Yeast Gene Analysis

Yeast Gene Analysis, Volume 36, Second Edition (Methods in Microbiology)
by Ian Stansfield (Editor), Mike Stark (Editor)

Product Details:
* Paperback: 650 pages
* Publisher: Academic Press; 2 edition (May 29, 2007)
* Language: English
* ISBN-10: 0123694795

Book Description
Focusing on Saccharomyces cerevisiae, the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies that have been developed since then such as microarray analysis of transcription, synthetic gene array studies, protein microarrays and chemical genetic approaches. It represents a valuable resource for any research laboratory using budding yeast as their experimental system in which to identify new yeast gene functions. The chapters are written in a readable style with useful background information, technical tips and specific experimental protocols included as appropriate, enabling both the novice and the experienced yeast researcher to adopt new procedures with confidence.

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Autophagy in Immunity and Infection: A Novel Immune Effector

Autophagy in Immunity and Infection: A Novel Immune Effector
by Vojo Deretic (Editor)

Product Details:
* Hardcover: 286 pages
* Publisher: Wiley-VCH (September 29, 2006)
* Language: English
* ISBN-10: 3527314504

Book Description
This first book to cover this new topic at the interface of cell biology, immunology and infection biology offers a unique insight as to how the innate and possibly the adaptive immune system are shaped by cellular mechanisms. Following a comprehensive introduction to autophagy, the work features cellular mechanisms and medical implications, structured according to all major pathogens, while also covering emerging infectious diseases, such as tuberculosis. Edited by one of the authors of a groundbreaking paper on this topic.

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The Art of Genes

The Art of Genes

ISBN: 0198503431
Title: The Art of Genes
Author: Enrico Coen
Publisher: Oxford University Press, USA
Publication Date: 1999-07-15
Number Of Pages: 386

Book Description:

How is a tiny fertilised egg able to turn itself into a human being? How can an acorn transform itself into an oak tree? Through a highly original synthesis of science and art, this book vividly describes the recent revolution in our understanding of how plants and animals develop. Drawing on a wide range of material — from flowers growing petals instead of sex organs, and flies that develop an extra pair of wings, to works by Leonardo and Magritte — it explains the language and meaning of genes, in an entertaining way that is both accurate and accessible to the general reader. It shows how an organism develops through an interactive dialogue in which there is no clear separation between plan and execution, much as an artist might paint a picture. By explaining how this process has arisen, the book arrives at fresh and exciting insights into the nature of evolution, development and human creativity.

A groundbreaking new way of looking at one of the last great mysteries of biology
Written by an author at the cutting edge of current research
The first broadly accessible synthesis of modern ideas in development, that is both entertaining and thought-provoking. A fundamentally new approach to looking at development and its relation to evolution and human creativity
A fresh synthesis of key ideas in science, art and philosophy
An integrated account of plant and animal biology.

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Advanced Bacterial Genetics: Use of Transposons and Phage for Genomic Engineering

Advanced Bacterial Genetics: Use of Transposons and Phage for Genomic Engineering, Volume 421 (Methods in Enzymology)
by Kelly T Hughes (Editor)

Product Details:
* Hardcover: 320 pages
* Publisher: Academic Press; 1 edition (February 27, 2007)
* Language: English
* ISBN-10: 0123737494

Book Description
The critically acclaimed laboratory standard for more than fifty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant todaytruly an essential publication for researchers in all fields of life sciences. This new volume presents methods related to the use of bacterial genetics for genomic engineering. The book includes sections on strain collections and genetic nomenclature; transposons; and phage.

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Environmental and Microbial Relationships

Environmental and Microbial Relationships (The Mycota)
by Christian P. Kubicek (Editor), Irina S. Druzhinina (Editor)

Product Details:
* Hardcover: 350 pages
* Publisher: Springer; 2nd ed. edition (October 2007)
* Language: English
* ISBN-10: 3540718397

Book Description
After the publication of Volume IV in 1997, the introduction of molecular methods into ecology led to significant new findings. Emphasizing these advances, the chapters for the second edition have been completely updated and revised. This volume provides insight into current research on fungal populations and communities. It focuses on fungal responses to the physical environment, interactions with other fungi, microorganisms and invertebrates, the role of fungi in ecosystem processes such as decomposition and nutrient cycling, and aspects of biogeography and conservation. Several chapters deal with various applications in, e.g. biological pest control, natural products discovery, and the degradation of toxic organic compounds. This is an invaluable source of information both for scientists who wish to update their knowledge of current progress and for graduate students interested in obtaining a first overview of this field of research.

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Streptomyces in Nature and Medicine: The Antibiotic Makers

Streptomyces in Nature and Medicine: The Antibiotic Makers
by David A. Hopwood (Author)

Product Details:
* Hardcover: 260 pages
* Publisher: Oxford University Press, USA; 1 edition (January 8, 2007)
* Language: English
* ISBN-10: 019515066X

Book Description
This is an insiders account of 50 years of genetic studies of the soil-inhabiting microbes that produce most of the antibiotics used to treat infections, as well as anti-cancer, anti-parasitic and immunosuppressant drugs. The book begins by describing how these microbes the actinomycetes were discovered in the latter part of the nineteenth century, but remained a Cinderella group until, in the 1940s, they shot to prominence with the discovery of streptomycin, the first effective treatment for tuberculosis and only the second antibiotic, after penicillin, to become a medical marvel. There followed a massive effort over several decades to find further treatments for infectious diseases and cancer, tempered by the rise of antibiotic resistance consequent on antibiotic misuse and over-use. The book goes on to describe the discovery of gene exchange in the actinomycetes in the context of the rise of microbial genetics in the mid-20th century, leading to determination of the complete DNA sequence of a model member of the group at the turn of the millennium. There follow chapters in which the intricate molecular machinery that adapts the organisms metabolism and development to life in the soil, including antibiotic production, is illuminated by the DNA blueprint. Then come an up-to-the minute account of the use of genetic engineering to make novel, hybrid, antibiotics, and a topical description of techniques to learn the roles of the thousands of genes in a genome sequence, throwing a powerful light on the biology of the organisms and their harnessing for increasing antibiotic productivity. In the final chapter we return to the mycobacteria that cause tuberculosis and leprosy, the first actinomycetes to be discovered, and how methodology, in part derived from the study of the streptomycetes, is being applied to understand and control these still deadly pathogens.

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Cytokines in the Genesis and Treatment of Cancer

Cytokines in the Genesis and Treatment of Cancer (Cancer Drug Discovery and Development)
by Michael A. Caligiuri (Editor), Michael T. Lotze (Editor)

Product Details:
* Hardcover: 484 pages
* Publisher: Humana Press; 1 edition (April 20, 2007)
* Language: English
* ISBN-10: 0896038203

Book Description
Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume’s first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress — both in animal models and humans — in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the Genesis and Treatment of Cancer brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field.

