Plant-Pathogen Interactions: Annual Plant Reviews

Plant-Pathogen Interactions: Annual Plant Reviews, Volume Eleven (ANNUAL PLANT REVIEWS)
by Nick Talbot (Editor)

Product Details
* Hardcover: 248 pages
* Publisher: Blackwell; 1 edition (May 19, 2004)
* Language: English
* ISBN-10: 0849323436

Book Description
Plant diseases are destructive and threaten virtually any crop grown on a commercial scale. They are kept in check by plant breeding strategies that have introgressed disease resistance genes into many important crops, and by the deployment of costly control measures, such as antibiotics and fungicides. However, the capacity for the agents of plant disease - viruses, bacteria, fungi, and oomycetes - to adapt to new conditions, overcoming disease resistance and becoming resistant to pesticides, is very great. For these reasons, understanding the biology of plant diseases is essential for the development of durable control strategies. Plant-Pathogen Interactions provides and overview of our current knowledge of plant-pathogen interactions and the establishment of plant disease, drawing together fundamental new information on plant infection mechanisms and host responses. The role of molecular signals, gene regulation, and the physiology of pathogenic organisms are emphasized, but the role of the prevailing environment in the conditioning of disease is also discussed. Emphasizing the broader understanding that has emerged from the use of molecular genetics and genomics, Plant-Pathogen Interactions highlights those interactions that have been most widely studied and those in which genome information has provided a new level of understanding.

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Virology Methods Manual

Virology Methods Manual, First Edition
by Hillar O. Kangro (Editor)

Product Details
* Plastic Comb: 374 pages
* Publisher: Academic Press; 1st edition (January 15, 1996)
* Language: English
* ISBN-10: 0124653308

Book Description
The Virology Methods Manual is a comprehensive source of methods for the study, manipulation, and detection of viruses. Edited by Brian Mahy and Hillar Kangro, this work describes the most up-to-date, definitive techniques, provided by experts in each area, and presented with easy-to-use, step-by-step protocols. This new manual will satisfy the needs of virologists and all those working with viruses who need a practical guide to methods that work!
Key Features
* Provides up-to-date techniques by experts worldwide
* Presents common, step-by-step protocols in an attractive, easy-to-use fashion
* Contains useful appendices including virus taxonomy, metabolic inhibitors, and Bio-safety in the virology laboratory

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Allergy, Asthma, and Immune Deficiency , An Issue of Primary Care Clinics in Office Practice

Allergy, Asthma, and Immune Deficiency , An Issue of Primary Care Clinics in Office Practice (The Clinics: Internal Medicine)
by Rohit Katial (Author)

Product Details
* Hardcover: 240 pages
* Publisher: Saunders (March 28, 2008)
* Language: English
* ISBN-10: 1416057854

Book Description
This issue is intended aid the physicians understanding of common allergic and immunologic diseases seen in a primary care practice and also to present the latest information about these problems. In addition to asthma, the issue includes discussions of allergic rhinitisone of the most common chronic diseasesand urticaria, food allergy, and acute versus chronic sinusitis.

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Plant Surface Microbiology

Plant Surface Microbiology
by Ajit Varma (Editor), Lynette Abbott (Editor), Dietrich Werner (Editor), Rüdiger Hampp

Product Details
Paperback: 628 pages
Publisher: Springer; 1 edition (December 6, 2007)
Language: English
ISBN-10: 3540740503

Book Description
Most plants rely on the co-existence with microorganisms: both groups benefit from these symbioses. It has been shown that a large number of specific genes in plants and microorganisms are only activated during these interactions. Of course, various microbes also act as pathogens.
Interactions between plants and microorganisms are often located on plant surfaces, such as leaf cuticles, seeds and mainly on the roots. The communication between plants and microbes is the main topic treated in "Plant Surface Microbiology", such as the signaling within a symbiosis, the molecular differences between symbiotic and pathogenic microorganisms, the role of microorganisms in the development of plants or in plant protection against deleterious agents. Further contributions are devoted to: the analysis of bacterial communities in the rhizosphere; microbial population genetics; aspects of mycorrhizal symbiosis; functional genomic approaches and the use of microorganisms as bio-indicator of soil disturbance.

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Psychrophiles: from Biodiversity to Biotechnolgy

Psychrophiles: from Biodiversity to Biotechnolgy
by Rosa Margesin (Editor), Franz Schinner (Editor), Jean-Claude Marx (Editor), Charles Gerday (Editor)

Product Details
Hardcover: 462 pages
Publisher: Springer; 1 edition (December 18, 2007)
Language: English
ISBN-10: 3540743340

Book Description
The majority of the Earth s biosphere is cold and exposed to temperatures below 5°C throughout the year. Having evolved special mechanisms to overcome the life-endangering influence of low temperatures, psychrophiles, i.e. cold-adapted microorganisms, have successfully colonized these environments. Cold adaptation includes a complex range of structural and functional adaptations at the level of all cellular constituents, and these adaptations render cold-adapted organisms particularly useful for biotechnological applications. This book presents the most recent knowledge of (i) boundary conditions for microbial life in the cold, (ii) microbial diversity in various cold ecosystems, (iii) molecular cold adaptation mechanisms and (iv) the resulting biotechnological perspectives.

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Advances in Microbial Physiology, Volume 53

Advances in Microbial Physiology, Volume 53 (Advances in Microbial Physiology) (Advances in Microbial Physiology)
by Robert K. Poole (Series Editor)

Product Details
Hardcover: 300 pages
Publisher: Academic Press; 1 edition (October 15, 2007)
Language: English
ISBN-10: 0123737133

Book Description:
Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work.
First published in 1967, the editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to traditional views of whole cell physiology. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to be an influential and very well reviewed series.

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Functional Genetics of Industrial Yeast

Functional Genetics of Industrial Yeasts (Topics in Current Genetics)
by Johannes H. de Winde (Editor)

Product Details
Hardcover: 367 pages
Publisher: Springer; 1 edition (August 13, 2003)
Language: English
ISBN-10: 3540024891

Book Description
Yeasts have a longstanding history as domesticated organisms. The brewing of beer and wine and the leavening of bread dough are well-known artisanal applications of yeast. These early examples of yeast biotechnology have clearly contributed to the acceptance of yeasts, both as biotechnological workhorses and as model systems for the detailed understanding of eukaryotic molecular cell biology and genetics.
In recent years, new yeast species have proven their value and novel biotechnological applications have emerged. This book compiles the multi-faceted genetic repertoire of several yeasts relevant to modern biotechnology, and describes their utilization in research and application in the light of their genetic make-up and physiological characteristics. Moreover, the book presents a thorough overview of a wide array of methodologies from classical genetics to modern genomics technologies that have been and are being used in functional analysis of yeasts.

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Hepatitis C Virus Disease: Immunobiology and Clinical Applications

Hepatitis C Virus Disease: Immunobiology and Clinical Applications
by Emilio Jirillo (Editor)

Product Details
Hardcover: 308 pages
Publisher: Springer; 1 edition (November 13, 2007)
Language: English
ISBN-10: 0387713751

Book Description
The Hepatitis C Virus is a major global health problem affecting more than 170 million people. HCV can eventually lead to cirrhosis, liver failure, and cancer in many instances. This volume will include comprehensive original papers that cover much of the past, current, and future literature that has appeared since the identification of the hepatitis C virus RNA genome. It will specifically deal with the effects of various types of interferons in basic research and clinical outcomes of HCV disease and its progression. The novelty of this publication will be that the immunobiology of HCV and the IFN-induced modification of the immune response will be emphasized more clearly then it has ever been in any other publication. It will be the immunobiology section that will help readers better understand the clinical efficacy of Interferon treatment. It will be a valuable volume for the student, researcher, or clinician interested in HCV transmission, molecular virology, immune response, cellular/molecular pathogenesis, and possibilities for developing effective new therapeutics and vaccines.

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Molecular Biology of Spirochete

Molecular Biology of Spirochetes (NATO Science Series: Life and Behavioural Sciences, Vol. 373)
by F. C. Cabello (Editor), D. Hulinska (Editor), H. P. Godfrey (Editor)

Product Details
Hardcover: 416 pages
Publisher: IOS Press; 1 edition (October 1, 2006)
Language: English
ISBN-10: 1586036653

Book Description
Diseases produced by spirochetes, including Lyme borreliosis, syphilis and leptospirosis, are on the rise worldwide, and because the biology of their causative organisms, their epidemiology, and clinical presentation display important variations in different geographical areas. For example B. burgdorferi sensu lato produces approximately 20,000 cases of Lyme borreliosis a year in the United States and 60,000 cases in Europe, but B. burgdorferi sensu stricto, B. afzelii and B. garinii are transmitted by different vectors and have different reservoirs and clinical presentations in these different geographic areas. Awareness and better understanding of these variations by researchers in the field is thus highly relevant to improvements in their prevention and treatment, and critical for improvement of human health. This volume focuses on a series of state-of-the-art presentations of the research taking place in the laboratories of the contributors. As such, it may be useful as an introduction to those individuals entering in the burgeoning field of spirochete research. This book could serve as a stimulus for researchers in the field to widen collaborations and exchanges between investigators in the different geographical areas where spirochetal diseases are common since these interactions can only be of benefit to the field.

