Brain Tumor Immunotherapy

Brain Tumor Immunotherapy
by Linda M. Liau (Editor), Donald P. Becker (Editor), Timothy F. Cloughesy (Editor), Darell D. Bigner (Editor)

Product Details:
* Hardcover: 373 pages
* Publisher: Humana Press; 1st edition (January 15, 2001)
* Language: English
* ISBN-10: 0896036383


Book Description
An authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying brain tumor immunotherapy. Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.

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Cytokine Inhibitors

Cytokine Inhibitors
by Gennaro Ciliberto (Editor)

Product Details:
* Hardcover: 372 pages
* Publisher: CRC; 1st edition (January 15, 2001)
* Language: English
* ISBN-10: 0824704347

Book Description:
Compiling an up-to-date and detailed survey of the role cytokines play in cell-to-cell communication, development, and differentiation, this comprehensive reference highlights the medical advantages of cytokine inhibition and pursues novel methods of discovery for more potent and specific blocking agents. Investigates the pathogenic role of cytokines and the potential of cytokine inhibitors as anti-inflammatory, anticancer, antiviral agents! Written by 25 recognized experts revealing recent breakthroughs in research, Cytokine Inhibitors · illustrates cases of naturally produced or in vitro engineered polypeptide cytokine blocking agents · describes all possible approaches to cytokine inhibitors, including monoclonal antibodies, soluble receptors, engineered mutant cytokines, and small-molecular-weight receptor antagonists and signaling inhibitors · clearly explains the homeostatic function of cytokine inhibition and verifies therapeutic approaches effecting natural responses in organisms · discusses the results of clinical trials and therapeutic applications of first-generation recombinant receptor antagonists, such as the potential of tumor necrosis factor antagonists as prominent tools in the therapy of chronic inflammatory conditions · concentrates on the clinical development of second-generation small-molecular-weight, orally bioavailable cytokine inhibitors · reviews the improved understanding of intracellular signaling pathways, the structural determinants responsible for cytokine-receptor interaction · lists the three-dimensional structure, relevant receptors, and intracellular tyrosine kinases of cytokines · and much more! Containing over 1400 references as well as tables and drawings, Cytokine Inhibitors serves as an exemplary reference for basic and clinical immunologists; allergists; biochemists; pathologists, hematologists; experimental, cell, and molecular biologists; rheumatologists; infectious disease specialists; medicinal chemists; and medical school and upper-level undergraduate and graduate students in these disciplines.

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