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Fundamentals of Protein Structure and Function

Book Description

Textbook for courses at both graduate and undergraduate level. Also for related courses in biochemistry, biochemistry lab, and methods. Contains comprehensive analytical description of structure, biophysics, and function of proteins. Also summarizes the techniques used to characterize protein and protein interactions.

Product Details

* Hardcover: 368 pages
* Publisher: Springer; 1 edition (September 13, 2007)
* Language: English
* ISBN-10: 0387263527
* ISBN-13: 978-0387263526

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Public Health Microbiology: Methods and Protocols

Public Health Microbiology: Methods and Protocols (Methods in Molecular Biology)
by John F. T. Spencer (Editor), Alicia L. Ragout de Spencer (Editor)

Product Details;
* Hardcover: 568 pages
* Publisher: Humana Press; 1 edition (May 20, 2004)
* Language: English
* ISBN-10: 1588291170

Book Description
A collection of readily reproducible laboratory methods for the determination of various pathogenic microorganisms, their effects, and possible measures that can be taken to counter them. For bacterial and viral pathogens, the authors give special attention to PCR methods for detecting genes resistant to tetracycline, for resistance in Salmonella enterica, and for identifying and typing Campylobacter coli. For fungi the authors offer methods for computerized analysis and typing of fungal isolates, for the isolation and enumeration of fungi in foods, and for the determination of aflatoxin and zearalenone. Other methods deal with hazard analysis, the use of disinfectants, microbiological analysis of cosmetics, microbiological tests for sanitation equipment in factories, and the uses of animals in studies of various characteristics of lactobacilli. Review articles address the spread of pathogens from livestock and poultry production, including the threat of prion-based diseases.

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Mild-to-Moderate Psoriasis

Mild-to-Moderate Psoriasis
by John Y.M. Koo (Editor), Mark G. Lebwahl (Editor), Chai Sue Lee (Editor)

Product Details:
* Hardcover: 296 pages
* Publisher: Informa Healthcare; 1 edition (August 21, 2006)
* Language: English
* ISBN-10: 0849337232

Book Description
A companion to Therapy of Moderate-to-Severe Psoriasis, Second Edition, this reference offers expert guidance on the management of psoriasis with chapters covering recent advances in combination therapy, topical corticosteroids, calcipotriene, and phototherapy. Offering a practical approach to the many forms of psoriasis, including those that are particularly difficult to treat-including palmar-plantar, scalp, inverse, and nail psoriasis-this source will serve as a must-have tool for every clinician caring for patients with these conditions.

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Antimicrobial Pharmacodynamics in Theory and Clinical Practice

Antimicrobial Pharmacodynamics in Theory and Clinical Practice (Infectious Disease and Therapy)
by Nightingale/Mur (Author)

Product Details:
* Hardcover: 416 pages
* Publisher: Informa Healthcare; 1st edition (January 15, 2002)
* Language: English
* ISBN-10: 0824705610

Book Description
This up-to-the-minute reference explores the pharmacodynamics of antimicrobials as well as the absorption, distribution, metabolism, and elimination of the major classes of antimicrobials-covering new agents such as ketolide antibiotics and highlighting the pharmacodynamic relationship between drug concentration and antimicrobial activity, as well as the relationship of pharmacodynamics to bacterial resistance. Contains specific examples and practical applications for the design of effective dosing regimens! Written by recognized experts in the field, Antimicrobial Pharmacodynamics in Theory and Clinical Practice describes · the pharmacodynamic properties of all major classes of antibiotics · parameters for microbiological activity of antimicrobial agents such as minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) · serum/tissue protein binding and penetration rates · differences between in vivo and in vitro postantibiotic effects (PAE) · and more! With nearly 1000 references, tables, drawings, and illustrations, Antimicrobial Pharmacodynamics in Theory and Clinical Practice is a state-of-the-art reference for infectious disease specialists, pulmonologists, pharmacists, pharmacologists, microbiologists, biological chemists, epidemiologists, internists, and students in these disciplines.

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Antiviral Nucleosides: Chiral Synthesis and Chemotherapy

Antiviral Nucleosides: Chiral Synthesis and Chemotherapy
by C.K. Chu (Editor)

Product Details:
* Hardcover: 268 pages
* Publisher: Elsevier Science; 1 edition (October 15, 2003)
* Language: English
* ISBN-10: 0444513191

Book Description
• Up-to-date review on the chemistry and biology of nucleosides
• Modern synthetic methodology
• Comprehensive coverage of antiviral nucleosides
This book summarizes the recent advances in nucleosides chemistry and chemotherapy over the past 10-15 years. It covers recently discovered nucleoside antiviral agents, their therapeutic aspects and biochemistry, and also extensive reviews on their chiral synthesis.

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Current Diagnosis & Treatment of Sexually Transmitted Diseases

Current Diagnosis & Treatment of Sexually Transmitted Diseases
by Jeffrey D. Klausner (Author), III, Edward W. Hook (Author)

Product Details:
* Paperback: 400 pages
* Publisher: McGraw-Hill Medical; 1 edition (April 16, 2007)
* Language: English
* ISBN-10: 0071456066

Book Description
Get problem-oriented and disease-specific guidance in treating STDs-in one quick-access source
Featuring the trusted, practical format of the CURRENT series, this authoritative, quick-access guide delivers a top-to-bottom overview of STDs commonly encountered in clinical practice. The book begins with an insightful introduction to the field that emphasizes the patient-doctor relationship, and then explores clinical problems with STDs in terms of diagnostic, management, and treatment considerations.
Features
* A-to-Z, up-to-the-minute coverage of common STDs-filled with crucial point-of-care guidelines
* A focus on prevention interventions, including counseling, in recognition of the need to change high-risk sexual behaviors
* Practical diagnostic algorithms that summarize key protocols and facilitate patient management
* Detailed, easy-to-locate treatment tables that list specific drugs (generic and trade names), doses, and schedules
* A thought-provoking final chapter that includes a brief discussion of the latest STD research, plus unresolved questions and future concerns
* Useful appendices that include diagnostic protocols, treatment tables, and websites for further information.

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Restriction Endonucleases

Restriction Endonucleases (Nucleic Acids and Molecular Biology)
by Alfred M. Pingoud (Editor)

Product Details:
* Hardcover: 443 pages
* Publisher: Springer; 1 edition (December 16, 2004)
* Language: English
* ISBN-10: 3540205020

Book Description:
Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.

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DNA - The Secret of Life - Watson, James

DNA. The Secret of Life - Watson, James

It's a must. If you are new to the subject, start here. Also, there is print version with a very better quality than the pdf file, so, buy it! The man has 82 years old and is one of the father of function and structure of the DNA. Hope you enjoy it.

