Gut Flora, Nutrition and Immunity

Gut Flora, Nutrition and Immunity [ILLUSTRATED]
by R. Fuller (Editor), G. Perdigon (Editor)

Product Details:
* Hardcover: 288 pages
* Publisher: Blackwell Publishing, Incorporated (June 1, 2003)
* Language: English
* ISBN-10: 1405100001

Book Description
Some foods, as well as contributing essential nutrients to the body, also contain additional components that improve disease resistance and general health status over and above that induced by ingestion of conventional foods. The so-called functional foods, and prebiotics and probiotics exemplify the relationship that exists between nutrition, the gut (the largest element of the body's immune system) and its flora, immunology and health.This important book contains chapters covering the basic principles of nutrition, gut microecology and immunology, as well as chapters which discuss the way in which this knowledge may be used to explain the positive and negative effects of food consumption, metabolism, probiotics and prebiotics. Food hypersensitivity and allergic reactions, carcinogenesis, and the role of nutrition in the reduced immunity of the aged are also discussed in detail.The editors of this exciting and informative book, who between them have a vast wealth of knowledge of the area, have drawn together and carefully edited international contributions from many well known and respected workers in the area. Gut Flora, Nutrition, Immunity and Health provides essential information for a range of professionals including nutritionists, dietitians, food scientists, microbiologists, gastroenterologists, immunologists and all personnel working in the development and use of functional foods and supplements, prebiotics and probiotics. Libraries in universities and research establishments where these subjects are studied and taught, and pharmaceutical and food companies should have multiple copies of this very useful book on their shelves.Roy Fuller is a consultant in gut microecology, based in Reading, UK; Gabriela Perdigón is based at the Centro de Referencia para Lactobacillus (CERELA) and at the Faculty of Biochemistry, Chemistry and Pharmacy of Tucuman University, Argentina.

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Gastroenteritis Viruses

Gastroenteritis Viruses
by Novartis Foundation (Author)

Product Details:
* Hardcover: 323 pages
* Publisher: Wiley; 1st edition (June 15, 2001)
* Language: English
* ISBN-10: 0471496634

Book Description
This important book covers the structure and molecular biology of small round structured viruses (SSRVs) such as caliciviruses and astroviruses, and the basic pathology of infection. It provides readers with the knowledge needed to make progress in the prevention and treatment of these infections. Readers will also find an overview of gastroentitis vaccines, their structure and molecular biology, as well as the basic pathology of infection, epidemiology and surveillance.
* Provides an interdisciplinary approach, offering contributions from basic and clinical research
* Discusses the prevention and treatment of regimes
* Includes an overview of gastroentitis vaccines

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Vaccines: From Concept to Clinic

Vaccines: From Concept to Clinic: A Guide to the Development and Clinical Testing of Vaccines for Human Use
by Lawrence C. Paoletti (Editor), Pamela McInnes (Editor)

Product Details:
* Hardcover: 224 pages
* Publisher: Informa Healthcare (July 29, 1998)
* Language: English
* ISBN-10: 0849311683

Book Description:
Designed with academic vaccine researchers in mind, this book presents a road map of how a vaccine develps from an idea in a researcher's imagination, to the lab bench, through preclinical evaluation, into the clinic for safety immunogenicity and efficacy, and ultimately to commercialization as a licensed product. Answers are provided to researcher questions such as:

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Toxocara: The Enigmatic Parasite

Toxocara: The Enigmatic Parasite
by C. V. Holland (Editor), H. V. Smith (Editor)

Product Details:
* Hardcover: 352 pages
* Publisher: CABI Publishing (March 27, 2006)
* Language: English
* ISBN-10: 1845930266

Book Description
Toxocara is a parasitic helminth worm, which continues to stimulate both public concern and scientific interest. toxocara canis and T. Cati are gastrointestinal parasites of dogs and cats and their eggs can contaminate the environment, thus exposing humans and other mammals and birds to infection. Many questions remain about the host-parasite relationship, it's epidemiology and public health significance. Veterinarians and clinicians are interested in its importance as a zoonosis and the parasite's capacity to enter the human eyes is of concern to opthamologists. This book provides a comprehensive review of toxocara and the disease it causes known as toxocariasis.

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Communicable Disease Control in Emergencies: A Field Manual

Communicable Disease Control in Emergencies: A Field Manual
by M. A. Connolly (Editor)

Product Details:
* Paperback: 295 pages
* Publisher: World Health Organization; 1st edition (February 28, 2006)
* Language: English
* ISBN-10: 9241546166

Book Description
This field manual is intended to help health professionals and public health coordinators working in emergency situations prevent, detect and control the major communicable diseases encountered by affected populations. The manual is the result of collaboration among a number of WHO departments and several external partner agencies in reviewing existing guidelines on communicable disease control and adapting them to emergency situations.

