Structural Biology of the Complement System

Structural Biology of the Complement System
by Dimitrios Morikis (Editor), John D. Lambris (Editor)

Product Details:
* Hardcover: 370 pages
* Publisher: CRC; Har/Cdr edition (March 29, 2005)
* Language: English
* ISBN-10: 0824725409

Book Description:
The only in-depth guide on the subject, this is the first resource to present the structural biology of the complement system in connection to immunology and drug development. Integrating the latest breakthroughs in structural biology and immunology, this book includes detailed discussions of the structure-function relationships among complement system components, regulators, receptors, and selected proteins and inhibitor. It also provides an introduction to the structural bioinformatics classification of complement proteins. The book comes with a CD containing color figures, a molecular structure visualization program, and files with three-dimensional coordinates of the structures.

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Cancer and Autoimmunity

Cancer and Autoimmunity (Autoanitbody Library)
by Y. Shoenfeld (Editor), M.E. Gershwin (Editor)

Product Details:
* Hardcover: 468 pages
* Publisher: Elsevier Science; 1st edition (March 1, 2000)
* Language: English
* ISBN-10: 0444503315

Book Description
Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike.
The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer in vivo, possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival.
This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art.
This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology.

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Methods in Cellular Immunology

Methods in Cellular Immunology, Second Edition
by Rafael Fernandez-Botran (Author), Vaclav Vetvicka (Author)

Product Details:
* Spiral-bound: 272 pages
* Publisher: CRC; 2 edition (June 26, 2001)
* Language: English
* ISBN-10: 0849309220

Book Description
This text is a step-by-step guide to commonly used procedures in cellular immunology. It addresses both human and murine models, in addition to such topics as PCR and APOPTOSIS. The work includes extensive references that allow the reader to compare original techniques. It also lists manufacturers of all chemicals and materials used in the procedures.

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