Applied Dairy Microbiology

Applied Dairy Microbiology, Second Edition, (Fos Food Science and Technology)
by Elmer H. Marth (Editor), James Steele (Editor)

Product Details;
* Hardcover: 736 pages
* Publisher: CRC; 2 edition (May 22, 2001)
* Language: English
* ISBN-10: 082470536X

Book Description:
The first book of its kind published in the United States since 1957, this comprehensive reference/text provides a thoroughly updated and expanded treatment of dairy microbiology from basic information on dairy foods to special topics, including the microbiology of milk-producing animals, probiotics, and conversion of whey into useful products. Applied Dairy Microbiology discusses the microbiology of the rumen and the role of microorganisms in milk synthesis explores the causes and contamination of raw milk by mastitis offers solutions to problems associated with raw milk, fluid milk products, concentrated and dried milk and whey, frozen dairy desserts, butter, other unfermented foods, in addition to fermented milks and cheese examines the genetics and metabolism of lactic acid bacteria as well as how they are used to produce fermented products emphasizes the importance of eliminating health concerns of salmonellosis, staphylococcal food poisoning, listeriosis, and other diseases introduces the Hazard Analysis and Critical Control Points (HACCP) approach to controlling pathogenic and spoilage microorganisms in dairy food processing features sampling and testing methods for assuring the quality and safety of milk products provides details on treating dairy wastes and complying with regulatory requirements and more! Containing over 1800 bibliographic citations, tables, drawings, and photographs, Applied Dairy Microbiology is an essential reference for food and dairy microbiologists, scientists, and technologists; quality control specialists; administrators of food and dairy programs in local, state, and federal regulatory agencies; dairy plant managers; ingredient suppliers to dairy industries; and veterinarians; as well as a lucid text for upper-level undergraduate and graduate students in these disciplines.

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Modern Food Microbiology

Modern Food Microbiology
by James M. Jay (Author)

Product Details:
* Hardcover: 720 pages
* Publisher: Springer; 6 edition (January 1, 2000)
* Language: English
* ISBN-10: 083421671X

Book Description
An Aspen Food Science Text Series Book. A new, sixth edition brings benefits to professors and students alike who will find new chapters on food preservation by modified atmosphere, high pressure and pulsed electric field processing, and foodborne pathogens; additional sections covering new food regulations, fresh-cut produce, new food products, and risk assessment and analysis; and thorough updating of taxonomies, text, illustrations, and references throughout. Coverage includes: historical background; overview of microorganisms in food and what allows them to grow; specific microorganisms in fresh, fermented, and processed meats, poultry, seafood, dairy products, fruits, vegetables, and other products; scientific methods for finding and measuring microorganisms and their products in foods; scientific methods for preserving foods; food safety and quality controls; foodborne diseases; and in-depth references following each chapter, appendixes, and index. A helpful Instructor's manual is available to adopting professors.

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Tuberculosis 2007

Tuberculosis 2007:From basic science to patient care

The book was published for the Amedeo Tuberculosis Textbook Award
(The winner of the award is a team of 40 clinicians and researches guided by
Juan Carlos Palomino, Sylvia Cardoso Leão, and Viviana Ritacco.
687 pages

Tuberculosis 2007 is a medical textbook that provides a comprehensive and up-to-date overview of research,
diagnosis and treatment of tuberculosis

contents:

1 History
2 Molecular Evolution of the Mycobacterium tuberculosis Complex
3 The Basics of Clinical Bacteriology
4 Genomics and Proteomics
5 Immunology, Pathogenesis, Virulence
6 Host Genetics and Susceptibility
7 Global Burden of Tuberculosis
8 Tuberculosis caused by Other Members of the M. tuberculosis Complex
9 Molecular Epidemiology: Breakthrough Achievements and Future Prospects
10 New Vaccines against Tuberculosis
11 Biosafety and Hospital Control
12 Conventional Diagnostic Methods
13 Immunological Diagnosis
14 New Diagnostic Methods
15 Tuberculosis in Adults
16 Tuberculosis in Children
17 Tuberculosis and HIV/AIDS
18 Drugs and Drug Interactions
19 Drug Resistance and Drug Resistance Detection
20 New Developments and Perspectives

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Biochemistry and Physiology of Anaerobic Bacteria

Biochemistry and Physiology of Anaerobic Bacteria
by Lars G. Ljungdahl (Editor), Michael W. Adams (Editor), Larry L. Barton (Editor), James G. Ferry (Editor), Michael K. Johnson (Editor)

Product Details:
* Hardcover: 272 pages
* Publisher: Springer; 1 edition (January 31, 2006)
* Language: English
* ISBN-10: 0387955925

Book Description
During the past twenty years, multitudes of exciting discoveries in the field of anaerobic bacteria have been made. BIOCHEMISTRY AND PHYSIOLOGY OF ANAEROBIC BACTERIA explores the full range of these microorganisms. Many anaerobes have been found to have the uniquely fascinating quality of being able to survive, indeed even thrive, in extreme environments. Anaerobic bacteria often do not require oxygen, can survive extremes in temperature, and can withstand the presence of toxins and heavy metals. In addition, these organisms have very different metabolic processes than "conventional" microorganisms. The wide diversity of metabolism in anaerobes is only part of the story. They have distinct energies, cytochromes, electron transport proteins, hydrogenases and dohydrogenases. Their molecular biology, physiology, and ability to use many types of electron receptors (CO2, sulfur, nitrogen and metal oxides) are also extraordinary. With practical applications ranging from wastewater treatment to food storage issues, clinical diagnosis and treatment of a wide range of medical conditions to decontamination of heavy metal exposures BIOCHEMISTRY AND PHYSIOLOGY OF ANAEROBIC BACTERIA will prove indispensable to researchers and students alike.

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Entomopathogenic Nematology

Entomopathogenic Nematology
by Randy Gaugler (Editor)

Product Details:
* Hardcover: 402 pages
* Publisher: CABI Publishing (March 11, 2002)
* Language: English
* ISBN-10: 0851995675

Book Description
Nematodes that are parasites of insects are no longer a laboratory curiosity. They have begun to be accepted as environmentally benign alternatives to the use of chemical insecticides, for the control of insect pests. Nematode worms are now applied as biological control agents against insect pests of numerous horticultural and agricultural crops. This book provides a comprehensive review of entomopathogenic nematology. It begins by reviewing fundamental biology and setting a taxonomic foundation for nematodes and their bacterial symbionts. Several chapters are devoted to functional processes involved in parasitism and to nematode ecology. Later chapters describe technological advances and control methodologies.

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Antigen Processing and Presentation Protocols

Antigen Processing and Presentation Protocols (Methods in Molecular Biology)
by Joyce C. Solheim (Editor)

Product Details:
* Hardcover: 281 pages
* Publisher: Humana Press; 1st edition (January 15, 2001)
* Language: English
* ISBN-10: 0896037452

Book Description
Well-recognized and innovative experimentalists detail their cutting-edge methods for studying the antigen processing and presentation. Drawing on expertise from biochemistry, cell biology, and immunology, they describe step-by-step methods designed to question how MHC-binding peptides are generated, to test how peptides are delivered to MHC molecules, to analyze MHC peptide-binding patterns, and to assay the T-cell response to the MHC/peptide complex. Emphasis is given those technical steps critical for experimental success that are often omitted from methods published in the primary literature. Eminently accessible and state-of-the-art, Antigen Processing and Presentation Protocols provides both new and experienced investigators with highly practical tools that will extend the questions that can be asked, and effectively be answered, concerning antigen processing/presentation.

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T Cell Activation by CD1 and Lipid Antigens

T Cell Activation by CD1 and Lipid Antigens (Current Topics in Microbiology and Immunology)
by Branch D. Moody (Editor)

Product Details:
* Hardcover: 290 pages
* Publisher: Springer; 1 edition (May 2007)
* Language: English
* ISBN-10: 3540695109

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Lactic Acid Bacteria: Microbiological and Functional Aspects

Lactic Acid Bacteria: Microbiological and Functional Aspects, Third Edition (Food Science and Technology)
by Seppo Salminen (Editor), Atte von Wright (Editor), Arthur C. Ouwehand (Editor)

Product Details
* Hardcover: 656 pages
* Publisher: CRC; 3 edition (July 23, 2004)
* Language: English
* ISBN-10: 0824753321

Book Description
With more than 25 percent new material, this third edition provides an excellent overview of current research on the function, utilization, and nutritional aspects of lactic acid bacteria. The book showcases the scientific, commercial, and technological findings of 37 international contributors that may impact the quality, taste, and dietary value of foods such as milk, cereal, vegetables, and meat. It contains new chapters ranging from topics on mathematical modeling and vegetable fermentation to techniques for the analysis of gut microbiota and probiotics for fish. It also features updated information of future research directions for the utilization of lactic acid bacteria.

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Rapid Review Microbiology and Immunology

Rapid Review Microbiology and Immunology (CD-ROM)
by Ken S. Rosenthal (Author), James S. Tan (Author)

Product Details:
* Paperback: 384 pages
* Publisher: Mosby; Bk&CD-Rom edition (May 7, 2002)
* Language: English
* ISBN-10: 0323008402

Book Description:
Northeastern Ohio Univ., Rootstown. Exam review, in outline format, includes two 50-question tests with rationales at the end of the book, high-yield margin notes, and a CD-ROM containing current USMLE-type questions and rationales.