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The Anthrax Vaccine: Is It Safe? Does It Work?

The Anthrax Vaccine: Is It Safe? Does It Work?
by Lois M. Joellenbeck (Editor), Lee L. Zwanziger (Editor), Jane S. Durch (Editor), Brian L. Strom (Editor)

Product Details:
* Paperback: 288 pages
* Publisher: National Academy Press (May 2002)
* Language: English
* ISBN-10: 0309083095

Book Description:
Summary of the Committee to Assess the Safety and Efficacy of the Anthrax Vaccine which was congressionally mandated for the Department of Defense. Committee reviewed data and assessed the efforts to resolve manufacturing issues and resume production and distribution of the vaccine.

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Malaria: Drugs, Disease and Post-genomic Biology

Malaria: Drugs, Disease and Post-genomic Biology (Current Topics in Microbiology and Immunology)
by David Sullivan (Editor), Sanjeev Krishna (Editor)

Product Details:
* Hardcover: 444 pages
* Publisher: Springer; 1 edition (September 29, 2005)
* Language: English
* ISBN-10: 3540253637

Book Description
Despite rapid increases in knowledge, malaria continues to kill more than a million people each year and causes symptomatic disease in a further 300 million individuals. This volume brings some of the world's best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two.

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Immunotherapy for Infectious Diseases

Immunotherapy for Infectious Diseases (Infectious Disease)
by Jeffrey M. Jacobson (Editor)

Product Details
* Hardcover: 344 pages
* Publisher: Humana Press; 1 edition (June 15, 2002)
* Language: English
* ISBN-10: 0896036693

Book Description
In Immunotherapy for Infectious Disease, Jeffrey M. Jacobson, MD, and a panel of leading researchers review the state-of-the-art for treating various infections-particularly HIV-by manipulating the immune system's response rather than by chemical drugs. The contributors synthesize the principles of immune defense on the molecular level (monoclonal antibodies, vaccines, methods of antigen presentation, and cytokines and cytokine antagonists), as well as on the cellular and clinical levels levels as a protection against infection. The review of the current state of anti-HIV immunotherapy covers HIV-specific passive and active immunization strategies, gene therapy, and host cell-targeted approaches for treating HIV infection and restoring immune function.

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Immune Mechanisms of Pain and Analgesia

Immune Mechanisms of Pain and Analgesia (Advances in Experimental Medicine and Biology)
by Halina Machelska (Editor), Christoph Stein (Editor)

Product Details:
* Hardcover: 166 pages
* Publisher: Springer; 1 edition (January 31, 2003)
* Language: English
* ISBN-10: 0306476924

Book Description
Immune Mechanisms of Pain and Analgesia is the first volume to discuss a new concept of immune-neural interplays leading to pain or analgesia. It argues the classical view that pain and its control are restricted to the nervous system, offering a comprehensive overview of the emerging area of immune mechanisms in pain and its control. It challenges the traditional view that pain sensation or suppression is attributed exclusively to the nervous system and presents a critical analysis of this new concept. The book is written by an internationally recognized group of researchers and discusses complex and controversial issues such as cytokines and their pain-exacerbating but also analgesic effects, the production of opioids by immune cells, peripheral analgesic and anti-inflammatory actions of opioids, immunomodulatory effects of opiates, and immunosuppressive effects of pain.

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Color Atlas of Infective Endocarditis

Color Atlas of Infective Endocarditis
by David R. Ramsdale (Author)

Product Details:
* Hardcover: 154 pages
* Publisher: Springer; 1 edition (December 16, 2005)
* Language: English
* ISBN-10: 1852339373

Book Description
Infective endocarditis is a condition that still carries a high morbidity and mortality rate (20-30%) despite modern antibiotics and surgical treatment. The infection, usually caused by bacteria, invades the innermost lining of the heart and can damage heart valves, connective tissue and the heart chambers themselves. Rapid diagnosis, effective treatment, and prompt recognition of complications are essential to good patient outcome. If untreated, mortality is extremely high. The prevalence of infective endocarditis is between 1.7 and 4 people per 100,000, and is most commonly found in people who have underlying heart disease. Symptoms can be as non-specific as fever, fatigue, weight loss, new rashes (either painful or painless), headaches, backaches, joint pains and confusion; hence the disease remains a diagnostic and therapeutic challenge. Effective therapy has become progressively more difficult to achieve because of the proliferation of implanted biomechanical devices and the rise in the number of resistant organisms.