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Molecular Techniques in the Microbial Ecology of Fermented Foods

Molecular Techniques in the Microbial Ecology of Fermented Foods (Food Microbiology and Food Safety)
by Luca Cocolin (Editor), Danilo Ercolini (Editor)

Product Details
* Hardcover: 284 pages
* Publisher: Springer; 1 edition (November 9, 2007)
* Language: English
* ISBN-10: 038774519X

Book Description
With the application of new analytical techniques, the field of food fermentation has grown over last few years. Because of this, the approach to study bacteria in food has changed. Consequently new information is available on the structure and dynamics of microbial populations during fermented food production.
Molecular Techniques in the Microbial Ecology of Fermented Foods provides the latest information and relevant advances on the microbial ecology of fermented foods and the application of molecular methods. This book serves as a guide for students and researchers on the most advanced techniques to identify bacteria and helps in choosing the most appropriate tools to study fermented food from a microbiological point of view.

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Rifaximin: A Poorly Absorbed Antibiotic

Rifaximin: A Poorly Absorbed Antibiotic
by C. Scarpignato (Editor)

Product Details
* Hardcover: 250 pages
* Publisher: S. Karger AG (Switzerland) (April 30, 2005)
* Language: English
* ISBN-10: 3805579179

Book Description
Rifaximin is a semisynthetic rifamycin which is not absorbed from the gastrointestinal tract. It has been available in Europe and other countries for several years, and has recently been approved for treatment of travelers diarrhea in the United States. Because of its broad spectrum of anti-microbial activity, rifaximin has been used with success in the treatment of infectious diarrhea, hepatic encephalopathy, small intestinal bacterial overgrowth, inflammatory bowel disease, and colonic diverticular disease. Potential indications include the irritable bowel syndrome and chronic constipation, Clostridium difficile infection and bowel preparation before colorectal surgery.
In this publication both the present and future clinical use of rifaximin as well as the pharmacology behind it are extensively reviewed. Compiling the latest information on this remarkably active antibacterial agent, it will be an essential resource for infectiologists, gastroenterologists, and digestive surgeons

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Pocket guide to Antimicrobial Therapy in Otolaryngology

Pocket guide to Antimicrobial Therapy in Otolaryngology - Head and Neck Surgery 13th Edition
by David N. F Fairbanks

This publication is offered as a concise, practical guide to the practicing physician dealing with the usual or average patient. No recommendations for antimicrobial therapy can be absolute, and the good clinician will modify them according to special circumstances in his patient or community. The recommendations contained herein are not to be considered as any official position of the Academy, but, rather, the opinions of the author, the members of the committees, and other consultants at the time of publication; they are subject to change as new developments occur. It is anticipated that this guide will be revised and updated biennially. (It is now in its thirteenth edition with more than 1.25 million copies printed since 1981.)
Brief comment:The 13th edition of the Guide to Antimicrobial Therapy in Otolaryngology—Head and Neck Surgery helps physicians prescribe the most effective, least expensive antimicrobials for their patients, and provides an overview of antimicrobials by category, microbiology, drug selections, prophylaxis, ototoxicity, adverse interactions, drugs of choice according to infecting organism, dosages, and cost.

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Pediatric Allergy, Asthma and Immunology

Pediatric Allergy, Asthma and Immunology
by Arnaldo Cantani (Author)

Product Details:
* Hardcover: 1619 pages
* Publisher: Springer; 1 edition (January 31, 2008)
* Language: English
* ISBN-10: 3540207686

Book Description
Pediatric Allergy, Asthma and Immunology reflects the rapid progress in one of the most intriguing fields of medicine. The book offers state-of-the-art information on basic immunology, fetal-neonatal immunology, genetic and environmental predisposing factors, epidemiology and natural history of atopic diseases, and allergy diagnosis. Extensive coverage is devoted to skin conditions and food allergy, asthma, rhinitis, specific immunotherapy, eye disorders, sinusitis and secretory otitis media, drug allergies, and anaphylaxis. Fascinating chapters explore such topics as autoimmune diseases, primary immunodeficiencies, pediatric HIV infection, malnutrition and the immune system. Finally, a chapter on prevention of the atopic march indicates how effective early intervention may greatly decrease the upsurge in atopy. Easy to understand and easy to use, Pediatric Allergy, Asthma and Immunology is essential reading for medical students, practicing physicians, allergists, immunologists, and researchers.

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Toll-Like Receptors (TLRs) and Innate Immunity

Toll-Like Receptors (TLRs) and Innate Immunity
by Stefan Bauer (Editor), Gunther Hartmann (Editor)

Product Details:
* Hardcover: 240 pages
* Publisher: Springer; 1 edition (January 8, 2008)
* Language: English
* ISBN-10: 3540721665

Book Description
Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.

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The Discovery of the Germ

The Discovery of the Germ (Revolutions in Science)
by John Waller (Author)

Product Details:
* Hardcover: 176 pages
* Publisher: Icon Books Ltd (July 2002)
* Language: English
* ISBN-10: 1840463732

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Cardiology clinics : Issue on infective endocarditis

Cardiology clinics : issue on infective endocarditis

Chapters included :

1) Assessment and management of complications in infective endocarditis
2) Current best practices and guidelines Indications for surgical intervention in infective endocarditis
3) Diagnostic methods Current best practices and guidelines for isolation of bacteria and fungi in infective endocarditis 1
4) Diagnostic methods Current best practices and guidelines for isolation of bacteria and fungi in infective endocarditis 2
5) Imaging techniques for diagnosis of infective endocarditis
6) Infections of intracardiac devices
7) Infective endocarditis and cardiac surgery in intravenous drug abusers and HIV-1 infected patients
8) Infective endocarditis
9) internatioanl coll on IE
10) Staphylococcus aureus bacteremia and endocarditis

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Toxoplasma Gondii: The Model Apicomplexan. Perspectives and Methods

Toxoplasma Gondii: The Model Apicomplexan. Perspectives and Methods
by Louis M Weiss (Editor), Kami Kim (Editor)

Product Details
Hardcover: 800 pages
Publisher: Academic Press; 1 edition (April 10, 2007)
Language: English
ISBN-10: 0123695422

Book Description
Toxoplasmosis is caused by a one-celled protozoan parasite known as Toxoplasma gondii. In the United States, it is estimated that approximately 30% of cats, the primary carriers, have been infected by T. gondii. Most humans contract toxoplasmosis by eating cyst-contaminated raw or undercooked meat, vegetables, or milk products or when they come into contact with the T. gondii eggs from cat feaces while cleaning a cat's litterbox, gardening, or playing in a sandbox. Approx 1 in 4 (more than 60 million) people in the USA are infected with the parasite, and in the UK between 0.5 and 1% of individuals become infected each year. By the age of 50, 40% of people test positive for the parasite. The predilection of this parasite is for the central nervous system (CNS) causing behavioral and personality alterations as well as fatal necrotizing encephalitis, and is especially dangerous for HIV infected patients.
Though there have been tremendous strides in our understanding of the biology of Toxoplasma gondii in the last decade, there has been no systemic review of all of the information that has accumulated. Toxoplasma gondii provides the first comprehensive summary of literature on this organism by leading experts in the field who were responsible for organising the 7th International Congress on Toxoplasmosis in May 2003. It offeres systematic reviews of the biology of this pathogen as well as descriptions of the methods and resources used. Within the next year the T. gondii genome will be completed making this an indispensable research resource for biologists, physicians, parasitologists, and for all those contemplating experiments using T. gondii.

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Food spoilage microorganisms

Food spoilage microorganisms
by Clive de W. Blackburn (Editor)

Product Details
Hardcover: 712 pages
Publisher: CRC; 1 edition (March 31, 2006)
Language: English
ISBN-10: 0849391563

Book Description
The control of microbiological spoilage requires an understanding of a number of factors including the knowledge of possible hazards, their likely occurrence in different products, their physiological properties, and the availability and effectiveness of different preventative measures. Food Spoilage Microorganisms focuses on the control of microbial spoilage and provides an understanding necessary to do this. The first part of this essential new book looks at tools, techniques, and methods for the detection and analysis of microbial food spoilage with chapters focusing on analytical methods, predictive modeling, and stability and shelf life assessment. The second part tackles the management of microbial food spoilage with particular reference to some of the major food groups where the types of spoilage, the causative microorganisms, and methods for control are considered by product type. The following three parts are then dedicated to yeasts, molds, and bacteria in turn, and look in more detail at the major organisms of significance for food spoilage. In each chapter the taxonomy, spoilage characteristics, growth, survival, and death characteristics, methods for detection, and control options are discussed. Food Spoilage Microorganisms takes an applied approach to the subject and will be an indispensable guide both for the microbiologist and the non-specialist, particularly those whose role involves microbial quality in food processing operations.

