Adenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy
by David T. Curiel (Editor), Joanne T. Douglas (Editor)

Product Details:
* Hardcover: 890 pages
* Publisher: Academic Press; 1st edition (May 2002)
* Language: English
* ISBN-10: 0121995046

Book Description:
Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors.
Key Features
* Provides complete coverage of basic biology of adenoviruses, as well as the construction, propagation and purification of adenoviral vectors
* Introduces common strategies for the development of adenoviral vectors along with cutting-edge methods for their improvement
* Demonstrates noninvasive imaging of adenovirus-mediated gene transfer
* Discusses utility of adenoviral vectors in animal disease models
* Considers Federal Drug Administration regulations for human clinical trials

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Parasitic Nematodes

Parasitic Nematodes: Molecular Biology, Biochemistry and Immunology
by M. W. Kennedy (Editor), W. Harnett (Editor)

Product Details:
* Hardcover: 512 pages
* Publisher: CABI Publishing (February 15, 2001)
* Language: English
* ISBN-10: 0851994237

Book Description:
Currently more than one third of the world's population are infected with parasitic nematodes and infection of domestic animals remains a substantial drain on human well-being and economies. An understanding of the structure and function of genes, membrane and antigens of parasitic nematodes will help develop strategies to eliminate them or reduce their impact. This book outlines the advances made in this rapidly expanding research area.

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World of Microbiology and Immunology

World of Microbiology and Immunology
by K. Lee Lerner (Editor), Brenda Wilmoth Lerner (Editor)

Product Details:
* Hardcover: 699 pages
* Publisher: Thomson Gale (November 2002)
* Language: English
* ISBN-10: 0787665401

Book Description:
Microbiology and immunology are sometimes seen as esoteric and highly specialized sciences with few interpreters to students and the lay public. The authors have selected 600 entries that highlight selected important persons, research facilities, terms, and concepts of both these fields. There are brief biographies of the well known (Salk, Jonas) and the lesser known but important (Mil stein, Cesar); and explanations of common terms (Epidemics and pandemics), uncommon terms (Retroposons and transposable elements), and acronyms like AIDS and SCID (Severe combined immunodeficiency).

The entries are in alphabetical order with many cross references. Though there are no bibliographies with the entries, there are 13 pages of book and journal-article citations and 10 pages of Web addresses in the "Sources Consulted" section. This is followed by an 18-page "Historical Chronology" of milestones in human scientific achievement, showing how ancient (circa 10,000 B.C.E.) ideas eventually led to germ theory and the burgeoning of microbiology and immunology through 2002. The extensive, detailed general index indicates the main entries' volume and page numbers in boldface type. Sometimes the same page information is repeated in regular type, an unnecessary redundancy. Using the index one can find that the Irish potato famine is mentioned in the entry on Fungal genetics along with other similarly embedded bits of information. One important, but missing, finding aid is an index to the biographies, as browsing biographies is often a way to interest students in a discipline.

The language is straightforward and only as technical as required. The aim is to increase curiosity and interest in these diverse and important disciplines, and to show the development and growing importance of both fields to human health. Though the editors emphasize student use, the major users will probably be persons wanting to learn a bit about terms they hear or read in scientific and medical news. In no way does this publication compete with professional encyclopedias designed for researchers and medical practitioners such as Encyclopedia of Microbiology (Academic, 2000) or Encyclopedia of Immunology (Academic, 1998). Recommended for public libraries and general interest in academic libraries.

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