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The Prokaryotes: A Handbook on the Biology of Bacteria:Volume 1: Symbiotic Associations, Biotechnology, Applied Microbiology

The Prokaryotes: A Handbook on the Biology of Bacteria:Volume 1: Symbiotic Associations, Biotechnology, Applied Microbiology
by Martin Dworkin (Editor), Stanley Falkow (Editor), Eugene Rosenberg (Editor), Karl-Heinz Schleifer (Editor), Erko Stackebrandt (Editor)

Product Details:
* Hardcover: 959 pages
* Publisher: Springer; 3 edition (July 13, 2006)
* Language: English
* ISBN-10: 0387254765

Book Description
The first edition of The Prokaryotes, published in 1981, took a bold step to become the most comprehensive and authoritative encyclopedic handbook on prokaryotes. Another important step was taken with the second edition in 1992, when the chapters were organized on the basis of the molecular phylogeny as a rational, evolutionary basis for the taxonomy of the prokaryotes. By then, the two volumes of the first edition had expanded to four.
With the decision to publish the handbook electronically, the third edition was the boldest step of all. The advantages were obvious and persuasive: essentially unlimited space, no restrictions on the use of color, and the inclusion of film and animated illustrations. Nevertheless, the affection for a printed handbook was highly underestimated and during the first 5 years of the continuously evolving online version, a growing demand for a new print edition was voiced by the scientific and corporate community.
Thus, Springer is now publishing a third edition in printed form. In total, 7 volumes will make up this new fully revised and updated version. Compared to the second edition, this edition will contain 85% new contents, printed in color throughout. It will be ideally suited for research centers in academia and in the corporate world that need reliable and up-to-date information on the biology of the prokaryotic organisms.

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Immunobiology of Natural Killer Cell Receptors

Immunobiology of Natural Killer Cell Receptors (Current Topics in Microbiology and Immunology)
by Eric Vivier (Editor), Marco Colonna (Editor)

Product Details:
* Hardcover: 286 pages
* Publisher: Springer; 1 edition (December 1, 2005)
* Language: English
* ISBN-10: 3540260838

Book Description
Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.

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Infectious Diseases and Substance Abuse

Infectious Diseases and Substance Abuse (Infectious Agents and Pathogenesis)
by Herman Friedman (Editor), Thomas W. Klein (Editor), Mauro Bendinelli (Editor)

Product Details:
* Hardcover: 211 pages
* Publisher: Springer; 1 edition (August 26, 2005)
* Language: English
* ISBN-10: 0306486873

Book Description:
The influence of many drugs of abuse – licit and illicit – on immune function has been examined extensively in recent years. Many such substances, including marijuana, cocaine, morphine, and nicotine, have been shown to enhance the disease process by impairing immunologic function. Use of these drugs impairs immunologic functions by suppressing antibody function, decreasing cytokine production, enhancing production and release of IL1, and suppressing IL2 and interferon. Among the viruses known to be effected by these drugs are viruses such as herpes simplex virus and murine retrovirus and bacterial agents such as Staphylococcus, Listeria, Treponema, and Legionella.

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Bacterial Pathogenesis, Part B: Interaction of Pathogenic Bacteria with Host Cells

Methods in Enzymology, Volume 236: Bacterial Pathogenesis, Part B: Interaction of Pathogenic Bacteria with Host Cells (Methods in Enzymology)
by John N. Abelson (Editor), Melvin I. Simon (Editor), Virginia L. Clark (Editor), Patrik M. Bavoil (Editor)

Product Details:
* Hardcover: 642 pages
* Publisher: Academic Press; 1st edition (July 15, 1994)
* Language: English
* ISBN-10: 0121821374

Book Description:
The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced.

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Bacterial Pathogenesis, Part A: Identification and Regulation of Virulence Factors

Methods in Enzymology, Volume 235: Bacterial Pathogenesis, Part A: Identification and Regulation of Virulence Factors (Methods in Enzymology)
by John N. Abelson (Editor), Melvin I. Simon (Editor), Virginia L. Clark (Editor), Patrik M. Bavoil (Editor)

Product Details:
* Hardcover: 789 pages
* Publisher: Academic Press; 1st edition (May 15, 1994)
* Language: English
* ISBN-10: 0121821366

Book Description:
The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced.

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Retroviruses and Primate Genome Evolution

Retroviruses and Primate Genome Evolution (Molecular Biology Intelligence Unit)
by Eugene D. Sverdlov (Editor)

Product Details:
* Hardcover: 250 pages
* Publisher: Landes Bioscience (January 10, 2005)
* Language: English
* ISBN-10: 1587062135

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Pharmaceutical Microbiology

Pharmaceutical Microbiology
by W. B. Hugo (Editor), A. D. Russell (Editor)

Product Details:
* Paperback: 510 pages
* Publisher: Blackwell Science; 6th edition (July 15, 1998)
* Language: English
* ISBN-10: 063204196X

Book Description:
Formerly Univ. of Nottingham, UK. Text for pharmacy undergraduate students on microbiology as it relates to pharmacy, such as mode of action of antibiotics or the manufacture and quality control of pharmaceutical agents. Previous edition: c1992. Halftone illustrations.

