Mandell's Principles and Practice of Infectious Diseases

Principles and Practice of Infectious Diseases: 2-Volume Set (Hardcover)
by Gerald L. Mandell, John E. Bennett, Raphael Dolin

Product Details
* Hardcover: 4000 pages
* Publisher: Churchill Livingstone; 6 edition (October 22, 2004)
* Language: English
* ISBN: 0443066434

JAMA May 11, 2005
"A beauty to behold . . . No other text comes close."

Widely acknowledged as the definitive reference source of its kind, Principles and Practice of Infectious Diseases is back - in a new 6th Edition! Authored by a "who's who" of experts from around the world, this 2-volume set encompasses all that is currently known about the epidemiology, aetiology, pathology, microbiology, immunology, and treatment of infectious agents. Completely revised and updated - and with a bold, new 4-colour format - it is a complete, essential compendium of knowledge on this vast and complex subject.

Table of Contents

VOLUME 1

Part I. Basic Principles in the Diagnosis and Management of Infectious Diseases

SECTION A. MICROBIAL VIRULENCE FACTORS
1. A Molecular Perspective of Microbial Pathogenicity
2. Microbial Adherence
3. Toxins

SECTION B. HOST DEFENSE MECHANISMS 4
4. Innate (General or Nonspecific) Host Defense Mechanisms
5. Human Genetics and Infection
6. Antibodies
7. Complement
8. Granulocytic Phagocytes
9. Cell-Mediated Defense against Infection
10. Nutrition, Immunity, and Infection
11. Evaluation of the Patient with Suspected Immunodeficiency

SECTION C. EPIDEMIOLOGY OF INFECTIOUS DISEASES
12. Epidemiologic Principles
13. Emerging and Re-emerging Infectious Disease Threats
14. Hospital Preparedness for Emerging and Highly Contagious Infections Diseases: Getting Ready for SARS or Whatever Comes Next

SECTION D.
15. The Clinician and the Microbiology Laboratory

SECTION E. ANTI-INFECTIVE THERAPY
16. Principles of Anti-infective Therapy
17. Molecular Mechanisms of Antibiotic Resistance in Bacteria
18. Pharmacokinetics and Pharmacodynamics of Anti-infective Agents
19. Penicillins
20. Cephalosporins
21. Other b-Lactam Antibiotics
22. b-Lactam Allergy
23. Fusidic Acid
24. Aminoglycosides
25. Tetracyclines and Chloramphenicol
26. Rifamycins
27. Metronidazole
28. Macrolides, Clindamycin, and Ketolides
29. Glycopeptides (Vancomycin and Teicoplanin), Streptogramins Quinupristin-Dalfopristin), and Lipopeptides (Daptomycin)
30. Polymyxins (Polymixin B and Colistin)
31. Oxazolidinones
32. Sulfonamides and Trimethoprim 33. Quinolones
34. Urinary Tract Agents: Nitrofurantoin and Methenamine
35. Topical Antibacterials
36. Antimycobacterial Agents
37. Systemic Antifungal Agents
38. Antiviral Drugs (Other Than Antiretrovirals)
39. Immunomodulators
40. Hyperbaric Oxygen
41. Agents Active against Parasites and Pneumocystis
42. Complementary and Alternative Medicines for Infectious Diseases
43. Antimicrobial Management and Cost Containment
44. Interpretating the Results of Clinical Trials on Antimicrobial Agents
45. Outpatient Intravenous Antibiotic Therapy
46. Tables of Antimicrobial Agent Pharmacology

PART II. Major Clinical Syndromes
SECTION A. FEVER
47. Temperature Regulation and the Pathogenesis of Fever
48. Fever of Unknown Origin
49. The Acutely Ill Patient with Fever and Rash

SECTION B. UPPER RESPIRATORY TRACT INFECTIONS
50. The Common Cold
51. Pharyngitis
52. Acute Laryngitis
53. Acute Laryngotracheobronchitis (Croup)
54. Otitis Externa, Otitis Media, and Mastoiditis
55. Sinusitis
56. Epiglottitis
57. Infections of the Oral Cavity, Neck, and Head