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Laboratory Exercises To Accompany Microbiology

Laboratory Exercises To Accompany Microbiology
by John P Harley (Author), Lansing M. Prescott (Author), Lansing Prescott (Author)

Product Details:
* Spiral-bound: 480 pages
* Publisher: McGraw-Hill Science/Engineering/Math; 5 edition (August 13, 2001)
* Language: English
* ISBN-10: 0072333456

Book Description
Laboratory Exercises in Microbiology, 5/e has been prepared to accompany Prescott et al's Microbiology, 5/e. Like the text, the laboratory manual provides a balanced introduction to laboratory techniques and principles that are important in each area of microbiology.

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Molecular Mimicry: Infection Inducing Autoimmune Disease

Molecular Mimicry: Infection Inducing Autoimmune Disease (Current Topics in Microbiology and Immunology)
by Michael B.A. Oldstone (Editor)

Product Details:
* Hardcover: 168 pages
* Publisher: Springer; 1 edition (December 19, 2005)
* Language: English
* ISBN-10: 3540255974

Book Description
The conceptual basis for molecular mimicry was first defined in the early 1980s when monoclonal antibodies against viruses were also shown to react with non-viral host protein; in this case, measles virus phosphoprotein cross-reacted with host cell cytokeratin, herpes simplex virus type 1 with host-cell vimentin and vaccinia virus with host-cell intermediate filaments. Following this discovery, others emerged, again at the clonal level, that T cell clones against proteins from a variety of infectious agents also reacted with host antigenic determinants. The clonal distinction was imperative for the initial definition of mimicry. At least 30 years prior to our initial description of molecular mimicry involving cross-reactions between numerous microbes, on the polyclonal antibody level, streptococcus was believed to react with renal glomeruli, heart and basal ganglia to account for the glomerulonephritis, heart and valvular disease and chorea, respectively. However, subsequent research showed that the nephritis was caused by immune complex deposits and the tissue damage they produced. Later, in 1990, the cross-reactivity of streptococcal antigen with myocardial antigens on a clonal level was uncovered. Hence, for both historical reasons and mechanistic understanding, it is best to provide evidence for cross-reactivity at the clonal level to prove that molecular mimicry exists.

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Wine Microbiology: Practical Applications and Procedures

Wine Microbiology: Practical Applications and Procedures
by Kenneth C. Fugelsang (Author), Charles G. Edwards (Author)

Product Details:
* Hardcover: 396 pages
* Publisher: Springer; 2 edition (November 14, 2006)
* Language: English
* ISBN-10: 038733341X

Book Description
Since publication of the first edition of Wine Microbiology in 1997, the volume of new information and concepts has dramatically increased. Even with the tremendous increase in available information, a comprehensive understanding regarding the role of individual microorganisms towards wine quality as well as the impact of complicated interactions between microorganisms and processing techniques is lacking.
Wine Microbiology, Second Edition, fills this void. Like the first edition, the book addresses real world problems such as characterization and enumeration of yeast, bacteria and molds common to juice and wine environments and their impact on wine quality and stability. In addition, the potential of solving processing problems through rapid, real-time molecular methods and new applications for using starter cultures of non-Saccharomyces yeast are discussed. The book is a great resource for professionals and students in the field of enology and viticulture.

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Retroviral Proteases

Retroviral Proteases, Volume 241 (Methods in Enzymology)
by John N. Abelson (Editor), Melvin I. Simon (Editor), Lawrence C. Kuo (Editor), Jules A. Shafer (Editor)

Product Details:
* Hardcover: 432 pages
* Publisher: Academic Press (September 22, 1994)
* Language: English
* ISBN-10: 0121821420

Book Description:
The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced.

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RNA Viruses: A Practical Approach

RNA Viruses: A Practical Approach
by Alan J. Cann (Editor)

Product Details:
* Paperback: 266 pages
* Publisher: Oxford University Press, USA; 1st edition (May 15, 2000)
* Language: English
* ISBN-10: 0199637164

Book Description
RNA Viruses: A Practical Approach is wide ranging in scope, from emerging technology such as reverse genetics and retrovirus vectors, to money saving tips - how to make your own silica particles for high efficiency RNA extraction and liposomes for cell transfection! Chapter One covers the fundamentals of investigating RNA virus genome structure at a molecular level. Chapters Two and Three describe techniques for mutagenesis of RNA genomes and analysis of transcription. Chapter Four deals with RNA virus-encoded proteinases, an important aspect of the control of RNA virus gene expression. Chapter Five considers retrovirus oncogenesis and Chapter Six analysis of RNA virus quasispecies. Chapter Seven describes systems for investigation of in vitro replication of positive-stranded viruses and chapter eight the packaging of RNA virus genomes. In addition to the technical aspects of reverse genetics and retrovirus vectors, both of the final two chapters also consider ethical aspects of these new technologies.

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Community-Acquired Pneumonia

Community-Acquired Pneumonia (Birkhäuser Advances in Infectious Diseases)
by Norbert Suttorp (Editor), Tobias Welte (Editor), Reinhard Marre (Editor)

Product Details:
* Hardcover: 250 pages
* Publisher: Birkhäuser Basel; 1 edition (January 2007)
* Language: English
* ISBN-10: 3764375620

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Environmental Microbiology, Volume 397

Environmental Microbiology, Volume 397 (Methods in Enzymology)
by Jared Leadbetter (Editor)

Product Details:
* Hardcover: 568 pages
* Publisher: Academic Press (August 1, 2005)
* Language: English
* ISBN-10: 0121828026

Book Description
Environmental Microbiology covers cultivation of diverse microbes, physiological ecology and nucleic acid techniques in environmental microbiology. Both applied methods (such as cultivation and preparation) and theoretical modeling (such as bioenergetic calculation programs and imaging) are discussed. A significant number of chapters on methods in activity measurement are included.

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Introduction To Immunotoxicology

Introduction To Immunotoxicology
by Jacques Descotes (Author)

Product Details:
* Paperback: 250 pages
* Publisher: CRC (December 9, 1998)
* Language: English
* ISBN-10: 0748403078

Book Description:
This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of Major Immunotoxicants. The Second Part Describes The Latest Methods Used to detect and evaluate, preclinically and clinically, the unexpected Immunotoxic Effects Of Xenobiotics. Trends In Implementing Strategies And recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro Methods, Biomarkers Of Immunotixicity And Risk Assessment.

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Clinical Mycology

Clinical Mycology
by William E. Dismukes (Editor), Peter G. Pappas (Editor), Jack D. Sobel (Editor)

Product Details:
* Hardcover: 560 pages
* Publisher: Oxford University Press, USA (September 10, 2003)
* Language: English
* ISBN-10: 0195148096

Book Description:
About 40 years ago, when I started seeing patients in my specialty of infectious diseases, systemic fungal infections were relatively uncommon. The literature consisted mostly of case reports and uncontrolled descriptive studies, and little time was given to discussing clinical mycology at national meetings. Times have changed. Clinical mycology could almost warrant a subspecialty designation because of the number of patients who are infected, the expansion of literature that deals with the basic mechanism of pathogenesis and virulence of fungal infections, and the number of controlled clinical studies on the topic. Forty years ago, the only drug that was available to treat systemic fungal infections was amphotericin B. In 2004, at least 10 antifungal agents are approved to treat systemic infections (not counting combinations), and more drugs are in the pipeline. (Figure) This relatively recent explosion of literature on mycology clearly needs to be brought together into one sourcebook. Dismukes, Pappas, and Sobel have succeeded in doing this in a splendid fashion. Dismukes and Pappas have been conducting clinical studies on antifungal agents for many years as participants in the Bacteriology and Mycology Study Group, sponsored by the National Institute of Allergy and Infectious Diseases. Dr. Sobel is a leading clinical investigator focusing on candida infections. The three editors have assembled an impressive list of contributors to put together a well-written, informative textbook about all of the important systemic and superficial fungal infections. This book is oriented toward the clinician. The general section on medical mycology is brief, as is the general section on epidemiology. That is probably as it should be in a book that is focused on clinical mycology. The chapter on laboratory aspects of medical mycology would have been helped by a table or a figure summarizing general taxonomy. The excellent section on systemic antifungal drugs is up to date and complete -- and the tables summarizing the options for treatment are particularly helpful. Many of the recommendations are repeated in the chapters on individual mycoses, but repetition is good when it emphasizes important points in diagnosis and therapy. Clinical studies and treatment guidelines for the individual groups of infections are summarized in easy-to-read tables. In every case, the recommendations are reasonable and consistent with the source literature, and the editing is excellent. The section that describes special populations of patients who are highly susceptible to systemic fungal infections emphasizes the book's clinical orientation and answers all the important questions about epidemiology, diagnosis, prophylaxis, and treatment. Minor points to mention are that the chapters dealing with medical mycology and epidemiology are the least useful ones and could be combined. The color photographs of patients with various fungal diseases are excellent but would be more helpful if they were incorporated into the relevant chapters. As I read the book, I wondered whether experts in the field could learn something from it. My answer is yes. Old material is reviewed, and the authors' conclusions and recommendations are reasonable. The book also presents material that was new to me, even in areas in which I have a special interest. This textbook will be very useful to any specialist in infectious diseases or to any physician who cares for immunodeficient patients. It will greatly add to the information covered by standard textbooks on medicine and infectious diseases and will answer many questions that are now the subject of Internet searches. I look forward to using it extensively in my practice. Gerald Medoff, M.D.
Copyright © 2004 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS.

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Micronutrients and HIV Infection

Micronutrients and HIV Infection
by Henrik Friis (Editor)

Product Details:
* Hardcover: 272 pages
* Publisher: CRC (September 14, 2001)
* Language: English
* ISBN-10: 0849300851

Book Description:
Micronutrients and HIV Infection provides a comprehensive overview of the topic through a review of recently published human studies and intervention trials and other important literature. It begins by providing the reader with basic background information and a conceptual framework for understanding the topic. Then the book covers micronutrients of particular interest and relevance to the topic. Finally, the book discusses how the previously introduced information can be applied for the benefit of people with HIV or countries where HIV is widespread and treatment unavailable.