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Fungal Immunology:: From an Organ Perspective

Fungal Immunology:: From an Organ Perspective
by Jr., Paul L. Fidel (Editor), Gary B. Huffnagle (Editor)

Product Details:
* Hardcover: 496 pages
* Publisher: Springer; 1 edition (June 6, 2005)
* Language: English
* ISBN-10: 0387240926

Book Description
Fungal immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurrence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases. This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi. Organization by body system rather than fungi is important because one particular fungus can have a different effect on defense mechanisms in different parts of the body.

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Phase Microscopy Principles and Applications

Phase Microscopy Principles and Applications
by Alva H. Bennett (Author)

Product Details
* Hardcover
* Publisher: John Wiley & Sons, Inc. (1951)
* ASIN: B000MA165G

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Tropical Infectious Diseases: Principles, Pathogens & Practice

Tropical Infectious Diseases: Principles, Pathogens & Practice( 2 Volume Set)
by Richard L. Guerrant (Author), David H. Walker (Author), Peter F. Weller (Author)

Product Details:
* Hardcover: 1936 pages
* Publisher: Churchill Livingstone; 2 edition (December 19, 2005)
* Language: English
* ISBN-10: 044306668X

Book Description
The reference JAMA called an outstanding contribution and must reading is back in a fully revised New Edition! This 2-volume set presents cutting-edge discussions of scientific principles, pathogenesis, pathophys-iology, diagnosis, treatment, and prevention for the full range of tropical infectious diseases. A new bonus CD-ROM, a clinical-focused organization, standardized life-cycle diagrams, and 850 illustrations make vital guidance easy to find and apply.

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Lentivirus Gene Engineering Protocols

Lentivirus Gene Engineering Protocols (Methods in Molecular Biology)
by Maurizio Federico (Editor)

Product Details:
* Hardcover: 328 pages
* Publisher: Humana Press; 1 edition (April 30, 2003)
* Language: English
* ISBN-10: 1588290913

Book Description
Maurizio Federico has assembled a panel of outstanding experimenters to detail all the theoretical and practical aspects of lentivirus vector-based gene transfer. The authors demonstrate lentivirus vector production with methods for recovering appropriate producer cells, for producing and titrating lentivirus-containing supernatants, and for detecting transduced cells. The applications of lentivirus vector engineering to different cell types include coverage of lymphocytes, dendritic cells, hematopoietic stem and progenitor cells, mesenchymal stem cells, hippocampal neurons, cardiomyocytes, as well as airway epithelia, corneal cells, and retinal pigment. Also advanced are applications in which genetic material is directly inoculated with lentivirus vectors in such experimental animal models as mouse, rat, and rabbit.

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Keys to the Trematoda

Keys to the Trematoda
by D. J. Gibson (Editor), R. A. Bray (Editor), A. Jones (Editor)

Product Details
* Hardcover: 500 pages
* Publisher: CABI Publishing (June 15, 2007)
* Language: English
* ISBN-10: 0851995888

Book Description
This book, in three volumes, presents a detailed revision of the systematics and taxonomy of the platyhelminth class Trematoda, subclasses Aspidogastrea and Digenea, with keys for the identification of these parasites at the superfamily, family, subfamily and generic levels. The trematodes are parasitic worms infecting all vertebrate groups and include families of significance to human and animal health, with considerable economic impact. The first volume covers the subclass Aspidogastrea and order Strigeida, while the second and third volumes cover the orders Echinostomida and Plagiorchiida.

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Tuberculosis and Nontuberculosis Mycobacterial Infections

Tuberculosis and Nontuberculosis Mycobacterial Infections
by David Schlossberg (Author)

Product Details
* Hardcover: 400 pages
* Publisher: McGraw-Hill Professional; 5 edition (December 16, 2005)
* Language: English
* ISBN-10: 0071439137

Book Description
The Definitive Text on Tuberculosis Infections for More Than Two Decades!
This trusted resource provides infectious disease specialists with the most comprehensive coverage found anywhere of the varied manifestations of tuberculin diseases and the clinical options available to physicians for treating them. The new edition has been updated to reflect state-of-the-art changes in the direction and management of these diseases and contains new chapters on multi-drug resistance and the latest prophylactic strategies.

