Monoclonal Antibodies, Third Edition: Principles and Practice

Monoclonal Antibodies, Third Edition: Principles and Practice
by James W. Goding (Author)

Product Details:
* Hardcover: 492 pages
* Publisher: Academic Press; 3 edition (March 5, 1996)
* Language: English
* ISBN-10: 0122870239

Book Description:

Monoclonal Antibodies now have applications in virtually all areas of biology and medicine, and much of the world's biotechnology industry has its foundations in the exploitation of this technology.
The Third Edition of this well established book meets the needs of both newcomers to the area and experienced researchers, by providing an integrated treatment of both the production and application of monoclonal antibodies. As in previous editions, detailed and critical accounts of the theory, production, purification, fragmentation, storage and radiolabelling of monoclonal antibodies are given, along with descriptions of their use in antigen characterization, affinity chromatography and immunofluorescence. The present volume has been comprehensively updated to cover recent rapid advances, particularly with respect to the applications of molecular biology, the use of antibodies in closing and heterologous expression of genes, immunohistology and phage display libraries. Since the previous edition, there has been a growing trend towards the replacement of procedures using radioactive isotopes, and the current edition incorporates these newer technologies.
The text is oriented towards problems solving, and makes it easy to adapt each procedure to individual needs. Extensive cross-referencing, a glossary and a comprehensive index make this book an essential reference.
This book will be vital both for laboratories already producing or using monoclonal antibodies, and for workers in many disciplines who are contemplating their use.

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The Biofilm Primer

The Biofilm Primer (Springer Series on Biofilms)
by J. William Costerton (Author)

Product Details:
* Hardcover: 207 pages
* Publisher: Springer; 1 edition (April 19, 2007)
* Language: English
* ISBN-10: 3540680217

Book Description
This book details the widely accepted hypothesis that the majority of bacteria in virtually all ecosystems grow in matrix-enclosed biofilms. The author, who proposed this biofilm hypothesis, uses direct evidence from microscopy and from molecular techniques, presenting cogent reasons for moving beyond conventional culture methods that dominated microbiology throughout the last century. Bacteria grow predominantly in biofilms in all natural, engineered, and pathogenic ecosystems, and this book provides a solid basis for the understanding of bacterial processes in environmental, industrial, agricultural, dental and medical microbiology. Using a unique "ecological" perspective, the author explores the commensal and pathogenic colonization of human organ systems.

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Immunology Guidebook

Immunology Guidebook
by Julius Cruse (Editor), Robert Lewis (Editor), Huan Wang (Editor)

Product Details:
* Hardcover: 1000 pages
* Publisher: Academic Press (August 9, 2004)
* Language: English
* ISBN-10: 012198382X

Book Description
The Immunology Guidebook provides an easily accessible text-reference to the more
up-to-date and difficult concepts in the complex science of immunology. It aims to demystify basic concepts and specialised molecular and cellular interactions. Its 18 chapters offer a logical and sequential presentation where much of the data is displayed in carefully designed tables. This book is intended for immunology students, researchers, practitioners and basic biomedical scientists.
* Tables provide a quick reference to difficult to find immunology data
* A distillate of the latest information on immunogenetics of the human MHC associated with tissue transplantation
* Information boxes featurw related web resources

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Microbial Processes and Products

Microbial Processes and Products(Methods in Biotechnology)
by José-Luis Barredo (Editor)

Product Details:
* Hardcover: 536 pages
* Publisher: Humana Press; 1 edition (February 7, 2005)
* Language: English
* ISBN-10: 1588295486

Book Description
Outstanding experts in the use of microorganisms as cell factories describe in step-by-step detail their best laboratory procedures for a wide range of processes and products mediated by microorganisms. The diverse chemicals and biochemicals produced can be used in human health, nutrition, and environmental protection, and include semisynthetic derivatives of cephalosporins, erythromycin, antitumor compounds, plasmids for gene therapy and DNA vaccination , L-lysine, Vitamins B2 and B12, the sweet-tasting protein thaumatin, the carotenoids ß-carotene and astaxanthin, the polysaccharide gellan, and a bacteria-producing bacteria for sausage fermentation, and many more. Also illustrated are the uses of phenylacetyl-CoA catabolon for the enzymatic synthesis of penicillins, aromatic biotransformation, syntheses of novel bioplastics, biosensor design, and the synthesis of drug vehicles. This book offers laboratory and industrial scientists a wealth of readily reproducible techniques for the microbial generation of biochemical products serving human health, nutrition, and environmental protection.

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Medical Immunology (Stites)

Medical Immunology
by Tristram G. Parslow (Author), Daniel P. Stites (Author), Abba I. Terr (Editor), John B. Imboden (Author)

Product Details:
* Paperback: 814 pages
* Publisher: McGraw-Hill/Appleton & Lange; 10 edition (March 23, 2001)
* Language: English
* ISBN-10: 0838563007

Book Description
* Emphasizes both the basic and clinical aspects of immunology that promotes understanding of core concepts and provides clinical correlations to medical practice
* Logical progression from normal immune function to laboratory abnormalities and clinical diseases
* Problem-oriented approach to clinical disorders caused by immunological disruption

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Parasitic Flatworms: Molecular Biology, Biochemistry, Immunology and Physiology

Parasitic Flatworms: Molecular Biology, Biochemistry, Immunology and Physiology
by A. G. Maule (Editor), N. J. Marks (Editor)

Product Details:
* Hardcover: 480 pages
* Publisher: CABI Publishing; 1 edition (August 21, 2006)
* Language: English
* ISBN-10: 0851990274

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Human Papillomaviruses: Methods and Protocols

Human Papillomaviruses: Methods and Protocols (Methods in Molecular Medicine)
by Clare Davy (Editor), John Doorbar (Editor)

Product Details:
* Hardcover: 512 pages
* Publisher: Humana Press; 1 edition (September 1, 2005)
* Language: English
* ISBN-10: 1588293734

Book Description
Leading basic researchers and clinical scientists describe in detail a wide variety of established and cutting-edge techniques they have developed to study the lifecycle and biological properties of the human papillomavirus. The authors use these readily reproducible methods, ranging from PCR to propagation of HPV in vitro, to detect and type papillomavirus infections, study the papillomavirus lifecycle, and to produce and functionally analyze papillomavirus proteins. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

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DNA Viruses: Methods and Protocols

DNA Viruses: Methods and Protocols (Methods in Molecular Biology)
by Paul M. Lieberman (Editor)

Product Details:
* Hardcover: 512 pages
* Publisher: Humana Press; 1 edition (October 22, 2004)
* Language: English
* ISBN-10: 158829353X

Book Description
A compendium of readily reproducible and novel methods to manipulate DNA viruses and characterize their varied biological properties. The authors emphasize techniques for viral detection and genetics, but also include methods for structure determination, gene expression, replication, pathogenesis, complex cellular models, recombinant genetics, and computational/systems approaches. Wide-ranging and highly practical, DNA Viruses: Methods and Protocols will stimulate new directions in virology research with its novel strategies for engineering viral vectors in gene therapy, and its advanced approaches for detecting viruses in human disease.

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Bacterial and Eukaryotic Porins: Structure, Function, Mechanism

Bacterial and Eukaryotic Porins: Structure, Function, Mechanism
by Roland Benz (Editor)

Product Details:
* Hardcover: 382 pages
* Publisher: Wiley-VCH (October 8, 2004)
* Language: English
* ISBN-10: 3527307753

Book Description
This first book dedicated to the topic relates the known physiological functions of porins to their molecular structure and mechanism, as documented by various in vitro and in vivo methods, including the generation of null mutants in mice.
For the first time, it brings together biophysical evidence with studies performed in a cellular context, presenting a unified picture of the fundamental importance of porins for cellular function.
With 16 contributions by an interdisciplinary team of leading porin researchers, this reference is essential reading for every molecular or structural biologist with an interest in this essential protein family.

