Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunology

Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunology (Current Topics in Microbiology and Immunology)
by Bruce Beutler

Product Details
* Hardcover: 14 pages
* Publisher: Springer; 1 edition (August 2008)
* Language: English
* ISBN-10: 3540752021

Book Description
This monograph deals with the impact of classical genetics in immunology, providing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who dont fully understand what the genetic approach is, and how it differs fundamentally from most of the methods available to natural scientists. They may hold the opinion that genetics has run its course since Mendel read his paper on peas in 1865. Why bother with classical genetics, they may ask. Wont all genes be knocked out soon anyway? Or they are intimidated by genetics, with its heavy reliance on model organisms that seem so alien. What has C. elegans to do with me? they may ask. It doesnt even have lymphocytes. They may be unaware that the mouse is fast becoming as tractable a model organism as the fly, and that humans may not be too far behind.

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Biotechnology of Extremophiles

Biotechnology of Extremophiles (Advances in Biochemical Engineering/Biotechnology)
by G. Antranikian (Editor)

Product Details
* Hardcover: 180 pages
* Publisher: Springer-Verlag Telos; 1 edition (August 1998)
* Language: English
* ISBN-10: 3540638172

Book Description
In this special issue review articles summarize the most outstanding features of microorganisms that can survive under extreme conditions. These microorganisms are adapted to living at 100° C in volcanic springs, at low temperatures in the cold polar seas, at high pressure in the deep sea, at very low and high pH values (pH 0-1 or pH 10-11), or at very high salt concentrations (35%). The latest findings on the molecular biology and the protein structure of these exotic organisms are presented. In addition, the potential applications of extremophiles are reviewed, including the production of enzymes, compatible solutes and the use of these extremophiles in the degradation of xenobiotics.

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