Microbial Genomes (Infectious Disease)
by Claire M. Fraser (Editor), Timothy Read (Editor), Karen E. Nelson (Editor)

Product Details:
* Hardcover: 552 pages
* Publisher: Humana Press; 1 edition (April 9, 2004)
* Language: English
* ISBN-10: 1588291898

Book Description
This collection of diverse articles by the pioneers of modern genomics takes stock of the current state of the field and elucidates the contribution that sequencing genomes has made to our understanding of microbial metabolism and evolution. Through twenty-eight thought-provoking chapters, the authors describe some of the most common computational methods and their applications to studying pathogenic microorganisms, show how genomics can be used to reconstruct the history and dynamism of the microbial world, and discuss issues as diverse as reconstruction of metabolic pathways, cell cycle processes, microbial evolution, metagenomics, and vaccine development. Additional chapters deal with microarrays and expression analysis and the role of genomic in drug discovery.

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Interferon Methods and Protocols

Interferon Methods and Protocols (Methods in Molecular Medicine)
by Daniel J. J. Carr (Editor)

Product Details:
* Hardcover: 240 pages
* Publisher: Humana Press; 1 edition (June 1, 2005)
* Language: English
* ISBN-10: 1588294188

Book Description
A compendium of optimized methods to measure type I interferon efficacy as an antiproliferative or an antiviral agent. These cutting-edge techniques range from the simple to the highly complex and serve to illuminate the signaling cascades and the activation of enzymatic pathways prompted by interferon. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
State-of-the-art and highly practical, Interferon Methods and Protocols offers researchers powerful tools not only to ascertain the functions of IFN-stimulatory gene products, but also to identify additional molecular pathways that will clarify our understanding of the many biological events influenced by IFNs.

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