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Dubois' Lupus Erythematosus

Dubois' Lupus Erythematosus
by Daniel J Wallace (Author), Bevra Hannahs Hahn (Author)

Product Details:
* Hardcover: 1440 pages
* Publisher: Lippincott Williams & Wilkins; 7 edition (October 1, 2006)
* Language: English
* ISBN-10: 0781793947

Book Description
Established for forty years as the definitive reference on lupus, Dubois' Lupus Erythematosus is now in its thoroughly revised, updated Seventh Edition. More than ninety distinguished contributing authors--twenty of them new to this edition--provide comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. This edition focuses on evidence-based findings, treatment consensuses, and practical clinical information. New chapters cover cytokines and interferons, pathogenesis of atherosclerosis, immune tolerance, clinical indices in assessment of lupus, mixed connective tissue disease, reproductive issues, fibromyalgia, gender-related issues, and biomarkers.

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Horizontal Gene Transfer

Horizontal Gene Transfer, Second Edition
by Michael Syvanen (Author), Clarence I. Kado (Author)

Product Details:
* Hardcover: 445 pages
* Publisher: Academic Press; 2 edition (January 2002)
* Language: English
* ISBN-10: 0126801266

Book Description:
The second edition of Horizontal Gene Transfer has been organized to provide a concise and up-to-date coverage of the most important discoveries in this fascinating field. Written by the most prominent gene transfer and genome analytical scientists, this book details experimental evidence for the phenomenon of horizontal gene transfer and discusses further evidence provided by the recent completion of genomic sequences from Archea, Bacteria, and Eucarya members. The relevance of horizontal gene transfer to plant and metazoan taxonomy, GM foods, antibiotic resistance, paleontology, and phylogenetic reconstruction is also explored. Horizontal Gene Transfer is essential for microbiologists, geneticists, biochemists, evolutionary biologists, infectious disease specialists, paleontologists, ecologists, and researchers working in plant/animal systematics and agriculture with an interest in gene transfer. This includes scientific researchers from government and industry concerned with the release of genetically modified organisms.

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Microbiologically Influenced Corrosion

Microbiologically Influenced Corrosion (Wiley Series in Corrosion)
by Brenda J. Little (Author), Jason S. Lee (Author)

Product Details:
* Hardcover: 279 pages
* Publisher: Wiley-Interscience (March 30, 2007)
* Language: English
* ISBN-10: 0471772763

Book Description
A multi-disciplinary, multi-industry overview of microbiologically influenced corrosion, with strategies for diagnosis and control or prevention
Microbiologically Influenced Corrosion helps engineers and scientists understand and combat the costly failures that occur due to microbiologically influenced corrosion (MIC). This book combines recent findings from diverse disciplines into one comprehensive reference. Complete with case histories from a variety of environments, it covers:
* Biofilm formation
* Causative organisms, relating bacteria and fungi to corrosion mechanisms for groups of metals
* Diagnosing and monitoring MIC
* Electrochemical techniques, with an overview of methods for detection of MIC
* The impact of alloying elements, including antimicrobial metals, and design features on MIC
* MIC of non-metallics
* Strategies for control or prevention of MIC, including engineering, chemical, and biological approaches

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Macrolide Antibiotics: Chemistry, Biology, and Practice

Macrolide Antibiotics: Chemistry, Biology, and Practice, Second Edition
by Satoshi Omura (Editor)

Product Details:
* Hardcover: 768 pages
* Publisher: Academic Press; 2 edition (June 2002)
* Language: English
* ISBN-10: 0125264518

Book Description:
Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treament.

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Molecular Microbiology Laboratory: A Writing-Intensive Course

Molecular Microbiology Laboratory: A Writing-Intensive Course
by Walt Ream (Author), Bruce Geller (Author), Janine Trempy (Author), Katharine G. Field (Author)

Product Details:
* Plastic Comb: 268 pages
* Publisher: Academic Press; Spi edition (February 2003)
* Language: English
* ISBN-10: 012583991X

Book Description
Molecular Microbiology Laboratory is designed to teach molecular biology techniques to upper level undergraduates majoring in the life sciences. An extremely detailed lab preparation manual for teaching assistants accompanies the lab book and contains a general discussion of scientific writing and critical reading, as well as detailed instructions for preparation and peer review of lab reports. Each experimental unit is accompanied by a number of additional writing exercises based upon primary journal articles. The studies in these articles employ the techniques that the students are learning in the lab exercises, which reinforces their understanding of the material. These are techniques that students in any biological science will need to know, making this manual applicable to any life science curriculum.
Key Features
* Not a typical cookbook lab exercise, offers students the excitement and intellectual challenge of characterizing true unknowns. They could discover a new species!
* Success rate greater than 85% for the entire experiment, even with very inexperienced students.
* The ONLY manual that incorporates writing exercises into the curriculum.
* Co-authored by Dr. Janine Trempy, one of four senior editors of the Journal of Microbiology Education, published by the American Society for Microbiology.
Book Info
Laboratory manual designed to teach molecular biology techniques commonly used in the life sciences. Incorporates writing exercises as well as laboratory procedures, includes general discussion of scientific writing, and provides instructions for the preparation of lab results. Expanded-outline format.

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Morror

In Situ Hybridization in Electron Microscopy

In Situ Hybridization in Electron Microscopy (Methods in Visualization)
by Gerard Morel (Author), Annie Cavalier (Author), Lynda Williams (Author)

Product Details:
* Hardcover: 472 pages
* Publisher: CRC (January 30, 2001)
* Language: English
* ISBN-10: 0849300444

Book Description
In situ hybridization is a technique that allows for the visualization of specific DNA and RNA sequences in individual cells, and is an especially important method for studying nucleic acids in heterogeneous cell populations. in situ Hybridization in Electron Microscopy reviews the three main methods and describes the different stages in detail: the preparation of tissue, pretreatment, hybridization, and visualization of the hybridization products. The book includes principles of methodology and practical protocols, along with specific comments, in a two-column user-friendly format. With nearly 150 figures and tables, this book is an essential companion for any researcher in this field.

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Nutrition and AIDS

Nutrition and AIDS, Second Edition
by Ronald R. Watson (Editor)

Product Details:
* Hardcover: 256 pages
* Publisher: CRC; 2 edition (September 19, 2000)
* Language: English
* ISBN-10: 0849302722

Book Description:
This new edition of Nutrition and AIDS brings to the forefront the most recent advances in understanding the nutritional deficiencies of AIDS and HIV-positive patients. It is a timely look at what dietary materials, supplements, and foods may benefit or treat AIDS, as well as nutrient deficiencies that may accelerate progression to AIDS and death. The book offers a variety of alternative dietary and herbal remedies, including some that have been tested in animals and humans to simulate immune defense or compensate for changes induced by HIV infection.

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Rabies

Rabies
by Alan C. Jackson (Editor), William H. Wunner (Editor)

Product Details:
* Hardcover: 485 pages
* Publisher: Academic Press (April 2002)
* Language: English
* ISBN-10: 0123790778

Book Description:
Rabies offers a complete account of one of the oldest known diseases threatening public health today. Unlike most research-oriented descriptions of rabies, this book provides a narrative about the disease and its etiologic agent, encompassing the historical background to recent developments. The emphasis on the basic biology and molecular virology of the disease is intended to convey an understanding of the underlying mechanisms involved in the disease - essential information for diagnosis and prevention strategies. Current methods used in defining geographic origins and animal species of rabies viruses in wildlife are presented, along with diagnostic methods for identifying the strain of virus based on its genomic sequence and antigenic structure. The latest approved methods for controlling rabies in wildlife species are also covered. This account of rabies will interest clinicians, public health advisors, epidemiologists, research scientists, and anyone involved in diagnosing, treating, controlling, and preventing this disease.

