New Antibiotic Targets

New Antibiotic Targets (Methods in Molecular Medicine)
By W. Scott Champney

Product Details
* Hardcover: 296 pages
* Publisher: Humana Press; 1 edition (January 15, 2008)
* Language: English
* ISBN-10: 1588299155

Book Description
A crisis is developing in the treatment of infectious diseases, with microorganisms frequently showing resistance to currently prescribed antibiotics. Fewer and fewer antimicrobial agents are now available to treat these infections. In New Antibiotic Targets, W. Scott Champney examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. By testing new antimicrobial agents and modified existing drugs, the most vulnerable cell processes, such as cell wall and membrane synthesis, DNA replication, RNA transcription and protein synthesis, can be better exploited. This in-depth volume, however, delves even deeper by identifying additional novel cellular targets for these new therapies.
New Antibiotic Targets provides laboratory investigators with the vital tools they need to test the antimicrobial potential of products and to curb the rise of so many infectious diseases.

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Handbook of Human Immunology

Handbook of Human Immunology, Second Edition
by Maurice R.G. O'Gorman (Editor), Albert D. Donnenberg (Editor)

Product Details
* Hardcover: 640 pages
* Publisher: CRC; 2 edition (February 15, 2008)
* Language: English
* ISBN-10: 0849319846

Book Description
Since the publication of the first edition of the Handbook of Human Immunology in 1997, major scientific achievements have elucidated our understanding of the complexities of the human immune system. This second edition compiles the major breakthroughs of the past decade including dramatic increases in the number of recognized clusters of differentiation on the surface of leukocytes and associated cells, establishment of an entire new chemokine and chemokine receptor nomenclature system, and discovery of more than 30 lymphokines. The text emphasizes clinically relevant immunological parameters, and clarifies the basic principles underlying immune system assays, as well as applications and interpretations of immune tests.

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