Techniques for Immune Function Analysis

Techniques for Immune Function Analysis - Application Handbook (1st Edition)

The study of the immune system attracts large numbers of researchers from
diverse scientific disciplines because of its central importance in providing
immunological host defense and its intercommunication with other systems that
maintain bodily homeostasis. The immune system is often studied in its intact
form but it can also be readily disassembled into its cellular and molecular
components (eg, lymphoid cell populations and effector molecules), recombined
and modified in various ways, and analyzed in an in vitro or an in vivo setting.
Due to the creative development and application of a wide variety of
experimental protocols, often using new technological platforms and reagents,
vast amounts of new information concerning immune function become available
on a daily basis. Researchers busily scrutinize this information hoping to better
define and understand the networks of cellular and molecular mechanisms that
underlie immunity and inflammation in health and disease.

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E. coli in Motion

E. coli in Motion (Biological and Medical Physics, Biomedical Engineering)
by Howard C. Berg (Author)

Product details:
* Hardcover: 145 pages
* Publisher: Springer-Verlag New York Inc. (Oct 2003)
* Language English
* ISBN-10: 0387008888
* ISBN-13: 978-0387008882

Book Description:
The bacterium Escherichia coli – E. coli for short – has long been the organism of choice for unraveling biochemical pathways, deciphering the genetic code, learning how DNA is replicated and read, and even for manufacturing proteins of commercial interest. For some thirty years, it also has been a model for studying the molecular biology of behavior. E. coli swims in a purposeful manner, propelled by long thin helical filaments, each driven at its base by a reversible rotary engine. As a microscopic organism immersed in an aqueous environment, it has mastered physical constraints utterly different from any that we know, devising sensors, comparators, and motors on the nanometer scale.

This cross-disciplinary monograph describes these feats in a manner accessible to scientists, engineers, and others not trained in microbiology who would like to learn more about living machines. It treats the history of the subject, the physiology, physics, biochemistry and genetics, largely from first principles. It is all about a small but remarkably sophisticated friend who lives in your gut.

Topics discussed include:
How does E. coli move about?
How do cells decide whether life is getting better or worse?
What is the machinery that makes this behavior possible?
How is the construction of this machinery programmed?
How does this machinery work?
What remains to be discovered?

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