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Infection and Autoimmunity

Infection and Autoimmunity
by Y. Shoenfeld (Editor), Noel Richard Rose (Editor)

Product Details:
* Hardcover: 768 pages
* Publisher: Elsevier Science (November 2, 2004)
* Language: English
* ISBN-10: 0444512713

Book Description
Autoimmune diseases are conditions where the immune system attacks the body organs instead of foreign invaders. This book deals with the various mechanisms which infectious agents can trigger autoimmunity such as molecular mimicry, polyclonal activation and others. An overview is given with regard to bacteria, viruses and parasites associated with autoimmunity. There is a summary on classical autoimmune diseases and the infecting agents that can induce them.

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Mirror

Microbial Genomes (Infectious Disease)
by Claire M. Fraser (Editor), Timothy Read (Editor), Karen E. Nelson (Editor)

Product Details:
* Hardcover: 552 pages
* Publisher: Humana Press; 1 edition (April 9, 2004)
* Language: English
* ISBN-10: 1588291898

Book Description
This collection of diverse articles by the pioneers of modern genomics takes stock of the current state of the field and elucidates the contribution that sequencing genomes has made to our understanding of microbial metabolism and evolution. Through twenty-eight thought-provoking chapters, the authors describe some of the most common computational methods and their applications to studying pathogenic microorganisms, show how genomics can be used to reconstruct the history and dynamism of the microbial world, and discuss issues as diverse as reconstruction of metabolic pathways, cell cycle processes, microbial evolution, metagenomics, and vaccine development. Additional chapters deal with microarrays and expression analysis and the role of genomic in drug discovery.

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Interferon Methods and Protocols

Interferon Methods and Protocols (Methods in Molecular Medicine)
by Daniel J. J. Carr (Editor)

Product Details:
* Hardcover: 240 pages
* Publisher: Humana Press; 1 edition (June 1, 2005)
* Language: English
* ISBN-10: 1588294188

Book Description
A compendium of optimized methods to measure type I interferon efficacy as an antiproliferative or an antiviral agent. These cutting-edge techniques range from the simple to the highly complex and serve to illuminate the signaling cascades and the activation of enzymatic pathways prompted by interferon. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
State-of-the-art and highly practical, Interferon Methods and Protocols offers researchers powerful tools not only to ascertain the functions of IFN-stimulatory gene products, but also to identify additional molecular pathways that will clarify our understanding of the many biological events influenced by IFNs.

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Microbial Root Endophytes

Microbial Root Endophytes (Soil Biology)
by Barbara J.E. Schulz (Editor), Christine J.C. Boyle (Editor), Thomas N. Sieber (Editor)

Product Details:
* Hardcover: 367 pages
* Publisher: Springer; 1 edition (September 15, 2006)
* Language: English
* ISBN-10: 3540335250

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The Fungi

The Fungi, 2nd Edition
by Michael J. Carlile (Author), Sarah C. Watkinson (Author), Graham W. Gooday (Author)

Product Details:
* Paperback: 588 pages
* Publisher: Academic Press; 2nd edition (February 2001)
* Language: English
* ISBN-10: 0127384464

Book Description:
The fungi are one of the great groups of living organisms, comparable in numbers of species, diversity and ecological significance with animals, plants, protists and bacteria. This textbook deals with all fundamental and applied aspects of mycology, illustrated by reference to well studied species from major fungal groups. Since the publication of the first edition of The Fungi, there have been many important advances in the field of mycology. This second up-to-date edition has been revised and substantially expanded, and incorporates the application of methods of molecular biology, especially DNA technology to mycology.
KEY FEATURES:
* Question and answer section at the end of each chapter
* Modern classification based on Molecular phylogeny
* Detail of the recent increased understanding of the organelles and processes involved in hyphal growth
* New molecular understanding of mating type genes
* The latest on molecular recognition in the infection process
* The use of DNA technology in engineering plant resistance to fungal diseases
* New section on medical mycology
* Fungal mycology in animals
* The latest on the use of genetically manipulated fungi to produce products earlier obtained from mammals.

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Infection And Inflammation: Impacts on Oncogenesis

Infection And Inflammation: Impacts on Oncogenesis (Contributions to Microbiology)
by Thomas Dittmar (Editor), Kurt S. Zaenker (Editor), Axel Schmidt (Editor)

Product Details:
* Hardcover: 246 pages
* Publisher: S. Karger AG (Switzerland); 1ST edition (May 5, 2006)
* Language: English
* ISBN-10: 3805580649

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Antibiotics in Laboratory Medicine: Making a Difference

Antibiotics in Laboratory Medicine: Making a Difference
by Victor Lorian (Author)

Product Details:
* Hardcover: 832 pages
* Publisher: Lippincott Williams & Wilkins; 5 edition (March 1, 2005)
* Language: English
* ISBN-10: 0781749832

Book Description
Implement the most current science and practice in antimicrobial research. Now, find the newest approaches for evaluating the activity, mechanisms of action, and bacterial resistance to antibiotics with this completely updated, landmark reference.
Turn to this comprehensive reference for groundbreaking evidence on the molecular link between chemical disinfectants, sterilants, and antibiotics. On the latest methods for detecting antibacterial resistance genes in the clinical laboratory, and antivirogram use to select the most active antiviral components against your patient's HIV.

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The First Miracle Drugs: How the Sulfa Drugs Transformed Medicine

The First Miracle Drugs: How the Sulfa Drugs Transformed Medicine
by John E. Lesch (Editor)

Product Details:
* Hardcover: 376 pages
* Publisher: Oxford University Press, USA; 1 edition (September 28, 2006)
* Language: English
* ISBN-10: 019518775X

Book Description
In the decade from 1935-1945, while the Second World War raged in Europe, a new class of medicines capable of controlling bacterial infections launched a therapeutic revolution that continues today. The new medicines were not penicillin and antibiotics, but sulfonamides, or sulfa drugs. The sulfa drugs preceded penicillin by almost a decade, and during World War II they carried the main therapeutic burden in both military and civilian medicine. Their success stimulated a rapid expansion of research and production in the international pharmaceutical industry, raised expectations of medicine, and accelerated the appearance of new and powerful medicines based on research. The latter development created new regulatory dilemmas and unanticipated therapeutic problems. The sulfa drugs also proved extraordinarily fruitful as starting points for new drugs or classes of drugs, both for bacterial infections and for a number of important non-infectious diseases. This book examines this breakthrough in medicine, pharmacy, and science in three parts. Part I shows that an industrial research setting was crucial to the success of the revolution in therapeutics that emerged from medicinal chemistry. Part II shows how national differences shaped the reception of the sulfa drugs in Germany, France, Britain, and the United States. The author uses press coverage of the day to explore popular perceptions of the dramatic changes taking place in medicine. Part III documents the impact of the sulfa drugs on the American effort in World War II. It also shows how researchers came to an understanding of how the sulfa drugs worked, adding a new theoretical dimension to the science of pharmacology and at the same time providing a basis for the discovery of new medicinal drugs in the 1940s, 1950s, and 1960s. A concluding chapter summarizes the transforming impact of the sulfa drugs on twentieth-century medicine, tracing the therapeutic revolution from the initial breakthrough in the 1930s to the current search for effective treatments for AIDS and the new horizons opened up by the human genome project and stem cell research.

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Algal Culturing Techniques

Algal Culturing Techniques
by Robert A. Andersen (Editor)

Product Details:
* Hardcover: 578 pages
* Publisher: Academic Press (January 21, 2005)
* Language: English
* ISBN-10: 0120884267

Book Description
Algal Culturing Techniques is a comprehensive reference on all aspects of the isolation and cultivation of marine and freshwater algae, including seaweeds. It is divided into seven parts that cover history, media preparation, isolation and purification techniques, mass culturing techniques, cell counting and growth measurement techniques, and reviews on topics and applications of algal culture techniques for environmental investigations.
Algal Culturing Techniques was developed to serve as both a new textbook and key reference for phycologists and others studying aquatic systems, aquaculture and environmental sciences. Students of algal ecology, marine botany, marine phycology, and microbial ecology will enjoy the hands-on methodology for culturing a variety of algae from fresh and marine waters. Researchers in industry, such as aquaculture, pharmaceutical, foodstuffs, and biotechnology companies will find an authoritative and comprehensive reference.