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Molecular Mechanisms of Pathogenesis in Chagas' Disease

Molecular Mechanisms of Pathogenesis in Chagas' Disease (Medical Intelligence Unit)
by John M. Kelly (Editor)

Product Details:
* Hardcover: 172 pages
* Publisher: Springer; 1 edition (August 31, 2003)
* Language: English
* ISBN-10: 0306478498

Book Description
Chagas' disease, which results from infection with the single cell parasite Trypanosoma cruzi, is a debilitating condition that is a major problem in many parts of Latin America. Rapid technical progress is now facilitating dissection of the molecular mechanisms of disease pathogenesis, a process that will ultimately provide new strategies to alleviate the enormous public health burden associated with the infection. In this book, international experts review the buoyant status of Chagas' disease research as we enter the "post-genome" era and speculate on how the new findings will impact on drug and vaccine development. The chapters outline how progress is being made on several fronts ranging from parasite population genetics to human immunology. Researchers, physicians and students with an interest in any aspect of molecular parasitology should find this book to be a valuable reference

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PCR Sequencing Protocols

PCR Sequencing Protocols (Methods in Molecular Biology)
by Ralph Rapley (Editor)

Product Details:
* Spiral-bound: 221 pages
* Publisher: Humana Press; 1 edition (January 15, 1996)
* Language: English
* ISBN-10: 0896033449

Book Description
A superb, comprehensive collection of the most reliable protocols for PCR sequencing-all developed and described by eminent researchers and scientists who use them successfully every day. These protocols deal practically with those problems accompanying the rapid reassociation of amplified complementary strands by showing how sequencing reactions may be effectively modified, as well as complex methods of primer manipulation that enable the affinity purification, or its transcript production, of homogeneous single strands. They also provide all the necessary details of PCR purification, primer labeling, the preparation of sequencing gels, as well as of conventional methods for cloning PCR products into vectors and their subsequent sequencing.

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Dendritic Cell Protocols

Dendritic Cell Protocols (Methods in Molecular Medicine)
by Stephen P. Robinson (Editor), Andrew J. Stagg (Editor)

Product Details:
* Hardcover: 480 pages
* Publisher: Humana Press; 1 edition (August 2001)
* Language: English
* ISBN-10: 0896035840

Book Description
Stephen P Robinson, MD, PhD, and Andrew Stagg, PhD, have brought together a wide range of time-proven methods for studying these dendritic cells. Many of these readily reproducible techniques deal with the problem of obtaining sufficient dendritic cells for analysis, whether by isolation from a wide vareity of tissues, or from various progenitor cell populations. Other methods describe in step-by-step fashion the techniques commonly used for analyzing aspects of dendritic cells, ranging from cell migration to antigen uptake and T cell stimulation. In addition, a few techniques explore the practical challenges involved in using dendritic cells in a clinical setting to develop novel immunotherapeueutics.

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Immunology and Immunopathogenesis of Malaria

Immunology and Immunopathogenesis of Malaria (Current Topics in Microbiology and Immunology)
by Jean Langhorne (Editor)

Product Details:
* Hardcover: 234 pages
* Publisher: Springer; 1 edition (October 26, 2005)
* Language: English
* ISBN-10: 3540257187

Book Description
Malaria is still a major global health problem, killing more than 1 million people every year. Almost all of these deaths are caused by Plasmodium falciparum, one of the four species of malaria parasites infecting humans. This high burden of mortality falls heavily on Sub-Saharan Africa, where over 90% of these deaths are thought to occur, and 5% of children die before the age of 5 years. The death toll from malaria is still growing, with malaria-specific mortality in young African children estimated to have doubled during the last twenty years. This increase has been associated with drug resistance of the parasite, spread of insecticide resistant mosquitoes, poverty, social and political upheaval, and lack of effective vaccines. This collection of reviews addresses many of these important issues of malarial immunity and immunopathology. They are of interest not only to malariologists, but hopefully also to the broader immunological community. Strong interactions with, and feedback from immunologists working in other infectious diseases and in basic immunology will help us to move the field of malaria immunology and therapeutic intervention forward more quickly.

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The Biology and Pathology of Innate Immunity Mechanisms

The Biology and Pathology of Innate Immunity Mechanisms (ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Volume 479)
by Yona Keisari (Editor), Itzhak Ofek (Editor)

Product Details:
* Hardcover: 338 pages
* Publisher: Springer; 1 edition (June 1, 2000)
* Language: English
* ISBN-10: 0306464098

Book Description
This book is the proceedings of the Bathsheva de Rothschild Seminar on Innate Immunity, held on October 10-15, 1999, in Zichron Yaakov, Israel. In recent years, scientific attention has focused increasingly on immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body's defense. Identification of pathogens by these mechanisms primarily involves receptors recognizing sugar moieties of various microorganisms. This major new volume describes the recent discoveries in this field, including the implications of the recognition of specific components of the innate immunity arsenal as the main cause of host susceptibility to particular types of infections, and the development of new agents to combat infections using newly identified anti-microbial peptides. There is also coverage of the major themes, such as (i) the role of innate immune responses as a first-line defense against microbial infection and tumor cells; (ii) the cellular and molecular basis of the function of cells and molecules involved in innate immunity; (iii) the role of innate immunity in the immunocompromised host; and (iv) the interactions between innate immunity components and clonal immune response.

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Acute and Chronic Cough

Acute and Chronic Cough (Lung Biology in Health and Disease)
by Anthony E. Redington (Editor), Alyn H. Morice (Editor)

Product Details:
* Hardcover: 464 pages
* Publisher: Informa Healthcare (July 13, 2005)
* Language: English
* ISBN-10: 0824759583


Book Description:
A comprehensive review of the scientific and clinical aspects of acute and chronic cough, this reference focuses on recent developments in our understanding of the molecular biology of putative cough receptors, the neural mechanisms involved in the afferent and efferent limbs, the central processing of the cough reflex, and peptides and other substances that may mediate or modulate the cough reflex. With chapters wriitenby acknowledged authorities in the field, this handbook covers current and potential therapeutic agents, various methodologies to measure cough reflex sensitivity, and clinical approaches for the assessment of chronic cough in adults and children.

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In Silico Immunology

In Silico Immunology
by Darren Flower (Editor), Jon Timmis (Editor)

Product Details:
* Hardcover: 451 pages
* Publisher: Springer; 1 edition (December 1, 2006)
* Language: English
* ISBN-10: 0387392386

Book Description
Theoretical immunology is the application of mathematical modeling to diverse aspects of immunology. Immunoinformatics, the application of computational informatics to the study of immunological macromolecules, addresses questions in immunobiology and vaccinology, as well as addressing issues of data management, and can design and implement new experimental strategies. Artificial Immune Systems (AIS) uses ideas and concepts from immunology to guide and inspire new algorithms, data structures, and software development.
These three different disciplines are now poised to engineer a paradigm shift from hypothesis- to data-driven research, with new understanding emerging from the analysis of complex datasets: theoretical immunology, immunoinformatics, and Artificial Immune Systems (AIS). "in silico Immunology" will summarize these emergent disciplines and will address the issue of synergy as it shows how these three are set to transform immunological science and the future of health care.

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Meningococcal Vaccines: Methods and Protocols

Meningococcal Vaccines: Methods and Protocols (Methods in Molecular Medicine, 66) (Methods in Molecular Medicine)
by Andrew J. Pollard (Editor), Martin C.J. Maiden (Editor)

Product Details:
* Hardcover: 416 pages
* Publisher: Humana Press; 1 edition (June 2001)
* Language: English
* ISBN-10: 0896038017

Book Description
Andrew Pollard and Martin Maiden have assembled an impressive collection of the latest molecular and cellular techniques for the development, evaluation, and implementation of vaccines to be used against this dreaded disease. The contributors-leading scientists, clinicians, and public health physicians-describe in detail the many approaches to vaccine design, as well as the assessment of immune response to vaccine candidates and novel vaccine formulations. Timely and comprehensive, Meningococcal Vaccines: Methods and Protocols provides the scientist, public health physician, epidemiologist, clinical microbiologist, and clinician with the essential tools to lay bare the secrets of the meningococcus, and to develop, evaluate, and implement successful new meningococcal vaccines.

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Antibacterial Peptide Protocols

Antibacterial Peptide Protocols (Methods in Molecular Biology)
by William M. Shafer (Editor)

Product Details:
* Hardcover: 259 pages
* Publisher: Humana Press; 1 edition (August 15, 1997)
* Language: English
* ISBN-10: 0896034089

Book Description
Leading experts review for the first time in one volume all the mjaor biochemical, molecular, bacteriological, and physical techniques available to assess antimicrobial peptides. These state-of-the-art methods ensure easily reproducible results in such important procedures as the isolation and characterization of antimicrobial peptides, the molecular characterization of genes encoding antimicrobial peptides, and the use of expression systems to isolate peptides. Bioassays and microbial genetic techniques are also included, as are antibacterial assays as the final readout system.

