Hepatitis C Virus Disease: Immunobiology and Clinical Applications

Hepatitis C Virus Disease: Immunobiology and Clinical Applications
by Emilio Jirillo (Editor)

Product Details
Hardcover: 308 pages
Publisher: Springer; 1 edition (November 13, 2007)
Language: English
ISBN-10: 0387713751

Book Description
The Hepatitis C Virus is a major global health problem affecting more than 170 million people. HCV can eventually lead to cirrhosis, liver failure, and cancer in many instances. This volume will include comprehensive original papers that cover much of the past, current, and future literature that has appeared since the identification of the hepatitis C virus RNA genome. It will specifically deal with the effects of various types of interferons in basic research and clinical outcomes of HCV disease and its progression. The novelty of this publication will be that the immunobiology of HCV and the IFN-induced modification of the immune response will be emphasized more clearly then it has ever been in any other publication. It will be the immunobiology section that will help readers better understand the clinical efficacy of Interferon treatment. It will be a valuable volume for the student, researcher, or clinician interested in HCV transmission, molecular virology, immune response, cellular/molecular pathogenesis, and possibilities for developing effective new therapeutics and vaccines.

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Molecular Biology of Spirochete

Molecular Biology of Spirochetes (NATO Science Series: Life and Behavioural Sciences, Vol. 373)
by F. C. Cabello (Editor), D. Hulinska (Editor), H. P. Godfrey (Editor)

Product Details
Hardcover: 416 pages
Publisher: IOS Press; 1 edition (October 1, 2006)
Language: English
ISBN-10: 1586036653

Book Description
Diseases produced by spirochetes, including Lyme borreliosis, syphilis and leptospirosis, are on the rise worldwide, and because the biology of their causative organisms, their epidemiology, and clinical presentation display important variations in different geographical areas. For example B. burgdorferi sensu lato produces approximately 20,000 cases of Lyme borreliosis a year in the United States and 60,000 cases in Europe, but B. burgdorferi sensu stricto, B. afzelii and B. garinii are transmitted by different vectors and have different reservoirs and clinical presentations in these different geographic areas. Awareness and better understanding of these variations by researchers in the field is thus highly relevant to improvements in their prevention and treatment, and critical for improvement of human health. This volume focuses on a series of state-of-the-art presentations of the research taking place in the laboratories of the contributors. As such, it may be useful as an introduction to those individuals entering in the burgeoning field of spirochete research. This book could serve as a stimulus for researchers in the field to widen collaborations and exchanges between investigators in the different geographical areas where spirochetal diseases are common since these interactions can only be of benefit to the field.

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