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* Sponsored by the Phycological Society of America
* Features color photographs and illustrations throughout
* Describes culturing methods ranging from the test tube to outdoor ponds and coastal seaweed farms
* Details isolation techniques ranging from traditional micropipette to automated flow cytometeric methods
* Includes purification, growth, maintenance, and cryopreservation techniques
* Highlights methods for estimating algal populations, growth rates, isolating and measuring algal pigments, and detecting and culturing algal viruses
* Features a comprehensive appendix of nearly 50 algal culture medium recipes
* Includes a glossary of phycological terms

Primary Immunodeficiency Diseases: A Molecular & Cellular Approach

Primary Immunodeficiency Diseases: A Molecular & Cellular Approach
by Hans D. Ochs (Author), C. I. Edward Smith (Author), Jennifer M. Puck (Author)

Product Details:
* Hardcover: 776 pages
* Publisher: Oxford University Press, USA; 2 edition (August 10, 2006)
* Language: English
* ISBN-10: 019514774X

Book Description
The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in, certain conditions, an icreased rate of malignancies and autoimmune disirders.Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced., the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document a the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.

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Novel Vaccination Strategies

Novel Vaccination Strategies
by Stefan H. E. Kaufmann (Editor)

Product Details:
* Hardcover: 670 pages
* Publisher: Wiley-VCH (April 9, 2004)
* Language: English
* ISBN-10: 3527305238

Book Description:
The world of vaccines traditionally has been considered to consist of a very limited number of tools for immunizing humans and animals. In recent years, however, advances in immunology and molecular genetics have permitted the development of innovative ways of inducing protective immunity. Centuries after Jenner's experiment with cowpox, vaccines have become extremely sophisticated weapons against infectious diseases. This book thoroughly reviews our understanding of the immunologic response to infectious diseases and the many recent advances in the development of vaccines. A number of experimental vaccines are discussed, and future strategies that may change the way in which infectious and other diseases will be prevented are also presented. Stefan Kaufmann, who is the founding director of the Max Planck Institute for Infection Biology in Berlin, has brought together a group of experts in various fields of vaccinology from Europe, the United States, and Australia for this challenging project. Immunologists, developers of vaccines, clinical-trial specialists, and molecular biologists will find this book to be of interest. It begins with an engaging presentation about the challenges involved in the development of vaccines, including the search for serologic correlates of protection and the difficulty of developing vaccines for the many pathogens that are not associated with such serologic markers. Another section illustrates in detail the immunologic response to vaccines, beginning with the body's recognition of pathogens and ending with the mechanisms of immunologic memory. An outstanding section of the book is dedicated to adjuvants and vaccine vectors. An example is the use of the virus vector as a sort of Trojan horse, which can be engineered specifically for carrying the vaccine into the living organism. I recommend this book to microbiologists, epidemiologists, and practitioners who administer vaccines. Indeed, reading the chapters that compare the traditional way of preparing and delivering vaccines with new techniques that are likely to be implemented in the near future is fascinating for all specialists. Of particular interest is the discussion of DNA vaccines, which may be used to prevent certain congenital or neonatal infections, such as infection with the herpes simplex virus or the human immunodeficiency virus (HIV). Also intriguing is the discussion of efforts to engineer types of living plants that would carry molecules capable of inducing an immune response. The possibility of producing large quantities of vaccine by this means would revolutionize preventive strategies, especially in developing countries. The book also covers the efforts to tailor vaccines to eradicate the world's major infectious killers, namely malaria, tuberculosis, and HIV. Advances in the development of vaccines against Helicobacter pylori and bioterror agents are also covered in this comprehensive book. The final section on the safety and economic impact of vaccines is somewhat disappointing; this is a topic that merits a book in itself. Nonetheless, this section serves to remind us of the high priority that should be given to the safety of vaccines, of the need to provide accurate information to the public, and of the importance of vaccines in preventing disease and improving the health of the general population.

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Lactoferrin: Natural - Multifunctional - Antimicrobial

Lactoferrin: Natural - Multifunctional - Antimicrobial
by Narian Naidu (Author)

Product Details:
* Paperback: 184 pages
* Publisher: CRC; 1st edition (June 9, 2000)
* Language: English
* ISBN-10: 0849309093

Book Description
Lactoferrin is emerging as one of the effective natural antimicrobial intervention in food safety and preservation. Explored in-depth, Lactoferrin: Natural - Multifunctional - Antimicrobial provides you with an introduction to microbial blocking technology and explores its potential as a novel antimicrobial intervention in the multi-hurdle approach to food safety. This book consolidates the science and technological developments in the fast growing area of lactoferrin research.

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Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management

Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management
by Alireza Minagar (Editor), J. Steven Alezander (Editor)

Product Details:
* Hardcover: 450 pages
* Publisher: Humana Press; 1 edition (June 1, 2005)
* Language: English
* ISBN-10: 1588294242

Book Description
A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidois, HIV-Associated dementia, and HTLV-associated neurological disorders.

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Chemokines and Viral Infection

Chemokines and Viral Infection (Current Topics in Microbiology and Immunology)
by T.E. Lane (Editor)

Product Details:
* Hardcover: 160 pages
* Publisher: Springer; 1 edition (April 11, 2006)
* Language: English
* ISBN-10: 3540292071

Book Description
Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. Within a relatively short period of time, early participants within the field determined that these proteins displayed distinct and conserved structural features and exerted potent chemotactic effects on defined lymphocyte subsets. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. The host response to viral infection represents a well-orchestrated ballet consisting of numerous participants with diverse roles in defense but with the ultimate goal of generating virus-specific lymphocytes whose job is to control and eliminate the invading viral pathogen from infected tissues. Over the years, an emerging picture has developed that indicates that chemokines and their receptors are intimately involved in development of effective host responses to viral pathogens. Chemokine expression is now associated with all facets of defense against viral infection including linking innate and adaptive immune responses.

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Dictionary of Parasitology

Dictionary of Parasitology
by Peter J. Gosling (Author)

Product Details:
* Hardcover: 408 pages
* Publisher: CRC (June 24, 2005)
* Language: English
* ISBN-10: 0415308550

Book Description
The Dictionary of Parasitology reflects current practice in all aspects of parasitology and includes spellings, punctuation, abbreviations, acronyms, symbols, nomenclature, prefixes, and suffixes. It assigns entries to the primary divisions of parasitology: human, veterinary, plant, insect, or fish. Including more than 11,500 entries, often with referral to related terms, as well as a wealth of other relevant information, this work provides the depth of knowledge that makes it an informative and useful volume for beginners and experts, as well as for writers and editors of scientific texts. Entries cover control measures, immunology, physiology, pharmacology, etc

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Microbiologically Influenced Corrosion

Microbiologically Influenced Corrosion (Wiley Series in Corrosion)
by Brenda J. Little (Author), Jason S. Lee (Author)

Product Details:
* Hardcover: 279 pages
* Publisher: Wiley-Interscience (March 30, 2007)
* Language: English
* ISBN-10: 0471772763

Book Description
A multi-disciplinary, multi-industry overview of microbiologically influenced corrosion, with strategies for diagnosis and control or prevention
Microbiologically Influenced Corrosion helps engineers and scientists understand and combat the costly failures that occur due to microbiologically influenced corrosion (MIC). This book combines recent findings from diverse disciplines into one comprehensive reference. Complete with case histories from a variety of environments, it covers:
* Biofilm formation
* Causative organisms, relating bacteria and fungi to corrosion mechanisms for groups of metals
* Diagnosing and monitoring MIC
* Electrochemical techniques, with an overview of methods for detection of MIC
* The impact of alloying elements, including antimicrobial metals, and design features on MIC
* MIC of non-metallics
* Strategies for control or prevention of MIC, including engineering, chemical, and biological approaches
This is a valuable, all-inclusive reference for corrosion scientists, engineers, and researchers, as well as designers, managers, and operators.