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Breeding for Disease Resistance in Farm Animals

Breeding for Disease Resistance in Farm Animals
by R. F. E. Axford (Editor), S. C. Bishop (Editor), F. W. Nicholas (Editor), J. B. Owen (Editor)

Product Details
Hardcover: 550 pages
Publisher: CABI; 2 Sub edition (February 7, 2000)
Language: English
ISBN-10: 0851993257

Book Description
This second edition has been thoroughly updated with additional editors, authors and is no longer based on a symposium and so includes a broader range of topics. This book covers all aspects of the genetic control of disease resistance in farm animals and the utilisation of this information to breed animals with enhanced disease resistance. It includes both metabolic and infectious diseases, including those caused or borne by viruses, bacteria, helminths, ticks and flies, in both intensive and extensive, and also tropical and temperate production systems. This provides a sound base for the understanding of many infectious and metabolic diseases of economic importance throughout the world in all major domestic species, understanding the current knowledge of the gentic control of these diseases, and appreciation of the scope for genetic solutions to these disease problems and a knowledge of the tools available to achieve those solutions.

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Living with Germs: In Sickness and in Health

Living with Germs: In Sickness and in Health
by John Playfair (Author)

Product Details
Paperback: 272 pages
Publisher: Oxford University Press, USA; 1 edition (April 27, 2007)
Language: English
ISBN-10: 0192805827

Book Description
The word germ is defined as 'a microbe that causes disease'. The vast majority of microbes do not infect us at all: it is pathogens that make us ill. These include bacteria, viruses, protozoa, fungi, worms, and prions. Living with Germs not only looks at all of these in detail, but also at the defence mechanisms by which we come to terms with them, whether by eliminating them, stopping them from eliminating us, or simply learning to live with them. This is the first book to look at the subject of immunology in a relevant and approachable style. Using anecdotal and autobiographical material, John Playfair has produced a lively, well-written, and up-to-date look at immunology. Timely and topical, this will appeal to all those who want to know the facts behind the 'germ' scare stories.

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The Year in Infection, Volume 2

The Year in Infection, Volume 2 (Year in Infection)
by M. Wilcox (Editor)

Product Details
Hardcover: 301 pages
Publisher: Informa Healthcare (March 8, 2005)
Language: English
ISBN-10: 1904392326

Book Description
Throughout the 20th century infectious diseases remained the leading cause of premature mortality, but increasing availability of drugs and vaccines to combat and prevent infection led many to believe that the threat from infectious disease in industrialized countries was all but over. However recent events have proved that this is not the case. The Year in Infection 2004 is a concise guide to infectious diseases bringing together information about all aspects of infectious diseases into one accessible volume. Compiled by a leading team of experts, this volume will prove an invaluable resource for all those involved in the treatment of infectious diseases.

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Viral Hepatitis

Viral Hepatitis
by Howard C. Thomas (Editor), Stanley Lemon (Editor), Arie J. Zuckerman (Editor)

Product Details
Hardcover: 896 pages
Publisher: Wiley-Blackwell; 3 edition (July 29, 2005)
Language: English
ISBN-10: 1405130059

Book Description
Does viral hepatitis merit a 649-page, 10-lb review? It certainly does. Readers and the publisher appear to agree, because Viral Hepatitis has now appeared in a second edition. Hepatitis viruses are important agents of disease worldwide, and hepatitis B virus (HBV) and hepatitis C virus (HCV), which produce chronic infections, affect hundreds of millions of people. These two viruses cause most cases of chronic hepatitis, cirrhosis, and liver cancer in the world.
Viral Hepatitis, a multiauthored work, aims to present to clinicians, pathologists, and epidemiologists the best of our understanding of the basic virology of the hepatitis viruses and of some viruses, such as hepatitis G virus, that resemble but do not seem actually to be hepatitis viruses. Virologists will benefit from reviews of the current understanding of clinical and epidemiologic aspects of hepatitis viruses.
The introduction to the book was written by Dame Sheila Sherlock, the doyenne of the field, and is a superb review of the clinical features of hepatitis. The book is organized into sections on each of the viruses, with chapters on molecular virology, epidemiology, natural history, diagnosis, pathogenesis, treatment, and prevention. These chapters, which review comprehensively what is known about these viruses, are followed by more general reviews on, for example, the treatment of fulminant hepatitis, transfusion-associated hepatitis, and the application of molecular biology to the diagnosis of viral hepatitis. The latter chapter, by Brechot, is superb, supplementing and clarifying material covered in previous chapters.
Virologists will be particularly interested in chapters such as Kann and Gerlich's elegantly illustrated and imaginative review of the molecular virology of HBV and the comprehensive review of the molecular virology of HCV by McGarvey et al. No better reviews of these subjects are available. The review by Buendia et al. of the molecular aspects of hepatocelluar carcinoma, which is thought by some to be the world's most common cancer, at least in men, is especially noteworthy; it reveals the little-appreciated fact that half of the patients with hepatocellular carcinoma who test negative for hepatitis B surface antigens have HBV DNA sequences in their tumors. Other chapters that are especially interesting are Thomas and Thursz's review of the pathogenesis of chronic HBV infections and Okuda's review of the natural history of chronic hepatitis C and hepatocellular carcinoma.
All in all, reading this book will be a stimulating educational experience for virologists, clinicians, epidemiologists, and pathologists who are interested in liver disease. Viral Hepatitis deserves to be in many home libraries; a paperback edition, with a lower price, would be welcome. The rate of progress in this field is such that the third edition should not be long in coming.

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Allergy and Asthma: Practical Diagnosis and Management

Allergy and Asthma: Practical Diagnosis and Management (Lange Medical Books)
by Massoud Mahmoudi (Author)

Product Details
Paperback: 400 pages
Publisher: McGraw-Hill Professional; 1 edition (September 18, 2007)
Language: English
ISBN-10: 0071471731

Book Description
Clear, authoritative guidance for your day-to-day allergy and asthma practice
Allergy and Asthma: Practical Diagnosis and Management is a concise guide that puts the most salient insights in allergy medicine right at your fingertips. Written by a leading allergy clinician, along with 30 nationally recognized expert contributors, this resource is perfect for front-line general practitioners, especially primary care physicians and allied health care providers. Inside, you'll find the most clinically relevant information on the pathophysiology, diagnosis, treatment, and prevention of all major allergic disorders.
Features
Need-to-know coverage that spans the entire scope of adult allergy and asthma-geared for real world medical practice
A timely look at occupational allergies and allergies linked to unhealthy environments
Organization by specific organ, which guides you to diagnostic and therapeutic solutions quickly and easily
Essential chapters on the principles of diagnosis and on medications used in the management of simple and complex allergy
Coverage of new complementary and alternative medicine techniques in the management of allergic disorders
Over 100 outstanding illustrations
Key concepts, management protocols, and recent references that deliver s a highly accessible overview of today's allergy practice

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Diagnosis and Treatment of Human Mycoses

Diagnosis and Treatment of Human Mycoses (Infectious Disease)
by Duane R. Hospenthal (Editor), Michael G. Rinaldi (Editor)

Product Details
Hardcover: 448 pages
Publisher: Humana Press; 1 edition (November 29, 2007)
Language: English
ISBN-10: 1588298221

Book Description
Diagnosis and Treatment of Human Mycoses brings together globally-recognized mycoses experts to guide readers in the use of current knowledge in the field of medical mycology to manage those who suffer from fungal infections (mycoses). Often, diagnostic strategies and tests, including basic and directed culturing techniques, histopathology with standard and special stains, serological methods, and radiological studies all need to be considered and commonly combined to make the diagnosis of fungal infection. This volume first introduces and reviews these tools separately and then as they pertain to specific infections or groups of diseases. The volume consists of four parts. Parts I-III provide an overview of diagnostic and therapeutic tools, and part IV presents the human mycoses.
Diagnosis and Treatment of Human Mycoses is meant to be a concise text that will provide the busy infectious disease, hematologyoncology, pulmonology, or critical care specialist a practical tool to diagnose and manage fungal infections. In addition, the depth of the material in the text will provide these and other medical specialists and trainees an excellent reference and learning resource.

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Pathogenic Mycobacteria in Water: A Guide to Public Health Consequences, Monitoring and Management

Pathogenic Mycobacteria in Water: A Guide to Public Health Consequences, Monitoring and Management (Who Emerging Issues in Water & Infectious Disease)
by S. Pedley (Editor), J. Bartram (Editor), G. Rees (Editor), A. Dufour (Editor), J. Cotruvo (Editor)

Product Details
Hardcover: 250 pages
Publisher: IWA Publishing (Intl Water Assoc); Cdr edition (August 30, 2004)
Language: English
ISBN-10: 1843390590

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Seasonal Patterns of Stress, Immune Function, and Disease

Seasonal Patterns of Stress, Immune Function, and Disease
by Randy J. Nelson (Author), Gregory E. Demas (Author), Sabra L. Klein (Author), Lance J. Kriegsfeld (Author)

Product Details
Hardcover: 308 pages
Publisher: Cambridge University Press; 1 edition (March 25, 2002)
Language: English
ISBN-10: 052159068

Book Description
This volume presents evidence that infection is cyclical with the seasons, and that this phenomenon is mirrored in cycles of immune function. The authors identify the mechanisms by which immune systems are bolstered to counteract seasonally-recurrent stressors, such as extreme temperature reductions and food shortages. Stress, infectious diseases, autoimmune diseases, and human cancers are examined, and the role of hormones such as melatonin and glucocorticoids are considered. This is the first monograph to examine seasonal immune function from an interdisciplinary perspective.

