Dendritic Cells

Dendritic Cells (Handbook of Experimental Pharmacology) (Volume 188)
by Giovanna Lombardi (Editor), Yanira Riffo Vasquez (Editor)

Product Details
* Hardcover: 353 pages
* Publisher: Springer; 1 edition (December 16, 2008)
* Language: English
* ISBN-10: 3540710280

Book Description
This book provides in the first part an overview of dendritic cell (DC) biology and the role of DCs in some human diseases. The second part of the book illustrates some of the way that DCs can be manipulated for immunotherapy to either induce tolerance in autoimmunity and transplantation or enhance the immune responses such as in infection or cancer.

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TT Viruses: The Still Elusive Human Pathogens

TT Viruses: The Still Elusive Human Pathogens (Current Topics in Microbiology and Immunology)
by Ethel-Michele de Villiers (Editor), Harald zur Hausen (Editor)

Product Details
* Hardcover: 233 pages
* Publisher: Springer; 1 edition (December 16, 2008)
* Language: English
* ISBN-10: 3540709711

Book Description
Eleven years ago the circular DNA of a novel single-stranded virus has been cloned and partially characterized by Nishizawa and Okamoto and their colleagues. According to the initials of the patient from whom the isolate originated, the virus was named TT virus. This name has been subsequently changed by the International Committee on Taxonomy of Viruses (ICTV) into Torque teno virus, permitting the further use of the abbreviation TTV. Although initially suspected to play a role in non A –E hepatitis, subsequent studies failed to support this notion.
Within a remarkably short period of time it became clear that TT viruses are widely spread globally, infect a large proportion of all human populations studied thus far and represent an extremely heterogeneous group of viruses, now labelled as Anelloviruses. TT virus-like infections have also been noted in various animal species. The classification of this virus group turns out to be difficult, their DNA contains between 2200 and 3800 nucleotides, related so-called TT-mini-viruses and a substantial proportion of intragenomic recombinants further complicate attempts to combine these viruses into a unifying phylogenetic concept.

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