Transplantation Immunology: Methods and Protocols

Transplantation Immunology: Methods and Protocols (Methods in Molecular Biology)
by Philip Hornick (Editor)

Product Details:
* Hardcover: 440 pages
* Publisher: Humana Press; 1 edition (March 1, 2006)
* Language: English
* ISBN-10: 1588295443

Book Description
Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.

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Integrins

Integrins, Volume 426 (Methods in Enzymology)
by David A. Cheresh (Editor)

Product Details:
* Hardcover: 500 pages
* Publisher: Academic Press (August 27, 2007)
* Language: English
* ISBN-10: 0123739241

Book Description
An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. It plays a role in the attachment of a cell to the extracellular matrix (ECM) and to other cells, and in signal transduction from the ECM to the cell. There are many types of integrin, and many cells have multiple types on their surface. Integrins are of vital importance to all metazoans, from humans to sponges. This volume in Methods in Enzymology presents methods for studying integrins.

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