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Catheter-Related Infections In The Critically IIl

Catheter-Related Infections In The Critically III (Perspectives on Critical Care Infectious Diseases)
by Naomi P. O'Grady (Editor), Didier Pittet (Editor)

Product Details
Hardcover: 172 pages
Publisher: Springer; 1 edition (July 14, 2004)
Language: English
ISBN-10: 1402080093

Book Description
Catheter-Related Infections in the Critically Ill provides an overview from an international perspective on intravascular catheters and the risk of infection. This volume highlights:
Epidemiology
Diagnosis
Impact of Infection
Management and Treatment
Prevention - including Education as the Primary Tool for Prevention
The purpose of this book is to provide the practitioner with the most interesting and useful data in the field of catheter-related infection. It is hoped that the strategies to prevent infection detailed by the authors will be implemented and have a measurable impact in decreasing rates of infection in the intensive care unit setting.

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Phoma Identification Manual: Differentiation of Specific and Infra-specific Taxa in Culture

Phoma Identification Manual: Differentiation of Specific and Infra-specific Taxa in Culture
by G. H. Boerema (Author), J. de Gruyer (Author), M. E. Noordeloos (Author), Maria E. C. Hamers (Author)

Product Details
Hardcover: 480 pages
Publisher: CABI; 1 edition (September 10, 2004)
Language: English
ISBN-10: 0851997430

Book Description
Phoma is a genus of fungi within the Coelomycetes. These fungi are commonly and frequently recovered in culture from all ecological situations, but are very difficult to identify. There has been a great need for a practical manual to aid such identification, and this book will fill that gap. It provides line drawings and keys for the identification of common pathogenic and saprotrophic species of Phoma in vitro, with references to additional diagnostic literature and documentation of the numerous synonyms formerly used in the phytopathological literature.

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Infections and the Cardiovascular System: New Perspectives

Infections and the Cardiovascular System: New Perspectives (Emerging Infectious Diseases of the 21st Century)
by I.W. Fong (Author)

Product Details
Hardcover: 256 pages
Publisher: Springer; 1 edition (February 28, 2003)
Language: English
ISBN-10: 0306474042

Book Description
Infectious agents have been recognized to involve the heart and vascular system for well over a century. Traditional concepts and teachings of their involvement in the pathogenesis of disease have been by a few established mechanisms. Since the last decade of the 20th century there has been renewed interest in the medical and public media on infectious diseases affecting the cardiovascular and cerebrovascular systems, through their relationship with the development of acceleration of atherosclerosis. This volume highlights and reviews new perspectives of infections on the cardiovascular system as never before. It is a truly valuable resource for scientists, researchers, residents, and fellows in the fields of infectious disease, cardiology, and microbiology.

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Disease and Democracy: The Industrialized World Faces AIDS

Disease and Democracy: The Industrialized World Faces AIDS (California/Milbank Books on Health and the Public)
by Peter Baldwin (Author)

Product Details
Hardcover: 478 pages
Publisher: University of California Press; 1 edition (May 16, 2005)
Language: English
ISBN-10: 052024350

Book Description
Disease and Democracy is the first comparative analysis of how Western democratic nations have coped with AIDS. Peter Baldwin's exploration of divergent approaches to the epidemic in the United States and several European nations is a springboard for a wide-ranging and sophisticated historical analysis of public health practices and policies. In addition to his comprehensive presentation of information on approaches to AIDS, Baldwin's authoritative book provides a new perspective on our most enduring political dilemma: how to reconcile individual liberty with the safety of the community.
Baldwin finds that Western democratic nations have adopted much more varied approaches to AIDS than is commonly recognized. He situates the range of responses to AIDS within the span of past attempts to control contagious disease and discovers the crucial role that history has played in developing these various approaches. Baldwin finds that the various tactics adopted to fight AIDS have sprung largely from those adopted against the classic epidemic diseases of the nineteenth century--especially cholera--and that they reflect the long institutional memories embodied in public health institutions.

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What's Wrong With My Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice

What's Wrong With My Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice
by Jacqueline N., PhD Crawley (Author)

Product Details
* Hardcover: 523 pages
* Publisher: Wiley-Liss; 2 edition (March 23, 2007)
* Language: English
* ISBN-10: 0471471925

Book Description
Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse?
Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters:
"Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis.
"Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions.
The final chapter, "The Next Generation," examines new and emerging technologies.
Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.

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Biologic Markers in Immunotoxicology

Biologic Markers in Immunotoxicology
by Subcommittee on Immunotoxicology, Committee on Biologic Markers, Board on Environmental Studies and

The Committee on Biologic Markers was organized to consider the areas of environmental research in which the use of biologic markers offered the greatest potential for major contributions. Four biologic systems were chosen: the reproductive system, the respiratory system, the immune system, and the urinary system. A companion report, report is the product of the Subcommittee on Immunotoxicology, which included clinicians, epidemiologists,
toxicologists, pathologists, and biochemists. Our intent was to consider various kinds of basic research that might reveal markers of environmental exposure and disease, even if the original goal of the research had nothing to do with such markers. Eventually, the subcommittee decided to place major emphasis on biologic markers of three types: markers originating from the immune system, markers related to immunosuppressive toxicants of exposure, and markers of effects of environmental pollutants. Markers of susceptibility to
environmental materials also were considered important and were included especially if they were of a genetic nature and could serve to identify individuals who are susceptible to autoimmune diseases.

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The Diatoms

The Diatoms
by E. F. Stoermer (Editor), John P. Smol (Editor)

Product Details
* Paperback: 482 pages
* Publisher: Cambridge University Press; 1st edition (August 15, 2001)
* Language: English
* ISBN-10: 0521004128

Book Description
Diatoms are microscopic algae which are found in virtually every habitat where water is present. This volume is an up-to-date summary of the expanding field of their uses in environmental and earth sciences. Their abundance and wide distribution, and their well-preserved glass-like walls make them ideal tools for a wide range of applications as both fossils and living organisms. Examples of their wide range of applications include environmental indicators, oil exploration, and forensic examination. The major emphasis is on their use in analyzing ecological problems such as climate change, acidification, and eutrophication. The contributors to the volume are leading researchers in their fields and are brought together for the first time to give a timely synopsis of a dynamic and important area. This book should be read by environmental scientists, phycologists, limnologists, ecologists and palaeoecologists, oceanographers, archaeologists and forensic scientists.

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Insect Immunology

Insect Immunology
by Nancy E. Beckage (Editor)

Product Details
* Hardcover: 384 pages
* Publisher: Academic Press; 1 edition (December 14, 2007)
* Language: English
* ISBN-10: 0123739764

Book Description
Given the critical importance of insect immunology in insect vector-parasite interactions and vector control, biological control of agricultural insect pests, and other key areas of entomological research and practice, a new comprehensive work summarizing recent breakthroughs in this rapidly expanding field is sorely needed. This work will constitute the first book-length publication on the topic of insect immunology since 1991, complimenting earlier works by offering a fresh perspective on current research. Interactions of host immune systems with both parasites and pathogens will be presented as well as the genomics and proteomics approaches which have been lacking in other publication.

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Phagocytosis of Bacteria and Bacterial Pathogenicity

Phagocytosis of Bacteria and Bacterial Pathogenicity (Advances in Molecular and Cellular Microbiology)
by Joel D. Ernst (Editor), Olle Stendahl (Editor)

Product Details
* Hardcover: 296 pages
* Publisher: Cambridge University Press; 1 edition (September 25, 2006)
* Language: English
* ISBN-10: 0521845696

Book Description
This book provides up-to-date information on the crucial interaction of pathogenic bacteria and professional phagocytes, the host cells whose purpose is to ingest, kill, and digest bacteria in defense against infection. The introductory chapters focus on the receptors used by professional phagocytes to recognize and phagocytose bacteria, and the signal transduction events that are essential for phagocytosis of bacteria. Subsequent chapters discuss specific bacterial pathogens and the strategies they use in confronting professional phagocytes. Examples include Helicobacter pylori, Streptococcus pneumoniae, and Yersinae, each of which uses distinct mechanisms to avoid being phagocytosed and killed. Contrasting examples include Listeria monocytogenes and Mycobacterium tuberculosis, which survive and replicate intracellularly, and actually cooperate with phagocytes to promote their entry into these cells. Together, the contributions in this book provide an outstanding review of current knowledge regarding the mechanisms of phagocytosis and how specific pathogenic bacteria avoid or exploit these mechanisms.

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The Primate Malarias

The Primate Malarias
by U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE

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Handbook of Laboratory Animal Management and Welfare

Handbook of Laboratory Animal Management and Welfare
by Sarah Wolfensohn (Author), Maggie Lloyd (Author)

Product Details
* Paperback: 432 pages
* Publisher: Wiley-Blackwell; 3 edition (October 3, 2003)
* Language: English
* ISBN-10: 1405111593

Book Description
This third edition of the bestseller Handbook of Laboratory Animal Management & Welfare has been fully revised and updated making it an essential handbook for all those working with animals under the Animals (Scientific Procedures) Act, 1986. Designed to be a practical reference book, it covers every area of animal care and aims to improve animal welfare through best practice and refinement of techniques. It covers principles applicable to all species, including training of licensees, the regulatory framework, euthanasia, management of pain and stress, anaesthesia and surgery, and also includes specific sections on biology and husbandry.