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Imaging Cellular and Molecular Biological Functions

Imaging Cellular and Molecular Biological Functions (Principles and Practice)
by Spencer L. Shorte (Editor), Friedrich Frischknecht (Editor)

Product Details:
* Hardcover: 435 pages
* Publisher: Springer; 1 edition (October 2007)
* Language: English
* ISBN-10: 3540713301

Book Description
“Imaging Cellular and Molecular Biological Function” provides a unique selection of essays by leading experts, aiming at scientist and student alike who are interested in all aspects of modern imaging, from its application and up-scaling to its development. The chapter content ranges from the basic through to complex overview of method and protocols, and there is also practical and detailed “how-to” content on important, but rarely addressed topics. This first edition features all-colour-plate chapters and a unique continuously updated website forum where contributors and readers share software utilities described herein including a limited license version of the imaging platform management software “PPMS” version 1.0 release, plus relevant new publications and links to other important resources.

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Cellular and Molecular Immunology

Cellular and Molecular Immunology, Updated Edition
by Abul K. Abbas (Author), Andrew Lichtman (Author)

Product Details:
* Paperback: 562 pages
* Publisher: Saunders; 5 edition (February 25, 2005)
* Language: English
* ISBN-10: 1416023895

Book Description:
This highly acclaimed text is now more up to date than ever! The Updated 5th Edition features new information and free access to a full-text online edition, images, animations, and much more at the brand-new STUDENT CONSULT website. Readers will continue to enjoy the current, concise, and straightforward approach to the field that made previous editions so popular. Theyll understand the experimental observations that underlie the science of immunology at the molecular, cellular, and whole organism leveland explore the conclusions that can be drawn from those observations.

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Molecular Basis of Human Nutrition (2003)

This book is aimed at first or second year undergraduates, or taught master’s students, who are studying nutrition as part of a degree in molecular life sciences, health sciences or medicine, including single honours nutrition students. It is intended to supplement the larger nutrition textbooks with greater emphasis on the molecular and metabolic basis of nutrition. It focuses on the biochemical functions of the essential nutrients and the physiological consequences of deficient and excessive intakes. These are described within the context of normal human diets and the requirements for health. Consideration is also given to the other biologically active materials within foods, and to the role of diet in multifactorial diseases. The book focuses on human nutrition, although there areinstances where comparisons with, or examples from, the nutrition of other mammalian species will be mentioned to help in the understanding of basic nutritional principles. It is assumed that readers will have studied, or will be studying concurrently, first year undergraduate modules in general biochemistry and mammalian physiology. The book is based on our experience of many years of research and teaching in nutrition.

Tom Sanders and Peter Emery
King’s College London

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Viral Regulatory Structures and Their Degeneracy

Viral Regulatory Structures and Their Degeneracy (Santa Fe Institute Studies in the Sciences of Complexity Lecture Notes)
by Gerald Myers (Editor)

Product Details:
* Paperback: 264 pages
* Publisher: Westview Press (November 1, 1997)
* Language: English
* ISBN-10: 0201328224

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Heat Shock Proteins: Potent Mediators of Inflammation and Immunity

Heat Shock Proteins: Potent Mediators of Inflammation and Immunity
by Alexzander A.A. Asea (Editor), Antonio De Maio (Editor)

Product Details:
* Hardcover: 357 pages
* Publisher: Springer; 1 edition (August 17, 2007)
* Language: English
* ISBN-10: 1402055846

Book Description
Heat Shock Proteins: Potent Mediators of Inflammation and Immunity currently provides the most up-to-date review on new mechanisms and provides exciting insights into how heat shock proteins modulates the hosts immune response. Written by leaders in the field of heat shock protein immunobiology, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which heat shock proteins activate immune responses and provides answers as to its biological significance to the host. From the early stages of binding and receptors-mediated signalling, to new paradigms by which heat shock proteins are released into the circulation, to antigen processing and presentation, and finally to the immune response itself this book is a must read for graduate and postgraduates in the field of Biology (plant and mammal), Biochemistry (pro- and eukaryotic), Immunology, Microbiology, Exercise Medicine, Physiology, Inflammatory diseases, Autoimmunity, Pharmacology and Pathology.

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Microscopic images transmitted by mobile cameraphone

Microscopic images transmitted by mobile cameraphone

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Transactions of the Royal Society of Tropical Medicine and Hygiene (2007) 101, 1053—1055.

A novel application of mobile cameraphone technology is the capture and transmission of images directly from the eyepiece of an ordinary laboratory microscope. The only equipment required is a spacer that allows the mobile phone camera to be held steady at the correct distance from, and parallel to, the microscope eyepiece lens. I used a plastic bottle cap, 35mm in diameter and 13mm deep, with an aperture about the diameter of the eyepiece lens (20mm) cut out of it. When the microscopic field to be captured is in focus, the spacer, cupped against the microscope eyepiece, is sandwiched between the camera and the eyepiece. By viewing the phone display and carefully adjusting the camera position, the image is centred, refocused if necessary, and captured. It can then be transmitted directly to another mobile phone or, ideally, to a computer, where it can be enlarged and enhanced, for expert opinion and permanent record. The resolution and colour reproduction of the image is limited by the camera’s quality. I used a basic mobile phone camera with a resolution of 640×480 pixels. This is sufficient to transmit images of objects of moderate size, such as a malaria gametocyte, or trypanosomes on a Giemsa-stained blood film, but not very small or subtle microscopic detail. However, mobile cameraphones are becoming ever cheaper and more sophisticated, with high resolution, zoom lenses, autofocus and video capture commonplace. The ubiquity of mobile phone networks will allow application of this simple technique in many situations where the dedicated and expensive microscope, camera, software, and computer network required for conventional telemedicine do not exist; for example, in rural diagnostic laboratories in developing countries.

Hodgson - A Textbook of Modern Toxicology 3e

Hodgson - A Textbook of Modern Toxicology 3e

Product Details:
* Hardcover: 584 pages
* Publisher: Wiley-Interscience; 3 edition (February 27, 2004)
* Language: English
* ISBN-10: 047126508X

Book Description
Toxicology is the science of poisons, embracing the physical and chemical study of all the known poisonous substances, as well as the methods of testing for them, their action on the living body, and the postmortem results they occasion. The Third Edition of this benchmark text once again proves the most authoritative resource on the subject for both students and practicing professionals.

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Heldt - Plant Biochemistry 3e

Heldt - Plant Biochemistry 3e

Product Details:
* Hardcover: 656 pages
* Publisher: Academic Press; 3 edition (September 2, 2004)
* Language: English
* ISBN-10: 0120883910

Book Description
Toxicology is the science of poisons, embracing the physical and chemical study of all the known poisonous substances, as well as the methods of testing for them, their action on the living body, and the postmortem results they occasion. The Third Edition of this benchmark text once again proves the most authoritative resource on the subject for both students and practicing professionals.