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The Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins, Third Edition
by Joseph E. Alouf (Editor), Michel R. Popoff (Editor)

Product Details:
* Hardcover: 1072 pages
* Publisher: Academic Press; 3 edition (December 19, 2005)
* Language: English
* ISBN-10: 0120884453

Book Description:
Every medical school and university library must have a copy...it will be a worthwhile investment and a treasure trove of information.
- Cyril J. Smith, Trinity College Dublin, Ireland for CLINICAL INFECTIOUS DISEASES (Sept 2006)

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Handbook of Media for Environmental Microbiology

Handbook of Media for Environmental Microbiology, Second Edition
by Ronald M. Atlas (Author)

Product Details:
* Hardcover: 672 pages
* Publisher: CRC; 2 edition (March 29, 2005)
* Language: English
* ISBN-10: 0849335604

Book Description
The second edition of a bestseller, this book provides a comprehensive reference for the cultivation of bacteria, Archaea, and fungi from diverse environments, including extreme habitats. Expanded to include 2,000 media formulations, this book compiles the descriptions of media of relevance for the cultivation of microorganisms from soil, water, and air. The format allows easy reference to the information needed to prepare media for the cultivation of microorganisms required for environmental analysis, including the determination of water safety. The media are organized alphabetically, and each listing includes medium composition, instructions for preparation, commercial sources, and uses.

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Handbook of Microbiological Media for the Examination of Food

Handbook of Microbiological Media for the Examination of Food, Second Edition
by Ronald M. Atlas (Author)

Product Details:
* Hardcover: 464 pages
* Publisher: CRC; 2 edition (January 13, 2006)
* Language: English
* ISBN-10: 0849335612

Book Description
To meet society's increasing emphasis on food safety during production and storage, this handbook provides in-depth descriptions of a tremendous range of media used for the cultivation of potential foodborne pathogens and food-spoilage microorganisms. This new edition includes FDA recommendations and features newly developed media used to diagnose recently emerging foodborne diseases. In consideration of the new FDA Hazard Analysis and Critical Control Point directive, the Handbook of Microbiological Media for the Examination of Food, Second Edition also provides an appendix with charts illustrating the appropriate required analyses for the microexamination of foods.

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Macrophages: A Practical Approach

Macrophages: A Practical Approach (Practical Approach Series)
by Donna M. Paulnock (Editor)

Product Details:
* Paperback: 232 pages
* Publisher: Oxford University Press, USA (October 23, 2000)
* Language: English
* ISBN-10: 0199636885

Book Description
Macrophages are an important part of the immune response and are characterized by their ability to phagocytose foreign matter. However the difficulties involved in macrophage isolation mean they are some of the body's least explored cells. Macrophage Methodology describes how to isolate moderate to high yields of viable cells from a variety of specific tissue sites under both normal and pathological conditions and then goes on to give protocols for macrophage purification. The third chapter covers techniques used to identify and measure endocytic and phagocytic capabilities using immunochemistry and fluorescent analysis. Chapter four identifies the key issues relating to the study of macrophages as antigen presenting cells and has protocols for the major assays used to measure antigen processing and presentation. Also covered are the theoretical and practical issues related to the processing and presentation of intracellular pathogens for which macrophages are the major host cell. The methods described for measuring macrophage secretory products concentrate on bioassays for molecules where no ELISA is available. The next two chapters cover measuring macrophage activity in vitro and in vivo. Finally methods are described for the analysis of gene expression in macrophages. A variety of broad techniques have been brought together in one affordable volume to make Macrophage Methodology an essential buy for anyone studying macrophages.

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The Pathological Protein: Mad Cow, Chronic Wasting, and Other Deadly Prion Diseases

The Pathological Protein: Mad Cow, Chronic Wasting, and Other Deadly Prion Diseases
by Philip Yam (Author)

Product Details:
* Paperback: 304 pages
* Publisher: Springer; 1 edition (July 5, 2006)
* Language: English
* ISBN-10: 0387955089

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Medical Virology

Medical Virology, Fourth Edition
by D. E. White (Author), Frank J. Fenner (Author)

Product Details:
* Hardcover: 603 pages
* Publisher: Academic Press; 4 edition (January 15, 1994)
* Language: English
* ISBN-10: 0127466428

Book Description:
Medical Virology first appeared in 1970 and was immediately hailed as a classic. The Fourth Edition has been completely updated, substantially rewritten, and considerably expanded. Acknowledging that today's students possess a more sophisticated background of molecular and cellular biology, the book is pitched a little higher than was the third edition. Nevertheless, it maintains the exceptionally high standards of the three previous editions, including the now famous user-friendly style. Hundreds of instructive diagrams and succinct tables smooth the path for the reader. Extensive lists of recent authoritative reviews at the end of each of the 36 chapters simplifies the reader's entry into the scientific literature. Throughout, the focus is on fundamental principles, mechanisms and basic facts, rather than on overwhelming detail.
Part I of the book, expanded to over 400 pages, comprises in effect a self-contained overview of the Principles of Virology. Part II, entitled Viruses of Humans, deals comprehensively with all the families of human viruses. Extensive coverage is given to the molecular biology of the viruses and of viral replication, pathogenesis and immunity, clinical features of all important diseases caused by all viruses affecting humans, the latest laboratory diagnostic methods, epidemiology and control, including chemotherapy and vaccines.
This lucid and concise yet comprehensive text is admirably suited to the needs not only of advanced students of science and medicine but also particularly of postgraduate students, teachers, and research workers in all areas of virology.

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Antimicrobials in Food

Antimicrobials in Food, Third Edition
by P. Michael Davidson (Editor), John N. Sofos (Editor), A. Larry Branen (Editor)

Product Details:
* Hardcover: 720 pages
* Publisher: CRC; 3 edition (April 28, 2005)
* Language: English
* ISBN-10: 0824740378


Book Description:
This book forms a comprehensive reference on naturally occurring and added antimicrobials in food, focusing on those used for preservation. It provides detailed descriptions of the activities, mechanisms of action, applications, regulations, toxicology, and assays of nearly every recognized antimicrobial. This edition has been updated to reflect advances in the field over the last 10 years and expanded to include chapters on natamycin, bacteriocins, indirect antimicrobials, and methods for evaluation. Other revisions include revision of the chapters on nisin and natural antimicrobials. The editors compiled this reference in a cohesive, quick-access format that makes this the perfect guide for food scientists.

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Yeast Protocols

Yeast Protocols (Methods in Molecular Biology)
by Wei Xiao (Editor)

Product Details:
* Hardcover: 392 pages
* Publisher: Humana Press; 2 edition (September 1, 2005)
* Language: English
* ISBN-10: 1588294374

Book Description
In this second edition of a widely used classic laboratory manual, leading experts utilize the tremendous progress and technological advances that have occurred to create a completely new collection of not only the major basic techniques, but also advanced protocols for yeast research and for using yeast as a host to study genes from other organisms. The authors provide detailed methods for the isolation of subcellular components-including organelles and macromolecules, for the basic cellular and molecular analysis specific for yeast cells, and for the creation of conditional mutant phenotypes that lend themselves to powerful genome manipulation. Additional protocols offer advanced approaches to study genetic interactions, DNA and chromatin metabolism, gene expression, as well as the foreign genes and gene products in yeast cells.

