Human Herpesvirus-6, Volume 12, Second Edition: General Virology, Epidemiology and Clinical Pathology

Human Herpesvirus-6, Volume 12, Second Edition: General Virology, Epidemiology and Clinical Pathology (Perspectives in Medical Virology)
by Gerhard Krueger (Editor), D V Ablashi (Editor)

Product Details
* Hardcover: 392 pages
* Publisher: Elsevier Science; 2 edition (September 14, 2006)
* Language: English
* ISBN-10: 0444520635

Book Description
The present book presents a comprehensive review of Human Herpesvirus-6 (HHV-6) infects up to 90% of the worlds population and can cause potentially life-threatening diseases. Clinicians typically do not search for HHV-6, and if they do, they will find only few laboratories providing the necessary diagnostic tests that can differentiate between active and latent infection. Adding to this problem is that scientists still disagree about whether serological or molecular assays will be the best diagnostic test, yet there is no disagreement about the inadequacy of many of the currently existing assays. Consequently, our knowledge of etiology and pathogenesis of HHV-6 associated diseases can only come from the combined efforts of clinicians, virologists, molecular biologists and pathologists. It is the prime task of this book to summarize the status quo of HHV-6 research and to further stimulate such a collaboration. It will be a valuable reference for both clinical and basic scientists including epidemiologists, virologists, practicing clinicians and infectiologists, pathologists and essentially all scientists entering the field of herpes virus research.

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Genetics of Bacterial Polysaccharides

Genetics of Bacterial Polysaccharides
by Joanna B. Goldberg (Editor)

Product Details
* Hardcover: 256 pages
* Publisher: CRC; 1 edition (April 30, 1999)
* Language: English
* ISBN-10: 0849300215

Book Description:
Bacterial surface or secreted polysaccharides are molecules that can function as barriers to protect bacterial cells against environmental stresses, as well as act as adhesins or recognition molecules. In some cases, these molecules are immunodominant antigens eliciting a vigorous immune response, while in other cases the expression of polysaccharides camouflages the bacteria from the immune system. Until recently, most studies on the enzymatic steps and regulation of these molecules were performed on the enteric gram negative bacteria Escherichia coli and Salmonella typhimurium. With the advent of modern bacterial genetics, techniques such as construction and characterization of polysaccharide mutants, cloning of genes and complementation of these mutations, and expression of polysaccharides in heterologous bacterial hosts has prompted investigations into the roles and functions of these molecules for many different bacteria. Here, we present the genetic analysis of polysaccharides from a number of bacteria pathogenic to humans and one symbiotic with plants in hopes that similarities in the experimental approaches as well as finding s from such investigations may lead to a general understanding of polysaccharide synthesis and regulation in various bacteria.

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