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AIDS, Drugs and Society

AIDS, Drugs and Society (Sourcebook on Contemporary Controversies)
by Anna Alexandrova (Editor)

Product Details
* Paperback: 300 pages
* Publisher: International Debate Education Association; Revised edition (November 2004)
* Language: English
* ISBN-10: 0972054189

Book Description
AIDS, Drugs and Society, revised edition, brings together materials that address the interconnected epidemics of HIV/AIDS and drug abuse. Articles focus on the policy and human rights aspects of the issue, in particular, the importance of harm reduction policies in the context of human rights. Some of the texts offer important background information while others present examples of harm reduction initiatives. The book also contains source documents and a glossary of key terms.

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AIDS, Drugs and Society

AIDS, Drugs and Society (Sourcebook on Contemporary Controversies)
by Anna Alexandrova (Editor)

Product Details
* Paperback: 300 pages
* Publisher: International Debate Education Association; Revised edition (November 2004)
* Language: English
* ISBN-10: 0972054189

Book Description
AIDS, Drugs and Society, revised edition, brings together materials that address the interconnected epidemics of HIV/AIDS and drug abuse. Articles focus on the policy and human rights aspects of the issue, in particular, the importance of harm reduction policies in the context of human rights. Some of the texts offer important background information while others present examples of harm reduction initiatives. The book also contains source documents and a glossary of key terms.

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Immunology of Pregnancy

Immunology of Pregnancy (Medical Intelligence Unit)
by Gil Mor (Editor)

Product Details
* Hardcover: 339 pages
* Publisher: Springer; 1 edition (April 1, 2006)
* Language: English
* ISBN-10: 0387306129

Book Description
Reproductive Immunology is a growing area in both immunology and reproductive sciences and is helping us to better understand several complications of pregnancy. Immunology of Pregnancy is the first book to give a complete and up to date review of our knowledge related to the role of the immune system during pregnancy and the interactions between the placenta and the maternal immune system. This new title covers in detail all the different hypotheses and studies related to the immunology of implantation and provide a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR.

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Handbook of Bacterial Adhesion: Principles, Methods, and Applications

Handbook of Bacterial Adhesion: Principles, Methods, and Applications
by Yuehuei H. An (Editor), Richard J. Friedman (Editor)

Product Details:
* Hardcover: 644 pages
* Publisher: Humana Press; 1st edition (February 15, 2000)
* Language: English
* ISBN-10: 0896037940

Book Description
Yuehuei An, MD, and Richard Friedman, MD, FRCSC, assemble the first comprehensive treatment of bacterial adhesion, with major concentration on the powerful experimental methods for its study in biomaterials and tissue. Written by acknowledged experts in the field, these detailed techniques facilitate the study of implant infections in a wide range of devices, including orthopedic prostheses, cardiovascular devices, cerebrospinal fluid shunts and extradural catheters, urological catheters and stents, oral and maxillofacial implants, and even contact lenses. Methods for the study of microbial adhesion to such tissues as respiratory and intestinal mucosa, the urinary tract, and teeth are also included. Comprehensive and highly practical, the Handbook of Bacterial Adhesion: Principles, Methods, and Applications offers biomedical scientists and bioengineering researchers an all-in-one experimental guide to today's best techniques for understanding the nature, mechanisms, and prevention of bacterial adhesion.

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Thermophiles: Biology and Technology at High Temperatures

Thermophiles: Biology and Technology at High Temperatures
by Frank Robb (Editor), Garabed Antranikian (Editor), Dennis Grogan (Editor), Arnold Driessen (Editor)

Product Details
* Hardcover: 368 pages
* Publisher: CRC (December 13, 2007)
* Language: English
* ISBN-10: 0849392144

Book Description
This text reviews recent literature in the thermophile field written by international experts. Much is being learned from thermophiles, especially about biology at the molecular level and the genetic mechanisms that permit adaptation and survival. This book discusses protective strategies based on the resiliency of thermophiles. It also investigates molecular regulatory mechanisms, and protein synthesis. By studying this extreme example, its exaggerated response mechanisms, and its development over many short-lived generations, we can learn about diseases linked to improper protein folding, and also more fully understand the ingenious design of DNA, and all that such an understanding implies regarding survival in a changing environment.

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Adenovirus Methods and Protocols: Volume 2

Adenovirus Methods and Protocols: Volume 2: Ad Proteins and RNA, Lifecycle and Host Interactions, and Phyologenetics (Methods in Molecular Medicine)
by William S.M. Wold (Editor), Ann E. Tollefson (Editor)

Product Details
* Hardcover: 362 pages
* Publisher: Humana Press; 2nd ed. edition (February 26, 2007)
* Language: English
* ISBN-10: 1588299015

Book Description
Adenovirus Methods and Protocols, Second Edition, now in two volumes, is an essential resource for adenovirus (Ad) researchers beginning in the field, and an inspirational starting point for researchers looking to branch into new areas of Ad study. In addition to updating and expanding important chapters from the first edition, the authors have added new chapters that address innovative, exciting areas of emphasis in Ad research, including Ad vector construction and use, real-time PCR, use of new animal models, and methods for quantification of Ad virus or virus expression/interactions. Each of the protocols presented in these volumes is written by trendsetting researchers in their respective areas of expertise.

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The Molecular Biology of Cyanobacteri

The Molecular Biology of Cyanobacteria (Advances in Photosynthesis and Respiration)
by D.A. Bryant (Editor)

Product Details
Hardcover: 916 pages
Publisher: Springer; 1 edition (March 30, 2007)
Language: English
ISBN-10: 0792332229

Book description
The editor has done his job in an excellent way, because the chapters are well-coordinated avoiding copious information, and contain harmonised terminology. The book contains excellent colour plates of crystallised proteins .... The technical quality of the book is perfect. The text has been fluently written ... the book can be highly recommended for scientists and for PhD-students of botany and biochemistry. It would be desirable to have it in libraries or in the book stock of laboratories working in the field of molecular biology and/or photosynthesis or plant phsyiology.'

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Opportunistic Intracellular Bacteria and Immunity

Opportunistic Intracellular Bacteria and Immunity (Infectious Agents and Pathogenesis)
by Lois J. Paradise (Editor), Herman Friedman (Editor), Mauro Bendin

Product Details
Hardcover: 328 pages
Publisher: Springer; 1 edition (January 31, 1999)
Language: English
ISBN-10: 0306458942

Book Description
Opportunistic, intracellular bacterial infections are in the forefront of research today because of the challenges they present to the immunocompromised patient. In this volume, the pathogenesis and immune reaction of these intracellular infections is featured, as are the most typical problems related to antimicrobial chemotherapy, and current approaches to their solution. Notable chapters set the pace for research on the pathogenic and immune reactions to such infections as Mycobacterium tuberculosis Legionella pneumophila Chlamydia trachomatis and Brucella.

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Nature Reviews Immunology - Jan 2008

Nature Reviews Immunology Jan 2008

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New Vaccine Development: Establishing Priorities: Volume II, Diseases of Importance in Developing Countries

New Vaccine Development: Establishing Priorities: Volume II, Diseases of Importance in Developing Countries
by Division of Health Promotion and Disease Prevention (Author), Division of International Health (Author)

Product Details
Paperback: 432 pages
Publisher: National Academies Press (January 1, 1986)
Language: English
ISBN-10: 0309036798

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Agrobacterium

Agrobacterium
by Tzvi Tzfira (Editor), Vitaly Citovsky (Editor)

Product Details
Hardcover: 504 pages
Publisher: Springer; 1 edition (January 25, 2008)
Language: English
ISBN-10: 0387722890

Book Description
Agrobacterium is a plant pathogen which causes the "crown-gall" disease, a neoplastic growth that results from the transfer of a well-defined DNA segment ("transferred DNA", or "T-DNA") from the bacterial Ti (tumor-inducing) plasmid to the host cell, its integration into the host genome, and the expression of oncogenes contained on the T-DNA. The molecular machinery, needed for T-DNA generation and transport into the host cell and encoded by a series of chromosomal (chv) and Ti-plasmid virulence (vir) genes, has been the subject of numerous studies over the past several decades. Today, Agrobacterium is the tool of choice for plant genetic engineering with an ever expanding host range that includes many commercially important crops, flowers, and tree species. Furthermore, its recent application for the genetic transformation of non-plant species, from yeast to cultivated mushrooms and even to human cells, promises this bacterium a unique place in the future of biotechnological applications

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Rheumatic Diseases: Immunological Mechanisms and Prospects for New Therapies

Rheumatic Diseases: Immunological Mechanisms and Prospects for New Therapies
by J. S. H. Gaston (Editor)

Product Details
Hardcover: 288 pages
Publisher: Cambridge University Press; 1 edition (August 15, 1999)
Language: English
ISBN-10: 0521593271

Book Description
This authoritative volume provides a wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases. Advances in our understanding of the immunopathology of diseases such as rheumatoid arthritis, ankylosing spondylitis and SLE, are paving the way for the development of effective and rational new therapies. This exciting prospect is an important influence for ground-breaking research into these diseases and the investigation of new therapeutic options. As the first book to focus exclusively on this burgeoning area of clinical research, this is an invaluable and current resource for all rheumatologists, clinical immunologists, and those seeking to develop effective new therapies to combat rheumatic diseases.

