This monograph provides a unique synopsis of currently available models of viral hepatitis, highlighting their particular use for basic and translational science. Leading experts discuss new scientific results and evolving methods in various animal and in vitro models, including the woodchuck, duck, mouse, chimpanzee and tupaia, as well as primary hepatocytes and subgenomic HCV replicons.
A valuable single source of information, this book will be of interest to all investigators and clinicians working in the fields of viral hepatitis and/or hepatology.

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The Laboratory Mouse

The Laboratory Mouse
by Mark A. Suckow (Author), Peggy Danneman (Author), Cory Brayton (Author)

Product Details:
* Plastic Comb: 184 pages
* Publisher: CRC; 1ST edition (December 27, 2000)
* Language: English
* ISBN-10: 0849303222

Book Description:
Laboratory Mouse provides a single source reference for investigators, technicians, and animal caretakers charged with the care and/or use of mice in biomedical research. The book is particularly valuable to researchers at small institutions and to those who work at facilities that lack large, well-organized animal resource units. A complete and concise overview, this book provides instructions for the humane care of laboratory mice. It includes numerous figures that clearly illustrate concepts and offers resources of relevance to laboratory mice and extensive references for further study.

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Bacterial Toxins: Methods and Protocols

Bacterial Toxins: Methods and Protocols (Methods in Molecular Biology)
by Otto Holst (Editor)

Product Details:
* Hardcover: 379 pages
* Publisher: Humana Press; 1 edition (March 15, 2000)
* Language: English
* ISBN-10: 0896036049

Book Description:
Experienced researchers describe in step-by-step detail powerful methods for the investigation of bacterial exo- and endotoxins. These state-of-the-art techniques range from purification and detection methods to methods of conformational analysis, and include the use of phage antibody libraries and methods of structural and functional analyses of endotoxins. Each protocol is described by a scientist who has regularly used the method and optimized it to a high level of performance. Extensive notes deal with the difficulties that may arise when using the method and with the method's limitations and possible modification for other purposes. Cutting-edge and geared to producing successful experimental results, Bacterial Toxins: Methods and Protocols provides investigators with a first-rate collection of readily reproducible methods designed to help today's bacterial toxin investigators-both novice and expert-utilize a wide array of powerful research tools.

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The Allergy and Asthma Cure

The Allergy and Asthma Cure: A Complete Eight-Step Nutritional Program
by Fred M.D. Pescatore (Author), Fred Pescatore (Author)

Product Details:
* Hardcover: 272 pages
* Publisher: Wiley; 1 edition (January 17, 2003)
* Language: English
* ISBN-10: 047121468X

Book Description
Free yourself of allergies and asthma once and for all with Dr. Pescatore’s breakthrough program

" Dr. Fred Pescatore’s The Allergy and Asthma Cure reveals a unique and revolutionary understanding of the underlying conditions of allergy and asthma–from food triggers to the environment to nutritional deficiencies. His integrative program of both alternative and traditional treatments can dramatically improve health and vitality, safely and soundly. This book will have a prominent place in my library and I highly recommend it! "
–Ann Louise Gittleman, Ph.D., C.N.S., author of the bestselling The Fat Flush Plan

"Conventional medicine has largely shrugged its shoulders in confusion about the causes of allergies and asthma in millions of people. In this book Dr. Fred Pescatore deals with the roots of these modern epidemics, drawing on his clinical experience, and he provides clear recommendations for turning back the tide and restoring health."
– Jack Challem, author of the bestselling Syndrome X and The Inflammation Syndrome

"The Allergy and Asthma Cure is the book we have all been waiting for. Dr. Pescatore manages, in a concise manner, to summarize all the facts and presents a comprehensive healing guide that incorporates both conventional and alternative approaches. A must-read for those dealing with these issues."
–Artur Spokojny, M.D., F.A.C.C., Medical Director of Integrative Medicine of Manhattan, Associate Professor of Medicine, Weill Cornell Medical College

"I believe that The Allergy and Asthma Cure holds the key to understanding how nutritional medicine can really work for you. Allergies (from skin conditions to seasonal types) and asthma can be cured, not just held at bay. This book shows the way. Dr. Pescatore is truly a healer."
–Roberta Flack, singer/songwriter

"I have seen firsthand how The Allergy and Asthma Cure has changed people’s lives for the better. I have started using his treatment protocols for my own patients with a remarkable success rate, and best of all with no side effects. Many of my patients are getting off their allergy and asthma medications completely. I strongly recommend this book to anyone with allergies or asthma."
–Dana G. Cohen, M.D., board-certified, Internal Medicine

"This book is for anyone willing to give up his or her life as an asthmatic. I had tried every drug and treatment available and the asthma only got worse. Under Dr. Pescatore’s care, I began to see results within six weeks. It’s been over two years now living without an attack. His approach has changed the way I live."
–Paul Goldman, patient

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New Generation Vaccines

New Generation Vaccines, Third Edition
by Myron M. Levine (Editor), James B. Kaper (Editor), Rino Rappuoli (Editor), Margaret A. Liu (Editor), Michael F. Good (Editor)