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Cytokine Molecular Biology

Cytokine Molecular Biology: A Practical Approach
by Fran Balkwill (Editor)

Product Details
* Paperback: 201 pages
* Publisher: Oxford University Press, USA; 3rd edition (December 15, 2000)
* Language: English
* ISBN-10: 0199638578

Book Description
Cytokine Molecular Biology concentrates on molecular biology techniques for the study of cytokines, cytokine receptors, and cytokine driven processes. Updated topics from the previous edition are: the cloning and expressing cytokine genes;; the detection of cytokine mRNA; receptor binding studies; the PC-specific phosphslipase C and sphingomylinases. In addition, new topics covered are the purification, sequencing, and synthesis of cytokines; studying cytokine gene polymorphisms; the use of proteomics in cytokine research; and the Jak/STAT and MAPK signalling pathways. Written by experts in the field, Cytokine Molecular Biology and Cytokine Cellular Biology form a comprehensive and essential guide to cytokine research.

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Molecular Biology of B Cells

Molecular Biology of B Cells
by Tasuku Honjo (Editor), Frederick W. Alt (Editor), Michael Neuberger (Editor)

Book Description
Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.

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Killer Cell Dynamics

Killer Cell Dynamics: Mathematical and Computational Approaches to Immunology (Interdisciplinary Applied Mathematics)
by Dominik Wodarz (Author)

Product Details:
* Hardcover: 226 pages
* Publisher: Springer; 1 edition (November 30, 2006)
* Language: English
* ISBN-10: 0387308938

Book Description
This book reviews how mathematics can be used in combination with biological data in order to improve understanding of how the immune system works. This is illustrated largely in the context of viral infections. Mathematical models allow scientists to capture complex biological interactions in a clear mathematical language and to follow them to their precise logical conclusions. This can give rise to counter-intuitive insights which would not be attained by experiments alone, and can be used for the design of further experiments in order to address the mathematical results.
This book provides both an introduction to the field of mathematical immunology, and an overview of many topics which are the subject of current research, covering a broad variety of immunological topics. It starts with basic principles of immunology and covers the dynamical interactions between the immune system and specific viral infections, including important human pathogens such as HIV. General biological and mathematical background material to both virus infection and immune system dynamics is provided, and each chapter begins with a simple introduction to the biological questions examined.
This book is intended for an interdisciplinary audience. It explains the concept of mathematical modeling in immunology and shows how modeling has been used to address specific questions. It is intended both for the mathematical biologists who are interested in immunology, and for the biological readership that is interested in the use of mathematical models in immunology. Dominik Wodarz is an Associate Professor at the Department of Ecology and Evolutionary Biology at the University of California, Irvine.

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Bacterial Artificial Chromosomes: Volume 2: Functional Studies

Bacterial Artificial Chromosomes: Volume 2: Functional Studies (Methods in Molecular Biology)
by Shaying Zhao (Editor), Marvin Stodolsky (Editor)

Product Details:
* Hardcover: 344 pages
* Publisher: Humana Press; 1 edition (March 4, 2004)
* Language: English
* ISBN-10: 0896039897

Book Description
Expert investigators describe not only the classic methods, but also the many novel techniques they have perfected for the transfer of large DNAs into the cells of both microbes and animals via large-insert recombinant DNAs. Volume 1 presents readily reproducible techniques for library construction, physical mapping, and sequencing.. An accompanying volume, Volume 2: Functional Studies, provides a wide variety of methods and applications for functional analysis of the DNA-transformed organisms. Besides protocols, each chapter includes scientific reviews, software tools, database resources, genome sequencing strategies, and illustrative case studies.

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Escherichia Coli 0157:H7 in Ground Beef: Review of a Draft Risk Assessment

Escherichia Coli 0157:H7 in Ground Beef: Review of a Draft Risk Assessment
by Institute of Medicine (Author)

Product Details
* Paperback: 172 pages
* Publisher: National Academy Press (December 2002)
* Language: English
* ISBN-10: 0309086272

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Antibiotic Policies: Fighting Resistance

Antibiotic Policies: Fighting Resistance
by Ian M. Gould (Editor), Jos W.M. van der Meer (Editor)

Product Details:
* Hardcover: 462 pages
* Publisher: Springer; 1 edition (August 24, 2007)
* Language: English
* ISBN-10: 0387708405

Book Description:
This volume continues the tradition of the editors' first volume, Antibiotic Policies: Theory and Practice, by assembling contributions from experts around the world concerned with responsible antibiotic resistance and fighting resistance. This volume looks at many of the crucial issues of resistance in a clinical context, with an emphasis on MRSA; surely the greatest challenge to our antibiotic and infection control policies that modern health care systems have ever seen. Other fascinating chapters explore the psychology of prescribing, modern management techniques as an adjunct to antibiotic policies, and the less obvious downsides of antibiotic use. Lastly, several chapters from authors living in Mediterranean countries give a perspective from an area of the world with some of the greatest problems in antibiotic use and resistance.