SECTION C. PLEUROPULMONARY AND BRONCHIAL INFECTIONS
58. Acute Bronchitis
59. Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, and Acute Exacerbations
60. Bronchiolitis
61. Acute Pneumonia
62. Pleural Effusion and Empyema
63. Lung Abscess
64. Chronic Pneumonia
65. Cystic Fibrosis

SECTION D. URINARY TRACT INFECTION
66. Urinary Tract Infections
SECTION E. SEPSIS
67. Sepsis, Severe Sepsis, and Septic Shock

SECTION F. INTERABDOMINAL INFECTION
68. Peritonitis and Intraperitoneal Abscesses
69. Infections of the Liver and Biliary System
70. Pancreatic Infections
71. Splenic Abscess
72. Appendicitis
73. Diverticulitis and Typhlitis

SECTION G. CARDIOVASCULAR INFECTIONS
74. Endocarditis and Intravascular Infections
75. Infections of Prosthetic Valves and Other Cardiovascular Devices
76. Prophylaxis of Infective Endocarditis
77. Myocarditis and Pericarditis
78. Mediastinitis

SECTION H. CENTRAL NERVOUS SYSTEM INFECTIONS
79. Approach to the Patient with Central Nervous System Infection
80. Acute Meningitis
81. Cerebrospinal Fluid Shunt Infections
82. Chronic Meningitis
83. Encephalitis, Myelitis, and Neuritis
84. Brain Abscess
85. Subdural Empyema, Epidural Abscess, and Suppurative Intracranial Thrombophlebitis

SECTION I. SKIN AND SOFT TISSUE INFECTIONS
86. Cellulitis and Subcutaneous Tissue Infections
87. Myositis
88. Lymphadenitis and Lymphangitis

SECTION J. GASTROINTESTINAL INFECTIONS AND FOOD POISONING
89. Principles and Syndromes of Enteric Infection
90. Esophagitis
91. Nausea, Vomiting, and Noninflammatory Diarrhea
92. Antibiotic-Associated Colitis
93. Inflammatory Enteritides
94. Enteric Fever and Other Causes of Abdominal Symptoms with Fever
95. Foodborne Disease
96. Tropical Sprue/Enteropathy
97. Whipple’s Disease

SECTION K. BONE AND JOINT INFECTIONS
98. Infectious Arthritis of Native Joints
99. Osteomyelitis 100. Infections with Prostheses in Bones and Joints

SECTION L. DISEASES OF THE REPRODUCTIVE ORGANS AND SEXUALLY TRANSMITTED DISEASES
101. Genital Skin and Mucous Membrane Lesions
102. Urethritis
103. Vulvovaginitis and Cervicitis
104. Infections of the Female Pelvis
105. Prostatitis, Epididymitis, and Orchitis

SECTION M. EYE INFECTIONS
105. Microbial Conjunctivitis
107. Microbial Keratitis
108. Endophthalmitis
109. Infectious Causes of Uveitis
110. Periocular Infections

SECTION N. HEPATITIS
111. Acute Viral Hepatitis
112. Chronic Viral Hepatitis

SECTION O. ACQUIRED IMMUNODEFICIENCY SYNDROME
113. Global Perspectives on Human Immunodeficiency Virus Infection and Acquired Immunodeficiency

Syndrome
114. Epidemiology and Prevention of Acquired Immunodeficiency Syndrome and Human Immunodeficiency

Virus Infection
115. Diagnosis of Human Immunodeficiency Virus Infection
116. The Immunology of Human Immunodeficiency Virus Infection
117. General Clinical Manifestations of Human Immunodeficiency Virus Infection (Including the Acute Retroviral Syndrome and Oral, Cutaneous, Renal, Ocular, and Cardiac Diseases)
118. Pulmonary Manifestations of Human Immunodeficiency Virus Infection
119. Gastrointestinal and Hepatobiliary Manifestations of Human Immunodeficiency Virus Infection
120. Neurologic Diseases Caused by Human Immunodeficiency Virus-1 and Opportunistic Infections
121. Malignancies in Human Immunodeficiency Virus Infection
122. Human Immunodeficiency Virus Infection in Women
123. Pediatric Human Immunodeficiency Virus Infection
124. Antiretroviral Therapy for Human Immunodeficiency Virus Infection
125. Management of Opportunistic Infections Associated with Human Immunodeficiency Virus Infection
126. Vaccines for Human Immunodeficiency Virus-1 Infection