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Molecular Diagnostics: Fundamentals, Methods, & Clinical Applications

Molecular Diagnostics: Fundamentals, Methods, & Clinical Applications
by Lela, Ph.D. Buckingham (Author), Maribeth L., Ph.D. Flaws (Author)

Product Details:
* Paperback: 462 pages
* Publisher: F. A. Davis Company; 1 edition (May 15, 2007)
* Language: English
* ISBN-10: 0803616597

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New Insights in Medical Mycology

New Insights in Medical Mycology
by Kevin Kavanagh (Editor)

Product Details:
* Hardcover: 304 pages
* Publisher: Springer; 1 edition (October 2007)
* Language: English
* ISBN-10: 1402063962

Book Description
Although the means of diagnosing and treating fungal infections have improved greatly over the last decade fungi still represent a serious threat to the health of immunocompromised and immunodeficient patients. The aim of this book is to give an in-depth assessment of our current understanding of the Biology of the main fungal pathogens and how they interact with the host’s immune response. Each Chapter focuses on a specific fungal pathogen or group of pathogens and examines their biology and the factors that allow the fungus colonise and disseminate within the host. In addition each Chapter gives an indication of the challenges that remain to be tackled over the next 5 – 10 years in increasing our understanding of fungal pathogenicity. Each chapter is written by internationally recognized experts and this has ensured that the book is as comprehensive and authoritative a text as is possible to assemble.

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Molecular Biology of the Gene, Fifth Edition

Molecular Biology of the Gene, Fifth Edition
by James D. Watson (Author), Tania A. Baker (Author), Stephen P. Bell (Author), Alexander Gann (Author), Michael Levine (Author), Richard Losick (Author)

The long-awaited new edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA double-helix. Twenty-one concise chapters, co-authored by five highly respected molecular biologists, provide current, authoritative coverage of a fast-changing discipline, giving both historical and basic chemical context. Divided into four parts: Genetics and Chemistry, Central Dogma, Regulation, and Methods. For college instructors, students, and anyone interested in molecular biology and genetics.

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Microscopic images transmitted by mobile cameraphone

Microscopic images transmitted by mobile cameraphone

hi all, i found this article intresting. do write your comments.

Transactions of the Royal Society of Tropical Medicine and Hygiene (2007) 101, 1053—1055.

A novel application of mobile cameraphone technology is the capture and transmission of images directly from the eyepiece of an ordinary laboratory microscope. The only equipment required is a spacer that allows the mobile phone camera to be held steady at the correct distance from, and parallel to, the microscope eyepiece lens. I used a plastic bottle cap, 35mm in diameter and 13mm deep, with an aperture about the diameter of the eyepiece lens (20mm) cut out of it. When the microscopic field to be captured is in focus, the spacer, cupped against the microscope eyepiece, is sandwiched between the camera and the eyepiece. By viewing the phone display and carefully adjusting the camera position, the image is centred, refocused if necessary, and captured. It can then be transmitted directly to another mobile phone or, ideally, to a computer, where it can be enlarged and enhanced, for expert opinion and permanent record. The resolution and colour reproduction of the image is limited by the camera’s quality. I used a basic mobile phone camera with a resolution of 640×480 pixels. This is sufficient to transmit images of objects of moderate size, such as a malaria gametocyte, or trypanosomes on a Giemsa-stained blood film, but not very small or subtle microscopic detail. However, mobile cameraphones are becoming ever cheaper and more sophisticated, with high resolution, zoom lenses, autofocus and video capture commonplace. The ubiquity of mobile phone networks will allow application of this simple technique in many situations where the dedicated and expensive microscope, camera, software, and computer network required for conventional telemedicine do not exist; for example, in rural diagnostic laboratories in developing countries.

Principles of Molecular Regulation

Principles of Molecular Regulation
by P. Michael Conn (Editor), Anthony R. Means (Editor)

Product Details:
* Hardcover: 474 pages
* Publisher: Humana Press; 1st edition (August 15, 2000)
* Language: English
* ISBN-10: 0896036308

Book Description:

P. Michael Conn and Anthony Means have successfully assembled a panel of leading investigators to provide an integrated review of the key areas-membrane receptor-initiated cell signaling and nuclear-receptor initiated gene regulation. Chosen for the excellence of their research, these distinguished authors illuminate the molecular machinery underlying the regulatory processes of cells. In addition to their comprehensive review of the signaling mechanisms involving cell surface receptors, nuclear receptors, and ion channels, they detail the roles of calcium, lipids, cyclic AMP, protein kinases, and protein phosphatases. Capturing the excitement now present at this vibrant union of molecular biology, cell biology, and endocrinology, Principles of Molecular Regulation constitutes a major new resource for understanding the many and complex elements of biological regulation. Its up-to-date critical synthesis is certain to prove of high value to all basic and clinical investigators working with these processes today.

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Diseases and Disorders - AIDS

Diseases and Disorders - AIDS (Diseases and Disorders)
by Sudipta Bardhan-Quallen (Author)

Product Details:
* Board book: 112 pages
* Publisher: Lucent Books; 1 edition (July 30, 2004)
* Language: English
* ISBN-10: 1590184041

Bokk Description:
Succinct yet informative, this entry in the Understanding Diseases and Disorders series defines HIV and AIDS, explains the spread of HIV and the treatment of both HIV and AIDS, and discusses related scientific and humanitarian efforts around the world. Medical descriptions are clear, with challenging vocabulary highlighted for glossary cross-referencing, and statistics are current and startling. Well-chosen quotations from patients put a human face on the disease; in some, children (including Ryan White) describe their symptoms and setbacks; elsewhere, teens speak honestly about how they contracted the disease. A concluding chapter will leave many young readers discouraged by the inability of developing countries to procure needed drugs but cautiously hopeful about the progress of researchers and social activists.

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Medical Microbiology, Mims

Medical Microbiology, Updated Edition: With STUDENT CONSULT Online Access
by Cedric Mims (Author), Hazel Dockrell (Author), Richard Goering (Author), Ivan Roitt (Author), Derek Wakelin (Author), Mark Zuckerman (Author)

Product Details:
* Paperback: 660 pages
* Publisher: Mosby; 3 edition (November 18, 2004)
* Language: English
* ISBN-10: 0323035752

Book Description
Medical Microbiology has been improved and updated to keep it at the forefront of microbiological teaching practice. The clinically relevant, systems-based approach has been retained so as to emphasise the microbiology of the agents causing disease and the diseases affecting individual organ systems.
Over 250 color diagrams explain difficult concepts while color clinical photographs appear alongside the microbiology, stressing the clinical relevance of the science.
This book opens with an expanded basic introduction to viruses, bacteria, fungi and parasites. Then the immunology of the host is considered (again in more detail than in previous editions) before looking at the complex conflicts between host and invading agent. The clinical manifestations of these conflicts are explored within a systems-based context before concluding with a re-organised survey of microbiological diagnosis and control.
Throughout, attractive design features are used to highlight core information and make study and review that bit easier: Chapter Introductions, Key Facts Boxes, case-based Review Questions, new Microbiology Lessons and Summary Headings throughout make Medical Microbiology a pleasure to read.

