Thursday, February 7, 2008

T Cell Subsets, Volume 83: Cellular Selection, Commitment and Identity

T Cell Subsets, Volume 83: Cellular Selection, Commitment and Identity (Advances in Immunology)
by H. Cantor (Editor), Laurie Glimcher (Editor), Frederick W. Alt (Series Editor)

Product Details
Hardcover: 304 pages
Publisher: Academic Press; 1 edition (May 20, 2004)
Language: English
ISBN-10: 0120224836

Book Description
This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.

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