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Regulatory T Cells in Inflammation

Regulatory T Cells in Inflammation (Progress in Inflammation Research)
by Leonie S. Taams (Editor), Arne N. Akbar (Editor), Marca H.M. Wauben (Editor)

Product Details:
* Hardcover: 240 pages
* Publisher: Birkhäuser Basel; 1 edition (May 31, 2005)
* Language: English
* ISBN-10: 3764370882

Book Description
Scientific interest in regulatory T cells has revived during the last decade. Initially described in the early seventies as suppressor T cells, the concept of suppressor/regulatory T cells went through turbulent times during the eighties when molecular analysis failed to identify putative suppressor genes. The constructive and elegant cellular experiments on regulatory T cells during the nineties, initiated by Shimon Sakaguchi and co-workers, however have brought these cells back into the limelight. Nowadays, regulatory T cells are regarded as essential components of the immune system, and several different subsets of regulatory T cells have been described. Considerable regulatory function has been attributed to the CD4+CD25+ T cell subset. These cells act by suppressing adaptive and possibly also innate immune responses thereby maintaining or restoring the balance between immunity and tolerance. The suppressive effects of CD4+CD25+ regulatory T cells are cell-contact dependent but a role for soluble factors, particularly in vivo, has been suggested as well.
The aim of this book is to bring together recent developments and viewpoints in the field of CD4+CD25+ regulatory T cells and to discuss the potential use of regulatory T cells in immunotherapy of inflammatory diseases. By linking data on regulatory T cells from experimental models with recent findings from the clinic, this topical book will be of interest to immunologists and other biomedical researchers as well as clinicians that are interested in regulation and manipulation of the immune response during (chronic) inflammatory disease.

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Malaria Methods and Protocols

Malaria Methods and Protocols (Methods in Molecular Medicine)
by Denise L. Doolan (Editor)

Product Details:
* Hardcover: 648 pages
* Publisher: Humana Press; 1 edition (July 2002)
* Language: English
* ISBN-10: 0896038238

Book Description
Internationally respected scientists and clinicians describe in step-by-step detail their most useful conventional and cutting-edge techniques for the study of malaria. Areas covered include clinical and laboratory diagnosis and typing, animal models, molecular biology, immunology, cell biology, vaccinology, laboratory models, and field applications. Each readily reproducible protocol has been tested, standardized, and optimized for experimental success, and includes many laboratory notes on troubleshooting, avoiding pitfalls, and interpreting results. Several of the most widely used methods are described here in detail for the first time or have been thoroughly updated since their original publication (e.g., in vitro culture of Plasmodium parasites and in vitro growth inhibition assay).

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Cystic Fibrosis: Methods and Protocols

Cystic Fibrosis: Methods and Protocols (Methods in Molecular Medicine)
by William R. Skach (Editor)

Product Details:
* Hardcover: 608 pages
* Publisher: Humana Press; 1 edition (March 2002)
* Language: English
* ISBN-10: 0896038971

Book Description
Cystic Fibrosis: Methods and Protocols consolidates cutting-edge in vitro, cellular, and whole animal laboratory protocols into an indispensable resource. From electrophysiology and cell biology, to animal models and gene therapy, this comprehensive set of methods provides the step-by-step instructions needed for investigators to incorporate new approaches into their research programs. Specific protocols describe new techniques for diagnosis, in vitro methods for the expression and functional analysis of CFTR, novel biochemical and cellular systems to determine how mutations subvert CFTR function, and in vivo protocols to examine how CFTR dysfunction produce multisystem pathology in both human and animal models.

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Atomic Force Microscopy: Biomedical Methods and Applications

Atomic Force Microscopy: Biomedical Methods and Applications (Methods in Molecular Biology)
by Pier Carlo Braga (Editor), Davide Ricci (Editor)

Product Details:
* Hardcover: 408 pages
* Publisher: Humana Press; 1 edition (October 2, 2003)
* Language: English
* ISBN-10: 1588290948

Book Description
Highly experienced physicians and biologists clearly explain the basic technical knowledge needed to use AFM and demonstrate its multifarious uses in biomedicine and the life sciences. The applications range widely from morphostructural analyses of cellular structures, to the investigation of subcellular structures, to functional investigations, and reveal a powerful new way of looking at biological samples. The methods clearly demonstrate the advantages of AFM over traditional life science microscopy, among them simultaneous very high magnification and resolution, minimal tissue and cell preparation, and the ability to obtain different views of the sample from a single data collection.

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Confocal Microscopy Methods and Protocols

Confocal Microscopy Methods and Protocols (Methods in Molecular Biology)
by Stephen W. Paddock (Editor)

Product Details:
* Paperback: 446 pages
* Publisher: Humana Press; 1 edition (January 15, 1999)
* Language: English
* ISBN-10: 0896035263


Book Description
Stephen Paddock and a highly skilled panel of experts lead the researcher using confocal techniques from the bench top, through the imaging process, to the journal page. They concisely describe all the key stages of confocal imaging-from tissue sampling methods, through the staining process, to the manipulation, presentation, and publication of the realized image. Written in a user-friendly, nontechnical style, the methods specifically cover most of the commonly used model organisms: worms, sea urchins, flies, plants, yeast, frogs, and zebrafish. The powerful hands-on methods collected here will help even the novice to produce first-class cover-quality confocal images.

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Nonviral Vectors for Gene Therapy

Nonviral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
by Mark A. Findeis (Editor)

Product Details:
* Hardcover: 416 pages
* Publisher: Humana Press; 1 edition (August 9, 2001)
* Language: English
* ISBN-10: 0896037126

Book Description
Mark A. Findeis and a panel of active researchers present their best methods not only for preparing, handling, and characterizing gene delivery agents, but also for gene delivery. To help those preparing and characterizing gene transfer agents, the contributors examine a broad range of compounds that bind with DNA to form the compact condensed phases that facilitate cellular delivery-among them peptide conjugates, synthetic polymers, and lipids. They also outline specific approaches to gene transfer in vivo, including direct delivery by intratumoral injection and indirect delivery by cell-specific targeting of DNA complexes, and discuss in detail many spectroscopic techniques for characterizing nonviral gene delivery agents.

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Human Polyomaviruses: Molecular and Clinical Perspectives

Human Polyomaviruses: Molecular and Clinical Perspectives
by Kamel Khalili (Author), Gerald L. Stoner (Author)

Product Details:
* Hardcover: 704 pages
* Publisher: Wiley-Liss; 1st edition (January 15, 2002)
* Language: English
* ISBN-10: 0471390097

Book Description:
"This multi-authored book provides a fascinating account of the discovery of JC virus, BK virus and the related Simian polyomavirus SV40, as well as their associated diseases, spanning the past 50 years...Moreover, this unique book really provides a roadmap for future research...It will certainly appeal to all medical and graduate students, to infectious diseases specialists, and those involved in the field of DNA virus research."

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Gene Transfer and Expression Protocols

Gene Transfer and Expression Protocols (Methods in Molecular Biology)
by Edward J. Murray (Author)

Product Details:
* Hardcover: 456 pages
* Publisher: Humana Press; 1 edition (April 22, 1991)
* Language: English
* ISBN-10: 0896031780

Book Description
Murray's new handbook on Gene Transfer and Expression Protocols sets forth both current and new methodologies in a clear, concise, easy-to-follow manner, following the successful formula of the classic volumes in Humana's Methods in Molecular Biology series. Each chapter is devoted to a thorough exposition of a single technique. An Introduction explains the significance of the protocol and provides background information. A Materials section lists all the requirements for the technique discussed. A Methods section details the procedure in a step-by-step protocol. A Notes section alerts the reader to pitfalls that may be encountered, as well as alternatives that may be used for successful completion of the experiment. Each technique is designed to guarantee optimum results.
This volume is an outstanding new benchtop manual that provides protocols for introducing an isolated gene into a cell line, using various transfection techniques. Topics and techniques include:
viral vectors • reporter genes • analysis of steady-state level of transcription • assay for newly initiated transcriptional complexes • immunocytological techniques • assay of structure and replication state of transfected genes • overall strategy for defining regulatory sequences
Providing the latest techniques in a fast-paced area, Gene Transfer and Expression Protocols is an absolutely essential handbook for everyone involved in cytogenetics, cell genetics, molecular biology, and related fields.

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Antiviral Methods and Protocols

Antiviral Methods and Protocols (Methods in Molecular Medicine)
by Derek Kinchington (Editor), Raymond F. Schinazi (Editor)

Product Details:
* Hardcover: 420 pages
* Publisher: Humana Press; 1 edition (September 25, 1999)
* Language: English
* ISBN-10: 0896035611

Book Description
Experienced scientists describe-in an easily-followed format-their state-of-the-art techniques for evaluating antiviral compounds. The assays described include systems for investigating drugs used against herpesviruses, hepatitis viruses, human immunodeficiency viruses, human papillomaviruses, and influenza viruses. These well-tested methods range from cellular assays to some of the most up-to-date molecular approaches for identifying compounds that are active against viral enzymes and the development of viral resistance against drugs currently in use. Timely and comprehensive, Antiviral Methods and Protocols offers today's researchers in academia, clinical departments, and the pharmaceutical industry the powerful, reproducible, and novel methods needed to evaluate compounds effective against both acute and chronic infections.

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Immunology of Fungal Infections

Immunology of Fungal Infections
by Gordon D. Brown (Editor), Mihai G. Netea (Editor)

Product Details:
* Hardcover: 500 pages
* Publisher: Springer; 1 edition (January 2007)
* Language: English
* ISBN-10: 1402054912

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Cell Death During HIV Infection

Cell Death During HIV Infection
by Andrew D. Badley (Editor)

Product Details:
* Hardcover: 560 pages
* Publisher: CRC (November 29, 2005)
* Language: English
* ISBN-10: 0849328276

Book Description:
Until now, researchers lacked a complete resource on the cell death observed during HIV infection. Cell Death During HIV Infection contains comprehensive, current information for researchers and clinicians, combining elements of HIV biology with immunology and focusing on their interaction. The discussion centers on mechanisms by which HIV may accelerate T cell death, on correlations between apoptosis and HIV disease using animal models and clinical studies, and the involvement of apoptosis in the complications of HIV. A final section deals with the impact of therapies on HIV-associated T cell death and avenues by which modulation of apoptosis can be developed into novel therapeutic strategies for HIV disease.