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Industrial Applications of Electron Microscopy

Industrial Applications of Electron Microscopy (Encyclopedia of Library & Information Science)
by Zhigang Li (Author)

Product Details:
* Hardcover: 640 pages
* Publisher: CRC (December 4, 2002)
* Language: English
* ISBN-10: 0824708288

Book Description:
Providing proven strategies for solutions to research, development, and production dilemmas, this reference details the instrumentation and underlying principles for utilization of electron microscopy in the manufacturing, automotive, semiconductor, photographic film, pharmaceutical, chemical, mineral, forensic, glass, and pulp and paper industries. The book covers safety, calibration, and troubleshooting techniques, as well as methods in sample preparation and image collection, interpretation, and analysis. It includes contributions from microscopy experts based at major corporations and scientists from universities and major research centers.

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Microbial Sulfur Metabolism

Microbial Sulfur Metabolism
by Christiane Dahl (Editor), Cornelius G. Friedrich (Editor)

Product Details:
* Hardcover: 330 pages
* Publisher: Springer; 1 edition (October 2007)
* Language: English
* ISBN-10: 3540726799

Book Description
In nature, sulfur occurs in many different oxidation states and is one of the most versatile elements in life. It is an integral part of many important cell constituents, such as the amino acids cysteine and methionine, and many sulfur compounds serve as the basis for energy-related processes in prokaryotes. In recent years, new methods have been applied to study the biochemistry and molecular biology of reactions of the global sulfur cycle, the microorganisms involved and their physiology, metabolism and ecology. These activities have uncovered fascinating new insights for the understanding of aerobic and anaerobic sulfur metabolism.

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Current Protocols in Immunology

Current Protocols in Immunology (All volumes togather)

Product Details:
*Print ISSN: 1934-3671
*Online ISSN: 1934-368X
*Pages:4476
*Lanuage: English

Book Description
Current Protocols in Immunology is a "best-practices" collection that provides comprehensive coverage of immunological methods from classic to the most cutting edge: the most sophisticated protocols in immunology today.
* covers the latest in antibody detection and preparation, molecular immunology, innate immunity, tumor immunology, engineering immune molecules and receptors, and more.
* includes a recently-added chapter on sources and proven methods for isolation and characterization of stem and progenitor cells, as well as animal models for analyses.
* offers valuable reference information in five extensive appendices, including commonly used reagents, equipment and techniques; and a full appendix devoted to the CD system of leukocyte surface molecules.

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Yellow Fever Vaccinating Centres for International Travel

Yellow Fever Vaccinating Centres for International Travel: Situation as on 1 January 1991
by World Health Organization (Author)

Product Details:
* Paperback: 82 pages
* Publisher: World Health Organization (February 1991)
* Language: English
* ISBN-10: 9240580123

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Introduction to Molecular Biology

Introduction to Molecular Biology
by Peter Paolella (Author)

Product Details:
* Paperback: 320 pages
* Publisher: McGraw-Hill Science/Engineering/Math; 1 edition (August 1, 1997)
* Language: English
* ISBN-10: 0697209393

Book Description
Introduction to Molecular Biology focuses on molecular biology concepts and less on expanded data and themes. It presents a solid framework of concepts to better prepare students for more detailed courses in molecular biology and genetics. Written for science majors, this introductory, one-semester molecular biology text is designed for a sophomore-level course and assumes general biology and chemistry courses as a prerequisite.

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Parasitic Diseases in Water Resources Development

Parasitic Diseases in Water Resources Development
by World Health Organisation (Author)

Product Details:
* Paperback: 162 pages
* Publisher: World Health Organization (May 1, 1993)
* Language: English
* ISBN-10: 9241561556

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Sepsis: New Insights, New Therapies

Sepsis: New Insights, New Therapies, (Novartis Foundation Symposia)
by Novartis Foundation (Author)

Product Details:
* Hardcover: 302 pages
* Publisher: Wiley; 1 edition (March 23, 2007)
* Language: English
* ISBN-10: 0470027983

Book Description
Sepsis: New Insights, New Therapies brings together contributions from an international group of experts in diverse fields to consider how the various pathways implicated in early and late sepsis interact, with a particular emphasis on novel concepts and potential new therapeutic approaches. Topics covered include adaptive immunity, inflammation, neuroendocrinology, bioenergetics and metabolism. Several chapters in the latter half of the book are particularly concerned with treatment strategies involving modulation of the neuroendocrine response.
* Addresses the frequent, but under-recognised condition of sepsis and discusses new ways to prevent and treat it
* Describes numerous pharmacological approaches to therapy for early and late sepsis
* Includes detailed discussion of the various physiological systems implicated in sepsis
* Presents an international perspective, featuring contributions from experts from laboratories worldwide involved in the study of sepsis.

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Medical Immunology

Medical Immunology, Sixth Edition
by Gabriel Virella (Editor)

Product Details
* Hardcover: 465 pages
* Publisher: Informa Healthcare; 6 edition (March 28, 2007)
* Language: English
* ISBN-10: 0849396964

Book Description:
With an abundance of illustrations, diagrams, and algorithms for a reader-friendly review of critical material, this Sixth Edition is fully updated and revised to clearly update and explore current diagnostic and clinical applications of immunology, as well as strategies for the modulation of immune response and the treatment of hypersensitivity, autoimmune response, and immune deficiency conditions. Organized into four sections that review clinical applications, methodological advances, immunological diseases, and cutting edge interventions, this guide leads readers through state-of-the-sciences technologies and demonstrates their implementation in day-to-day clinical practice.

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Microbial Ecology of Aerial Plant Surfaces

Microbial Ecology of Aerial Plant Surfaces
by M. J. Bailey (Editor), A. K. Lilley (Editor), T. M. Timms-Wilson (Editor), P. T. N. Spencer-Phillips (Editor)

Product Details:
* Hardcover: 315 pages
* Publisher: CABI Publishing (March 19, 2007)
* Language: English
* ISBN-10: 1845930614

Book Description
All aerial plant surfaces, including leaves, stems and flowers are inhabited by diverse assemblages of microorganisms, including filamentous fungi, yeasts, bacteria, and bacteriophages. These organisms have profound effects on plant health and thus impact on ecosystem and agricultural functions.
This book is based on proceedings from the 8th International Symposium on the mircobiology of aerial plant surfaces, held in Oxford University in 2005. This is a five yearly conference which brings together international scientists and provides a unique opportunity to discuss developments in this field.

