Nature Reviews Immunology - Jan 2008

Nature Reviews Immunology Jan 2008

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New Vaccine Development: Establishing Priorities: Volume II, Diseases of Importance in Developing Countries

New Vaccine Development: Establishing Priorities: Volume II, Diseases of Importance in Developing Countries
by Division of Health Promotion and Disease Prevention (Author), Division of International Health (Author)

Product Details
Paperback: 432 pages
Publisher: National Academies Press (January 1, 1986)
Language: English
ISBN-10: 0309036798

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Agrobacterium

Agrobacterium
by Tzvi Tzfira (Editor), Vitaly Citovsky (Editor)

Product Details
Hardcover: 504 pages
Publisher: Springer; 1 edition (January 25, 2008)
Language: English
ISBN-10: 0387722890

Book Description
Agrobacterium is a plant pathogen which causes the "crown-gall" disease, a neoplastic growth that results from the transfer of a well-defined DNA segment ("transferred DNA", or "T-DNA") from the bacterial Ti (tumor-inducing) plasmid to the host cell, its integration into the host genome, and the expression of oncogenes contained on the T-DNA. The molecular machinery, needed for T-DNA generation and transport into the host cell and encoded by a series of chromosomal (chv) and Ti-plasmid virulence (vir) genes, has been the subject of numerous studies over the past several decades. Today, Agrobacterium is the tool of choice for plant genetic engineering with an ever expanding host range that includes many commercially important crops, flowers, and tree species. Furthermore, its recent application for the genetic transformation of non-plant species, from yeast to cultivated mushrooms and even to human cells, promises this bacterium a unique place in the future of biotechnological applications

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Rheumatic Diseases: Immunological Mechanisms and Prospects for New Therapies

Rheumatic Diseases: Immunological Mechanisms and Prospects for New Therapies
by J. S. H. Gaston (Editor)

Product Details
Hardcover: 288 pages
Publisher: Cambridge University Press; 1 edition (August 15, 1999)
Language: English
ISBN-10: 0521593271

Book Description
This authoritative volume provides a wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases. Advances in our understanding of the immunopathology of diseases such as rheumatoid arthritis, ankylosing spondylitis and SLE, are paving the way for the development of effective and rational new therapies. This exciting prospect is an important influence for ground-breaking research into these diseases and the investigation of new therapeutic options. As the first book to focus exclusively on this burgeoning area of clinical research, this is an invaluable and current resource for all rheumatologists, clinical immunologists, and those seeking to develop effective new therapies to combat rheumatic diseases.

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