SECTION P. MISCELLANEOUS SYNDROMES
127. Chronic Fatigue Syndrome Index, i


VOLUME 2

PART III. Infectious Diseases and Their Etiologic Agents

SECTION A. VIRAL DISEASES
128. Introduction to Viruses and Viral Diseases
129. Orthopoxviruses: Vaccinia (Smallpox Vaccine), Variola (Smallpox), Monkeypox, and Cowpox
130. Other Poxviruses That Infect Humans: Parapoxviruses, Molluscum Contagiosum, and Yatapox
131. Introduction to Herpesviridae
132. Herpes Simplex Virus
133. Varicella-Zoster Virus
134. Cytomegalovirus
135. Epstein-Barr Virus (Infectious Mononucleosis)
136. Human Herpesvirus Types 6 and 7
137. Kaposi’s Sarcoma−Associated Herpesvirus (Human Herpesvirus Type 8)
138. Herpes B Virus
139. Adenovirus
140. Papillomaviruses
141. JC, BK, and Other Polyomaviruses; Progressive Multifocal Leukoencephalopathy
142. Hepatitis B Virus and Hepatitis Delta Virus
143. Parvovirus B19
144. Orthoreoviruses and Orbiviruses
145. Coltiviruses and Seadornaviruses (Colorado Tick Fever)
146. Rotaviruses
147. Alphaviruses 148. Rubella Virus (German Measles)
149. Flaviviruses (Yellow Fever, Dengue, Dengue Hemorrhagic Fever, Japanese Encephalitis, West Nile Encephalitis, St. Louis Encephalitis, Tick-Borne Encephalitis)
150. Hepatitis C
151. Hepatitis G Virus and TT Virus
152. Coronaviruses, Including Severe Acute Respiratory Syndrome (SARS)–Associated Coronavirus
153. Parainfluenza Viruses
154. Mumps Virus
155. Respiratory Syncytial Virus
156. Human Metapneumovirus
157. Measles Virus (Rubeola)
158. Zoonotic Paramyxoviruses: Hendra, Nipah, and Menangle Viruses
159. Vesicular Stomatitis and Related Viruses
160. Rabdoviruses
161. Marburg and Ebola Virus Hemorrhagic Fevers
162. Influenza Virus
163. California Encephalitis, Hantavirus Pulmonary Syndrome, and Bunyavirid Hemorrhagic Fevers
164. Lymphocytic Choriomeningitis Virus, Lassa Virus, and the South American Hemorrhagic Fevers
165. Human T-Cell Lymphotropic Virus Types I and II
166. Human Immunodeficiency Viruses
167. Introduction to the Enteroviruses
168. Poliovirus
169. Coxsackieviruses, Echoviruses, and Newer Enteroviruses
170. Hepatitis A Virus
171. Rhinovirus
172. Noroviruses and Other Caliciviruses
173. Astroviruses and Picobirnaviruses 174. Hepatitis E Virus SECTION B. PRION DISEASES 175. Prions and Prion Diseases of the Central Nervous System (Transmissible Neurodegenerative Diseases)

SECTION C. CHLAMYDIAL DISEASES
176. Introduction to Chlamydial Diseases
177. Chlamydia trachomatis (Trachoma, Perinatal Infections, Lymphogranuloma Venereum, and Other Genital Infections)
178. Chlamydophila (Chlamydia) psittaci (Psittacosis)
179. Chlamydophila (Chlamydia) pneumoniae

SECTION D. MYCOPLASMA DISEASES
180. Introduction to Mycoplasma Diseases
181. Mycoplasma pneumoniae and Atypical Pneumonia
182. Genital Mycoplasmas: Mycoplasma genitalium, Mycoplasma hominis, and Ureaplasma urealyticum