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DNA Microarrays and Gene Expression: From Experiments to Data Analysis and Modeling

DNA Microarrays and Gene Expression: From Experiments to Data Analysis and Modeling
by Pierre Baldi (Author), G. Wesley Hatfield (Author), Wesley G. Hatfield (Author)

Product Details
Hardcover: 230 pages
Publisher: Cambridge University Press; 1 edition (September 30, 2002)
Language: English
ISBN-10: 0521800226

Book Description
Massive data acquisition technologies--such as genome sequencing, high-throughput drug screening, and DNA arrays--are in the process of revolutionizing biology and medicine. This concise, user-friendly and interdisciplinary guide to DNA microarray technology is an introduction and a reference for both biologists and computational scientists. The authors describe the underlying technologies and offer an awareness of the "noise" and pitfalls present in the data generated. They also provide an idea of the different data mining techniques and algorithms that are available to interpret data, and the advantages and disadvantages of each in differing situations.

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Pichia Protocols

Pichia Protocols (Methods in Molecular Biology)
by James M. Cregg (Editor)

Product Details
Hardcover: 268 pages
Publisher: Humana Press; 2nd ed. edition (August 8, 2007)
Language: English
ISBN-10: 1588294293

Book Description
Pichia Protocols focuses on recent developments of Pichia pastoris as a recombinant protein production system. Highlighted topics include a discussion on the use of fermentors to grow Pichia pastoris, information on the O- and N-linked glycosylation, methods for labeling Pichia pastoris expressed proteins for structural studies, and the introduction of mutations in Pichia pastoris genes by the methods of restriction enzyme-mediated integration (REMI).
This volume fully updates and expands upon the first edition of Pichia Protocols, and focuses primarily on information that has come to light since its original publication. Each chapter presents cutting-edge and cornerstone protocols for utilizing P. pastoris as a model recomibinant protein production system.

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Baculovirus and Insect Cell Expression Protocols

Baculovirus and Insect Cell Expression Protocols (Methods in Molecular Biology)
by David W. Murhammer (Editor)

Product Details
Hardcover: 484 pages
Publisher: Humana Press; 2nd ed. edition (July 6, 2007)
Language: English
ISBN-10: 1588295370

Book Description
Baculovirus Expression Protocols is a detailed guide for using the baculovirus expression vector system (BEVS) and/or insect cells to produce recombinant proteins. Procedures for the development and production of baculovirus insecticides at both laboratory and large scale are described in the kind of step-by-step format that the Methods in Molecular Biology series helped standardize. This book is a one-stop source for information on baculoviruses, and includes sections on using modified baculoviruses to express genes in mammalian cells, using Drosophila cell lines, isolating new cell lines, and developing serum-free medium. Specific applications, including using baculovirus and insect cell system to study apoptosis, are also discussed. This updated and expanded edition of Baculovirus Expression Protocols provides a perfect lab manual for biochemists, molecular biologists, biochemical engineers, and others for using the BEVS or insect cell lines to produce recombinant proteins.

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Innate Immunity (Methods in Molecular Biology)

Innate Immunity (Methods in Molecular Biology)
by Jonathan Ewbank (Editor), Eric Vivier (Editor)

Product Details
* Hardcover: 300 pages
* Publisher: Humana Press; 1 edition (November 19, 2007)
* Language: English
* ISBN-10: 1588297462

Book Description
Immunologists today are interested in all of the diverse cell-types involved in host defense and have a deeper appreciation of the importance of innate immune mechanisms as a first line of protection against pathogens. Innate Immunity therefore contains chapters dealing with the isolation and functional characterization of cells involved in innate immunity in mouse and man, including mast cells and eosinophils, and with several chapters focusing on natural killer cells. Other chapters describe methods in statistics, in vivo imaging, genome engineering, mutagenesis and culture that are particularly adapted to the study of innate immunity in these hosts. These approaches and models are being used to dissect the complex interplay between hosts and pathogens, and contribute to developing strategies to help fight infection. With chapters written by experts on the cutting-edge of this technology, Innate Immunity is an essential reference for immunologists, histologists, geneticists, and molecular biologists.

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Actin-Binding Proteins and Disease

Actin-Binding Proteins and Disease (Protein Reviews)
By Cris dos Remedios, Deepak Chhabra

Product Details:
* Publisher: Springer
* Number Of Pages: 348
* Publication Date: 2007-11-26
* ISBN-10 / ASIN: 0387717471
* Binding: Hardcover

Book Description:
This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.

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The Heart in Systemic Autoimmune Diseases, Volume 1

The Heart in Systemic Autoimmune Diseases, Volume 1 (Handbook of Systemic Autoimmune Diseases)
by Andrea Doria (Editor), Paolo Pauletto (Editor), Ronald Asherson (Series Editor)

Product Details:
* Hardcover: 276 pages
* Publisher: Elsevier Science; 1 edition (January 20, 2004)
* Language: English
* ISBN-10: 0444513981

Book Description
This first volume represents the state-of-the-art in the field of cardiovascular disease and autoimmune rheumatic diseases. Systemic autoimmune diseases comprise a family of conditions that share common pathogenetic mechanisms as well as a multi-organ involvement including the heart. This volume has been subdivided into three parts. In the first part, the immune mechanisms involved in cardiac damage have been considered. The role of proinflammatory and regulatory cytokines in driving an autoimmune response to cardiac self-tissues has been analysed. Moreover, the prevalence, the clinical meaning and the hypothetical pathogenicity of a broad spectrum of organ and non-organ specific autoantibodies have been discussed in detail. In the second part of the volume, the role of humoral and innate immunity in promoting the development of atherosclerotic plaque has been extensively reviewed, along with the newly discovered anti-inflammatory properties of statins. These two parts of the volume deal with exciting aspects of this topic, suggesting a very close connection between heart diseases and immunology. Finally, in the third part, the cardiac manifestations observed in the major systemic autoimmune conditions have been comprehensively examined.

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The Neurologic Involvement in Systemic Autoimmune Diseases, Volume 3

The Neurologic Involvement in Systemic Autoimmune Diseases, Volume 3 (Handbook of Systemic Autoimmune Diseases)
by Doruk Erkan (Editor), Steven R. Levine (Editor), Ronald Asherson (Series Editor)

Product Details:
* Hardcover: 296 pages
* Publisher: Elsevier Science; 1 edition (December 13, 2004)
* Language: English
* ISBN-10: 0444516514

Book Description
Systemic autoimmune diseases can affect both the central and peripheral nervous systems in a myriad of ways and through a heterogeneous number of mechanisms leading to many different clinical manifestations. As a result, neurological complications of these disorders can result in significant morbidity and mortality. Advances in the diagnosis, laboratory investigations, and management of these conditions has placed an increasing burden on the practicing clinician to correctly assess and treat these patients.
This volume of the Handbook of the Systemic Autoimmune Diseases will help the clinician and researcher better understand the current concepts of nervous system involvement from systemic autoimmune disorders, recognize current approaches to diagnosis and treatment, current controversies, and areas that need significant research efforts. It is believed that providing this approach in a single volume will facilitate its use as a frequent resource for all those caring for or investigating these patients and their diseases.
Each chapter follows a consistent outline to provide the reader with important and useful information in an easy-to-navigate manner and is also liberally referenced to provide more primary source material for further consideration. The standardized approach to each chapter will allow the reader to be able to compare and contrast more efficiently the neurological complications of the autoimmune diseases discussed.

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Pulmonary Involvement in Systemic Autoimmune Diseases, Volume 2

Pulmonary Involvement in Systemic Autoimmune Diseases, Volume 2 (Handbook of Systemic Autoimmune Diseases)
by Andrea Doria (Editor), Paolo Pauletto (Editor), Ronald Asherson (Series Editor)

Product Details:
* Hardcover: 314 pages
* Publisher: Elsevier Science (December 16, 2004)
* Language: English
* ISBN-10: 0444516522

Book Description
In this book is found the information essential to diagnosing, managing and treating the lung complications of connective tissue diseases. This is a notoriously difficult area, which continues to puzzle clinicians, despite the fact that these disorders are increasingly frequent (as a result of longer survival in connective tissue disease).
In separate chapters, the major connective tissue diseases are reviewed, with detailed discussion of a variety of lung abnormalities, including pleural disease, parenchymal lung disease and pulmonary vascular disease. There are also invaluable overviews of lung histological and CT appearances in these disorders, and a deeply insightful chapter on drug-induced lung disease in connective tissue disease. The emphasis in this book is on accuracy of evaluation and the construction of a logical management plan, based on disease severity and intrinsic progressiveness.