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Fasciolosis

Fasciolosis
by J. P. Dalton (Editor)

Product Details:
* Hardcover: 562 pages
* Publisher: CABI Publishing (May 24, 1999)
* Language: English
* ISBN-10: 0851992609

Book Description
Fasciolosis, a parasitic disease caused by the liver fluke, has a tremendous impact on livestock each year. In addition, an estimated 2.4 million people are infected, and the disease is now recognized as an emerging human disease by the World Health Organization. This volume, the first comprehensive treatment devoted to these parasites and their control in over thirty years, brings together the many recent scientific advances and treatments, making it invaluable resource for doctors, parasitologists, and veterinarians.

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The Sepsis Text

The Sepsis Text
by Jean-Louis Vincent (Editor), Jean Carlet (Editor), Steven M. Opal (Editor)

Product Details:
* Hardcover: 872 pages
* Publisher: Springer; 1 edition (February 2002)
* Language: English
* ISBN-10: 079237620X

Book Description:
Sepsis, defined in its broadest sense as the syndrome evoked by the host response to infection, remains one of the most challenging problems in intensive care medicine. According to the Centers for Disease Control and Prevention (CDC), 500,000 cases of sepsis occur annually in the United States, an increase of almost 140 percent over the past decade. Up to 14 percent of all patients admitted to intensive care units are affected by sepsis. When sepsis becomes severe and progresses to septic shock, multiple-organ dysfunction aggravates and prolongs the critical illness, necessitating a lengthy intensive care stay, and dramatically increases the risk of death. Although our understanding of the mechanisms underlying the evolution from infection to sepsis and multiple-organ failure has evolved substantially, mortality rates remain as high as 50 percent, depending on the definition of sepsis that is used. With the associated morbidity, the economic burden of sepsis also remains high. Novel therapies have been introduced, but many of the "magic bullets" have failed to improve the outcome. Today, after seemingly endless frustration, there finally appears to be some light at the end of the tunnel, and this book is therefore timely. The goal of the editors of the The Sepsis Text was to provide a comprehensive review of recent achievements in the management of sepsis, based on basic and applied research performed in recent years by innovative scientists and clinical investigators worldwide. Many of the 94 contributing authors, most of whom are American or European, spearheaded this research, and together with the editors, they have attempted to integrate the knowledge that they believe will soon lead to the development of effective therapies for sepsis. The book has seven sections, each of which comprises a number of brief chapters in the form of essays by experts in the field. This approach, as opposed to the classic textbook approach, inevitably results in some redundancy and overlap. In general, the chapters are well organized and thoroughly referenced, but unfortunately, the book was published just before the appearance of a few breakthrough articles. There is a paucity of tables and diagrams, and the few photographic illustrations are black and white, which makes them obscure and uninformative. Some of the more basically oriented chapters are truly outstanding and of major importance for those involved in research on sepsis. The clinical parts of the text, wherever applicable, provide published recommendations from recent consensus conferences -- useful guidelines for fellows and senior clinicians seeking to apply evidence-based medicine. Most topics are discussed in detail, and every chapter concludes with a brief, useful summary. The introductory section is on "generalities": the continuing controversy about how to define sepsis accurately, the increased incidence of sepsis and its impact on health care, diagnostic criteria, genetic predisposition, and quantification of risk. Although informative, these chapters often do not provide the depth that is achieved in later parts of the book. The section on pathophysiology is truly outstanding. I especially liked the chapter on the immunopathogenesis of gram-negative shock, with its extensive discussion of the Toll receptors, and the chapters on proinflammatory and antiinflammatory cytokines and the pathophysiology of immune depression in the critically ill. The emerging idea that cytopathic hypoxia, rather than microcirculatory failure, causes organ dysfunction in sepsis is illuminating, and its implications are discussed in depth. Unfortunately, however, this chapter was written before the publication of a report that accurately describes the mitochondrial defects in relation to sepsis-induced organ failure. The next two sections focus on clinical aspects of sepsis, critically evaluating progress and controversies with regard to monitoring systems and general support. There is new compelling evidence in favor of early goal-directed hemodynamic optimization in patients with sepsis, guided by invasive monitoring. Again, it is a pity that the book was published before these findings could be incorporated into the recommendations. The chapter on the management of respiratory disorders in patients with sepsis -- the acute respiratory distress syndrome being the most important -- does not address the results of a study showing that the prone position, which is recommended in the chapter, in fact does not improve the outcome of the acute respiratory distress syndrome. The section on specific microbiologic issues -- in particular, the chapters on catheter-related infections and on isolation procedures in the intensive care unit -- is informative and contains updated CDC guidelines for clinical practice. The section on complications of sepsis comprises several chapters dealing with organs and systems as distinct entities, an approach that is somewhat artificial and prone to overlap with previous sections. The excellent chapter on coagulation is a notable exception; it is loaded with fascinating new information, and in view of the importance of these new insights, it would have benefited from a more detailed discussion of the interaction between coagulation and inflammation in the pathophysiology of sepsis. The final section elegantly summarizes the complete set of clinical studies that have evaluated approaches to the treatment of sepsis, as well as the preclinical data on which they were based, from anticytokine therapies, corticosteroid therapy, immunonutrition, and hemofiltration to interference with the coagulation system and the development of vaccines against bacterial endotoxins. Although the results of many trials have been disappointing, some promising findings have emerged. The editors and contributing authors should be congratulated for their excellent reviews of recent progress in our understanding of sepsis and in its management. The Sepsis Text clearly conveys their enthusiasm and provides encouragement to all those working in the field.

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Septic Shock: Methods and Protocols

Septic Shock: Methods and Protocols (Methods in Molecular Medicine)
by Thomas J. Evans (Editor)

Product Details:
* Hardcover: 205 pages
* Publisher: Humana Press; 1 edition (January 15, 2000)
* Language: English
* ISBN-10: 0896037304

Book Description
An interdisciplinary panel of expert investigators describe proven methods for investigating the often deadly mechanisms of septic shock. Drawing on insights from a wide variety of fields-ranging from molecular and cellular biology to the physiological measurement of entire animals-these experienced research workers detail the most important techniques for studying sepsis involving endotoxins, toxins derived from Gram-positive organisms, cytokines, nitric oxide and other reactive nitrogen intermediates, and primary cell cultures. They also treat a number of significant techniques that are not well described in the literature, including the the Limulus endotoxin assay, the bioassay of TNF, the purification of bacterial endotoxin and superantigens, and the culture of primary human cells. Multidisciplinary and state-of-the-art, Septic Shock Methods and Protocols offers both experimental and clinical investigators a gold-standard collection of key methods for illuminating the basic pathophysiological processes that occur following infection.

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Adenoviruses: Basic Biology to Gene Therapy

Adenoviruses: Basic Biology to Gene Therapy (Medical Intelligence Unit 15)
by Prem Seth (Editor)

Product Details:
* Hardcover: 314 pages
* Publisher: Landes Bioscience (September 15, 1999)
* Language: English
* ISBN-10: 1570595844

Book Description:
Ever since their discovery, adenoviruses have proven to be tremendous asset to biologists. Through the study of the adenoviruses the authors have learned not only about the virus structures, mechanisms of viral replication, but also about eukaryotic gene expression, alternative splicing, regulation of cell cycle progression, and apoptosis. In the last five years, there has been an explosion in the use of adenoviruses as vectors for gene transfer to a variety of mammalian cells. Adenoviral vectors are also being tested in Phase I clinical trials for cystic fibrosis and for many kinds of cancers. These recent developments in utilizing adenoviral vectors for gene therapy have rejuvenate an interest in the basic science of adenovirus research. More importantly, it has generated a necessity for a single volume that covers both the biology of adenoviruses as well as our progress in the use of adenoviruses as vectors for gene therapy. This book was written precisely to fulfill such a need.

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Advances in Parasitology, Volume 55

Advances in Parasitology, Volume 55 (Advances in Parasitology)
by John R. Baker (Series Editor), Ralph Muller (Series Editor), David Rollinson (Series Editor)

Product Details:
* Hardcover: 232 pages
* Publisher: Academic Press (December 22, 2003)
* Language: English
* ISBN-10: 0120317559

Book Description:
Praise for the Series
"One is struck by the quality and scholarship of the various chapters and the obviously efficient editing."
--PARASITOLOGY
"The policy of the editors of Advances in Parasitology to include reviews from any aspect of parasitology and the high standard of individual papers have resulted in this series of volumes becoming an indispensable source for students, teachers, and research workers."
--ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

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AIDS, Rhetoric, and Medical Knowledge

AIDS, Rhetoric, and Medical Knowledge
by Alex Preda (Author)

Product Details:
* Hardcover: 288 pages
* Publisher: Cambridge University Press (November 29, 2004)
* Language: English
* ISBN-10: 0521837707

Book Description
Examining the formation of scientific knowledge about the AIDS epidemic in the 1980s, Alex Preda highlights the metaphors, narratives, and classifications which framed scientific hypotheses about the nature of the infectious agent and its transmission. Preda compares these arguments with those used in the scientific analysis of SARS. He demonstrates how scientific knowledge about epidemics is shaped by cultural narratives and categories of social thought through a detailed review of biomedical publications.