Product Details:
* Hardcover: 1120 pages
* Publisher: Informa Healthcare; 3 edition (January 28, 2004)
* Language: English
* ISBN-10: 0824740718

Book Description:
The past 10 years have seen an expanded scientific and commercial interest in the potential of new vaccines. Scientific advances have created new tools for developing vaccines for diseases for which no vaccines exist. The complete genomic sequence of a pathogen provides a catalogue of potential vaccine components. Improved techniques of protein purification and peptide synthesis facilitate the identification, isolation, and engineering of candidate vaccines. Novel adjuvants, formulations, and delivery systems to induce an optimal immune response have been developed. Recombinant-DNA techniques facilitate the construction of live vaccines, live vectors, or nucleic acid vaccines into which a gene coding for the vaccine antigen can be cloned. The vaccine market is also growing rapidly, and by the year 2000 it is estimated that it will reach a sales volume twice or even three times that of the early 1990s. Average annual growth rates of the vaccine business could, in the next few years, be above 10 percent, which will obviously stimulate research and development in academic institutions and commercial pharmaceutical companies.

Infections that are potentially preventable by vaccine remain major causes of morbidity and mortality worldwide. Infections caused 17 million deaths in 1996. Childhood immunizations prevent 3 million deaths every year, but an additional 8 million children could potentially be saved with new and improved vaccines. The spectrum of infectious diseases is expanding, and we have been challenged by many newly identified pathogens and syndromes. Also, the role of microbes as cofactors in chronic disease and disability emphasizes the importance of prevention. Good new vaccines would make a difference in all our lives.

The second edition of New Generation Vaccines introduces applications of molecular immunology and new ways of making vaccines (immunopotentiation, novel adjuvants, live and nonliving antigen delivery systems, and nucleic acid vaccines) in 20 chapters and describes new or improved vaccines in 40 chapters. It presents the various phases of vaccine development, ranging from the computer prediction of T-cell epitopes to the public health effect after implementation. Most of the chapters are balanced and up to date, but since there are 164 contributors, the presentation necessarily varies. The book covers both prevention and therapy as well as vaccines to prevent pregnancy or tumors. There are, however, surprising gaps -- e.g., vaccines against cytomegalovirus, measles, chlamydia, and group B streptococcal infections are not included.

The editors have looked for a compromise between detailed descriptions of individual vaccines and a general overview of the vaccine-development process. This has resulted in relatively short reviews on various topics. Although at first I liked the idea of having an introduction to economic analyses of vaccines or clinical evaluations of candidate vaccines, the chapters describing these seemed tangential to the main subject of the book and tended to be superficial. The same applies to the overviews of the vaccination programs and the commercial and regulatory aspects of vaccine production and distribution. Knowing the long and expensive developmental process of a new vaccine, I would have found interesting a description of the selection process of new candidates for development, including the political, commercial, and ethical implications. I realize, however, that 1215 pages are too few for both a thorough description of new vaccines and an introduction to other aspects of vaccine development. The publisher could expand these chapters and use them as a seed for another book: The Development and Evaluation of New Vaccines.

New Generation Vaccines is a valuable book for those who would like an overview of vaccines in the pipeline. Those who wish to learn about traditional vaccines and those who want detailed information about experiments with candidate vaccines need in most cases to look for other books and original articles. Vaccine researchers will find this book useful as an introduction to areas outside their own field. In general, it contains a lot of up-to-date information for those interested in future trends of infectious-disease prevention.

Progress in vaccinology is rapid. Therefore, future revised editions of this book will certainly be needed. If they are as readable and contain as much new information as the second edition, they will be most welcome. However, I hope that the weight of the book is kept within reasonable limits; future editions should not be expanded.

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The Pathogenic Enteric Protozoa: Giardia, Entamoeba, Cryptosporidium and Cyclospora

The Pathogenic Enteric Protozoa: Giardia, Entamoeba, Cryptosporidium and Cyclospora (World Class Parasites)
by Charles R. Sterling (Editor), Rodney D. Adam (Editor)

Product Details:
* Hardcover: 169 pages
* Publisher: Springer; 1 edition (March 31, 2004)
* Language: English
* ISBN-10: 1402077947

Book Description
The Pathogenic Enteric Protozoa: Giardia, Entamoeba, Cryptosporidium and Cyclospora compromise the health of millions of people, largely from developing nations. These protozoan parasitic agents contribute significantly to the staggering caseload of diarrheal disease morbidity encountered in developing world nations. Compounding the issue of their mere presence is the fact that standard ova and parasite exams frequently do not detect these infections. Detectable stages may be shed intermittently or require specialized staining procedures. Added to this is the often large number of asymptomatic carriers who serve as reservoirs for infecting others. These parasites are also not strangers to more developed nations, having responsibility for both small and large-scale disease outbreaks. In such settings they may be even more difficult to detect simply because they are frequently overlooked in the grand scheme of disease causing possibilities. They share common features: all are Protozoa, all possess trophic stages that inhabit the gastrointestinal tract, all have the ability to produce disease and in some instances death, and all produce environmentally stable cysts or oocysts, which ensure their transmissibility.

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