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New Concepts of Antiviral Therapy

New Concepts of Antiviral Therapy
by Elke Bogner (Editor), Andreas Holzenburg (Editor)

Product Details:
* Hardcover: 538 pages
* Publisher: Springer; 1 edition (June 2, 2006)
* Language: English
* ISBN-10: 0387310460

Book Description:
Antiviral drugs are important tools for treatment or prevention of viral infections. These drugs were first used for monotherapy, but nowadays combinations of antiviral agents are often part of a standard treatment as evidenced by e.g. HAART (highly active antiretroviral therapy). However, in almost every case of antiviral therapy, drug resistant viruses appear. In addition, the low oral bioavailability, toxicity and the number of severe side effects still pose significant problems. All of the latter issues limit the clinical usefulness and drive the need for improved antiviral strategies. These strategies include new drugs and targets, novel modes of action, vector-based treatments and even the block of defined genes by inhibiting mRNA formation (siRNA).
Highlights of this book include the discussion of:
- novel, promising compounds
- concepts of therapy for new/emerging viruses
- managing drug resistance
- new therapeutic strategies
This book presents an overview of the most recent developments. Contributions were carefully selected to ensure quality coverage by acknowledged experts over a wide spectrum and should prove to be of great value to students and serve as a compendium for R and D and educational professionals.

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Cardiovascular Disease in AIDS

Cardiovascular Disease in AIDS
by Giuseppe Barbaro (Editor), Franck Boccara (Editor), Giorgio Barbarini (Editor)

Product Details:
* Paperback: 169 pages
* Publisher: Springer; 1 edition (April 6, 2005)
* Language: English
* ISBN-10: 8847003091

Book Description:

Studies published before the introduction of highly active antiretroviral therapy (HAART) tracked the incidence and course of HIV infection in relation to cardiac illness in both children and adults. These studies show that subclinical echocardiographic abnormalities independently predict adverse outcomes and identify high-risk groups to be targeted for early intervention and therapy. The introduction of HAART has altered cardiovascular manifestations in HIV. On the one hand, HAART has significantly modified the course of HIV disease, lengthened survival, and improved the quality of life of HIV-infected patients. On the other hand, the early data have raised concerns that HAART is associated with an increase in both peripheral and coronary arterial diseases, creating an intriguing clinical scenery. This book focuses on new clinical and biological insight related to HIV-associated metabolic and cardiovascular complications in the HAART era.

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Microorganisms in Foods 6: Microbial Ecology of Food Commodities

Microorganisms in Foods 6: Microbial Ecology of Food Commodities (Microorganisms in Foods)
by International Commission on Microbiological Specifications of Foods (ICMSF) (Author)

Product Details:
* Hardcover: 736 pages
* Publisher: Springer; 2 edition (July 1, 2005)
* Language: English
* ISBN-10: 030648675

Book Description:
The second edition of Microorganisms in Foods 6: Microbial Ecology of Food Commodities is for those primarily interested in applied aspects of food microbiology. For 17 commodity areas, it describes the initial microbial flora and the prevalence of pathogens, the microbiological consequences of processing, typical spoilage patterns, episodes implicating those commodities with foodborne illness, and measures to control pathogens and limit spoilage. Those control measures are presented in a standardized format in line with international developments in risk management; a comprehensive index has also been added in this fully revised and much-anticipated edition.

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Bacterial and Bacteriophage Genetics

Bacterial and Bacteriophage Genetics
by Edward A. Birge (Author)

Product Details:
* Hardcover: 580 pages
* Publisher: Springer; 5 edition (December 8, 2005)
* Language: English
* ISBN-10: 0387239197

Book Description
Genetic investigations and manipulations of bacteria and bacteriophage have made vital contributions to our basic understanding of living cells and to the development of molecular biology and biotechnology. This volume is a survey of the genetics of bacteria and their viruses, and it provides students with a comprehensive introduction to this rapidly changing subject. The book is written for upper level undergraduates and beginning graduate students, particularly those who have had an introductory genetics course. The fifth edition has been extensively revised to reflect recent advances in the field. The book now has a reader-friendly look, with end-of-chapter questions, "Thinking Ahead" and "Applications" boxes to challenge students’ comprehension and insights. A complete glossary of commonly used terms has been revised and expanded.

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E. coli Plasmid Vectors

E. coli Plasmid Vectors: Methods and Applications (Methods in Molecular Biology)
by Nicola Casali (Editor), Andrew Preston (Editor)

Product Details:
* Hardcover: 328 pages
* Publisher: Humana Press; 1 edition (July 3, 2003)
* Language: English
* ISBN-10: 1588291510

Book Description
A comprehensive collection of readily reproducible techniques for the manipulation of recombinant plasmids using the bacterial host E. coli. The authors describe proven methods for cloning DNA into plasmid vectors, transforming plasmids into E. coli, and analyzing recombinant clones. They also include protocols for the construction and screening of libraries, as well as specific techniques for specialized cloning vehicles, such as cosmids, bacterial artificial chromosomes, l vectors, and phagemids. Common downstream applications such as mutagenesis of plasmids, recombinant protein expression, and the use of reporter genes, are also described.