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Helminth Control in School-age Children

Helminth Control in School-age Children
by A. Montresor (Author), World Health Organization (Author), D.W.T Crompton (Author), T.W. Gyorkos (Author), L. Savioli (Author)

Product Details:
* Paperback: 81 pages
* Publisher: World Health Organization (November 1, 2002)
* ISBN-10: 9241545569

Book Description
This book is a guide for planners and programme managers in the health and education sectors who are charged with implementing community-based programmes for control of soil-transmitted helminth and schistosome infections in school-age children.
Schistosomiasis and soil-transmitted helminth cause more than 150 000 deaths each year. In school-age populations in developing countries, intestinal helminth infections rank first among the causes of all communicable and noncommunicable diseases. This book describes an approach to the control of infections that is based on the periodic treatment of school-age children – a particularly high-risk group. Parasitological surveys of school population samples, allied to treatment programmes, can then be used as a basis for selecting an appropriate control strategy for the whole community.

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Systems Biological Approaches in Infectious Diseases

Systems Biological Approaches in Infectious Diseases (Progress in Drug Research)
by Helena I. Boshoff (Editor), Clifton E. Barry III (Editor)

Product Details:
* Hardcover: 358 pages
* Publisher: Birkhaueser; 1 edition (December 28, 2006)
* Language: English
* ISBN-10: 3764375663

Book Description
Systems biology is an emerging discipline that studies the underlying network structure and the dynamics of metabolism, cells or whole organisms. It aims to investigate all interacting components simultaneously and requires data from high throughput techniques. These data from the ""omic"" sciences are computed and used to build in silico models of biological systems that ultimately will prove to be an invaluable tool in drug development.
This book brings together the various fields of functional genomics and systems biology that provide information on metabolic function with a special emphasis on the identifcation of drug targets. It includes practical examples from the various ""omic"" sciences as well as theoretical examples of how integrated knowledge of these sciences can be applied to drug discovery. It is of interest to researchers in the pharmaceutical drug discovery environment, as well as those in the academic field with an interest in the functional application of the ""omic"" sciences.

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Rabies Control in Asia-Fourth International Symposium

Rabies Control in Asia-Fourth International Symposium on Rabies Control in Asia

Product Details:
* Hardcover: 275 pages
* Publisher: WHO
* Language: English
* ISBN-10: 2742003932

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The Papillomaviruses

The Papillomaviruses
by Robert Garcea (Editor), Daniel DiMaio (Editor)

Product Details:
* Hardcover: 420 pages
* Publisher: Springer; 1 edition (February 2, 2007)
* Language: English
* ISBN-10: 0387365222

Book Description
This volume offers a complete description of the current state of biology concerning the papillomavirus. It evaluates the carcinogenic risk to humans posed by infection with human papillomaviruses (HPVs). To date, more than 70 HPV types have been identified, of which over 15 have been reported in cervical cancer biopsies. Worldwide, cervical cancer is the second most common cancer in women, approximately 500,000+ new cases are diagnosed each year. This book also considers the possible involvement of HPV infection in cancers at other sites of the human body.

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Gastrointestinal Microbiology

Gastrointestinal Microbiology
by Arthur C. Ouwehand (Editor), Elaine E. Vaughan (Editor)

Product Details:
* Hardcover: 432 pages
* Publisher: Informa Healthcare; 1 edition (June 5, 2006)
* Language: English
* ISBN-10: 0824726413

Book Description:
This reference supplies a comprehensive and current overview of every aspect of gastrointestinal microbiota. Expertly written chapters cover conventional and molecular techniques for the study of differing microbial populations, as well as the analysis of microbial activity and interaction with host bodies. Illustrative and up-to-date, this source showcases how fluctuations in our diet, environment, and pharmaceutical intake affect microbial composition and behavior.

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Microbial Imaging

Microbial Imaging, Volume 34 (Methods in Microbiology)
by Tor Savidge (Editor), Charalabos Pothulakis (Editor)

Product Details:
* Hardcover: 282 pages
* Publisher: Academic Press (December 29, 2004)
* Language: English
* ISBN-10: 0125215347

Book Description
Recent advances in molecular technology have provided new microbial imaging tools, not only complementing more classical methods, but in many cases significantly enhancing the sensitivity and efficiency in which studies may be conducted. These technologies are applicable to a wide range of problems in contemporary microbiology, including strain selection, understanding microbial structure, function and pathophysiology, as well as in the development of anti-microbial agents and vaccines. This volume emphasizes detailed methodology, provides a theoretical background and lists potential applications of specific imaging tools.

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Reichman and Hershfield's Tuberculosis

Reichman and Hershfield's Tuberculosis: A Comprehensive, International Approach, Third Edition (Two-Volume Set) (Lung Biology in Health and Disease)
by Mario C. Raviglione (Editor)

Product Details:
* Hardcover: 1400 pages
* Publisher: Informa Healthcare; 3 edition (August 1, 2006)
* Language: English
* ISBN-10: 0849392713

Book Description
Thoroughly examining tuberculosis from historical, theoretical, and clinical perspectives, this Third Edition merges state-of-the-art research developments with principles of programmatic TB management. Each of the 50 chapters analyze current studies on TB mechanisms and treatment and will meet the needs of all who work in the field of TB control, whether in low-income, high-prevalence areas or in low-prevalence industrialized countries.

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Hepatitis Delta Virus

Hepatitis Delta Virus (Medical Intelligence Unit)
by Hiroshi Handa (Author), Yuki Yamaguchi (Author)

Product Details:
* Hardcover: 94 pages
* Publisher: Springer; 1 edition (April 25, 2006)
* Language: English
* ISBN-10: 0387322302

Book Description
Since its discovery in 1979, HDV has occupied a unique position in virus taxonomy. It does not belong to any of the estabhshed viral family but constitutes its own genus, deltavirus, whereas it does have significant similarity to viroids, subviral agents of higher plants. HDV RNA genome is smaller than any known animal virus genome, so small that it encodes only a single protein. Therefore, its propagation is largely dependent on factors supplied by host and another virus, hepatitis B virus (HBV). For example, HDV makes use of HBV s surface antigens for envelope proteins. HDV replicates through RNA-dependent RNA synthesis by cellular DNA-dependent
RNA polymerase(s). RNA editing by cellular enzyme(s) and RNA cleavage by viral ribozymes are also involved in the viral life cycle. From a medical point of view, patients infected with both HBV and HDV tend to develop more severe clinical symptoms than those infected with HBV alone. All these features make HDV unique and attractive, and its research over the last two decades has resulted in a number of findings that have wide implications beyond the immediate subject.

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Annual Reviews of Immunology

Annual Reviews of Immunology (1983-2007)

Of the 5831 journals assessed by impact factor by the ISI, the Annual Review of Immunology is ranked #1 (54.455), Annual Review of Biochemistry is ranked #2 (36.278), and over one-third of the Annual Reviews titles are in the top 100 regardless of category.

