Mobile Genetic Elements

Mobile Genetic Elements: Protocols and Genomic Applications (Methods in Molecular Biology)
by Wolfgang J. Miller (Editor), Pierre Capy (Editor)

Product Details
* Hardcover: 300 pages
* Publisher: Humana Press (April 2004)
* Language: English
* ISBN-10: 1588290077
* ISBN-13: 978-1588290076

Book Description:
Transposable elements (TEs), DNA sequences that can move from one chromosome location to another, are found in all living organisms. Here experts take you step-by-step through their most successful transposon-based protocols and strategies for studying genome structure, function and evolution. Such TE-derived techniques have been used for a variety of purposes, ranging from mutagenesis, gene slicing, transgenesis, and polymorphic marker systems. These readily-reproducible techniques cover a broad range, including mutagenesis, transgenesis, gene slicing, and molecular systematics. In particular, there are a series of DNA hybridisation methods for analysing the distribution and dynamics of mobile DNA at the host’s genomic level, techniques for studying LTR retrotransposons in heterologous host systems and mutagenesis protocols for investigating gene functions in a broad range of organisms.

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Principles and Practice of Clinical Bacteriology

Principles and Practice of Clinical Bacteriology
by Stephen H. Gillespie and Peter Hawkey

Product Details
* Hardcover: 620 pages
* Publisher: John Wiley & Sons; 2 edition (March 10, 2006)
* Language: English
* ISBN-10: 0470849762
* ISBN-13: 978-0470849767

Book Description:
Since the first edition of Principles and Practice of Clinical Bacteriology in 1997, there has been a revolution in the discipline of microbiology. The availability of whole genome sequences has transformed our understanding of bacterial genetics, while new technologies such as proteomics and transcriptomics have greatly enhanced our insight into pathogenicity.

The application of computers to this stream of knowledge has enabled microbiologists to see pathogens in a new way and develop new theories explaining the pathogenesis of infection and to identify new targets for anti-microbial chemotherapy.

In this new, Second Edition, internationally recognised editors and contributors comprehensively describe the various aspects of clinical bacteriology.

Each chapter has been updated to include the most recent information and expanded to include more thorough treatment of the relevant drugs, molecular diagnosis and infection control.

Table of Contents:
List of Contributors.

Preface.

SECTION ONE: GRAM-POSITIVE COCCI.

1 Beta-Haemolytic Streptococci (Androulla Efstratiou, Shiranee Sriskandan, Theresa Lamagni and Adrian Whatmore).
2 Oral and Other Non-Beta-Haemolytic Streptococci (Roderick McNab and Theresa Lamagni).
3 Streptococcus pneumoniae (Indran Balakrishnan).
4 Enterococcus spp. (Esteban C. Nannini and Barbara E. Murray).
5 Staphylococcus aureus (Sharon Peacock).
6 Coagulase-Negative Staphylococci (Roger G. Finch).

SECTION TWO: GRAM-POSITIVE BACILLI.

7 Corynebacterium spp. (Aruni De Zoysa and Androulla Efstratiou).
8 Listeria and Erysipelothrix spp. (Kevin G. Kerr).
9 Bacillus spp. and Related Genera (Niall A. Logan and Marina Rodríguez-Díaz).
10 Mycobacterium tuberculosis (Stephen H. Gillespie).
11 Non-Tuberculosis Mycobacteria (Stephen H. Gillespie).
12 Aerobic Actinomycetes (Stephen H. Gillespie).

SECTION THREE: GRAM-NEGATIVE ORGANISMS.

