Fundamental Immunology (Paul)

Fundamental Immunology
Author(s): William E. Paul, MD

Product Details:
Edition:5th ed.
Year:2003
ISBN-10:0781714125
ISBN-13:9780781714129
Pages:1616
Illustrations:501

Book Info:
Fundamental Immunology provides an encyclopedic overview of the rapidly expanding field of immunology, with bioscience information critical to understanding how the immune system functions. Its insightful discussions describe the role the immune system plays in the prevention and pathogenesis of disease, making it a truly vital resource for the comprehensive study of this field.

The text lays the foundation for the study of immunology and discusses the structure and function of the molecular components of immunity. Major sections provide pertinent information on system- and organ-specific autoimmunity; transplantation and tumor immunology; viruses, bacteria, and parasites; primary immunodeficiency diseases and the immunopathogenesis of HIV infection; and vaccines.

Table of Contents

1. Introduction
1. The Immune System: An Introduction
2. History of Immunology

2. Immunoglobulins and B Lymphocytes
3. Immunoglobulins: Structure and Function
4. Antigen-Antibody Interactions and Monoclonal Antibodies
5. Immunoglobulins: Molecular Genetics
6. B-Lymphocyte Development and Biology
7. B-Cell Signaling Mechanisms and Activation

3. T Cells and NK Cells
8. T-Cell Antigen Receptors
9. T-Cell Developmental Biology
10. Peripheral T-Lymphocyte Responses and Function
11. T-Lymphocyte Activation
12. Natural Killer Cells
13. Accessory Molecules and Co-Stimulation

4. Organization and Evolution of the Immune System
14. Lymphoid Tissues and Organs
15. Dendritic Cells
16. Macrophages and the Immune Response
17. Innate Immune System
18. Evolution of the Immune System

5. Antigen Processing and Presentation
19. The Major Histocompatibility Complex and Its Encoded Proteins
20. The Biochemistry and Cell Biology of Antigen Processing

6. Regulation of the Immune Response
21. Immunogenicity and Antigen Structure
22. Fc Receptors
23. Type I Cytokines and Interferons and Their Receptors
24. The Tumor Necrosis Factor Superfamily and its Receptors
25. Interleukin-1 Family of Ligands and Receptors
26. Chemokines
27. Programmed Cell Death
28. Immunologic Memory
29. Immunological Tolerance
30. Regulatory/Suppressor T Cells
31. The Mucosal Immune System
32. Neural Immune Interactions in Health and Disease
33. Immunology of Aging

7. Effector Mechanisms of Immunity
34. Complement
35. Phagocytosis
36. Cytotoxic T Lymphocytes
37. Inflammation

8. Immunity to Infectious Agents
38. The Immune Response to Parasites
39. Viral Immunology
40. Immunity to Intracellular Bacteria
41. Immunity to Extracellular Bacteria
42. Immunology of HIV Infection
43. Vaccines

9. Immunologic Mechanisms in Disease
44. Systemic Autoimmunity
45. Organ-Specific Autoimmunity
46. Immunological Mechanisms of Allergic Disorders
47. Transplantation Immunology
48. Tumor Immunology
49. Primary Immunodeficiency Diseases
50. Immunotherapy

Subject Index

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