SECTION E. RICKETTSIOSES AND EHRLICHIOSES
183. Introduction to Rickettsioses and Ehrlichioses
184. Rickettsia rickettsii and Other Spotted Fever Group Rickettsiae (Rocky Mountain Spotted Fever and Other Spotted Fevers)
185. Rickettsia akari (Rickettsialpox)
186. Coxiella burnetii (Q Fever)
187. Rickettsia prowazekii (Epidemic or Louse-Borne Typhus)
188. Rickettsia typhi (Murine Typhus)
189. Scrub Typhus
190. Ehrlichia chaffeensis (Human Monocytotropic Ehrlichiosis), Anaplasma phagocytophila (Human Granulocytotropic Anaplasmosis), and Other Ehrlichieae

SECTION F. BACTERIAL DISEASES
191. Introduction to Bacteria and Bacterial Diseases
192. Staphylococcus aureus (Including Staphylococcal Toxic Shock)
193. Staphylococcus epidermidis and Other Coagulase-Negative Staphylococci
194. Classification of Streptococci
195. Streptococcus pyogenes
196. Nonsuppurative Poststreptococcal Sequelae: Rheumatic Fever and Glomerulonephritis
197. Streptococcus pneumoniae
198. Enterococcus Species, Streptococcus bovis, and Leuconostoc Species
199. Streptococcus agalactiae (Group B Streptococcus)
200. Viridans Streptococci, Groups C and G Streptococci, and Gemella morbillorum
201. Streptococcus anginosus Group (or milleri Group or intermedius Group)
202. Corynebacterium diphtheriae
203. Other Coryneform Bacteria and Rhodococcus
204. Listeria monocytogenes
205. Bacillus anthracis (Anthrax)
206. Bacillus Species and Related Genera Other Than Bacillus anthracis
207. Erysipelothrix rhusiopathiae
208. Neisseria meningitidis
209. Neisseria gonorrhoeae
210. Moraxella (Branhamella) catarrhalis and Other Gram-Negative Cocci
211. Vibrio cholerae
212. Other Pathogenic Vibrios
213. Campylobacter jejuni and Related Species
214. Helicobacter pylori and Other Gastric Helicobacter Species
215. Enterobacteriaceae
216. Pseudomonas aeruginosa
217. Stenotrophomonas maltophilia and Burkholderia cepacia
218. Burkholderia pseudomallei and Burkholderia mallei: Melioidosis and Glanders
219. Acinetobacter Species
220. Salmonella Species, Including Salmonella typhi
221. Shigella Species (Bacillary Dysentery)
222. Haemophilus Infections
223. Brucella Species
224. Francisella tularensis (Tularemia)
225. Pasteurella Species
226. Yersinia Infections, Including Plague
227. Bordetella Species
228. Streptobacillus moniliformis (Rat-Bite Fever)
229. Legionnaires' Disease and Pontiac Fever
230. Other Legionella Species
231. Capnocytophaga
232. Infections Due to Bartonella Species, Including Cat-Scratch Disease
233. Calymmatobacterium granulomatis (Donovanosis, Granuloma Inguinale)
234. Other Gram-Negative Bacilli
235. Treponema pallidum (Syphilis)
236. Endemic Treponematoses
237. Leptospirosis
238. Borrelia Species (Relapsing Fever)
239. Borrelia burgdorferi (Lyme Disease, Lyme Borreliosis)
240. Spirillum minus (Rat-Bite Fever)
241. Anaerobic Infections: General Concepts
242. Clostridium tetani (Tetanus)
243. Clostridium botulinum (Botulism)
244. Gas Gangrene and Other Clostridium-Associated Diseases
245. Bacteroides, Prevotella, Porphyromonas, and Fusobacterium Species (and Other Medically Important Anaerobic Gram-Negative Bacilli)
246. Anaerobic Cocci
247. Anaerobic Gram-Positive Nonsporulating Bacilli
248. Mycobacterium tuberculosis
249. Mycobacterium leprae (Leprosy, Hansen’s Disease)
250. Mycobacterium avium Complex
251. Infections Due to Nontuberculous Mycobacteria
252. Nocardia Species
253. Agents of Actinomycosis