13 Moraxella catarrhalis and Kingella kingae (Alex van Belkum and Cees M. Verduin).
14 Neisseria meningitidis (Dlawer A. A. Ala’Aldeen and David P. J. Turner).
15 Neisseria gonorrhoeae (Catherine A. Ison).
16 Acinetobacter spp. (Peter Hawkey and Eugenie Bergogne-Berezin).
17 Haemophilus spp. (Derrick W. Crook and Derek W. Hood).
18 Bordetella spp. (Qiushui He, Jussi Mertsola and Matti K. Viljanen).
19 Brucella spp. (Edward J. Young).
20 Actinobacillus actinomycetemcomitans (Brian Henderson and Derren Ready).
21 Francisella tularensis (Petra C. F. Oyston).
22 Rickettsia spp. (James G. Olson, Franca R. Jones and Patrick J. Blair).
23 Bartonella spp. (J. M. Rolain and D. Raoult).
24 Mycoplasma spp. (Christiane Bébéar, Sabine Pereyre and Cécile M. Bébéar).
25 Chlamydia spp. and Related Organisms (S. J. Furrows and G. L. Ridgway).
26 Tropheryma whipplei (F. Fenollar and D. Raoult).
27 Identification of Enterobacteriaceae (Peter M. Hawkey).
28 Escherichia coli and Shigella spp. (Christopher L. Baylis, Charles W. Penn, Nathan M. Thielman, Richard L. Guerrant, Claire Jenkins and Stephen H. Gillespie).
29 Salmonella spp. (Claire Jenkins and Stephen H. Gillespie).
30 Klebsiella, Citrobacter, Enterobacter and Serratia spp. (C. Anthony Hart).
31 Donovanosis and Klebsiella spp. (John Richens).
32 Proteus, Providencia and Morganella spp. (Peter M. Hawkey).
33 Yersinia spp. (M. B. Prentice).
34 Vibrio spp. (Tom Cheasty).
35 Aeromonas and Plesiomonas spp. (Alpana Bose).
36 Pseudomonas and Burkholderia spp. (Tyrone L. Pitt and Andrew J. H. Simpson).
37 Legionella spp. (T. G. Harrison).
38 Coxiella burnetii (James G. Olson, Franca R. Jones and Patrick J. Blair).

SECTION FOUR: SPIRAL BACTERIA.

39 Leptospira spp. (P. N. Levett).
40 Helicobacter spp. and Related Organisms (Peter J. Jenks).
41 Campylobacter and Arcobacter spp. (Diane E. Taylor and Monika Keelan).
42 Treponemes (Andrew J. L. Turner).
43 Borrelia spp. (Sudha Pabbatireddy and Benjamin J. Luft).

SECTION FIVE: OBLIGATE ANAEROBIC BACTERIA.

44 Anaerobic Cocci (D. A. Murdoch).
45 Non-Sporing Gram-Negative Anaerobes (Sheila Patrick and Brian I. Duerden).
46 Clostridium difficile (Mark H. Wilcox).
47 Other Clostridium spp. (Ian R. Poxton).
48 Anaerobic Actinomycetes and Related Organisms (Val Hall).

Index.

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Fundamental Immunology (Paul)

Fundamental Immunology
Author(s): William E. Paul, MD

Product Details:
Edition:5th ed.
Year:2003
ISBN-10:0781714125
ISBN-13:9780781714129
Pages:1616
Illustrations:501

Book Info:
Fundamental Immunology provides an encyclopedic overview of the rapidly expanding field of immunology, with bioscience information critical to understanding how the immune system functions. Its insightful discussions describe the role the immune system plays in the prevention and pathogenesis of disease, making it a truly vital resource for the comprehensive study of this field.

The text lays the foundation for the study of immunology and discusses the structure and function of the molecular components of immunity. Major sections provide pertinent information on system- and organ-specific autoimmunity; transplantation and tumor immunology; viruses, bacteria, and parasites; primary immunodeficiency diseases and the immunopathogenesis of HIV infection; and vaccines.

Table of Contents

1. Introduction
1. The Immune System: An Introduction
2. History of Immunology

2. Immunoglobulins and B Lymphocytes
3. Immunoglobulins: Structure and Function
4. Antigen-Antibody Interactions and Monoclonal Antibodies
5. Immunoglobulins: Molecular Genetics
6. B-Lymphocyte Development and Biology
7. B-Cell Signaling Mechanisms and Activation

3. T Cells and NK Cells
8. T-Cell Antigen Receptors
9. T-Cell Developmental Biology
10. Peripheral T-Lymphocyte Responses and Function
11. T-Lymphocyte Activation
12. Natural Killer Cells
13. Accessory Molecules and Co-Stimulation

