Current Topics in Innate Immunity

Current Topics in Innate Immunity (Advances in Experimental Medicine and Biology)
by John D., Ed. Lambris (Author)

Product Details:
* Hardcover: 438 pages
* Publisher: Springer; 1 edition (August 22, 2007)
* Language: English
* ISBN-10: 038771765X

Book Description
Innate Immunity has long been regarded as the non-specific arm of immune response, acting immediately and in a generic way, to defend the host from infections. In the post genomic era, our knowledge of the innate immune system is enriched by findings on the specificity of innate immune reactions as well as to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or inflammation. Several studies indicate that molecules involved in innate immunity exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system.
The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led scientists to revisit established biological systems from a global and integrative perspective. Innate Immunity research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory circuits. In this respect, scientists from around the world convened at the 4th International Conference on Innate Immunity (June 4 - 9, 2006), in Corfu, Greece to discuss recent advances in this fast evolving field.
This volume represents a collection of topics on natural killer cells, mast cells, phagocytes, toll like receptors, complement, host defense in plants and invertebrates, evasion strategies of microorganisms, pathophysiology, protein structures, design of therapeutics, and experimental approaches discussed during the conference.

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Cryopreservation and Freeze-Drying Protocols

Cryopreservation and Freeze-Drying Protocols (Methods in Molecular Biology)
by John G. Day (Editor), Glyn N. Stacey (Editor)

Product Details:
* Hardcover: 348 pages
* Publisher: Humana Press; 2nd ed. edition (June 5, 2007)
* Language: English
* ISBN-10: 1588293777

Book Description
Cryopreservation and Freeze-Drying Protocols: Second Edition is a compilation of robust, reproducible techniques for the conservation of a wide range of biological materials. This widely expanded second edition includes novel approaches and protocols for biological materials that were not preservable when the first edition was published in 1995.
This volume begins with a discussion of long term ex situ conservation of biological resources, the role of biological resource centers, and fundamental principles of freeze-drying and cryopreservation. Each chapter focuses on the preservation of specific biological materials, including proteins, mircroorganisms, cell lines, and multicellular structures. Detailed descriptions of materials required and stepwise protocols are presented for each preservation method, along with explanatory notes that highlight key technical issues. The troubleshooting and background notes provided for each protocol enhance this practical and reliable resource for the conservation and sustainable use of biological resources.

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Halophilic Microorganisms and their Environments

Halophilic Microorganisms and their Environments (Cellular Origin, Life in Extreme Habitats and Astrobiology)
by A. Oren (Author)

Product Details:
* Hardcover: 600 pages
* Publisher: Springer; 1 edition (August 31, 2002)
* Language: English
* ISBN-10: 1402008295

Book Description
The halophilic microorganisms form a highly diverse group of organisms. They present the biochemist/physiologist with interesting questions on the strategies used to cope with high osmotic pressures exerted by hypersaline brines. They often have a strong impact on the ecosystems in which they thrive. The first section of the book presents in-depth discussions of the taxonomy, cellular properties, metabolic diversity, pigments, ion metabolism and organic osmotic solutes, properties of halophilic proteins, genetics, and biotechnological uses of halophilic microorganisms. The second section describes the occurrence and functioning of these organisms in the Great Salt Lake, the Dead Sea, solar saltern ponds, alkaline soda lakes, and other hypersaline environments worldwide. Each chapter contains an extensive list of references. No other book provides in-depth up-to-date coverage of all subjects described. The volume is intended for researchers and students interested in microbial physiology, microbial ecology, environmental sciences, and extremophilic biotechnology.

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