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Adenovirus Methods and Protocols

Adenovirus Methods and Protocols (Methods in Molecular Medicine)
by William S. M. Wold (Editor)

Product Details:
* Hardcover: 352 pages
* Publisher: Humana Press; 1 edition (January 15, 1999)
* Language: English
* ISBN-10: 0896035514

Book Description
A cutting-edge collection of readily reproducible methods for conducting research with adenoviruses, the premier and most widely used model in cell and molecular biology. The methods range from how to grow and titer adenoviruses and how to construct specific alterations in the adenovirus genome, to how to measure apoptosis induced by cells of the immune system, cytokines, and intrinsic apoptosis effectors. In addition, there are methods to study transcription and splicing with in vitro systems and for the adenovirus-mediated transformation of cells to a malignant state. Each method is written by a prominent investigator well-versed in the technique and includes a brief background discussion and tried, as well as true step-by-step instructions.

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Cytotoxic Drug Resistance Mechanisms

Cytotoxic Drug Resistance Mechanisms (Methods in Molecular Medicine)
by Robert Brown (Editor), Uta Böger-Brown (Editor)

Product Details:
* Hardcover: 238 pages
* Publisher: Humana Press; 1st edition (April 15, 1999)
* Language: English
* ISBN-10: 0896036030

Book Description
Leading clinical and laboratory scientists describe cutting-edge methods for examining the mechanisms of cellular resistance to anticancer cytotoxics in human tumors. The protocols contain detailed instructions and extensive troubleshooting tips that allow researchers effectively to study a wide variety of drug resistance mechanisms, including aspects of drug-induced cell death, drug uptake/efflux, drug metabolism, and DNA repair. Each method is designed to help identify the correlation between molecular and biochemical data and the clinical responses of the patient. Cytotoxic Drug Resistance Mechanisms illuminates all the clinically relevant mechanisms used as markers of the biological response to anticancer biotherapeutics today.

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The Neutrophil: An Emerging Regulator of Inflammatory and Immune Response

The Neutrophil: An Emerging Regulator of Inflammatory and Immune Response (Chemical Immunology)
by Marco A. Cassatella (Editor)

Product Details:
* Hardcover: 232 pages
* Publisher: Not Avail (May 2003)
* Language: English
* ISBN-10: 3805575521

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Cytokines and Colony Stimulating Factors

Cytokines and Colony Stimulating Factors: Methods and Protocols (Methods in Molecular Biology)
by Dieter Körholz (Editor), Wieland Kiess (Editor)

Product Details:
* Hardcover: 496 pages
* Publisher: Humana Press; 1 edition (November 8, 2002)
* Language: English
* ISBN-10: 1588290352

Book Description
Hands-on laboratory experts describe for the novice investigator a host of novel technologies and molecular techniques specifically designed to study cellular immunology and promote its gene therapy applications. Presented in step-by-step detail to ensure ready reproducibility, these protocols range from flow cytometric techniques to detect cytokines and growth factors in different specimens, to methods for generating and expanding dendritic cells and hematopoietic progenitors from different origins. Although the protocols require little previous experience, even highly skilled researchers will augment their skills with many novel timesaving techniques.

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Hepatitis B and D Protocols: Volume 1: Detection, Genotypes, and Characterization

Hepatitis B and D Protocols: Volume 1: Detection, Genotypes, and Characterization (Methods in Molecular Medicine)
by Robert K. Hamatake (Editor), Johnson Y. N. Lau (Editor)

Product Details;
* Hardcover: 376 pages
* Publisher: Humana Press; 1 edition (January 28, 2004)
* Language: English
* ISBN-10: 1588291057

Book Description
A broad-ranging collection of core techniques for the study of HBV and HDV infections and for the development of therapies to treat them. In this first of two volumes Detection, Genotypes, and Characterization, the authors focus on readily reproducible molecular methods for the identification and quantification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle underlying the technique, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. An accompanying second volume, Immunology, Model Systems, and Clinical Studies, contains user-friendly protocols for the study of host immune responses to infection, in vitro and in vivo models of infection, and the development of antivirals.

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Hepatitis B and D Protocols: Volume 2: Immunology, Model Systems, and Clinical Studies

Hepatitis B and D Protocols: Volume 2: Immunology, Model Systems, and Clinical Studies (Methods in Molecular Medicine)
by Robert K. Hamatake (Editor), Johnson Y. N. Lau (Editor)

Product Details:
* Hardcover: 600 pages
* Publisher: Humana Press; 1 edition (January 28, 2004)
* Language: English
* ISBN-10: 1588291081

Book Description
A broad-ranging collection of cutting-edge techniques for the study of HBV and HDV infections and for the development of therapies to treat them. In this second of two volumes, Immunology, Model Systems, and Clinical Studies, the authors focus on protocols for the study of host immune responses to infection, in vitro and in vivo models of infection, and the development of antivirals. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle underlying the technique, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. An accompanying first volume, Detection, Genotypes, and Characterization, contains user-friendly protocols for the identification and quantification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle.

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Hepatitis C Protocols

Hepatitis C Protocols (Methods in Molecular Medicine)
by Johnson Y. N. Lau (Editor)

Product Details:
* Hardcover: 648 pages
* Publisher: Humana Press; 1 edition (September 18, 1998)
* Language: English
* ISBN-10: 0896035212

Book Description:
Johnson Lau and his expert collaborators present cutting-edge techniques for study of the hepatitis C virus, a disease afflicting over 100 million people worldwide. The methods range from the detection of anti-HCV in serum and HCV in liver tissue to HCV genotypes and the detection and quantification of HCV in serum. In addition to these key protocols, the authoritative contributors also evaluate recombinant proteins in immunological test systems, including the identification of important antigenic epitopes, antibodies, and recombinant antigens. The methods and systems detailed in this book will play a key role in the development of more effective antivirals, in the introduction of vaccines, and in a deeper understanding of viral replication strategies, viron structure, and the mechanisms of viron assembly and release.

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Bergey's Manual® of Systematic Bacteriology: Volume Two: The Proteobacteria

Bergey's Manual® of Systematic Bacteriology: Volume Two: The Proteobacteria (Part C) (Bergey's Manual of Systematic Bacteriology (Springer-Verlag))
by George Garrity (Editor), Don J. Brenner (Editor), Noel R. Krieg (Editor), James T. Staley (Editor), David R. Boone (Editor), Paul De Vos (Editor), Michael Goodfellow (Editor), Fred A. Rainey (Editor), George M. Garrity (Editor), Karl-Heinz Schleifer (Editor)

Product Details:
* Hardcover: 1388 pages
* Publisher: Springer; 2 edition (August 25, 2005)
* Language: English
* ISBN-10: 0387241450