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Horizontal Gene Pool: Bacterial Plasmids and Gene Spread

Horizontal Gene Pool: Bacterial Plasmids and Gene Spread
by Christopher M. Thomas (Author)

Product Details;
* Hardcover: 444 pages
* Publisher: CRC (May 1, 2000)
* Language: English
* ISBN-10: 9057024624

Book Description
Bacteria are the most ubiquitous of all organisms. Responsible for several diseases and for many of the chemical cycles on which life depends, they are genetically adaptable. Vital to this adaptability is the existence of autonomous genetic elements-plasmids-which promote genetic exchange and recombination. The genes carried by any particular plasmid may be found in only a few individuals of any species but can also be shared with other species and thus constitute a horizontal gene pool. This book explains plasmids in this pool: the replication, the phenotypic markers they carry, the way they evolve, the ways they contribute to their host population and the approaches used to study and classify them.

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Fungal Genomics

Fungal Genomics (The Mycota)
by A.J.P. Brown (Editor)

Product Details:
* Hardcover: 276 pages
* Publisher: Springer; 1 edition (December 16, 2005)
* Language: English
* ISBN-10: 354025594X

Book Description
Through the integration of bioinformatic, genetic, transcriptomic, proteomic, metabolomic, phenomic and other massive datasets, genomics is revealing exciting new insights into fungal cell biology. The central theme of this volume is the strong impact that genomics is having upon our understanding of fungal biology, across a wide range of species, including model yeasts (such as Saccharomyces cerevisiae and Schizosaccharomyces pombe), filamentous fungi (such as Neurospora crassa and Aspergillus nidulans) and pathogenic fungi (such as Magnaporthe grisae, Candida albicans, Cryptococcus neoformans and Histoplasma capsulatum). World-renowned scientists address the following topics in these fungi: systems biology and evolution, circadian rhythms, apoptosis and stress responses, secretion, and environmental signalling networks. Particular emphasis is placed on fungal pathogenicity. Various genomic technologies are discussed, including genome-wide sequence comparisons, transcript profiling, proteomics, metabolomics and bioinformatic

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Molecular Microbiology of Heavy Metals

Molecular Microbiology of Heavy Metals (Microbiology Monographs)
by Dietrich H. Nies (Editor), Simon Silver (Editor)

Product Details:
* Hardcover: 390 pages
* Publisher: Springer; 1 edition (May 2007)
* Language: English
* ISBN-10: 3540697705

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Multiplication of RNA Plant Viruses

Multiplication of RNA Plant Viruses
by C.L. Mandahar (Author)

Product Details:
* Hardcover: 339 pages
* Publisher: Springer; 1 edition (August 18, 2006)
* Language: English
* ISBN-10: 140204724X

Book Decription

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Kaposi Sarcoma Herpesvirus: New Perspectives

Kaposi Sarcoma Herpesvirus: New Perspectives (Current Topics in Microbiology and Immunology)
by C. Boshoff (Editor), R.A. Weiss (Editor)

Product Details:
* Hardcover: 332 pages
* Publisher: Springer; 1 edition (October 31, 2006)
* Language: English
* ISBN-10: 3540343431

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Essentials of Clinical Immunology

Essentials of Clinical Immunology [ILLUSTRATED]
by Helen Chapel (Author), Mansel Haeney (Author), Siraj Misbah (Author), Neil Snowden (Author)

Product Details:
* Paperback: 368 pages
* Publisher: Blackwell Publishing Limited; 5 edition (May 1, 2006)
* Language: English
* ISBN-10: 1405127619

