Autoantibodies

Autoantibodies, Second Edition
By Y. Shoenfeld, M.E. Gershwin, Pier-Luigi Meroni

Product Details
* Hardcover: 872 pages
* Publisher: Elsevier Science; 2 edition (December 18, 2006)
* Language: English
* ISBN-10: 044452763X

Book Description
An updated review of all the most important autoantibodies currently identified in the field of autoimmune diseases.
Autoimmune diseases are characterized by the occurrence of antibodies reacting with self constituents of the body. This exciting new reference is an exhaustive review of the main autoantibodies identified up to now, with particular emphasis on those autoantibodies that display a clinical value. Each chapter is focussed on a single family of autoantibodies by reviewing their historical notes, definition, origin and source(s) of the antigen(s) recognized, genetic associations, pathogenic mechanisms that are mediated, method(s) of detection and clinical utility (disease prevalence/association, diagnostic value, sensitivity and specificity, prognostic value). An ideal reference for anyone involved in the field of autoimmune diseases.

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