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Biomarkers of Disease: An Evidence-Based Approach

Biomarkers of Disease: An Evidence-Based Approach
by Andrew K. Trull (Editor), Lawrence M. Demers (Editor), David W. Holt (Editor), Atholl Johnston (Editor), J. Michael Tredger (Editor), Christopher P. Price (Editor)

Product Details:
* Hardcover: 516 pages
* Publisher: Cambridge University Press; 1 edition (June 15, 2002)
* Language: English
* ISBN-10: 0521811023

Book Description
This new publication takes a critical, evidence-based look at the efficacy of new diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. The use of biomarkers is growing, with a steady stream of new products being brought out by the pharmaceutical industry. However, in many cases the evidence which supports the use of these new methods as opposed to traditional biochemical tests has not yet been demonstrated, and it is intended that this volume will help clarify the strengths and weaknesses of using these biomarkers across a wide range of applications and in the various organs of the body. This approach will provide an invaluable overview of the diverse applications of biomarkers in medicine.

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Microbiology & Immunology: Board Review Series

Microbiology & Immunology: Board Review Series
by Arthur G Johnson (Author), Arthur G. Johnson (Author)

Product Details:
* Paperback: 302 pages
* Publisher: Lippincott Williams & Wilkins; 4 edition (December 15, 2001)
* Language: English
* ISBN-10: 0781727707

Book Description
BRS Microbiology and Immunology is a popular volume in the Board Review Series for medical students. Written in a concise, flexible, outline format, this book is intended to cover topics most commonly tested on USMLE. Included are 300 to 500 review questions in the USMLE-style format, and a comprehensive examination. New to the revised Fourth Edition are completely updated content; questions written in vignette format; a page of color plates depicting staining methods; and more information on immunology, parasitology, and fungi.

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Fungal Pathogenesis: Principles and Clinical Applications

Fungal Pathogenesis: Principles and Clinical Applications
by Richard Calderone (Author)

Product Details:
* Hardcover: 762 pages
* Publisher: CRC; 1st edition (October 15, 2001)
* Language: English
* ISBN-10: 0824705688

Book Description
Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens! This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular survival, morphogenesis, adaptation, and properties of major fungal pathogens that contribute to disease. Focuses on human fungal infections, including candidiasis, pneumocystosis, aspergillosis, and cryptococcosis. With over 3700 references to accommodate continuing study, Fungal Pathogenesis · covers natural and acquired immunity, vaccine development, and immune reconstitution · outlines rapid identification of major mycoses utilizing antigen capture and molecular assays · details signaling and phenotypic switching · discusses the value of genomics in validation · highlights state-of-the-art molecular methodologies to study disease-causing organisms · describes available and potential antifungal drug targets and drug development · considers predicting the consequences of drug resistance on patient management · presents topical observations on strain typing and variation · and more! Containing research into the virulence, immunity, diagnosis, and therapy of most common fungal infections, Fungal Pathogenesis is an unparalleled reference for microbiologists, virologists, pathologists and phytopathologists, infectious disease specialists, molecular and cell biologists, biochemists, immunologists, medical mycologists, biotechnologists, and geneticists, and an exceptional text for upper-level undergraduate, graduate, and medical school students in these disciplines.

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Protozoal Abortificients in Farm Ruminants: Guidelines for Diagnosis and Control

Protozoal Abortificients in Farm Ruminants: Guidelines for Diagnosis and Control
by L Ortega-Mora (Editor), B Gottstein (Editor), F Conraths (Editor), D Buxton (Editor)

Product Details
Hardcover: 320 pages
Publisher: Oxford University Press, USA; 1 edition (July 20, 2007)
Language: English
ISBN-10: 1845932110

Book Description
The farm ruminant industry which is at the core of livestock agriculture in Europe and the rest of the world, suffers major economic loss every year due to reproductive dysgenesis. Protozoal diseases cause abortion in ruminants and therefore its diagnosis is vital in improving the health and
welfare of farm livestock. This book is a collective effort from international scientists involved in an EU COST Action. Carefully selected methodologies, presented in a simple and practical form, means laboratories can carry their research out with precision.

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The National Academies Keck Futures Initiative The Genomic Revolution -- Implications for Treatment and Control of Infectious Disease: Working Group

The National Academies Keck Futures Initiative The Genomic Revolution -- Implications for Treatment and Control of Infectious Disease: Working Group Summaries
by The National Academies Keck Futures Initiative Genomics Steering Committee (Author), The National Academies Keck Futures Initiative Genomics Planning Committee (Author), The National Academies (Author)

Product Details
Paperback: 132 pages
Publisher: National Academies Press; 1 edition (April 3, 2006)
Language: English
ISBN-10: 0309101093

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Moffet's Pediatric Infectious Diseases: A Problem-Oriented Approach

Moffet's Pediatric Infectious Diseases: A Problem-Oriented Approach
by Randall G Fisher (Author), Thomas G Boyce (Author)

Product Details
Paperback: 787 pages
Publisher: Lippincott Williams & Wilkins; 4 edition (October 1, 2004)
Language: English
ISBN-10: 0781729432

Book Description
Unlike many texts, which are organized by disease or pathogen, this unique resource presents a problem-oriented approach to the diagnosis and management of infectious diseases in children. All chapters are organized by anatomic syndrome and guide you through each step in the management process--from classifying the patient's illness to recognizing life-threatening emergencies, developing a logical differential diagnosis, pinpointing the disease, and treating the patient. All the features you've come to trust... . Patient-oriented approach helps you focus on the patient rather than the pathogen, and offers a complete review of the diagnostic and treatment process. . Step-by-step guidelines take you logically from evaluation and work-up to diagnosis and therapeutic decision-making. . Expert authors combine the scientific integrity and practicality established by Dr. Moffet, with the latest advances and their own authoritative views. Plus a wealth of NEW MATERIAL... . More comprehensive coverage includes greater detail in all subject areas, as well as new material on pathogens identified since the last edition--including SARS-coronavirus, hantavirus, human metapneumovirus, West Nile virus, and potential agents of bioterrorism. . More treatment-centered approach helps you focus on the therapeutic process--from diagnostic evaluation and testing to treatment selection. . All chapters have been extensively revised and updated, and two new chapters have been added addressing HIV Infection and AIDS, and Congenital Immune Deficiency Syndromes. Discover a patient-centered approach to pediantric infectious disease management. Order your copy of Moffet's Pediatric Infectious Diseases, Fourth Edition today!

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Bacterial Genomes and Infectious Diseases

Bacterial Genomes and Infectious Diseases
by V. L. (Ricky) Chan (Editor), Philip M. Sherman (Editor), Billy Bourke (Editor)

Product Details
Hardcover: 288 pages
Publisher: Humana Press; 1 edition (July 8, 2006)
Language: English
ISBN-10: 158829496X

Book Description
The emergence and reemergence of infectious diseases, an increasing rate of antibiotic-resistant variants of pathogens, and the threat of bioterrorism underscore the importance of bacterial genomes and infectious diseases. Bacterial Genomes and Infectious Diseases presents major findings about bacterial genomes and their impact on strategy and approach for investigating mechanisms of pathogenesis of infectious diseases. This book imparts fundamental knowledge on the structure, organization, and evolution of bacterial genomes. The value and power of comparative genomics and proteomics, bioinformatics, microarrays, and knockout animal models in analyzing genomes, bacteria-host interactions and disease are demonstrated. Also discussed are the genomes of virulent and nonvirulent strains and species, origin and evolution of pathogens, different models of bacteria-host interactions, and diseases mechanisms.

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Management of Infectious Complications in Cancer Patients

Management of Infectious Complications in Cancer Patients
by Gary A. Noskin (Editor)

Product Details
Hardcover: 300 pages
Publisher: Springer; 1 edition (August 31, 1998)
Language: English
ISBN-10: 0792381505

Book Description
Infection is a major cause of morbidity and mortality in patients with neoplastic disease because of compromised host defenses. These defects result in an increased risk of infection and its complications. The nature of the underlying malignancy, the immunodeficiencies associated with it, and the treatments directed against it are all important determinants of infection. In recent years, the introduction of more intensive chemotherapeutic regimes and the widespread use of bone marrow and peripheral stem cell transplantation have changed the pattern of infection in many patients. Furthermore, the increasing use of central venous access devices and antimicrobial prophylaxis has changed the epidemiology of infection in these patients as well. The goal of this volume in the Cancer Treatment and Research series is to emphasize that while the management of infection in cancer patients is common, it is constantly changing. With the increasing complexity of these patients, optimal management requires a multidisciplinary approach. Ultimately, it is hoped that this book will assist clinicians in the diagnosis, management, and prevention of infection in order to optimize care for patients with cancer.