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Traditional Medicinal Plants and Malaria

Traditional Medicinal Plants and Malaria (Traditional Herbal Medicines for Modern Times, V. 4)
by Merlin Willcox (Editor), Gerard Bodeker (Editor), Philippe Rasoanaivo (Editor), Jonathan Addae-Kyereme (Editor)

Product Details:
* Hardcover: 552 pages
* Publisher: CRC (June 15, 2004)
* Language: English
* ISBN-10: 0415301122

Book Description:
Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The world's poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimalarial drugs. The first book to be published on this subject, Traditional Medicinal Plants and Malaria explores the evidence for the safety and efficacy of some of these traditional medicines, and presents practical guidelines for designing studies on traditional plant-based antimalarial medicines, mosquito repellents, and insecticides. Systematic reviews of the literature and consensus guidelines form the main body of the book. Ethnomedical, ethnobotanical, pharmacological, phytochemical, toxicological, and clinical aspects of herbal antimalarials are also reviewed. These are supplemented by case studies of the most well-known traditional antimalarials.

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Entry Inhibitors in HIV Therapy

Entry Inhibitors in HIV Therapy (Milestones in Drug Therapy)
by Jacqueline D. Reeves (Editor), Cynthia A. Derdeyn (Editor)

Product Details:
* Hardcover: 200 pages
* Publisher: Birkhäuser Basel; 1 edition (July 2007)
* Language: English
* ISBN-10: 3764377828

Book Description
Entry Inhibitors in HIV Therapy details the current status of this relatively new and very dynamic class of inhibitors, appealing to both the clinician and basic research scientist. A unique overview of obstacles and accomplishments is presented. The book features chapters that explain the challenges of high sequence diversity in the viral envelope gene for the development and use of entry inhibitors, the clinical utility of virus phenotyping, the development of this class of inhibitors as microbicidal therapy, and the success story of enfuvirtide from the bench to FDA approval. Both basic research findings and results of clinical studies are covered and linked together by a diverse panel of experts in the field.

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Interferon:: The 50th Anniversary

Interferon:: The 50th Anniversary (Current Topics in Microbiology and Immunology)
by Paula M. Pitha (Editor)

Product Details:
* Hardcover: 335 pages
* Publisher: Springer; 1 edition (July 2007)
* Language: English
* ISBN-10: 354071328X

Book Description
Over the last half of century interferon (IFN), originally discovered as an antiviral protein, has developed from an inhibitor of viral replication to a major force in the antiviral response. Initially studied only by few virologists, IFN was generally considered as a poorly defined protein of limited importance. The development of molecular techniques lead to the identification of a family of IFN genes and has shown an unexpected complexity of type I IFN genes and their expression. Presently, some aspects of the of the pathogen mediated induction of IFN gene expression are understood at molecular level, while others are still at the stage of description. Both Toll like receptors and cytoplasmic RNA helicases were shown to recognize viral nucleic acids and the basis of a distinct recognition of viral nucleic acids from the cellular ones are emerging. Important insights on the virus recognition entity, leading to the expression of interferon and interferon induced genes, have been made in the recent year, which are challenging the accepted concept of the critical role of dsRNA in IFN induction. The availability of genetically modified mice that are lacking either essential components of the interferon inducing pathway, or interferon signaling pathway fully confirmed the original idea, made soon after its discovery, that interferon is the first cellular defense against viral infection.

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Antimicrobial Therapy, An Issue of Medical Clinics

Antimicrobial Therapy, An Issue of Medical Clinics (The Clinics: Internal Medicine)
by Burke A. Cunha (Author)

Product Details:
* Hardcover: 240 pages
* Publisher: Saunders; 1 edition (December 16, 2006)
* Language: English
* ISBN-10: 1416038892

Book Description
Dr. Burke Cunha, one of the foremost experts in the field of infectious disease, has put together an outstanding comprehensive issue with an exceptional team of authors that covers the most important updates in antimicrobial therapy. Treatment of helicobacter pylori, clostridium difficile, macrolide resistant S. pneumonia, and serious systemic infectious is covered. Authors discuss a clinical approach to anitibiotic failure, prevention and control of resistance, drug interactions, and therapy in the penicillin allergic patient. Monotherapy versus combination therapy, bacteriostatic versus bactericidal therapy, and in vitro susceptibility testing versus in vivo effectiveness are also covered. The issue also updates the reader on new uses for older antibiotics.

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Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery

Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery and Development)
by Dev P. Arya (Author)

Product Details:
* Hardcover
* Publisher: Wiley-Interscience (June 29, 2007)
* Language: English
* ISBN-10: 047174302X

Book Description:
During the last twenty years, there have been numerous advances in the understanding of the chemistry, biochemistry, and recognition of aminoglycosides. This has led to the development of novel antibiotics and opened up new therapeutic targets for intervention. This is the first book to provide a complete overview of recent advances in the field and explore their tremendous potential for drug discovery and rational drug design. With chapters written by one or more leading experts in their specialty areas, the book addresses the chemistry, biology, and toxicology of aminoglycosides.
Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery is a great resource for academic and industrial researchers in drug design and mechanism studies and for researchers studying antibiotic resistance, antibiotic design and synthesis, and the discovery of novel pharmaceuticals. It is also a valuable reference for graduate students in pharmacy, pharmaceutical science, biophysics, medicinal chemistry, and chemical biology.

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Rheumatoid Arthritis

Rheumatoid Arthritis
by E. William St. Clair (Author), David S Pisetsky (Author), Barton F Haynes (Author)

Product Details:
* Hardcover: 576 pages
* Publisher: Lippincott Williams & Wilkins (June 1, 2004)
* Language: English
* ISBN-10: 0781741491

Book Description:
This authoritative clinical reference provides comprehensive coverage of all aspects of rheumatoid arthritis. The basics of rheumatoid arthritis are thoroughly covered in order to provide a firm foundation for the main focus of the text: therapy and clinical management of the disease. Practitioners will find detailed information on both pharmacologic and nonpharmacologic courses of management, with special emphasis on the management of pain. More than 100 full-color illustrations provide clear visual support for the concepts in the text. Online references in each chapter, as well as an entire chapter on Web-based information resources, keep this book on the cutting edge of this rapidly evolving field.

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Microbiologia General (Spanish)

Microbiologia General - Nueva Edicion
by Hans G. Schlegel (Author)

Product Details;
* Paperback
* Publisher: Omega (August 2000)
* ISBN-10: 8428210306

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Treatments from Toxins: The Therapeutic Potential of Clostridial Neurotoxins

Treatments from Toxins: The Therapeutic Potential of Clostridial Neurotoxins
by Keith Alan Foster (Editor), Peter Hambleton (Editor), Clifford C. Shone (Editor)

Product Details:
* Hardcover: 312 pages
* Publisher: CRC; 1 edition (November 2, 2006)
* Language: English
* ISBN-10: 0849327091

Book Description
As little as two decades ago, deliberately injecting botulinum toxin into patients would have seemed foolhardy at best and criminal at worst. The increased clinical use of botulinum toxins has expanded the body of knowledge available on the structure and function of these proteins. This knowledge can be applied to topics as varied as therapies based on the endopeptidase activity of the toxins, vaccine development, protection against botulism, and vectors for neuronal drug delivery. Based on recent scientific and clinical information from top international authorities, Treatments from Toxins: The Therapeutic Potential of Clostridial Neurotoxins reviews the status of current research and development and identifies significant developments. Drawing on their vast experience in this field, the editors present the basic background of the bacteriology and genetics of the neurotoxigenic clostridia, a history of the discovery of the neurotoxins, and an overview of the tetanus and botulism diseases. The chapters detailing common medical applications of the toxins cover side effects and novel uses, including neuronal drug delivery strategies, and provide a fresh look at what can still be achieved. They also explore the toxins as potential threat agents and the advent of the therapeutic use of botulinum toxins. Highlighting the pitfalls, successes, and challenges that exist when engineering complex proteins, the book brings together the clinical and theoretical worlds. It presents a broad overview of the current status of botulinum research and its clinical applications.