Book Description
Essentials of Clinical Immunology is aimed at clinical medical students and trainee doctors, although it will also appeal to career grade doctors seeking a refresher in clinical immunology. The book provides the reader with the core information required to understand diseases that have an immunological basis. This includes coverage of the underlying pathophysiology and signs and symptoms of disease, as well as the special investigations required and management of patients. The book's emphasis is very much on the clinical aspects with numerous real life case histories used to illustrate key concepts throughout the text. The book also contains MCQs at the end of each chapter for self-assessment. There is an accompanying web site (www.immunologyclinic.com) which includes further case histories, references to further reading and a colour image archive.This new edition is fully updated and is now in full colour throughout improving the general presentation and usability of this core clinical immunology textbook.
Essential Clinical Immunology is aimed at clinical medical students and trainee doctors, although it will also appeal to medical professionals seeking a refresher in clinical immunology. The book provides the reader with the core information required to understand diseases with an immunological basis.This new edition of Essential Clinical Immunology is fully updated, now in full colour throughout and features:- coverage of the underlying pathophysiology and signs and symptoms of disease, as well as the special investigations required and management of patients;- emphasis on the clinical aspects with numerous real life case histories used to illustrate key concepts;- MCQs at the end of each chapter for self-assessment;- An accompanying web site, www.immunologyclinic.com, which includes further case histories, references to further reading and a colour image archive.Reviews from previous edition:"This is a very comprehensive book, and would serve postgraduates well in addition to students embarking on pathology...It is well written by people who know their subject well, and know what information it is important to convey...All the vital areas you might want to read up on are covered more than adequately."MAD,The Student Magazine for Medics & Dentists at Bart's and theLondon"Where this book shines is in its integrated approach regarding clinical topics. Each body system, along with specialist topics including transplantation and hypersensitivity has its own chapter, covering both common pathologies involving the immune system and the theory behind these...Well written, integrates clinical topics seamlessly. Case histories provide valuable insight, and self-assessment questions included at the end of each chapter."2nd Opinion,The Magazine of the Scottish Medical Schools"I think that this is the best of the bunch...much more relevant to our course and a sound investment for the future."Sphincter,LiverpoolMedical Students' Society Magazine

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Viral Transport in Plants

Viral Transport in Plants (Plant Cell Monographs)
by Elisabeth Waigmann (Editor), Manfred Heinlein (Editor)

Product Details:
* Hardcover: 180 pages
* Publisher: Springer; 1 edition (May 2007)
* Language: English
* ISBN-10: 3540698426

Book Description

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Plant-Associated Bacteria

Plant-Associated Bacteria
by Samuel S. Gnanamanickam (Editor)

Product Details:
* Hardcover: 724 pages
* Publisher: Springer; 1 edition (July 6, 2006)
* Language: English
* ISBN-10: 1402045360

Book Description
This volume is developed on the broad theme of plant-associated bacteria. It is envisioned as a resource volume for researchers working with beneficial and harmful groups of bacteria associated with crop plants. The book is divided into two parts. Part I (9 chapters) on beneficial bacteria includes chapters on symbiotic nitrogen fixers, diazotrophs, epiphytes, endophytes and rhizosphere bacteria and deleterious rhizobacteria. Part II (8 chapters) consists of detailed descriptions of 8 genera of plant pathogenic bacteria: Agrobacterium, Clavibacter, soft-rot Erwinia, Pseudomonas, Xanthomonas, Ralstonia, Burkholderia and Acidovorax and Herbaspirillum. There is an opening chapter on the plant-associated bacteria survey, molecular phylogeny, genomics and recent advances. And each chapter includes terminology/definitions, molecular phylogeny, methods that can be used (both traditional and latest molecular tools) and applications.

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Reoviruses: Entry, Assembly and Morphogenesis

Reoviruses: Entry, Assembly and Morphogenesis (Current Topics in Microbiology and Immunology)
by Polly Roy (Editor)

Product Details:
* Hardcover: 268 pages
* Publisher: Springer; 1 edition (June 2006)
* Language: English
* ISBN-10: 3540307729

Book Description
Mammalian reovirus had been the major focus for molecular understanding of the Reoviridae and has served as a model system for the other members of the family. Indeed, most of our initial understanding of molecular biology and processes involved in virus replication and pathogenesis for the members of the family was generated from reovirus studies. With this platform two other members of the family causing disease in human and/or animals have gained in prominence and the molecular interactions from a structural level through to host-virus interactions as well as the function of the structural and non-structural proteins in the virus life cycle has been investigated in detail. This book reviews our current understanding of Reoviridae entry, disassembly/assembly and egress in addition to updating high resolution structures of virus proteins and capsids from three different genera of the family.

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Hepatitis Delta Virus

Hepatitis Delta Virus (Current Topics in Microbiology and Immunology)
by J.L. Casey (Editor)

Product Details:
* Hardcover: 228 pages
* Publisher: Springer; 1 edition (June 14, 2006)
* Language: English
* ISBN-10: 3540298010

Book Description
Hepatitis delta virus which causes severe acute and chronic liver disease was discovered following the detection of a novel antigen-antibody system in hepatitis B virus carriers. Currently, HDV is classified as a subviral satellite of hepatitis B virus. However, unlike other satellite viruses, the dependence of HDV on HBV is limited solely to the provision of an envelope of hepatitis B surface antigen for virus assembly. Research into the molecular virology of the HDV life cycle has revealed a fascinating collection of biology. These insights are now beginning to be translated into new potential treatment strategies. There are currently still an estimated 15 million HDV carriers worldwide.

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