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Polyomaviruses and Human Diseases

Polyomaviruses and Human Diseases (Advances in Experimental Medicine and Biology) (Advances in Experimental Medicine and Biology)
by Nasimul Ahsan (Editor)

Product Details:
* Hardcover: 387 pages
* Publisher: Springer; 1 edition (February 1, 2006)
* Language: English
* ISBN-10: 0387292330

Book Description
This book explains the means of diagnosis and treatment of polyomavirus and contains an ample outline of the history, pathology, symptoms, and treatment of diseases induced by human polyomavirus. This volume is divided into four sections which thoroughly explore the most up to date information on polyomavirus including a general discussion of the virus, exploration of transplant related pathobiology, histopathology, diagnosis, management, and pharmacotherapy, afflictions and diseases caused by polyoma-JC virus and neoplastic associations of polyomaviruses. This comprehensive text will provide the reader with information on all of the latest advancements in the area.

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AIDS/HIV

AIDS/Hiv (Information Plus Reference Series)
by Brian Hoyle (Author)

Product Details:
* Paperback: 132 pages
* Publisher: Thomson Gale (May 5, 2006)
* Language: English
* ISBN-10: 1414404042

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Fungal Genomics, Volume 57: Advances in Genetics

Fungal Genomics, Volume 57: Advances in Genetics
by Jay C. Dunlap (Editor)

Product Details:
* Hardcover: 320 pages
* Publisher: Academic Press; 1 edition (March 9, 2007)
* Language: English
* ISBN-10: 0120176572

Book Description
The sequencing of several fungi genomes has spurred major advances in the field. Fungal genomics has been having a pivotal impact on applied research in agriculture, food sciences, natural resource management, pharmaceuticals, and biotechnology, as well as to basic studies in the life sciences. This volume covers exciting new developments in this growth field, from genomic analysis to human fungal pathogen genomics, comparative genomics of fungi, and the genomics of fungal development.
* Includes information on aspergillus genomes
* Discusses sex and its role in virulence of human fungal pathogens
* Covers the genomic analysis of neurospora

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Escherichia coli: Virulence Mechanisms of a Versatile Pathogen

Escherichia coli: Virulence Mechanisms of a Versatile Pathogen
by Michael Donnenberg (Editor)

Product Details:
* Hardcover: 417 pages
* Publisher: Academic Press; 1st edition (September 10, 2002)
* Language: English
* ISBN-10: 0122207513

Book Description:
Escherichia coli: Virulence Mechanisms of a Versatile Pathogen is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Escherichia coli: Virulence Mechanisms of a Versatile Pathogen concludes with a presentation of virulence factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research.

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New Challenges to Health: The Threat of Virus Infection

New Challenges to Health: The Threat of Virus Infection
by G. L. Smith (Editor), W. L. Irving (Editor), J. W. McCauley (Editor), D. J. Rowlands (Editor)

Product Details:
* Hardcover: 347 pages
* Publisher: Cambridge University Press; 1st edition (May 15, 2001)
* Language: English
* ISBN-10: 0521806143

Book Description
This book discusses the ecology of viruses with an emphasis on the emergence of devastating hemorrhagic diseases, and a review of the molecular and cellular basis of the pathogenesis of several viral diseases. The volume provides an introduction to the mathematical analysis of recurrent epidemic viral diseases and examines the neurological and psychological diseases in relation to the pathological mechanisms underlying prion disease. Chapters explore new viral threats including HIV, bunyaviruses, morbilliviruses and caliciviruses.

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Listeria monocytogenes: Pathogenesis and Host Response

Listeria monocytogenes: Pathogenesis and Host Response
by Howard Goldfine (Editor), Hao Shen (Editor)

Product Details:
* Hardcover: 288 pages
* Publisher: Springer; 1 edition (April 11, 2007)
* Language: English
* ISBN-10: 0387493735

Book Description
This volume includes research from the studies at the molecular level on the pathogenesis of Listeria monocytogenes and the response of the host to its infections. During the past twenty years Listeria monocytogenes has emerged as one of the most intensely studied bacterial pathogens. New windows are constantly being opened into the complexity of host cell biology and the interplay of the signals connecting the various cells and organs involved in the host response. As revealed in many of the chapters in this volume, the study of L. monocytogenes has already provided major insights into eukaryotic cell biology.

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AIDS Epidemiology: A Quantitative Approach

AIDS Epidemiology: A Quantitative Approach (Monographs in Epidemiology and Biostatistics ; V. 22)
by Ron Brookmeyer (Author), Mitchell H. Gail (Author)

Product Details:
* Paperback: 376 pages
* Publisher: Oxford University Press, USA (December 21, 1993)
* Language: English
* ISBN-10: 0195076419

Book Description
AIDS has appeared in more than 130 countries, and over 100,000 cases of AIDS have been reported in the U.S. alone. More and more, the public will be depending on statisticians to provide answers about the future course of this epidemic. This comprehensive work confronts the problems that are unique to AIDS research and unites them under a single conceptual framework. It focuses on methods for the design and analysis of epidemiologic studies, the natural history of AIDS and the transmission of HIV, methods for tracking and projecting the course of the epidemic, and statistical issues in therapeutic trials. The various methods of monitoring and forecasting this disease receive comprehensive treatment. These methods include back-calculation, which the authors developed; interpretation of survey data on HIV prevalence; mathematical models for HIV transmission; and approaches that combine different types of epidemiological data. Much of this material -- such as a discussion of methods for assessing safety of the blood supply, an evaluation of survey approaches, and methods to project pediatric AIDS incidence -- is not available in any other work.

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Microbe-vector Interactions in Vector-borne Diseases

Microbe-vector Interactions in Vector-borne Diseases (Society for General Microbiology Symposia)
by Stephen H. Gillespie (Editor), Geoffrey L. Smith (Editor), Anne Osbourn (Editor)

Product Details:
* Hardcover: 396 pages
* Publisher: Cambridge University Press (May 10, 2004)
* Language: English
* ISBN-10: 052184312X

Book Description
Several billion people are at daily risk of life-threatening vector-borne diseases such as malaria, trypanosomiasis and dengue. This volume describes the way in which the causal pathogens of such diseases interact with the vectors that transmit them, detailing the biological adaptations that enable pathogens to live with their vectors and, in some circumstances, to control them. This knowledge has led to novel preventative strategies in the form of antibiotics and new vaccines which are targeted not at the pathogen itself but at its specific vector.

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Molecular Diagnostics

Molecular Diagnostics
by George Patrinos (Editor), Wilhelm Ansorge (Editor)

Product Details:
* Hardcover: 488 pages
* Publisher: Academic Press (June 6, 2005)
* Language: English
* ISBN-10: 0125466617

Book Description
Molecular Diagnostics covers current molecular biological techniques used to identify the underlying molecular defects in inherited disease. Although an increasing number of laboratories, both academic and private are moving in that direction, there are only a few books in the existing literature, and they deal only partly with diagnosis at the molecular level. Each chapter includes the principle and a brief description of the technique, followed by exmples from the authors' own epertise. Contributors are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage.
* Examines widely used molecular biology techniques to screen for genetic defects causing inherited disorders
* Includes state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders
* Identification of genetically modified organisms (GMO's)
* Forensic analysis and every-day issues in a diagnostic laboratory
* Discusses ethics, genetic counselling and quality management

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The Ecology of Cyanobacteria - Their Diversity in Time and Space

The Ecology of Cyanobacteria - Their Diversity in Time and Space
by B.A. Whitton (Editor), M. Potts (Editor)

Product Details:
* Paperback: 704 pages
* Publisher: Springer; 1 edition (June 1, 2000)
* Language: English
* ISBN-10: 0792347552

Book Description
Cyanobacteria make a major contribution to world photosynthesis and nitrogen fixation, but are also notorious for causing nuisances such as dense and often toxic `blooms' in lakes and the ocean. The Ecology of Cyanobacteria: Their Diversity in Time and Space is the first book to focus solely on ecological aspects of these organisms. Its twenty-two chapters are written by some thirty authors, who are leading experts in their particular subject. The book begins with an overview of the cyanobacteria - or blue-green algae, for those who are not specialists - then looks at their diversity in the geological record and goes on to describe their ecology in present environments where they play important roles. Why is one of the key groups of organisms in the Precambrian still one of the most important groups of phototrophs today? The importance of ecological information for rational management and exploitation of these organisms for commercial and other practical purposes is also assessed. Accounts are provided of nuisances as well as the ecology of the commercially successful Spirulina and the role of cyanobacteria in ecosystem recovery from oil pollution. Many chapters include aspects of physiology, biochemistry, geochemistry and molecular biology where these help general understanding of the subject. In addition there are three chapters dealing specifically with molecular ecology. Thirty-two pages of colour photos incorporate about seventy views and light micrographs. These features make the book valuable to a wide readership, including biologists, microbiologists, geologists, water managers and environmental consultants. The book complements the highly successful The Molecular Biology of Cyanobacteria already published by Kluwer.

