Aging, Immunity, and Infection

Aging, Immunity, and Infection (Infectious Disease)
by Joseph F. Albright (Author), Julia W. Albright (Author)

Product Details:
* Hardcover: 256 pages
* Publisher: Humana Press; 1 edition (January 15, 2003)
* Language: English
* ISBN-10: 0896036448

Book Description
Two prominent immunogerontologists review the major features and functions of the immune system that are most likely, or known, to be significantly altered by aging, and offer insightful analyses of the consequences for those aging subjects who must cope with infection. Topics of special interest include the demographics and theories of immunosenescence, the gradual breakdown of resistance to infection in the aged, and the effects of aging on selected mechanisms of both innate and adaptive immunity to infections. The Albrights also explain how advances may be made in understanding the basic biology, the newer methods of treatment and prevention, and the evaluation of such provocative ideas as lifespan extension and nutritional intervention to delay immunosenescence.

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Clinical Applications of PCR

Clinical Applications of PCR (Methods in Molecular Biology)
by Y.M. Dennis Lo (Author), W.K. Chiu Rossa (Author), Allen Chan (Author)

Product details:
* Hardcover: 216 pages
* Publisher: Humana Press Inc.,U.S.; 2Rev Ed edition (Mar 2006)
* Language English
* ISBN-10: 1588293483

Book Description
In this updated second edition, leading researchers apply molecular diagnostics to the many recent advances that have occurred in polymerase chain reaction(PCR)-based technologies. Highlights include real-time PCR, which allows the technique to be performed in a quantitative manner with improved sensitivity, robustness, and resilience to carry over contamination, mass spectrometric analysis of nucleic acids, and circulating cell-free nucleic acids in plasma. The authors apply these innovations to a broad spectrum of applications, including gene expression, methylation, trace molecule, gene dosage, and single cell analysis.

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