Atomic Force Microscopy: Biomedical Methods and Applications

Atomic Force Microscopy: Biomedical Methods and Applications (Methods in Molecular Biology)
by Pier Carlo Braga (Editor), Davide Ricci (Editor)

Product Details:
* Hardcover: 408 pages
* Publisher: Humana Press; 1 edition (October 2, 2003)
* Language: English
* ISBN-10: 1588290948

Book Description
Highly experienced physicians and biologists clearly explain the basic technical knowledge needed to use AFM and demonstrate its multifarious uses in biomedicine and the life sciences. The applications range widely from morphostructural analyses of cellular structures, to the investigation of subcellular structures, to functional investigations, and reveal a powerful new way of looking at biological samples. The methods clearly demonstrate the advantages of AFM over traditional life science microscopy, among them simultaneous very high magnification and resolution, minimal tissue and cell preparation, and the ability to obtain different views of the sample from a single data collection.

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Confocal Microscopy Methods and Protocols

Confocal Microscopy Methods and Protocols (Methods in Molecular Biology)
by Stephen W. Paddock (Editor)

Product Details:
* Paperback: 446 pages
* Publisher: Humana Press; 1 edition (January 15, 1999)
* Language: English
* ISBN-10: 0896035263


Book Description
Stephen Paddock and a highly skilled panel of experts lead the researcher using confocal techniques from the bench top, through the imaging process, to the journal page. They concisely describe all the key stages of confocal imaging-from tissue sampling methods, through the staining process, to the manipulation, presentation, and publication of the realized image. Written in a user-friendly, nontechnical style, the methods specifically cover most of the commonly used model organisms: worms, sea urchins, flies, plants, yeast, frogs, and zebrafish. The powerful hands-on methods collected here will help even the novice to produce first-class cover-quality confocal images.

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Nonviral Vectors for Gene Therapy

Nonviral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
by Mark A. Findeis (Editor)

Product Details:
* Hardcover: 416 pages
* Publisher: Humana Press; 1 edition (August 9, 2001)
* Language: English
* ISBN-10: 0896037126

Book Description
Mark A. Findeis and a panel of active researchers present their best methods not only for preparing, handling, and characterizing gene delivery agents, but also for gene delivery. To help those preparing and characterizing gene transfer agents, the contributors examine a broad range of compounds that bind with DNA to form the compact condensed phases that facilitate cellular delivery-among them peptide conjugates, synthetic polymers, and lipids. They also outline specific approaches to gene transfer in vivo, including direct delivery by intratumoral injection and indirect delivery by cell-specific targeting of DNA complexes, and discuss in detail many spectroscopic techniques for characterizing nonviral gene delivery agents.

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