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Advanced Techniques in Diagnostic Microbiology

Advanced Techniques in Diagnostic Microbiology
by Yi-Wei Tang (Editor), Charles W. Stratton (Editor)

Product Details:
* Hardcover: 540 pages
* Publisher: Springer; 1 edition (June 16, 2006)
* Language: English
* ISBN-10: 0387297413

Book Description
Clinical microbiologists are engaged in the field of diagnostic microbiology to determine whether pathogenic microorganisms are present in clinical specimens collected from patients with suspected infections. If microorganisms are found, these are identified and susceptibility profiles, when indicated, are determined. During the past two decades, technical advances in the field of diagnostic microbiology have made constant and enormous progress in various areas, including bacteriology, mycology, mycobacteriology, parasitology, and virology. The diagnostic capabilities of modern clinical microbiology laboratories have improved rapidly and have expanded greatly due to a technological revolution in molecular aspects of microbiology and immunology. In particular, rapid techniques for nucleic acid amplification and characterization combined with automation and user-friendly software have significantly broadened the diagnostic arsenal for the clinical microbiologist. The conventional diagnostic model for clinical microbiology has been labor-intensive and frequently required days to weeks before test results were available. Moreover, due to the complexity and length of such testing, this service was usually directed at the hospitalized patient population. The physical structure of laboratories, staffing patterns, workflow, and turnaround time all have been influenced profoundly by these technical advances. Such changes will undoubtedly continue and lead the field of diagnostic microbiology inevitably to a truly modern discipline. Advanced Techniques in Diagnostic Microbiology provides a comprehensive and up-to-date description of advanced methods that have evolved for the diagnosis of infectious diseases in the routine clinical microbiology laboratory. The book is divided into two sections. The first techniques section covers the principles and characteristics of techniques ranging from rapid antigen testing, to advanced antibody detection, to in vitro nucleic acid amplification techniques, and to nucleic acid microarray and mass spectrometry. Sufficient space is assigned to cover different nucleic acid amplification formats that are currently being used widely in the diagnostic microbiology field. Within each technique, examples are given regarding its application in the diagnostic field. Commercial product information, if available, is introduced with commentary in each chapter. If several test formats are available for a technique, objective comparisons are given to illustrate the contrasts of their advantages and disadvantages. The second applications section provides practical examples of application of these advanced techniques in several "hot" spots in the diagnostic field. A diverse team of authors presents authoritative and comprehensive information on sequence-based bacterial identification, blood and blood product screening, molecular diagnosis of sexually transmitted diseases, advances in mycobacterial diagnosis, novel and rapid emerging microorganism detection and genotyping, and future directions in the diagnostic microbiology field. We hope our readers like this technique-based approach and your feedback is highly appreciated. We want to thank the authors who devoted their time and efforts to produce their chapters. We also thank the staff at Springer Press, especially Melissa Ramondetta, who initiated the whole project. Finally, we greatly appreciate the constant encouragement of our family members through this long effort. Without their unwavering faith and full support, we would never have had the courage to commence this project.

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Oceans and Health:: Pathogens in the Marine Environment

Oceans and Health:: Pathogens in the Marine Environment
by Shimshon S. Belkin (Editor), Rita R. Colwell (Editor)

Product Details:
* Hardcover: 464 pages
* Publisher: Springer; 1 edition (September 30, 2005)
* Language: English
* ISBN-10: 0387237089

Book Description
The release of non-disinfected wastewaters into the marine environment is a common worldwide practice, in under-developed as well as in highly developed countries. Consequently, the seas are constantly infused with wastewater bacteria, among them highly pathogenic ones.
In view of the public health significance of this phenomenon, it is surprising how little is actually known concerning the fate of such bacteria once they enter the sea. While numerous studies have addressed the effects of various environmental parameters on colony formation, many of them actually ignore the fact that bacteria can retain viability and infectivity while losing colony-forming ability.
Only in recent years have efforts also been directed at unraveling the mechanisms determining bacterial sensitivity or survival under these conditions. This, therefore, is one subject of Oceans and Health: Pathogens in the Marine Environment: the survival, infectivity, pathogenicity and viability of enteric bacteria in the sea. Chapters also detail the public health aspects of wastewater release, civil engineering and economic considerations, other sources of pathogens, and much more.

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Immunochemical Protocols

Immunochemical Protocols (Methods in Molecular Biology)
by Robert Burns (Editor)

Product Details:
* Hardcover: 328 pages
* Publisher: Humana Press; 3 edition (December 13, 2004)
* Language: English
* ISBN-10: 1588292746

Book Description
This new edition of a much praised classic includes both basic method for producing and using antibodies and advanced techniques required by today's state-of-the art investigators. The basic sections of the book stress the first principles of antibody production and guide the reader through the processes and pitfalls of immunochemistry. The advanced sections focus on specific applications and cover the immunochemical techniques now used in laboratories. New material includes techniques for making new monoclonal cell lines, for producing good quality monoclonal antibodies, immunocapture PCR, immunoaffinity purification, and immunoelectron microscopy in plant virus diagnosis.

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Childhood tuberculosis an Issue of Paediatric Respiratory Reviews

Childhood tuberculosis an Issue of Paediatric Respiratory Reviews

Product Details
* Format: Magazine
* Shipping: Currently, item can be shipped only within the U.S.
* Publisher: Elsevier
* ASIN: B00007B0C5

Book Description
Publishes articles relevant to pediatricians specializing in the diagnosis, treatment and management of respiratory disease. Subjects covered include: epidemiology, immunology and cell biology, physiology, occupational disorders,and the role of allergens and pollutants.
hildhood tuberculosis: new recognition of an old disease
Childhood tuberculosis – global epidemiology and the impact of HIV
Clinical manifestations of tuberculosis in children
Airway involvement in pulmonary tuberculosis
New approaches and emerging technologies in the diagnosis of childhood tuberculosis
Old and new drugs for the treatment of tuberculosis in children
Tuberculosis and human immunodeficiency virus co-infection in children: management challenges
Childhood tuberculosis: old and new vaccines
Vocal cord dysfunction in children
Treatment approaches for empyema in children
The European Regulation on medicines for paediatric use

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Immunotoxicology and Risk Assessment

Immunotoxicology and Risk Assessment
by Dennis K. Flaherty (Author)

Product Details:
* Hardcover: 374 pages
* Publisher: Springer; 1st edition (May 31, 1999)
* Language: English
* ISBN-10: 030645971X

Book Description
This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology focus on hazard identification, appropriate assays, dose response, and risk assesment by mathematical models and safety factors. It will be a useful reference to toxicologists because it will incorporate new guidelines that the EPA is bringing out later this year for all chemicals regulated under the Federal Insecticide, Fungicide, and Rodenticide Act and the Toxic Substances Control Act. Regulatory sections in each chapter focus on data from both the US Food and Drug Administration, as well as data applicable to western European Nations.