Book Description

Since publication of the first edition of Bergey’s Manual of Systematic Bacteriology, it has become recognized throughout the world as the principal monographic work in the field of prokaryotic biology. Like a dictionary to a writer, the Manual is usually the first reference that a microbiologist consults when questions arise regarding the characteristics of an unfamiliar species or an unknown strain that bears some similarity to a more familiar one. While the first edition has served the community well for many years, it has become outdated. As a result, the editorial board of Bergey’s Manual Trust, in collaboration with more than 500 of the world’s leading authorities in prokaryotic systematics, is in the process of revising Bergey’s Manual of Systematic Bacteriology so that it reflects current thinking and advances in the field.
Background
Rapid advances in DNA sequencing technology have led to a major change in the way that prokaryotes are classified. Sequence analysis of highly conserved regions of the bacterial genome, such as the small subunit rRNA gene, now provide us with a universal method of estimating the evolutionary relationships among all organisms. Such gene-based phylogenetic classifications have led to many new discoveries about prokaryotes that were not reflected in the classification used in the first edition of the Manual. We now know that the prokaryotes fall into two broad domains: the Archaea and the Bacteria. Whereas the Archaea were once thought of as the more primitive of the prokaryotic lineages, we now realize that they are more closely related to the eukaryotes than to the Bacteria by this measure. We have come to realize that many taxa based on shared phenotypic features may be quite distinct from one another based on phylogenetic evidence. The Chromatium, a genus of anoxygenic photosynthetic bacteria are more closely related to E. coli than to some other lineages of anoxygenic photosynthetic bacteria; Mycoplasma and other cell-wall deficient species are members of the Gram-positive clade; the medically important Chlamydia are aligned with the Planctomyces; and the Clostridium, which form a phenotypically coherent group, fall into more than a dozen phylogenetically disparate groups of Gram-positive bacteria. We have also come to realize that prokaryotes represent one of the major sources of biodiversity in nature and play a major role in the functioning of all ecosystems.
In addition to such fundamental revelations, the widespread application of new methods of classifying prokaryotes has led to an explosive growth in the number of validly published species and higher taxa. Since completion of the first edition of the Manual, the number of published species has more than tripled and has been accompanied by numerous taxonomic realignments that take into consideration newly published findings.
Phylogenetic classification is now broadly accepted as the preferred method of representing taxonomic relationships among prokaryotes and eukaryotes alike. While the evolutionary history of the prokaryotes is far from complete, there is already sufficient data to provide a reasonable view of the major lines of descent of the cultivable species. Although the second edition of the Manual retains it’s unique and highly structured style of presentation of information along genus and species lines, the arrangement of content is along the phylogenetic lines of the small subunit rRNA gene, so that the reader is presented with the information in a more natural, biological perspective. The second edition of the Manual also contains more in-depth ecological information about individual taxa and many new introductory essays.
In the preface to the first edition of Bergey’s Manual of Determinative Bacteriology, published in 1923, one of the stated goals of that work was to "stimulate efforts to perfect the classification of bacteria…" The editors of the first edition regarded the Manual as "a progress report leading to a more satisfactory classification in the future" rather than a definitive classification. Bergey’s Manual Trust continues in this tradition and recognizes that, for the Manual to remain scientifically meaningful and useful to the scientific community, it is time for the new edition.
Overview of the second edition of the Manual
As before, the Manual is subdivided into multiple volumes and each genus occurs as a separate chapter with introductory text provided at higher taxonomic levels. The second edition differs from the first in that clinically relevant species are not grouped together into two volumes. Rather, these taxa appear in their proper phylogenetic place. The text is arranged to follow the lineages defined by the large-scale phylogenetic trees maintained by the Ribosomal Database Project and the ARB Project to which a formalized, hierarchical taxonomy and nomenclature have been applied. As volume 2 goes to press, the taxonomy encompasses 6466 species that are assigned to 26 phyla, 41 classes, 88 orders, 240 families and 1194 genera. Each volume contains a collection of introductory essays on the history and use of the Manual; a detailed discussion of the prokaryotic domains; overviews of the classification, identification, and naming of prokaryotes; prokaryotic ecology and phylogeny; the role of culture collections in microbiology; and intellectual property of prokaryotes. Each volume also includes taxon specific essays and a detailed road map that presents the reader with a broad view of how the entire edition will be arranged, a mapping of phylogenetic groups to the phenotypic groups used in the first edition (Volume 1), or an update of newly published taxa and combinations appearing in print since the preceding volume (Volumes 2-5). The details of each volume in print (Volume 1), in press (Volume 2) or in preparation (Volumes 3-5) follow.
Volume 1 "The Archaea and the Deeply Branching and Phototrophic Bacteria" (2001) David R. Boone and Richard W. Castenholz (Volume Editors), George M. Garrity (Editor-in-Chief) with contributions from 105 colleagues. 742 pages with 320 figures and 95 tables. The volume provides descriptions of 413 species in 165 genera that are assigned to the phyla Crenarchaeota, Euryarchaeota, Aquificae, Thermatogae, Thermodesulfobacteria, "Deinococcus-Thermus", Chrysiogenetes, Chloroflexi, Thermomicrobia, Nitrospira, Deferribacteres, Cyanobacteria, and Chlorobi. In addition, the volume contains an introductory chapter to nonoxygenic, phototropic species of Bacteria belonging to the Proteobacteria and Firmicutes, which will be repeated in more detail in subsequent volumes.
Volume 2 "The Proteobacteria." (2004) Don J. Brenner, Noel R. Krieg, James T. Staley (Volume Editors), and George M. Garrity (Editor-in-Chief) with contributions from 339 colleagues. The volume provides descriptions of more than 2000 species in 538 genera that are assigned to the phylum Proteobacteria. This volume is subdivided into three parts. Part A, The Introductory Essays (332 pgs, 76 figures, 37 tables); Part B, The Gammaproteobacteria (1203 pages, 222 figures, and 300 tables); and Part C The Alpha-, Beta-, Delta-, and Epsilonproteobacteria (1256 pages, 512 figures, and 371 tables).
Volume 3 "The Firmicutes". (2005 anticipated). Paul De Vos, Dorothy Jones, Fred A. Rainey, Karl-Heinz Schleifer, Joseph Tully, (Volume Editors) and George M. Garrity (Editor-in-Chief), with contributions from 120 colleagues. This volume will provide descriptions of more than 1346 species in 235 genera belonging to the phylum Firmicutes. Anticipated length 2100 pages.
Volume 4 "The Actinobacteria". (2006 anticipated) 1141 species in 106 genera. Estimated page length: 878 with 192 tables and 321 figures. Michael Goodfellow, Peter Kaempfer, Peter H.A. Sneath, Stanley T. Williams (Volume Editors) and George M. Garrity (Editor-in-Chief) with contributions from 60 colleagues. This volume will provide descriptions of over 1534 species in 174 genera belonging to the phylum Firmicutes. Anticipated length 2454 pages.
Volume 5 "The Planctomycetes, Chlamydiae, Spirochetes, Fibrobacters, Bacteroidetes, Fusobacteria, Acidobacteria, Verrucomicrobia, Dictyoglomi, and Gemmatomonadetes " more than 405 species assigned to 114 genera in 10 phyla. Anticipated length: 648 pages Editors and authors under discussion.

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Bergey's Manual® of Systematic Bacteriology: Volume Two: The Proteobacteria, Part A Introductory Essays

Bergey's Manual® of Systematic Bacteriology: Volume Two: The Proteobacteria, Part A Introductory Essays (Bergey's Manual of Systematic Bacteriology (Springer-Verlag))
by George Garrity (Editor)

Product Details
* Hardcover: 304 pages
* Publisher: Springer; 2 edition (July 26, 2005)
* Language: English
* ISBN-10: 0387241434

Book Description
Since publication of the first edition of Bergey’s Manual of Systematic Bacteriology, it has become recognized throughout the world as the principal monographic work in the field of prokaryotic biology. Like a dictionary to a writer, the Manual is usually the first reference that a microbiologist consults when questions arise regarding the characteristics of an unfamiliar species or an unknown strain that bears some similarity to a more familiar one. While the first edition has served the community well for many years, it has become outdated. As a result, the editorial board of Bergey’s Manual Trust, in collaboration with more than 500 of the world’s leading authorities in prokaryotic systematics, is in the process of revising Bergey’s Manual of Systematic Bacteriology so that it reflects current thinking and advances in the field.

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Parasites of the Colder Climates

Parasites of the Colder Climates
by Hannah Akuffo (Editor), Inger Ljungstrm (Editor), Ewert Linder (Editor), Mats Wahlgren (Editor)

Product Details:
* Hardcover: 384 pages
* Publisher: CRC (December 5, 2002)
* Language: English
* ISBN-10: 0415275849

Book Description:
Many texts on parasitology concentrate on tropical parasitic infections, so the reader may think that parasites are not a problem in the north. Parasites of the Colder Climates redresses the balance by focusing on parasites indigenous to cooler climates. A multi-authored text, it provides a comprehensive overview of parasites in these areas and the diseases they cause. Topics include epidemiology, biology and pathogenesis, clinical presentations, laboratory analysis and methods for diagnosis. This text presents diagnostic methods and preventative information for epidemiologists, clinicians and parasitologists and is suitable for researchers, advanced undergraduates and postgraduates.

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The Science of HIV

The Science of HIV
by Michael Dispezio (Author)

Product Details:
* Paperback: 184 pages
* Publisher: National Science Teachers Association; (January 1997)
* Language: English
* ISBN-10: 0873551605

Book Description:
Combine biology and AIDS awareness in your classroom. The Science of HIV focuses on biological concepts relating to HIV, including cell biology, basic virology, immune system function, and genetics. The award-winning video contains animations, interviews with leading scientists and healthcare workers, and compelling stories of adolescents living with HIV.


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Biosafety In Microbiology And Biomedical Laboratory

Biosafety in Microbiological and Biomedical Laboratories
by Jonathan Y. Richmond (Editor), Robert W. McKinney (Editor)

Product Details:
* Plastic Comb: 250 pages
* Publisher: Not Avail; 4th edition (January 1999)
* Language: English
* ISBN-10: 0788185136

Book description:
The 4th edition of the BMBL has added sections on Risk Assessment, Security, Work with Prions. Additionally many of the agent summary statements have been modified and updated. This resource is a must for safety professionals that serve institutions that conduct biomedical and microbiological research. I always keep about 50 copies around just to give out to researchers.

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Encyclopedic Reference of Parasitology (Online)

Encyclopedic Reference of Parasitology: Biology, Structure, Function / Diseases, Treatment, Therapy
By: Heinz Mehlhorn(Editor)

Product Details:
* Hardcover: 1332 pages
* Publisher: Springer; 2 edition (June 27, 2001)
* Language: English
* ISBN-10: 3540662391

Book Description:
Recent advances in parasitological research have resulted in new, promising insights in the fight of parasite versus host. The "Encyclopedic Reference of Parasitology", which is the completely revised second edition of "Parasitology in Focus" gives a comprehensive review of the facts and trends in veterinarian and human parasitology. In addition to the authors of the first edition, several internationally renowned specialists have been added.The book is now an Encyclopedic Reference, with all keywords and terms arranged alphabetically in the form of standardised entries. This enables information to be accessed more directly and much faster. The enclosed CD-ROM includes the full texts and all illustrations from both volumes, all fully hyperlinked, and has the added advantage of allowing rapid electronic searching. Please note that this publication is available as print only OR online only OR print + online bundle. Save 75% when purchasing the bundle. For more information on the online version please type the publication title into the search box above, then click on the "eReference" version.

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Hemophilus Influenzae Protocols

Hemophilus Influenzae Protocols (Methods in Molecular Medicine)
by Mark A. Herbert (Editor), Derek W. Hood (Editor), E. Richard Moxon (Editor)

Product Details:
* Hardcover: 344 pages
* Publisher: Humana Press; 1 edition (September 25, 2002)
* Language: English
* ISBN-10: 0896039285

Book Description
In HaemophilusiInfluenzae Protocols, leading research scientists and infectious disease specialists detail in a readily reproducible format the major molecular and immunological techniques for exploring the pathogenicity of H. influenzae. Described with step-by-instructions to ensure robust and successful experimental results, the techniques cover plasmid analysis, proteomics, genomics, DNA array technology, gene expression, mutagenesis (transposon and nontransposon), and structural analysis. These methods illuminate how the bacterium causes disease, as well as how best to develop novel vaccines and antibiotics against the organism.