4. Organization and Evolution of the Immune System
14. Lymphoid Tissues and Organs
15. Dendritic Cells
16. Macrophages and the Immune Response
17. Innate Immune System
18. Evolution of the Immune System

5. Antigen Processing and Presentation
19. The Major Histocompatibility Complex and Its Encoded Proteins
20. The Biochemistry and Cell Biology of Antigen Processing

6. Regulation of the Immune Response
21. Immunogenicity and Antigen Structure
22. Fc Receptors
23. Type I Cytokines and Interferons and Their Receptors
24. The Tumor Necrosis Factor Superfamily and its Receptors
25. Interleukin-1 Family of Ligands and Receptors
26. Chemokines
27. Programmed Cell Death
28. Immunologic Memory
29. Immunological Tolerance
30. Regulatory/Suppressor T Cells
31. The Mucosal Immune System
32. Neural Immune Interactions in Health and Disease
33. Immunology of Aging

7. Effector Mechanisms of Immunity
34. Complement
35. Phagocytosis
36. Cytotoxic T Lymphocytes
37. Inflammation

8. Immunity to Infectious Agents
38. The Immune Response to Parasites
39. Viral Immunology
40. Immunity to Intracellular Bacteria
41. Immunity to Extracellular Bacteria
42. Immunology of HIV Infection
43. Vaccines

9. Immunologic Mechanisms in Disease
44. Systemic Autoimmunity
45. Organ-Specific Autoimmunity
46. Immunological Mechanisms of Allergic Disorders
47. Transplantation Immunology
48. Tumor Immunology
49. Primary Immunodeficiency Diseases
50. Immunotherapy

Subject Index

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Bacteria And Other Micro Organisms

Bacteria And Other Micro Organisms

Book Properties:
ISBN: 9057680246
Title: Bacteria And Other Micro Organisms
Publisher: Pepin Press
Publication Date: 2004-12-31
Number Of Pages: 128

Book Info:
This book contains stunning images for use as a graphic resource, or inspiration. All the illustrations are stored in high-resolution format on the enclosed free CD-ROM and are ready to use for professional quality printed media and web page design. The pictures can also be used to produce postcards, or to decorate your letters, flyers, etc. They can be imported directly from the CD into most design, image- manipulation, illustration, word-processing and e-mail programs; no installation is
required. For most applications, single images can be used free of charge. Please consult the introduction to this book, or visit our website for conditions.

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Anaphylaxis

Anaphylaxis (Novartis Foundation Symposia)

Product Details:»Book Publisher: John Wiley & Sons (12 March, 2004)
»ISBN: 0470861142
»Book author: Novartis Foundation

Book Description:
Anaphylaxis is an immediate-type allergic reaction involving the whole organism. It is the most life-threatening allergic condition. Although there are few exact epidemiological data regarding prevalence, estimates regarding insect sting anaphylaxis range from 1-3 0n the general population, but much higher values have been reported by some authors for food and drug-induced anaphylaxis. Anaphylaxis is the main acute killer of allergic individuals.
Although anaphylaxis was discovered at the beginning of the 20th century, there are still many unresolved issues. These include non-IgE-mediated anaphylactoid reactions, non-immunologically mediated anaphylactoid (pseudo-allergic) reactions, pathophysiological events at the microcirculatory level, appropriate therapy for the acute reaction, strategies for prevention, public education about the problem and new approaches to prevention and therapy at the IgE level. All these subjects are discussed in this book.
Since anaphylaxis occurs acutely and is unforeseen, it is very difficult to organize controlled studies regarding therapy and prevention. The spectrum of symptomatology covers many clinical areas (skin, respiratory, cardiovascular and gastrointestinal system), therefore inter-disciplinary approaches are necessary for progress in the field. There is widespread uncertainty among physicians about therapy, especially concerning self-administered treatment.
In this important book, an multidisciplinary group of experts explore the pathophysiology of different types of anaphylactic and anaphylactoid reactions. Evidence is presented on the epidemiology of these conditions while problems relating to diagnosis, therapy and prevention are examined in detail. This thorough and up-to-date coverage of the subject will be of great interest to all clinical immunologists, researchers and physicians who deal with this life-threatening condition.

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