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Modulation of Host Gene Expression and Innate Immunity by Viruses

Modulation of Host Gene Expression and Innate Immunity by Viruses
by Peter Palese (Editor), Jean-Pierre Changeux (Editor)

Product Details:
* Hardcover: 304 pages
* Publisher: Springer; 1 edition (March 8, 2005)
* Language: English
* ISBN-10: 1402032412

Book Description
This book is an excellent, up-to-date reference on a relatively young area of research in which virology, cellular biology and molecular pathogenesis govern the principles of coinvestigation. Thus, the book will be of great interest to virologists, molecular immunologists and biologists, and biochemists but also to clinical pharmacologists in the long-term search for new antiviral agents. Ulrich Desselberger, Gif-sur-Yvette/Cambridge.
Infection of a naïve (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity). The outcome of this interaction is influenced by the genes of the virus as well as the genes of the host. Interestingly, different viruses do it in different ways. Not only is there a plethora of mechanisms used by the invading organisms, but the host has also evolved a great variety of redundant and robust countermeasures. This interplay of host and virus represents one of the most significant frontiers in biology today. A clearer understanding of the mechanisms involved will arm us with better strategies to deal with viruses, including emerging pathogens and potential bioterrorism agents. This book is sure to benefit students, scientists, and physicians working in the areas of virology, immunology, microbiology, and infectious diseases. Pharmaceutical industry professionals will also find interest in this illuminating look into virus/host interactions.

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Immunotherapy in 2020: Visions and Trends for Targeting Inflammatory Disease

Immunotherapy in 2020: Visions and Trends for Targeting Inflammatory Disease (Ernst Schering Foundation Symposium Proceedings)
by Andreas Radbruch (Editor), Hans-Dieter Volk (Editor), Khusru Asadullah (Editor), Wolf-Dietrich Döcke (Editor)

Product Details:
* Hardcover: 121 pages
* Publisher: Springer; 1 edition (August 2007)
* Language: English
* ISBN-10: 3540708502

Book Description
This volume features contributions from participants of the ESRF symposium on "Immunotherapy in 2020—Visions and Trends for Targeting Inflammatory Diseases" held in Potsdam near Berlin, Germany, in October 2006.
The symposium presentations covered the main mechanisms of immunoregulation such as peripheral and central tolerance, epigenetic programming, immunologic memory, and regulatory networks in inflammation as well as novel experimental and clinical approaches for targeting inflammation in autoimmunity and transplantation. An important related question is how recent findings in immunological research can lead to improved diagnostics, new drugs, and better therapies. The targeting of novel pathways and immunoregulatory mechanisms, the challenge of immunologic memory for lastingly successful anti-inflammatory therapy, new approaches for adoptive T cell and polyclonal antibody therapies, and the individualization of immunomodulatory therapies are thereby topics of this volume.

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Modeling Microbial Responses in Food

Modeling Microbial Responses in Food (Contemporary Food Science)
by Robin C. McKellar (Editor), Xuewen Lu (Editor)

Product Details;
* Hardcover: 360 pages
* Publisher: CRC (December 29, 2003)
* Language: English
* ISBN-10: 084931237X

Book Description;
Modeling Microbial Responses in Foods is the first state-of-the-art review of this dynamic field in a decade. The comprehensive coverage includes basic approaches, such as improvements in the development of primary and secondary models, statistical fitting strategies, and novel data collection methods. The authors explore important developing areas, including specific applications, challenges in applying models to foods, variability and uncertainly, and new modeling strategies. They provide detailed descriptions of non-linear regression fitting, methods, and approaches relevant to 'real world' situations, and extensive applications of predictive models.

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Pathogenomics: Genome Analysis of Pathogenic Microbes

Pathogenomics: Genome Analysis of Pathogenic Microbes
by Werner Göbel (Foreword), Jörg Hacker (Editor), Ulrich Dobrindt (Editor)

Product Details:
* Hardcover: 616 pages
* Publisher: Wiley-VCH (March 20, 2006)
* Language: English
* ISBN-10: 352731265X

Book Description
The first book on this young, highly dynamic, and expanding field.
This comprehensive, interdisciplinary text focuses on those pathogenic bacteria that are of high scientific and public health interest, yet which also display great potential for the development of new diagnostic, prophylactic and therapeutic procedures.
The authors cover all aspects of pathogenomics, including methods, genomics and applications. In addition, the ongoing development of genome, transcriptome, proteome and bioinformatic analyses of pathogenic microorganisms and their host interactions makes for a comprehensive introduction to the field of modern genomic analysis.
This result is invaluable to researchers and students wishing to gain a general overview of microbial functional genome analysis and pathogenesis, while also representing a good starting point for those new to the area.

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Extremophiles

Extremophiles, Volume 35 (Methods in Microbiology)
by Fred Rainey (Editor), Aharon Oren (Editor)

Product Details:
* Hardcover: 838 pages
* Publisher: Academic Press (August 18, 2006)
* Language: English
* ISBN-10: 0125215363

Book Description
This latest volume in the Methods in Microbiology series provides an overview of the methods used for the isolation, cultivation and handling of a wide variety of extremophiles, both at the stage of their isolation from natural samples and in pure culture. It contains protocols specific for work with extremophiles, as well as adaptations of standard microbiology protocols modified to enable the handling of extremophiles. Emphasis will be on detailed time-tested protocols that are specific for work with extremophiles and adaptations of standard microbiology protocols that have to be modified to be suitable for handling extremophiles.
* Guides newcomers in the field of extremophile microbiology in the techniques used
* Provides an overview of all areas of extremophile research
* Many protocols could be adapted for use with a wide range of organisms

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Promise and Challenges in Systems Microbiology

Promise and Challenges in Systems Microbiology: Workshop Summary
by Patricia McAdams (Author), Evonne Tang (Author)

Product Details:
* Paperback: 36 pages
* Publisher: National Academy Press (March 2, 2004)
* Language: English
* ISBN-10: 0309091675

Table of Contents
Front Matter i-xii
1 Introduction 1-2
2 Workshop Proceedings 3-26
3 Summary of Key Points 27-28
Appendix A: Agenda 29-30
Appendix B: Participant Biographies 31-36

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Environmental Pollution Control Microbiology

Environmental Pollution Control Microbiology: A Fifty-Year Perspective
by Ross E. McKinney (Author)

Product Details:
* Textbook Binding: 448 pages
* Publisher: CRC; New Ed edition (March 1, 2004)
* Language: English
* ISBN-10: 082475493X

Book Description:
Environmental Pollution Control Microbiology: A Fifty-Year Perspective illustrates the application of fundamental concepts in microbiology to provide a sound basis for the design and operation of various biological systems used in solving environmental challenges involving air, water, and soil. This book emphasizes the quantitative relationships of microbial growth and metabolism, beginning with an examination of overall metabolism and resulting growth of bacteria, fungi, algae, protozoa, rotifers, and other microorganisms. It explains how bacteria bring about the stabilization of biodegradable organic pollutants. The text also discusses the proper environmental conditions for optimizing microbial stabilization.

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Molecular Diagnostics: For the Clinical Laboratorian

Molecular Diagnostics: For the Clinical Laboratorian
by William B. Coleman (Editor), Gregory J. Tsongalis (Editor)

Product Details:
* Hardcover: 592 pages
* Publisher: Humana Press; 2 edition (August 15, 2005)
* Language: English
* ISBN-10: 1588293564

Book Description
This updated and expanded tutorial guide to molecular diagnostic techniques takes advantage of many new molecular technologies to include both improved traditional methods and totally new methods, some not yet in routine use. The authors offer cutting-edge molecular diagnostics for genetic disease, human cancers, infectious diseases, and identity testing, as well as new insights into the question of quality assurance in the molecular diagnostics laboratory. Additional chapters address other technologies found in the clinical laboratory that complementary to molecular diagnostic technologies and discuss genetic counseling and the ethical and social issues involved with nucleic acid testing. A value-added compact disk containing a companion e-book version of the book, is included for downloading and use in the reader's PC or PDA.

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