SECTION G. MYCOSES
254. Introduction to Mycoses
255. Candida Species
256. Aspergillus Species
257. Agents of Mucormycosis and Related Species
258. Sporothrix schenckii
259. Agents of Chromoblastomycosis
260. Agents of Mycetoma
261. Cryptococcus neoformans
262. Histoplasma capsulatum
263. Blastomyces dermatitidis
264. Coccidioides Species
265. Dermatophytosis and Other Superficial Mycoses
266. Paracoccidioides brasiliensis
267. Uncommon Fungi
268. Pneumocystis Species

SECTION H. PROTOZOAL DISEASES
269. Introduction to Protozoal Diseases
270. Entamoeba histolytica (Amebiasis)
271. Free-Living Amebas
272. Plasmodium Species (Malaria)
273. Leishmania Species: Visceral (Kala-Azar), Cutaneous, and Mucocutaneous Leishmaniasis
274. Trypanosoma Species (American Trypanosomiasis, Chagas’ Disease): Biology of Trypanosomes
275. Agents of African Trypanosomiasis (Sleeping Sickness)
276. Toxoplasma gondii
277. Giardia lamblia
278. Trichomonas vaginalis
279. Babesia Species
280. Cryptosporidiosis (Cryptosporidium hominis, Cryptosporidium parvum, and Other Species)
281. Cyclospora cayetanensis, Isospora belli, Sarcocystis Species, Balantidium coli, and Blastocystis hominis 282. Microsporidiosis

SECTION I. DISEASES DUE TO TOXIC ALGAE
283. Human Illness Associated with Harmful Algal Blooms

SECTION J. DISEASES DUE TO HELMINTHS
284. Introduction to Helminth Infections
285. Intestinal Nematodes (Roundworms)
286. Tissue Nematodes. Including Trichinosis, Dracunculiasis, and the Filariases
287. Trematodes (Schistosomes and Other Flukes)
288. Cestodes (Tapeworms)
289. Visceral Larva Migrans and Other Unusual Helminth Infections

SECTION K. ECTOPARASITIC DISEASES
290. Introduction to Ectoparasitic Diseases
291. Lice (Pediculosis)
292. Scabies
293. Myiasis and Tungiasis
294. Mites (Including Chiggers)
295. Ticks (Including Tick Paralysis)


SECTION L: DISEASES OF UNKNOWN ETIOLOGY
296. Kawasaki Syndrome

PART IV. Special Problems

SECTION A. NOSOCOMIAL INFECTIONS
304. Human Immunodeficiency Virus in Health Care Settings
305. Nosocomial Herpesvirus Infections

SECTION B. INFECTIONS IN SPECIAL HOSTS
306. Infections in the Immunocompromised Host: General Principles
307. Infections in Patients with Hematologic Malignancies
308. Prophylaxis and Empirical Therapy for Infection in Cancer Patients
309. Infections in Injection Drug Users
310. Risk Factors and Approaches to Infections in Transplant Recipients
311. Infections in Recipients of Hematopoietic Stem Cell Transplantation
312. Infections in Solid Organ Transplant Recipients
313. Infections in Patients with Spinal Cord Injury
314. Infections in the Elderly

315. Infections in Asplenic Patients

SECTION C. SURGICAL- AND TRAUMA-RELATED INFECTIONS

316. Postoperative Infections and Antimicrobial Prophylaxis
317. Burns
318. Bites

SECTION D. IMMUNIZATION
319. Immunization

SECTION E. BIODEFENSE
320. Bioterrorism: An Overview
321. Plague as an Agent of Bioterrorism
322. Francisella tularensis (Tularemia) as an Agent of Bioterrorism
323. Smallpox and Bioterrorism
324. Anthrax
325. Botulinum Toxin as a Biological Weapon
326. Bioterrorism: Viral Hemorrhagic Fevers

SECTION F. ZOONOSES
327. Zoonoses

SECTION G. PROTECTION OF TRAVELERS
328. Protection of Travelers
329. Infections in Returning Travelers

SECTION H. THE INTERNET
330. The Infectious Diseases Physician and Digital Resources

Index, i

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