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Growing Fungus

Growing Fungus
by N.A. Gow (Editor), G.M. Gadd

Product Details
Paperback: 496 pages
Publisher: Springer; 1 edition (September 30, 1994)
Language: English
ISBN-10: 0412466007

Book Description
This book brings together recent advances in the cell biology, physiology and genetics of growth and differentiation of filamentous fungi. This is timely in view of the many recent advances that have been achieved through the application of new cytological, biochemical, genetic, and molecular techniques to the study of filamentous fun

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The Fusarium Laboratory Manual

The Fusarium Laboratory Manual
by John F. Leslie (Author), Brett A. Summerell (Author), Suzanne Bullock (Illustrator)

Product Details
Spiral-bound: 388 pages
Publisher: Wiley-Blackwell; Spi edition (June 20, 2006)
Language: English
ISBN-10: 0813819199

Book Description
For the first time in over 20 years, a comprehensive collection of photographs and descriptions of species in the fungal genus Fusarium is available. This laboratory manual provides an overview of the biology of Fusarium and the techniques involved in the isolation, identification and characterization of individual species and the populations in which they occur. It is the first time that genetic, morphological and molecular approaches have been incorporated into a volume devoted to Fusarium identification. The authors include descriptions of species, both new and old, and provide protocols for genetic, morphological and molecular identification techniques.
The Fusarium Laboratory Manual also includes some of the evolutionary biology and population genetics thinking that has begun to inform the understanding of agriculturally important fungal pathogens. In addition to practical “how-to” protocols it also provides guidance in formulating questions and obtaining answers about this very important group of fungi. The need for as many different techniques as possible to be used in the identification and characterization process has never been greater. These approaches have applications to fungi other than those in the genus Fusarium. This volume presents an introduction to the genus Fusarium, the toxins these fungi produce and the diseases they can cause.

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Bacterial Physiology: A Molecular Approach

Bacterial Physiology: A Molecular Approach
by Walid El-Sharoud (Editor)

Product Details
Hardcover: 372 pages
Publisher: Springer; 1 edition (December 18, 2007)
Language: English
ISBN-10: 3540749209

Book Description
The application of new molecular methodologies in the study of bacterial behaviour and cell architecture has enabled new revolutionary insights and discoveries in these areas. While this has also raised a number of scientific mysteries about bacteria, it certainly improved our understanding of these organisms as complex and adaptive entities rather than just simple tiny buckets of enzymes. The value of this recent knowledge in bacterial physiology is not only restricted to fundamental biology, but it also extends to biotechnology and drug-discovery disciplines where understanding cell behaviour and structure is essential for better exploitation of useful bacteria and effective eradication of harmful ones. This makes a new text accommodating recent developments in bacterial physiology highly relevant to a wide range of readership including those interested in basic and applied knowledge.

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HIV-1: Molecular Biology and Pathogenesis: Viral Mechanism

HIV-1: Molecular Biology and Pathogenesis: Viral Mechanisms (Advances in Pharmacology, Volume 48) (Advances in Pharmacology)
by J. Thomas August (Editor), Ferid Murad (Editor), Kuan-Teh Jeang (Editor)

Product Details
* Hardcover: 453 pages
* Publisher: Academic Press; 1 edition (August 2000)
* Language: English
* ISBN-10: 0120329492

Book Description:
The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.
The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.

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Practical Manual of Groundwater Microbiology

Practical Manual of Groundwater Microbiology, Second Edition (Sustainable Water Well)

Product Details:
* Hardcover: 400 pages
* Publisher: CRC; 2 edition (December 17, 2007)
* Language: English
* ISBN-10: 0849385318

Book Description
Although microorganisms can be found virtually anywhere on our planet, from clouds to soils to oceans, they are often poorly understood when examining issues related to groundwater and water wells. Focusing on the impact of microorganisms on groundwater and water wells, Practical Manual of Groundwater Microbiology, Second Edition presents over 75% new material to offer a comprehensive, up-to-date guide on the subject. The first eight chapters provide an overview of microbiology and its importance in groundwaters, exploring natural filters that develop around wells, various bacteria, molds, viruses, sampling procedures, biofouling, biofilms, sequestration strategies, rehabilitation/regeneration practices, and flooding risks. The book also contains a chapter that functions as a self-contained guide, with 79 descriptive illustrations of important concepts integral to the understanding of microbes in groundwater. Numerous appendices, some new to this edition, supply detailed information on more specialized topics, such as microbiological test methods, water sample protocols, regulatory considerations concerning the use of phosphorus in wells, and the application of vegetable oil to lubricate pumps. Chronicling the significant progress made in the field since the publication of its predecessor, this edition provides practical approaches for evaluating the effects of microorganisms and their activities on groundwater and water wells.

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Ocular Infection

Ocular Infection, Second Edition
by David Seal (Author), Uwe Pleyer (Author)

Product Details:
* Hardcover: 384 pages
* Publisher: Informa Healthcare; 2 edition (October 30, 2007)
* Language: English
* ISBN-10: 0849390931

Book Description:
Since the first edition that was published in 1998 we have seen manychanges in ophthalmology from advancements in laser surgery to new techniques in cataract surgery. With these new developing advancements symptoms, diagnosis, and treatments in ocular disease have also begun to change. Early diagnosis and management of ocular infection is essential to avoid the risk of blindness. An understanding of the related disease process and drug therapy is a key aid in achieving this. The updated Ocular Infection Second Edition covers the basic science of ocular infection, as well as its diagnosis and management of ocular disease, and the changes it is going through.

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Immunopharmacology of Free Radical Species

Immunopharmacology of Free Radical Species (Handbook of Immunopharmacology)
by David R. Blake (Author), Paul G. Winyard (Editor)

Product Details
* Hardcover: 301 pages
* Publisher: Academic Pr (July 1995)
* Language: English
* ISBN-10: 0121035204

Book Description
London Hospital Medical College, U.K. Research on the basic mechanisms of free radical processes and injury in various types of diseases. Possible therapeutic strategies. Includes glossary and a key to illustrations. 35 contributors, 7 U.S.

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Proteases of Infectious Agents

Proteases of Infectious Agents
by Ben Dunn (Editor)

Product Details
Hardcover: 282 pages
Publisher: Academic Press; 1st edition (June 15, 1999)
Language: English
ISBN-10: 0124205100

Book Description
Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search.
Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area.
Key Features
* Includes information on the basic biology and function of proteases
* Provides global survey of current research efforts in protease inhibitors
* Illustrates how structure-based drug design targets effective and selective compounds
* Highlights important diseases that provide economically important targets
* Describes the role of proteases as important new targets for drug discovery

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Antimicrobial Resistance and Implications for the 21st Century

Antimicrobial Resistance and Implications for the 21st Century (Emerging Infectious Diseases of the 21st Century)
by I.W. Fong (Editor), Karl Drlica (Editor)

Product Details
Hardcover: 408 pages
Publisher: Springer; 1 edition (October 24, 2007)
Language: English
ISBN-10: 0387724176

Book Description
Antimicrobial resistance can develop in any type of microbe (germ). Microbes can develop resistance to specific medicines. A common misconception is that a persons body becomes resistant to specific drugs. However, it is microbes, not people that become resistant to the drugs. Drug resistance happens when microbes develop ways to survive the use of medicines meant to kill or weaken them. If a microbe is resistant to many drugs, treating the infections it causes can become difficult or even impossible. Someone with an infection that is resistant to a certain medicine can pass that resistant infection to another person. In this way, a hard-to-treat illness can be spread from person to person. In some cases, the illness can lead to serious disability or even death.
This comprehensive, up-to-date volume aims to define issues and potential solutions to the challenges of antimicrobial resistance. The chapter authors are leading international experts on antimicrobial resistance among a variety of bacteria (Streptococcus pneumoniae, enteroccoci, staphylococci, gram-negative bacilli, mycobacteria species) viruses (HIV, herpesviruses), parasites (malaria, leishmaniasis) and fungi (Candida species, fusarium etc.). The chapters will explore the molecular mechanisms of drug resistance, the immunology and epidemiology of resistance strains, clinical implications and implications on research and lack thereof, and prevention and future directions. This volume will also describe the steps that researchers are taking to develop molecular methods for detecting resistance; develop drugs and other means to deal with newly-resistant organisms. A special chapter to address the issues on strategies to limit antimicrobial resistance propagation will be included in this volume.

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Streptococcal Pharyngitis: Optimal Management

Streptococcal Pharyngitis: Optimal Management (Issues in Infectious Diseases)
by J.C. Ed. Pechere (Author)

Product Details
Hardcover: 220 pages
Publisher: S. Karger AG, Basel; 1 edition (2004)
Language: English
ISBN-10: 3805576021

Book Description
Indispensable for primary care physicians, pediatricians and otorhinolaryngologists! Group A streptococcal pharyngitis is one of the most common, but also controversial infections clinicians are faced with every day. Clinical diagnosis is often not specific; laboratory data can be misleading and are frequently misinterpreted. Despite the in vitro effectiveness of penicillin, it does not always eradicate the organism from the upper respiratory tract. Numerous newly introduced antibiotics are expensive or not even available in many countries. In this book, internationally acknowledged experts deal in detail with the complexity of streptococcal pharyngitis and the remaining controversies. It offers an overview of the virulence factors of Streptococcus pyogenes, the pathogenesis of pediatric and adult streptococcal pharyngitis, and the epidemiology of streptococcal pharyngitis in high and low income countries. In addition, the most current concepts of clinical and laboratory diagnosis of streptococcal pharyngitis and its possible suppurative and non-suppurative complications are presented. Further points under discussion are the efficacy of different antibiotic treatments and the cost issues in diagnosis and therapy. Finally, the impact of streptococcal pharyngitis on public health worldwide as well as possible vaccine control strategies are reviewed. This concise publication is a valuable reference for primary care physicians, pediatricians, otolaryngologists, public health authorities, and students in the health care professions.

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