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E. coli: Shiga Toxin Methods and Protocols

E. coli: Shiga Toxin Methods and Protocols (Methods in Molecular Medicine)
by Dana Philpott (Editor), Frank Ebel (Editor)

Product Details:
* Hardcover: 368 pages
* Publisher: Humana Press; 1 edition (September 26, 2002)
* Language: English
* ISBN-10: 0896039390

Book Description
A multidisciplinary panel of leading experimentalists details the key protocols for the diagnosis and study of the pathogenesis of Shiga toxin-producing Escherichia coli (STEC) and its isolated cytotoxin (Stx). Described in step-by-step detail, these readily reproducible techniques range from those for the diagnosis and detection of STEC bacteria in patient and animal samples, to those for studying the cellular microbiology of STEC infections, especially host-pathogen interactions and the hemolysin of STEC. There are also protocols for studying the details of Shiga toxin (Stx) biology-from the purification of the toxin to the effects of Stx on various host cell functions-and for exploring STEC-mediated disease in various animal models.

http://rapidshare.com/files/308304/073-E.coli_Shiga_Toxin_Methods_and_Protocols.pdf

Guidelines for the Management of Sexually Transmitted Infections

Guidelines for the Management of Sexually Transmitted Infections
by World Health Organization (Other Contributor)

Product Details:
* Paperback: 91 pages
* Publisher: World Health Organization (December 2003)
* Language: English
* ISBN-10: 9241546263

Book Description
This newly revised publication provides new treatment recommendations for a comprehensive management of patients with sexually transmitted infections (STIs) in the broader context of control, prevention and care programmes for STIs and HIV. Covers both the syndromic approach to the management of patients with STI symptoms, and the treatment of specific STIs. Also provides information on the notification and management of sexual partners and on STIs in children.

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Microbial Threats to Health Emergence, Detection, and Response

Microbial Threats to Health Emergence, Detection, and Response: Emergence, Detection, and Response
by Institute of Medicine (Corporate Author), Mark S. Smolinski (Editor), Margaret A. Hamburg (Editor), Joshua Lederberg (Editor)

Product Details:
* Hardcover: 450 pages
* Publisher: National Academy Press (September 2003)
* Language: English
* ISBN-10: 030908864X

Book Description:
Following up on a high-profile 1992 report from the Institute of Medicine, text examines the current state of knowledge and policy pertaining to infectious diseases. Discusses the spectrum of microbial threats, factors in disease emergence, and the capacity of the United States to meet the challenges of microbial threats. DNLM: Communicable Diseases, Emerging--epidemiology.

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Clinical Neurovirology

Clinical Neurovirology (Neurological Disease and Therapy)
by Avindra Nath (Editor), Joseph R. Berger (Editor)

Product Details:
* Hardcover: 688 pages
* Publisher: Informa Healthcare (August 1, 2003)
* Language: English
* ISBN-10: 0824740815

Book Description:
This comprehensive reference analyses the basic science, clinical features, imaging, pathology and treatment of specific viral entities affecting the central nervous system (CNS), assisting professionals in their attempt to identify, examine and manage viral CNS infections and unravel the therapeutic and diagnostic challenges associated with viral CNS disorders, including HIV infection, West Nile encephalitis and Creuzfeldt-Jacob disease.

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Prion Biology and Diseases

Prion Biology and Diseases (Cold Spring Harbor Monograph Series)
by Stanley B. Prusiner (Editor)

Product Details:
* Hardcover: 800 pages
* Publisher: Cold Spring Harbor Laboratory Press; 2nd edition (December 2003)
* Language: English
* ISBN-10: 0879696931

Book Description:
Prion-related diseases constitute a unique category of illnesses that can be inherited, infectious, or sporadic. The ongoing saga of efforts to unravel the pathogenesis of prion diseases is one of the most fascinating accounts in recent medical science. This group of diseases seems to have dispelled two long-held convictions: that nucleic acids are always needed to encode biologic information transmitted from generation to generation, and that a protein of a given amino acid sequence can give rise only to one tertiary structure of biologic importance. Prion Biology and Diseases provides an authoritative review of the work on prions. The book is an essential introduction for anyone embarking on prion research and is also a useful reference for those already working in this field.
The prion, or proteinaceous infectious particle, is thought to be responsible for a wide range of diseases characterized clinically by dementia and neuropathologically by neuronal loss, spongiform change, astrocytosis, and varying degrees of amyloid deposition. Prion diseases in humans include Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, and kuru; diseases in animals include scrapie and bovine spongiform encephalopathy. The cause of these diseases is thought to be a conformational change in a normal cellular protein, PrP(sup C), which is transformed into an infectious protein called PrP(sup Sc) (the superscript Sc denotes scrapie). PrP(sup Sc) does not differ from PrP(sup C) in its amino acid sequence or post-translational modifications; unlike PrP(sup C), however, PrP(sup Sc) is insoluble and resistant to proteinase K digestion, and it has a larger (beta)-sheet content and a propensity to aggregate into fibrils.
Although prion diseases in humans have thus far been rare, they are among the best-characterized "conformational diseases." Hence, the mechanisms of and potential therapeutic approaches to prion diseases may be relevant to more common conformational disorders, such as Alzheimer's disease (in which the amyloid (beta)-peptide is deposited as amyloid), Parkinson's disease (involving (alpha)-synuclein deposition in Lewy bodies), and the many neurodegenerative conditions associated with increased CAG repeats (e.g., Huntington's disease). Another reason for the importance of prion diseases is the recent reports of the transmission of bovine spongiform encephalopathy to humans through contaminated meat and bone meal, a topic that is well reviewed in this book. Evidence suggests that bovine spongiform encephalopathy has crossed the species barrier and now infects humans, resulting in new-variant Creutzfeldt-Jakob disease. It is unclear whether these cases mark the beginning of a human epidemic in Europe similar to that of bovine spongiform encephalopathy or whether the number of cases will remain small, as occurred with iatrogenic Creutzfeldt-Jakob disease after exposure to cadaveric growth hormone.
Many questions about prions remain unanswered, and for the most part, they are thoroughly examined in this book. An important issue is the basis for prion strains. There are many distinct isolates of prions, each associated with a specific incubation time and with specific neuropathological and Western blot features. If the protein-only hypothesis is correct, then each PrP(sup Sc) strain has a different abnormal conformation. Another unanswered question concerns "protein X." Prusiner and his colleagues have hypothesized that there is a species-specific protein that facilitates the unfolding of PrP(sup C) and its refolding into nascent PrP(sup Sc). Similar to the nucleic acid some suggest is associated with the infectivity of prions, this protein remains unidentified. The concept of protein X as a "pathological chaperone" is similar to the proposed role of apolipoprotein E4 in Alzheimer's disease. An issue that also needs to be resolved is the inability to develop synthetic or recombinant PrP(sup Sc) that is infectious in vivo -- a crucial requirement for the final proof of the protein-only hypothesis.
This book is a testament to the tremendous contributions of Prusiner and his collaborators in the field of prion research. The majority of the 17 chapters are coauthored by Prusiner or one or more of his collaborators. The information is very well organized and consistent. Until the final questions about prions are answered, however, this will continue to be an area of great controversy.

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The Anthrax Letters: A Medical Detective Story

The Anthrax Letters: A Medical Detective Story
by Leonard A. Cole (Author)

Product Details:
* Hardcover: 267 pages
* Publisher: Joseph Henry Press (October 1, 2003)
* Language: English
* ISBN-10: 0309525845

Book Description:
On October 5, 2001, Bob Stevens, a 63-year-old photo editor for the tabloid newspaper the Sun, became the first confirmed bioterrorism fatality in the U.S. Over the next several weeks, nearly two dozen people were diagnosed with anthrax, five of whom died. Disentangling a coherent story from the snarl of conflicting reports, multi-agency responses, blaring headlines, empty leads and the shaky scientific data surrounding the anthrax attacks is no simple task, which makes Cole's accomplished book all the more impressive. As an expert on the intersection of politics and terrorism, Cole (The Eleventh Plague) takes the reader on a captivating, no-nonsense tour of America's public health system, where physicians, scientists and administrators work tirelessly to establish protocols and policies, task forces and education programs, emergency response strategies and stockpiles of vital medicines to safeguard the country from a potentially catastrophic bioterror event. The book also supplies the chilling details that the short-lived media flareup failed to convey-such as the durability of anthrax spores, which can lie dormant but remain lethal for hundreds of years; the contamination of massive postal facilities that remain unsafe even after multimillion-dollar clean-up efforts; the difficulties involved in diagnosing many anthrax cases, which can display ambiguous symptoms; and the persistent, residual effects of the disease. Without even a hint of sensationalism, this disquieting but hopeful book skillfully zeros in on the most crucial issues and scientific advances as well as the heroic individuals who averted disaster while under the intense glare of public scrutiny.

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The Germ Survival Guide

The Germ Survival Guide
by Kenneth Bock (Author), Steven Bock (Author), Nancy Faass (Author)

Product Details:
* Paperback: 256 pages
* Publisher: McGraw-Hill; 1 edition (August 1, 2003)
* Language: English
* ISBN-10: 0071400451

Book Description:
The ultimate guide to protection from everyday germs
From public toilets to pay phones, handshakes to hugs, burger joints to five-star restaurants, the possibility of germ-borne sickness lurks in every part of our world. More than ever, readers need professional guidance on how to protect themselves and their loved ones from infection. The Germ Survival Guide:
* Describes 80 common locales in which germ-borne diseases pose a threat
* Offers simple preventive measures, from removing hotel bedspreads to draining backyard birdbaths
* Tells readers how to recognize symptoms and get treatment
* Introduces readers to more than 100 types of bacteria, molds, and parasites
* Combines conventional medical techniques and natural measures to give readers a complete and effective health plan

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