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Pediatric Infectious Diseases Revisited

Pediatric Infectious Diseases Revisited (Birkhäuser Advances in Infectious Diseases)
by Horst Schroten (Editor), Stefan Wirth (Editor)

Product Details:
* Hardcover: 503 pages
* Publisher: Birkhäuser Basel; 1 edition (June 28, 2007)
* Language: English
* ISBN-10: 3764379979

Book Description
The successful prevention of childhood diseases like diphtheria, tetanus and pertussis has made a major contribution to the improvement of public health, and vaccines and a variety of drugs are amongst the most fruitful applications of 20th-century research. Today pediatric infectious disease research is closely interconnected with other disciplines. Understanding the biology of the causative agents and the pathogenesis of disease is an essential step in achieving control and elimination of the diseases. Starting with historical, epidemiological and sociocultural issues, the volume presents clinical as well as molecular biological aspects of pediatric infectious diseases. New insights into the pathogenesis of infection are presented and an update on diagnostics, prevention and treatment of pediatric viral, fungal and bacterial diseases provided. The role of emerging new pathogens is also highlighted. The book aims at an interdisciplinary audience of clinicians and non-clinicians: pediatricians, infectious disease researchers, virologists, microbiologists, public health politicians and university libraries.

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Cholera, Chloroform and the Science of Medicine: A Life of John Snow

Cholera, Chloroform and the Science of Medicine: A Life of John Snow
by Peter Vinten-Johansen (Author), Howard Brody (Author), Nigel Paneth (Author), Stephen Rachman (Author), Michael Russell Rip (Author)

Product Details:
* Hardcover: 454 pages
* Publisher: Oxford University Press, USA (April 23, 2003)
* Language: English
* ISBN-10: 019513544X

Book Description:

The product of six years of collaborative research, this fine biography offers new interpretations of a pioneering figure in anesthesiology, epidemiology, medical cartography, and public health. It modifies the conventional rags to riches portrait of John Snow by synthesizing fresh information about his early life from archival research and recent studies. It explores the intellectual roots of his commitments to vegetarianism, temperance, and pure drinking water, first developed when he was a medical apprentice and assistant in the north of England. The authors argue that all of Snow's later contributions are traceable to the medical paradigm he imbibed as a medical student in London and put into practice early in his career as a clinician: that medicine as a science required the incorporation of recent developments in its collateral sciences--chiefly anatomy, chemistry, and physiology--in order to understand the causes of disease. Snow's theoretical breakthroughs in anesthesia were extensions of his experimental research in respiratory physiology and the properties of inhaled gases. Shortly thereafter, his understanding of gas laws led him to reject miasmatic explanations for the spread of cholera, and to develop an alternative theory in consonance with what was then known about chemistry and the physiology of digestion. Using all of Snow's writings, the authors follow him when working in his home laboratory, visiting patients throughout London, attending medical society meetings, and conducting studies during the cholera epidemics of 1849 and 1854. The result is a book that demythologizes some overly heroic views of Snow by providing a fairer measure of his actual contributions. It will have an impact not only on the understanding of the man but also on the history of epidemiology and medical science.

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Dendritic Neurotransmitter Release

Dendritic Neurotransmitter Release
by Mike Ludwig (Editor)

Product Details:
* Hardcover: 334 pages
* Publisher: Springer; 1 edition (December 8, 2004)
* Language: English
* ISBN-10: 0387229337

Book Description
This text will highlight the mechanisms and consequences of dendritic transmitter release, with an emphasis on the mechanisms that generate such processing and how these can induce state-dependent plasticity in the processing. This volume will be out of broad significance, expanding the understanding of the spectrum of dendritic mechanisms for neural processing. It will demonstrate that dendritic release that likely occurs throughout the brain is a key feature in the control of information transfer in neural networks, through cross-talk and autorcontrol by paracine/autocrine mechanisms

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Atopic Dermatitis

Atopic Dermatitis
by Thomas Bieber (Editor), Donald Y. M. Leung (Editor)

Product Details:
* Hardcover: 656 pages
* Publisher: Informa Healthcare (April 23, 2002)
* Language: English
* ISBN-10: 0824707427

Book Description
This reference explores the epidemiology, etiology, management, and pathophysiological mechanisms of atopic dermatitis and identifies potential genetic and environmental factors associated with allergic skin immune responses-compiling the latest research, diagnostic procedures, and therapeutic strategies for the prevention, control, and treatment of this chronic inflammatory disease. Written by leading experts in the field, Atopic Dermatitis addresses · the clinical features of atopic dermatitis (AD) · the role of antigen-presenting cells, T-cells, and keratinocytes in pathogenesis · food hypersensitivity and infections in children · the identification and elimination of exacerbating components · emerging anti-inflammatory agents for controlling AD · the importance of animal models · the effect of AD on the emotional development of patients Discussing the mounting prevalence of skin disease, as well as its social and economic impact, Atopic Dermatitis is a definitive and essential guide for dermatologists, allergists, immunologists, pharmaceutical and cosmetic chemists, internists, pediatricians, epidemiologists, and graduate and medical school students in these disciplines.

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Reese and Betts' A Practical Approach to Infectious Diseases

Reese and Betts' A Practical Approach to Infectious Diseases
by Robert F Betts (Author), Stanley W Chapman (Author), Robert L Penn (Author)

Product Details:
* Paperback: 1282 pages
* Publisher: Lippincott Williams & Wilkins; 5 edition (November 1, 2002)
* Language: English
* ISBN-10: 0781732816

Book Description
Now in its thoroughly revised, updated Fifth Edition, this handbook is a practical, easily accessible, and authoritative guide to the diagnosis and treatment of infectious diseases. Leading experts present realistic clinical approaches to infectious disease problems seen in hospital and outpatient settings and offer up-to-the-minute advice on antimicrobial use--including specific recommendations on dosages, routes of administration, and duration of therapy. Chapters are written in a user-friendly outline format that is ideal for quick reference. This edition includes complete information on new diseases, new antibiotics, and HIV antiviral agents.

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